Expression differences for genes involved in lignin, glutathione and sulphate metabolism in response to cadmium in Arabidopsis thaliana and the related Zn/Cd‐hyperaccumulator Thlaspi caerulescens
Open accessAbstract
Cadmium (Cd) is a widespread, naturally occurring element present in soil, rock, water, plants and animals. Cd is a non-essential element for plants and is toxic at higher concentrations. Transcript profiles of roots of Arabidopsis thaliana (Arabidopsis) and Thlaspi caerulescens plants exposed to Cd and zinc (Zn) are examined, with the main aim to determine the differences in gene expression between the Cd-tolerant Zn-hyperaccumulator T. caerulescens and the Cd-sensitive non-accumulator Arabidopsis. This comparative transcriptional analysis emphasized the role of genes involved in lignin, glutathione and sulphate metabolism. Furthermore the transcription factors MYB72 and bHLH100 were studied for their involvement in metal homeostasis, as they showed an altered expression after exposure to Cd. The Arabidopsis myb72 knockout mutant was more sensitive to excess Zn or iron (Fe) deficiency than wild type, while Arabidopsis transformants overexpressing bHLH100 showed increased tolerance to high Zn and nickel (Ni) compared to wild-type plants, confirming their role in metal homeostasis in Arabidopsis.
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- Authors
- VAN DE MORTEL, J. E., SCHAT, H., MOERLAND, P. D., VAN THEMAAT, E. V. L., VAN DER ENT, S., BLANKESTIJN, H., GHANDILYAN, A., TSIATSIANI, S., & AARTS, M. G. M.
- Affiliations
- Vrije Universiteit Amsterdam (NL)
- Amsterdam UMC Location University of Amsterdam (NL)
- Wageningen University & Research (NL)
- Venue
- Plant, Cell & Environment
- Publisher
- Wiley
- Published
- 2007-12-10
- Volume
- 31
- Issue
- 3
- Pages
- 301-324
- ISSN
- 0140-7791 (ISSN-L)
- 1365-3040
- OpenAlex
- W2164314453
- Cited by
- 326
- References
- 87
- Citations by year
- 2026: 6 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 26 · 2021: 18 · 2020: 22 · 2019: 23 · 2018: 26 · 2017: 14 · 2016: 14 · 2015: 18 · 2014: 20 · 2013: 16 · 2012: 22
- FWCI
- 16.61
- Type
- journal article
- Language
- en
- Open access
- green
- research.wur.nl
- Locations
- Plant Cell & Environment (publishedVersion)
- PubMed (publishedVersion)
- VU Research Portal (publishedVersion)
- Socio-Environmental Systems Modeling (acceptedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
- Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Micronutrient Interactions and Effects
- Keywords
- cadmium toxicity, zinc hyperaccumulation, Thlaspi caerulescens, Arabidopsis thaliana, lignin metabolism, glutathione metabolism, sulfate metabolism, metal homeostasis, transcriptional response, zinc tolerance, nickel tolerance, iron deficiency, root transcriptome
- MeSH terms
- Cadmium, Glutathione, Iron, Lignin, Nickel, Plant Proteins, Sulfates, Transcription, Genetic, Zinc, Genes, Plant, Arabidopsis, Gene Expression Regulation, Plant, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Thlaspi
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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