Cited by 326Plant Stress Responses and ToleranceHeavy metals in environmentPlant Micronutrient Interactions and Effects

Expression differences for genes involved in lignin, glutathione and sulphate metabolism in response to cadmium in Arabidopsis thaliana and the related Zn/Cd‐hyperaccumulator Thlaspi caerulescens

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VAN DE MORTEL, JUDITH E., SCHAT, HENK, MOERLAND, PERRY D., VAN THEMAAT, EMIEL VER LOREN, VAN DER ENT, SJOERD, BLANKESTIJN, HETTY, GHANDILYAN, ARTAK, TSIATSIANI, STYLIANI +1 more·2008·Plant, Cell & Environment

Abstract

Cadmium (Cd) is a widespread, naturally occurring element present in soil, rock, water, plants and animals. Cd is a non-essential element for plants and is toxic at higher concentrations. Transcript profiles of roots of Arabidopsis thaliana (Arabidopsis) and Thlaspi caerulescens plants exposed to Cd and zinc (Zn) are examined, with the main aim to determine the differences in gene expression between the Cd-tolerant Zn-hyperaccumulator T. caerulescens and the Cd-sensitive non-accumulator Arabidopsis. This comparative transcriptional analysis emphasized the role of genes involved in lignin, glutathione and sulphate metabolism. Furthermore the transcription factors MYB72 and bHLH100 were studied for their involvement in metal homeostasis, as they showed an altered expression after exposure to Cd. The Arabidopsis myb72 knockout mutant was more sensitive to excess Zn or iron (Fe) deficiency than wild type, while Arabidopsis transformants overexpressing bHLH100 showed increased tolerance to high Zn and nickel (Ni) compared to wild-type plants, confirming their role in metal homeostasis in Arabidopsis.

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Crossref · 10.1111/j.1365-3040.2007.01764.x

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Authors
VAN DE MORTEL, J. E., SCHAT, H., MOERLAND, P. D., VAN THEMAAT, E. V. L., VAN DER ENT, S., BLANKESTIJN, H., GHANDILYAN, A., TSIATSIANI, S., & AARTS, M. G. M.
Affiliations
  • Vrije Universiteit Amsterdam (NL)
  • Amsterdam UMC Location University of Amsterdam (NL)
  • Wageningen University & Research (NL)
Venue
Plant, Cell & Environment
Publisher
Wiley
Published
2007-12-10
Volume
31
Issue
3
Pages
301-324
ISSN
  • 0140-7791 (ISSN-L)
  • 1365-3040
OpenAlex
W2164314453
Cited by
326
References
87
Citations by year
2026: 6 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 26 · 2021: 18 · 2020: 22 · 2019: 23 · 2018: 26 · 2017: 14 · 2016: 14 · 2015: 18 · 2014: 20 · 2013: 16 · 2012: 22
FWCI
16.61
Type
journal article
Language
en
Open access
Locations
  • Plant Cell & Environment (publishedVersion)
  • PubMed (publishedVersion)
  • VU Research Portal (publishedVersion)
  • Socio-Environmental Systems Modeling (acceptedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
  • Pure Amsterdam UMC (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
  • Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Micronutrient Interactions and Effects
Keywords
cadmium toxicity, zinc hyperaccumulation, Thlaspi caerulescens, Arabidopsis thaliana, lignin metabolism, glutathione metabolism, sulfate metabolism, metal homeostasis, transcriptional response, zinc tolerance, nickel tolerance, iron deficiency, root transcriptome
MeSH terms
Cadmium, Glutathione, Iron, Lignin, Nickel, Plant Proteins, Sulfates, Transcription, Genetic, Zinc, Genes, Plant, Arabidopsis, Gene Expression Regulation, Plant, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Thlaspi

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