Genetic architecture of zinc hyperaccumulation in Arabidopsis halleri: the essential role of QTL × environment interactions
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SUMMARY: This study sought to determine the main genomic regions that control zinc (Zn) hyperaccumulation in Arabidopsis halleri and to examine genotype x environment effects on phenotypic variance. To do so, quantitative trait loci (QTLs) were mapped using an interspecific A. halleri x Arabidopsis lyrata petraea F(2) population. *The F(2) progeny as well as representatives of the parental populations were cultivated on soils at two different Zn concentrations. A linkage map was constructed using 70 markers. *In both low and high pollution treatments, zinc hyperaccumulation showed high broad-sense heritability (81.9 and 74.7%, respectively). Five significant QTLs were detected: two QTLs specific to the low pollution treatment (chromosomes 1 and 4), and three QTLs identified at both treatments (chromosomes 3, 6 and 7). These QTLs explained 50.1 and 36.5% of the phenotypic variance in low and high pollution treatments, respectively. Two QTLs identified at both treatments (chromosomes 3 and 6) showed significant QTL x environment interactions. *The QTL on chromosome 3 largely colocalized with a major QTL previously identified for Zn and cadmium (Cd) tolerance. This suggests that Zn tolerance and hyperaccumulation share, at least partially, a common genetic basis and may have simultaneously evolved on heavy metal-contaminated soils.
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Many studies have reported on two Zn/Cd hyperaccumulator models, T. caerulescens and A. halleri.
“Many studies have reported on two Zn/Cd hyperaccumulator models, T. caerulescens and A. halleri (Frérot et al., 2010; Krämer, 2010).”
From Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration (2025) · cites this paper as Frérot et al., 2010
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- Authors
- Frérot, H., Faucon, M., Willems, G., Godé, C., Courseaux, A., Darracq, A., Verbruggen, N., & Saumitou‐Laprade, P.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Université Libre de Bruxelles (BE)
- Corresponding author
- Frérot, Hélène
- ORCID
- Venue
- New Phytologist
- Publisher
- Wiley
- Published
- 2010-05-12
- Volume
- 187
- Issue
- 2
- Pages
- 355-367
- ISSN
- 0028-646X (ISSN-L)
- 1469-8137
- OpenAlex
- W2141746967
- Cited by
- 85
- References
- 75
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2022: 2 · 2021: 2 · 2020: 11 · 2019: 8 · 2018: 4 · 2017: 2 · 2016: 4 · 2015: 8 · 2014: 4 · 2013: 12 · 2012: 9
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New Phytologist (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion, other-oa)
- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Micronutrient Interactions and Effects
- Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
- Keywords
- zinc hyperaccumulation, Arabidopsis halleri, quantitative trait loci, QTL-by-environment interaction, gene-environment interaction, heavy metal tolerance, cadmium tolerance, heritability, F2 population, genetic linkage map, heavy metal-contaminated soil, genetic architecture
- MeSH terms
- Analysis of Variance, Chromosome Mapping, Environment, Environmental Pollutants, Genetic Markers, Zinc, Arabidopsis, Quantitative Trait, Heritable, Chromosome Segregation, Quantitative Trait Loci
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