Pregnancy outcome in women with peritoneal, ovarian and rectovaginal endometriosis: a retrospective cohort study
Open accessAbstract
Please cite this paper as: Vercellini P, Parazzini F, Pietropaolo G, Cipriani S, Frattaruolo M, Fedele L. Pregnancy outcome in women with peritoneal, ovarian and rectovaginal endometriosis: a retrospective cohort study. BJOG 2012;119:1538–1543. We retrospectively assessed pregnancy outcome in 419 women who achieved a first spontaneous singleton pregnancy after surgery for endometriosis. A miscarriage was observed in 87 of 419 women (20.8%) and an ectopic pregnancy in eight (1.9%). Among the remaining 324 women, 14 (4.3%) experienced gestational hypertension/pre‐eclampsia, 38 (11.7%) had a preterm delivery, five (1.5%) had placental abruption and 12 (3.7%) had placenta praevia. The incidence of placenta praevia was 7.6% in 150 women with rectovaginal lesions, 2.1% in 69 with ovarian endometriomas plus peritoneal implants, and 2.4% in 100 women with peritoneal implants only, whereas no case was observed in 100 women with ovarian endometriomas only.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A recent retrospective study of pregnancy outcome in women with peritoneal, ovarian, and rectovaginal endometriosis found elevated levels of miscarriage, ectopic pregnancy, gestational hypertension/preeclampsia, preterm delivery, placental abruption, and placenta praevia.
“A recent retrospective study of pregnancy outcome in women with peritoneal, ovarian, and rectovaginal endometriosis found elevated levels of miscarriage, ectopic pregnancy, gestational hypertension/preeclampsia, preterm delivery, placental abruption, and placenta praevia.39,40”
From Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France (2013) · cites this paper as [39]
Retrospective studies have suggested that women with endometriosis may have higher rates of maternal complications and fetal problems such as preeclampsia and miscarriage, though these associations need further study.
“Retrospective studies have suggested that women with endometriosis may have higher rates of maternal complications and fetal problems such as preeclampsia and miscarriage (46–50), though these associations need further study.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Revised American Fertility Society Classification of Endometriosis: 1985
(1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48430-x · Cited by 1,803 · see citing works
Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome
Stephansson, O., Kieler, H., Granath, F., & Falconer, H. (2009) · Human Reproduction · doi:10.1093/humrep/dep186 · Cited by 234 · see citing works
Kunz, G., Beil, D., Huppert, P., & Leyendecker, G. (2000) · Human Reproduction · doi:10.1093/humrep/15.1.76 · Cited by 177 · see citing works
Obstetric outcome in women with subfertility
THOMSON, F. J., Shanbhag, S., Templeton, A. A., et al. (2005) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2004.00489.x · Cited by 167 · see citing works
Preterm birth, ovarian endometriomata, and assisted reproduction technologies
Fernando, S., Breheny, S., Jaques, A. M., Halliday, J. L., Baker, G., & Healy, D. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.01.096 · Cited by 150 · see citing works
Risks of adverse pregnancy outcome in endometriosis
Brosens, I., Brosens, J. J., Fusi, L., Al-Sabbagh, M., Kuroda, K., & Benagiano, G. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.02.024 · Cited by 132 · see citing works
Endometriosis, recurrent miscarriage and implantation failure: is there an immunological link?
Tomassetti, C., Meuleman, C., Pexsters, A., Mihalyi, A., Kyama, C., Simsa, P., & D'Hooghe, T. (2006) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)62016-0 · Cited by 106 · see citing works
Endometriosis is associated with a decreased risk of pre-eclampsia
Brosens, I. A., Sutter, P. D., Hamerlynck, T. W. O., Imeraj, L., Yao, Z., Cloke, B., Brosens, J. J., & Dhont, M. A. (2007) · Human Reproduction · doi:10.1093/humrep/dem072 · Cited by 97 · see citing works
Hadfield, R. M., Lain, S. J., Raynes‐Greenow, C. H., Morris, J. M., & Roberts, C. (2009) · Human Reproduction · doi:10.1093/humrep/dep123 · Cited by 73 · see citing works
Obstetric Outcome in Women with Endometriosis – A Matched Case-Control Study
Kortelahti, M., Anttila, M. A., Hippeläinen, M. I., & Heinonen, S. T. (2003) · Gynecologic and Obstetric Investigation · doi:10.1159/000074815 · Cited by 59 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Guerriero, S., Condous, G., van den Bosch, T., Valentin, L., Leone, F. P. G., Van Schoubroeck, D., Exacoustos, C., Installé, A. J. F., Martins, W. P., Abrao, M. S., et al. (2016) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.15955 · Cited by 900 · see citing works
Vitonis, A. F., Vincent, K., Rahmioglu, N., Fassbender, A., Buck Louis, G. M., Hummelshoj, L., Giudice, L. C., Stratton, P., Adamson, G. D., Becker, C. M., et al. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2014.07.1244 · Cited by 236 · see citing works
Endometriosis and obstetrics complications: A systematic review and meta-analysis
Zullo, F., Spagnolo, E., Saccone, G., Acunzo, M., Xodo, S., Ceccaroni, M., & Berghella, V. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.07.019 · Cited by 227 · see citing works
Barragan, F., Irwin, J. C., Balayan, S., Erikson, D. W., Chen, J. C., Houshdaran, S., Piltonen, T. T., Spitzer, T. L. B., George, A., Rabban, J. T., et al. (2016) · Biology of Reproduction · doi:10.1095/biolreprod.115.136010 · Cited by 152 · see citing works
Rogers, P. A. W., D’Hooghe, T. M., Fazleabas, A., Giudice, L. C., Montgomery, G. W., Petraglia, F., & Taylor, R. N. (2013) · Reproductive Sciences · doi:10.1177/1933719113477495 · Cited by 154 · see citing works
Vigano, P., Corti, L., & Berlanda, N. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.08.030 · Cited by 103 · see citing works
Exacoustos, C., Lauriola, I., Lazzeri, L., De Felice, G., & Zupi, E. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.06.024 · Cited by 100 · see citing works
Nirgianakis, K., Gasparri, M. L., Radan, A.-P., Villiger, A., McKinnon, B., Mosimann, B., Papadia, A., & Mueller, M. D. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.04.036 · Cited by 70 · see citing works
Treatment of infertility associated with deep endometriosis: definition of therapeutic balances
Somigliana, E., & Garcia-Velasco, J. A. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.08.003 · Cited by 66 · see citing works
A stepped-care approach to symptomatic endometriosis management: A participatory research initiative
Vercellini, P., Donati, A., Ottolini, F., Frassineti, A., Fiorini, J., Nebuloni, V., Frattaruolo, M. P., Roberto, A., Mosconi, P., & Somigliana, E. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.01.037 · Cited by 64 · see citing works
Self-citationNew adverse obstetrics outcomes associated with endometriosis: A retrospective cohort study
Mannini, L., Sorbi, F., Noci, I., Ghizzoni, V., Perelli, F., Di Tommaso, M., Mattei, A., & Fambrini, M. (2017) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-016-4222-7 · Cited by 47 · see citing works
Maternal and neonatal outcomes in women with colorectal endometriosis
Thomin, A., Belghiti, J., David, C., Marty, O., Bornes, M., Ballester, M., Roman, H., & Daraï, E. (2018) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14221 · Cited by 39 · see citing works
Management of endometriosis: Toward value-based, cost-effective, affordable care
Vercellini, P., Facchin, F., Buggio, L., Barbara, G., Berlanda, N., Frattaruolo, M. P., & Somigliana, E. (2018) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2017.07.011 · Cited by 36 · see citing works
Self-citationVercellini, P., Somigliana, E., Cortinovis, I., Bracco, B., de Braud, L., Dridi, D., & Milani, S. (2015) · BMC Women's Health · doi:10.1186/s12905-015-0248-4 · Cited by 22 · see citing works
Self-citationVercellini, P., Frattaruolo, M., Barbara, G., Buggio, L., & Somigliana, E. (2018) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14789 · Cited by 15 · see citing works
Self-citationPlacenta previa with posterior extrauterine adhesion: clinical features and management practice
Nagase, Y., Matsuzaki, S., Endo, M., Hara, T., Okada, A., Mimura, K., Hiramatsu, K., Kakigano, A., Nakatsuka, E., Miyake, T., et al. (2021) · BMC Surgery · doi:10.1186/s12893-020-01027-9 · Cited by 14 · see citing works
- Authors
- Vercellini, P., Parazzini, F., Pietropaolo, G., Cipriani, S., Frattaruolo, M., & Fedele, L.
- Affiliations
- University of Milan (IT)
- Corresponding author
- Vercellini, P
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 2012-08-20
- Volume
- 119
- Issue
- 12
- Pages
- 1538-1543
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W1493411262
- Cited by
- 134
- References
- 10
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 6 · 2023: 3 · 2022: 15 · 2021: 19 · 2020: 16 · 2019: 3 · 2018: 7 · 2017: 14 · 2016: 15 · 2015: 12 · 2014: 10 · 2013: 3 · 2012: 1
- FWCI
- 9.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Università degli Studi di Milano
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- endometriosis, pregnancy outcomes, peritoneal endometriosis, endometrioma, rectovaginal endometriosis, miscarriage, ectopic pregnancy, preterm birth, placenta previa, gestational hypertension, preeclampsia, placental abruption, endometriosis surgery
- MeSH terms
- Adult, Endometriosis, Female, Follow-Up Studies, Humans, Ovarian Neoplasms, Peritoneal Neoplasms, Laparoscopy, Placenta Previa, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Rectal Neoplasms, Retrospective Studies, Vaginal Neoplasms, Cohort Studies, Incidence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
