Depression in chronic pain patients: Prevalence and measurement
Abstract
This study aimed to: (1) determine prevalence of depression in patients referred to specialist pain services using the Structured Clinical Interview (SCID) diagnostic interview, (2) compare results on the Beck Depression Inventory II (BDI-II) with the SCID to determine the utility of the BDI-II as a screening tool in this population. Thirty-six participants were recruited, mainly women, with a mean age = 47.83 years (standard deviation = 12.85 years), who were heterogeneous with regard to their pain. All completed the BDI-II and SCID. The SCID diagnosed 26 (72%) cases of depression. BDI-II scores showed 31 (86%) that reported at least mild depression. Agreement between BDI-II scores over threshold for mild depression and SCID diagnosis were assessed by Cohen's kappa (= 0.6). ROC analysis for BDI-II scores against SCID diagnosis gave a large area under the curve (0.97, 95% confidence interval 0.93 to 1.02), suggesting BDI-II is an excellent screen for this population, although the curve was unusual in that sensitivity was high even when the false positive rate was zero. ROC analysis suggested 22 or above as an optimum cut-off score for depression on the BDI-II-higher than for a general population sample. It has been suggested that the BDI overestimates incidence of depression in pain patients, but this study confirmed through diagnostic interview the very high incidence of depression in this population. It is therefore questionable whether there is value in screening referrals…
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When self-report measures of depression are used, the prevalence of depression in individuals experiencing chronic pain is as high as 86%.
“When self-report measures of depression are used, the prevalence of depression in individuals experiencing chronic pain is as high as 86%”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Poole, White, Blake, Murphy, & Bramwell, 2009
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- Authors
- Poole, H., White, S., Blake, C., Murphy, P., & Bramwell, R.
- Affiliations
- Liverpool John Moores University (GB)
- Lancashire Care NHS Foundation Trust (GB)
- University of Liverpool (GB)
- Walton Centre (GB)
- University of Chester (GB)
- Corresponding author
- Poole, Helen
- Venue
- Pain Practice
- Publisher
- Wiley
- Published
- 2009-04-27
- Volume
- 9
- Issue
- 3
- Pages
- 173-180
- ISSN
- 1530-7085 (ISSN-L)
- 1533-2500
- OpenAlex
- W2003521553
- Cited by
- 129
- References
- 7
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 5 · 2023: 3 · 2022: 5 · 2021: 10 · 2020: 10 · 2019: 12 · 2018: 9 · 2017: 13 · 2016: 13 · 2015: 12 · 2014: 8 · 2013: 6 · 2012: 6
- FWCI
- 3.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pain Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- depression, chronic pain, prevalence, Beck Depression Inventory-II, severe combined immunodeficiency, depression screening, cut-off values, diagnostic agreement, pain clinic patients
- MeSH terms
- Adult, Aged, Anxiety Disorders, Cross-Sectional Studies, Depressive Disorder, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Pain Measurement, Pain, Intractable, Intractable Pain, Predictive Value of Tests, Surveys and Questionnaires, Self-Assessment, Reproducibility of Results, Cohort Studies, Comorbidity, Prevalence, Marital Status, Age of Onset, Sex Distribution
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