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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

REVIEW ARTICLE: Th1/Th2/Th17 and Regulatory T‐Cell Paradigm in Pregnancy

Open access
Saito, Shigeru, Nakashima, Akitoshi, Shima, Tomoko, Ito, Mika·2010·American Journal of Reproductive Immunology
DOI 10.1111/j.1600-0897.2010.00852.x
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Abstract

Citation Saito S, Nakashima A, Shima T, Ito M. Th1/Th2/Th17 and regulatory T‐cell paradigm in pregnancy. Am J Reprod Immunol 2010 T‐helper (Th) cells play a central role in modulating immune responses. The Th1/Th2 paradigm has now developed into the new Th1/Th2/Th17 paradigm. In addition to effector cells, Th cells are regulated by regulatory T (Treg) cells. Their capacity to produce cytokines is suppressed by immunoregulatory cytokines such as transforming growth factor (TGF)‐β and interleukin (IL)‐10 or by cell‐to‐cell interaction. Here, we will review the immunological environment in normal pregnancy and complicated pregnancy, such as implantation failure, abortion, preterm labor, and preeclampsia from the viewpoint of the new Th1/Th2/Th17 and Treg paradigms.

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Metadata

Authors
Saito, S., Nakashima, A., Shima, T., & Ito, M.
Venue
American Journal of Reproductive Immunology
Publisher
Wiley
Published
2010-05-10
Volume
63
Issue
6
Pages
601-610
ISSN
  • 0271-7352 (ISSN-L)
  • 1046-7408
  • 1600-0897
DOI
10.1111/j.1600-0897.2010.00852.x
OpenAlex
W1498159349
Cited by
1,109
References
3
FWCI
16.86
Type
journal article
Language
en
Open access
bronze
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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CoChat. (2026). Citation check: REVIEW ARTICLE: Th1/Th2/Th17 and Regulatory T‐Cell Paradigm in Pregnancy. https://app.cochat.ai/papers/10.1111/j.1600-0897.2010.00852.x
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Saito, S., Nakashima, A., Shima, T., & Ito, M. (2010). REVIEW ARTICLE: Th1/Th2/Th17 and Regulatory T‐Cell Paradigm in Pregnancy. American Journal of Reproductive Immunology. https://doi.org/10.1111/j.1600-0897.2010.00852.x

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.