An increase in religiousness/spirituality occurs after HIV diagnosis and predicts slower disease progression over 4 years in people with HIV
Open accessAbstract
Background Most studies on religion/spirituality predicting health outcomes have been limited to church attendance as a predictor and have focused on healthy people. However, confronting a major medical crisis may be a time when people turn to the sacred.Objective The purpose of this study was to determine the extent to which changes in spirituality/religiousness occur after HIV diagnosis and whether changes predict disease progression.Design/participants This longitudinal study examined the relationship between changes in spirituality/religiousness from before with after the diagnosis of HIV, and disease progression (CD4 and viral load [VL] every 6 months) over 4 years in 100 people with HIV. Measures included change in religiousness/spirituality after diagnosis of HIV, religiousness/spirituality at various times in one's life, church attendance, depression, hopelessness, optimism, coping (avoidant, proactive), social support, CD4/VL, and health behaviors.Results Forty-five percent of the sample showed an increase in religiousness/spirituality after the diagnosis of HIV, 42% remained the same, and 13% decreased. People reporting an increase in spirituality/religiousness after the diagnosis had significantly greater preservation of CD4 cells over the 4-year period, as well as significantly better control of VL. Results were independent of (i.e., held even after controlling for) church attendance and initial disease status (CD4/VL), medication at every time point, age, gender, race, education, health behaviors (adherence, risky sex, alcohol, cocaine), depression, hopelessness, optimism, coping (avoidant, proactive), and social support.Conclusions There is an increase in spirituality/religiousness after HIV diagnosis, and this increase predicts slower disease progression; medical personnel should be aware of its potential importance.
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Of the 14 highest-quality immune function studies, 10 (71%) reported significant positive associations or increased immune functions in response to an R/S intervention.
“Of the 14 studies with the highest quality ratings, 10 (71%) reported significant positive associations [437–443] or increased immune functions in response to a R/S intervention [444–447].”
From Religion, Spirituality, and Health: The Research and Clinical Implications (2012) · cites this paper as [446]
Of the 14 highest-quality cognitive function studies, eight (57%) reported positive relationships and three (21%) reported negative relationships with cognitive function.
“Of the 14 studies with the highest quality ratings, eight (57%) reported positive relationships [423–430] and three (21%) reported negative relationships with cognitive function [431–433].”
From Religion, Spirituality, and Health: The Research and Clinical Implications (2012) · cites this paper as [431]
The cited paper’s Discussion tables examine spirituality and HIV disease progression using CD4 counts and viral load, not cognitive function. Searches for cognitive-function relationships and the reported 14-study breakdown found no passage addressing either; the paper therefore cannot verify the negative-relationship count for which it is cited. (LLM, conf=0.76)
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Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
Hierarchical Linear Models: Applications and Data Analysis Methods.
Longford, N. T., Bryk, A. S., & Raudenbush, S. W. (1993) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2075823 · Cited by 18,768 · see citing works
Hierarchical Linear Models: Applications and Data Analysis Methods
Davidian, M. (2003) · Journal of the American Statistical Association · doi:10.1198/jasa.2003.s288 · Cited by 13,820 · see citing works
Assessing coping strategies: A theoretically based approach.
Carver, C. S., Scheier, M. F., & Weintraub, J. K. (1989) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.56.2.267 · Cited by 11,682 · see citing works
Assessing coping strategies: A theoretically based approach.
Carver, C. S., Scheier, M. F., & Weintraub, J. K. (1989) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.56.2.267 · Cited by 11,507 · see citing works
Scheier, M. F., Carver, C. S., & Bridges, M. W. (1994) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.67.6.1063 · Cited by 7,456 · see citing works
Optimism, coping, and health: Assessment and implications of generalized outcome expectancies.
Scheier, M. F., & Carver, C. S. (1985) · Health Psychology · doi:10.1037/0278-6133.4.3.219 · Cited by 6,690 · see citing works
The measurement of pessimism: the hopelessness scale
Beck, A. T., Weissman, A., Lester, D., & Trexler, L. (1974) · Journal of Consulting and Clinical Psychology · doi:10.1037/h0037562 · Cited by 5,494 · see citing works
Psychological stress and the human immune system: a meta-analytic study of 30 Years of inquiry
Segerstrom, S. C., & Miller, G. E. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.4.601 · Cited by 3,334 · see citing works
Stress and Health: Psychological, Behavioral, and Biological Determinants
Schneiderman, N., Ironson, G., & Siegel, S. D. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.144141 · Cited by 2,252 · see citing works
Self-citationHill, P. C., & Pargament, K. I. (2003) · American Psychologist · doi:10.1037/0003-066x.58.1.64 · Cited by 1,948 · see citing works
Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., Wu, A. W., & PATIENT CARE COMMITTEE & ADHERENCE (2000) · AIDS Care · doi:10.1080/09540120050042891 · Cited by 1,428 · see citing works
Religion and spirituality: Linkages to physical health.
Powell, L. H., Shahabi, L., & Thoresen, C. E. (2003) · American Psychologist · doi:10.1037/0003-066x.58.1.36 · Cited by 1,093 · see citing works
Religious involvement and mortality: A meta-analytic review.
McCullough, M. E., Hoyt, W. T., Larson, D. B., Koenig, H. G., & Thoresen, C. E. (2000) · Health Psychology · doi:10.1037/0278-6133.19.3.211 · Cited by 1,088 · see citing works
Hierarchical linear models: Applications and data analysis methods
Rumberger, R. W. (1997) · Economics of Education Review · doi:10.1016/s0272-7757(97)80188-4 · Cited by 974 · see citing works
Pargament, K. I., Koenig, H. G., Tarakeshwar, N., & Hahn, J. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.15.1881 · Cited by 759 · see citing works
Attachment, Evolution, and the Psychology of Religion
Kirkpatrick, L. A. (2004) · Choice Reviews Online · doi:10.5860/choice.43-0631 · Cited by 757 · see citing works
A Short Social Support Measure for Patients Recovering From Myocardial Infarction
Mitchell, P. H., Powell, L. H., Blumenthal, J. A., Norten, J., Ironson, G. H., Pitula, C. R., Froelicher, E. S., Czajkowski, S. M., Youngblood, M., Huber, M., et al. (2003) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200311000-00001 · Cited by 577 · see citing works
Self-citationIronson, G. H., O’Cleirigh, C. M., FLETCHER, M. A., Laurenceau, J., Balbin, E., Klimas, N. G., Schneiderman, N., & Solomon, G. F. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000188569.58998.c8 · Cited by 357 · see citing works
Self-citationSpirituality and religion in patients with HIV/AIDS
Cotton, S., Puchalski, C. M., Sherman, S. N., Mrus, J. M., Peterman, A. H., Feinberg, J., Pargäment, K. I., Justice, A. C., Leonard, A. C., & Tsevat, J. (2006) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2006.00642.x · Cited by 354 · see citing works
Ironson, G., Solomon, G. F., Balbin, E. G., O’Cleirigh, C., George, A., Kumar, M., Larson, D., & Woods, T. E. (2002) · Annals of Behavioral Medicine · doi:10.1207/s15324796abm2401_05 · Cited by 337 · see citing works
Self-citationLESERMAN, J., PETITTO, J. M., GU, H., GAYNES, B. N., BARROSO, J., GOLDEN, R. N., PERKINS, D. O., FOLDS, J. D., & EVANS, D. L. (2002) · Psychological Medicine · doi:10.1017/s0033291702005949 · Cited by 311 · see citing works
Cole, S. W., Korin, Y. D., Fahey, J. L., & Zack, J. A. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.2.610 · Cited by 228 · see citing works
Kristeller, J. L., Rhodes, M., Cripe, L. D., & Sheets, V. (2005) · The International Journal of Psychiatry in Medicine · doi:10.2190/8ae4-f01c-60m0-85c8 · Cited by 177 · see citing works
Ironson, G. H., Friedman, A. L., Klimas, N. G., Antoni, M. H., FLETCHER, M. A., LaPerriere, A. R., Simoneau, J., & Schneiderman, N. (1994) · International Journal of Behavioral Medicine · doi:10.1207/s15327558ijbm0101_6 · Cited by 168 · see citing works
Self-citationIronson, G. H., Balbin, E., Stuetzle, R., FLETCHER, M. A., O’Cleirigh, C. M., Laurenceau, J., Schneiderman, N., & Solomon, G. F. (2005) · International Journal of Behavioral Medicine · doi:10.1207/s15327558ijbm1202_6 · Cited by 149 · see citing works
Self-citationReligion and Spirituality in the Face of Illness
Woods, T. E., & Ironson, G. H. (1999) · Journal of Health Psychology · doi:10.1177/135910539900400308 · Cited by 127 · see citing works
Self-citationThe Will To Live among HIV-Infected Patients
Tsevat, J., Sherman, S. N., McElwee, J. A., Mandell, K. L., Simbartl, L. A., Sonnenberg, F. A., & Fowler, F. J. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-131-3-199908030-00006 · Cited by 121 · see citing works
Simoni, J. M., & Ortiz, M. Z. (2003) · Cultural Diversity & Ethnic Minority Psychology · doi:10.1037/1099-9809.9.1.3 · Cited by 96 · see citing works
Ironson, G. H., Balbin, E., Solomon, G. F., Fahey, J. L., Klimas, N. G., Schneiderman, N., & FLETCHER, M. A. (2001) · AIDS · doi:10.1097/00002030-200111090-00001 · Cited by 60 · see citing works
Self-citationChanges in religiousness and spirituality attributed to HIV/AIDS
Cotton, S., Tsevat, J., Szaflarski, M., Kudel, I., Sherman, S. N., Feinberg, J., Leonard, A. C., & Holmes, W. C. (2006) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2006.00641.x · Cited by 56 · see citing works
Psychosocial outcomes after an MI: An evaluation of two approaches to rehabilitation
O'Rourke, A., & Hampson, S. E. (1999) · Psychology Health & Medicine · doi:10.1080/135485099106144 · Cited by 32 · see citing works
Religio‐Biography, Coping, and Meaning‐Making Among Persons with HIV/AIDS
Jacobson, C. J., Luckhaupt, S. E., DeLaney, S. C., & Tsevat, J. (2006) · Journal for the Scientific Study of Religion · doi:10.1111/j.1468-5906.2006.00004.x · Cited by 32 · see citing works
Psychoneuroimmunology and the faith factor.
Hg, K. (2001) · PubMed · Cited by 29 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- Ironson G, O'Cleirigh C, Fletcher MA, et al. Psychosocial factors pre- dict CD4 and viral load change in men and women in the era of HAART. Psychosomat Med. 2005;67:1013-21.
- Ironson G, Kremer H, Ironson D. Spirituality, spiritual experiences, and spiritual transformations in the face of HIV. In: Koss-Chiono J, Hefner P, eds. Spiritual Transformation and Healing: Anthropological, Religious, Neuroscientific, and Clinical Perspectives. Walnut Creek, CA: Altamira Press; 2006:241.
- Cotton S, Tsevat J, Szaflarski M, et al. Religious and spiritual experi- ences of people with HIV. J Gen Intern Med. 2006;21:s5-13.
- Psychiatric Annals Special Issue: Spirituality in Psychiatric Practice: Guidelines for assessing and managing religious and spiritual issues. March 2006; 137-204.
Cited by
Sorted by citations
Religion, Spirituality, and Health: The Research and Clinical Implications
Koenig, H. G. (2012) · ISRN Psychiatry · doi:10.5402/2012/278730 · Cited by 2,423 · see citing works
“%) reported significant inverse associations with infection/viral load [440, 441, 449–454].”
BackgroundTrevino, K. M., Pargament, K. I., Cotton, S., Leonard, A. C., Hahn, J., Caprini-Faigin, C. A., & Tsevat, J. (2010) · AIDS and Behavior · doi:10.1007/s10461-007-9332-6 · Cited by 273 · see citing works
Religiousness and Mental Health: Systematic Review Study
AbdAleati, N. S., Mohd Zaharim, N., & Mydin, Y. O. (2016) · Journal of Religion and Health · doi:10.1007/s10943-014-9896-1 · Cited by 158 · see citing works
Spiritual Well-Being, Depressive Symptoms, and Immune Status Among Women Living with HIV/AIDS
Dalmida, S. G., Holstad, M. M., Diiorio, C., & Laderman, G. (2009) · Women & Health · doi:10.1080/03630240902915036 · Cited by 132 · see citing works
Blumenthal, J. A., Babyak, M. A., Ironson, G., Thoresen, C., Powell, L., Czajkowski, S., Burg, M., Keefe, F. J., Steffen, P., & Catellier, D. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3180cab76c · Cited by 119 · see citing works
Self-citationSpiritual Transformation, Psychological Well-Being, Health, and Survival in People with HIV
Ironson, G., & Kremer, H. (2009) · The International Journal of Psychiatry in Medicine · doi:10.2190/pm.39.3.d · Cited by 110 · see citing works
Self-citationExtending Religion-Health Research to Secular Minorities: Issues and Concerns
Hwang, K., Hammer, J. H., & Cragun, R. T. (2011) · Journal of Religion and Health · doi:10.1007/s10943-009-9296-0 · Cited by 92 · see citing works
Bormann, J. E., Aschbacher, K., Wetherell, J. L., Roesch, S., & Redwine, L. (2009) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2008.09.017 · Cited by 91 · see citing works
Schnell, T., Fuchs, D., & Hefti, R. (2020) · Journal of Religion and Health · doi:10.1007/s10943-020-01008-5 · Cited by 69 · see citing works
- Authors
- Ironson, G., Stuetzle, R., & Fletcher, M. A.
- Affiliations
- University of Miami (US)
- Corresponding author
- Ironson, Gail
- ORCID
- Ironson, Gail
- Venue
- Journal of General Internal Medicine
- Published
- 2006-12
- Volume
- 21
- Issue
- S5
- Pages
- S62-S68
- ISSN
- 0884-8734 (ISSN-L)
- 1525-1497
- PMC
- PMC1924782
- OpenAlex
- W2151484055
- Cited by
- 344
- References
- 35
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 1 · 2023: 50 · 2022: 9 · 2021: 6 · 2020: 62 · 2019: 19 · 2018: 9 · 2017: 8 · 2016: 16 · 2015: 17 · 2014: 24 · 2013: 13 · 2012: 20
- FWCI
- 13.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of General Internal Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- NSUWorks (Nova Southeastern University) (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH066697, R01 MH53791, R01MH053791)
- Topics
- Social Sciences › Health › Religion, Spirituality, and Psychology
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Social Sciences › Demography › Workplace Spirituality and Leadership
- Keywords
- HIV, religiosity, spirituality, HIV diagnosis, disease progression, CD4 count, viral load, coping, church attendance, depression, hopelessness, optimism, social support, coping styles
- MeSH terms
- Adaptation, Psychological, Florida, Humans, Life Change Events, Longitudinal Studies, Religion and Psychology, Risk-Taking, Social Support, HIV Infections, Causality, Disease Progression
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