Cited by 106Substance Abuse Treatment and OutcomesAlcohol Consumption and Health EffectsGambling Behavior and Treatments

Interactive Effects of Cumulative Stress and Impulsivity on Alcohol Consumption

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Helen C., Fox, Keri L., Bergquist, Peihua, Gu, Rajita, Sinha·2010·Alcoholism: Clinical and Experimental Research

Abstract

Background: Alcohol addiction may reflect adaptations to stress, reward, and regulatory brain systems. While extensive research has identified both stress and impulsivity as independent risk factors for drinking, few studies have assessed the interactive relationship between stress and impulsivity in terms of hazardous drinking within a community sample of regular drinkers. Methods: One hundred and thirty regular drinkers (56M/74F) from the local community were assessed for hazardous and harmful patterns of alcohol consumption using the Alcohol Use Disorders Identification Test (AUDIT). All participants were also administered the Barratt Impulsiveness Scale (BIS‐11) as a measure of trait impulsivity and the Cumulative Stress/Adversity Checklist (CSC) as a comprehensive measure of cumulative adverse life events. Standard multiple regression models were used to ascertain the independent and interactive nature of both overall stress and impulsivity as well as specific types of stress and impulsivity on hazardous and harmful drinking. Results: Recent life stress, cumulative traumatic stress, overall impulsivity, and nonplanning‐related impulsivity as well as cognitive and motor‐related impulsivity were all independently predictive of AUDIT scores. However, the interaction between cumulative stress and total impulsivity scores accounted for a significant amount of the variance, indicating that a high to moderate number of adverse events and a high trait impulsivity rating interacted to affect greater AUDIT scores. The subscale of cumulative life trauma accounted for the most variance in AUDIT scores among the stress and impulsivity subscales. Conclusions: Findings highlight the interactive relationship between stress and impulsivity with regard to hazardous drinking. The specific importance of cumulative traumatic stress as a marker for problem drinking is also discussed.

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Crossref · 10.1111/j.1530-0277.2010.01221.x

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  • These impairments, marked by impulsivity under stress, are associated with substance abuse, other addictive behaviors, and eating disturbances.

    “These impairments, marked by impulsivity in the face of stress, for example, are in turn associated with substance abuse, other addictive behaviors, and eating disturbances (Dawe & Loxton, 2004; Fox, Bergquist, Gu, & Sinha, 2010; Hyman, Malenka, & Nestler, 2006)”

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Research works printed but not linked: 3

  1. First MB Spitzer RL Gibbon M Williams JBW 1997 Structured Clinical Interview for the DSM-IV Axis I Disorders – Patient Edition (SCID-I/P Version 2.0, 4/97 revision) New York State Psychiatric Institute New York
  2. Fox HC Sinha R 2009 Stress, Neuroendcrine Response and Addiction in Women, in Women and Addiction: A Comprehensive Textbook Brady K Greenfield S 65 83 Gulidford Press NY
  3. Marlatt GA Gordon JR 1985 Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors Guilford Press New York

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Authors
Helen C., F., Keri L., B., Peihua, G., & Rajita, S.
Affiliations
Yale University (US)
Venue
Alcoholism: Clinical and Experimental Research
Publisher
Wiley
Published
2010-07-21
Volume
34
Issue
8
Pages
1376-1385
ISSN
  • 0145-6008 (ISSN-L)
  • 1530-0277
OpenAlex
W2099103863
Cited by
106
References
93
Citations by year
2026: 3 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 11 · 2021: 8 · 2020: 10 · 2019: 5 · 2018: 9 · 2017: 5 · 2016: 6 · 2015: 8 · 2014: 8 · 2013: 4 · 2012: 9
FWCI
5.08
Type
journal article
Language
en
Open access
Locations
  • Alcoholism Clinical and Experimental Research (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health
  • National Institute on Alcohol Abuse and Alcoholism (R01AA013892)
  • National Institute on Drug Abuse (PLI-DA024859, PL1DA024859)
  • National Institute of Dental and Craniofacial Research (UL1DE019586)
  • Common Fund
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
Keywords
cumulative stress, impulsivity, alcohol consumption, hazardous drinking, life events, trait impulsivity, problem drinking, cumulative adversity
MeSH terms
Adult, Alcohol Drinking, Chronic Disease, Female, Humans, Impulsive Behavior, Interviews as Topic, Male, Stress, Psychological, Alcohol-Related Disorders, Young Adult

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