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Glycobiology of immune responses
Open accessAbstract
Unlike their protein “roommates” and their nucleic acid “cousins," carbohydrates remain an enigmatic arm of biology. The central reason for the difficulty in fully understanding how carbohydrate structure and biological function are tied is the nontemplate nature of their synthesis and the resulting heterogeneity. The goal of this collection of expert reviews is to highlight what is known about how carbohydrates and their binding partners—the microbial (non‐self), tumor (altered‐self), and host (self)—cooperate within the immune system, while also identifying areas of opportunity to those willing to take up the challenge of understanding more about how carbohydrates influence immune responses. In the end, these reviews will serve as specific examples of how carbohydrates are as integral to biology as are proteins, nucleic acids, and lipids. Here, we attempt to summarize general concepts on glycans and glycan‐binding proteins (mainly C‐type lectins, siglecs, and galectins) and their contributions to the biology of immune responses in physiologic and pathologic settings.
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Cites
Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation
Kaneko, Y., Nimmerjahn, F., & Ravetch, J. V. (2006) · Science · doi:10.1126/science.1129594 · Cited by 1,754
Dectin-1: a signalling non-TLR pattern-recognition receptor
Brown, G. D. (2006) · Nature Reviews Immunology · doi:10.1038/nri1745 · Cited by 1,158
Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
Demetriou, M., Granovsky, M., Quaggin, S., & Dennis, J. W. (2001) · Nature · doi:10.1038/35055582 · Cited by 901
Candida albicans morphogenesis and host defence: discriminating invasion from colonization
Gow, N. A. R., van de Veerdonk, F. L., Brown, A. J. P., & Netea, M. G. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2711 · Cited by 888
C-type lectin receptors on dendritic cells and langerhans cells
Figdor, C. G., van Kooyk, Y., & Adema, G. J. (2002) · Nature Reviews Immunology · doi:10.1038/nri723 · Cited by 842
Toscano, M. A., Bianco, G. A., Ilarregui, J. M., Croci, D. O., Correale, J., Hernandez, J. D., Zwirner, N. W., Poirier, F., Riley, E. M., Baum, L. G., et al. (2007) · Nature Immunology · doi:10.1038/ni1482 · Cited by 653
Self-citationSelf- and nonself-recognition by C-type lectins on dendritic cells
Geijtenbeek, T. B. H., van Vliet, S. J., Engering, A., 't Hart, B. A., & van Kooyk, Y. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104558 · Cited by 503
Brewer, C. (2002) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(02)00364-0 · Cited by 435
Galectin–glycan lattices regulate cell-surface glycoprotein organization and signalling
Garner, O. B., & Baum, L. G. (2008) · Biochemical Society Transactions · doi:10.1042/bst0361472 · Cited by 226
Paul, S. P., Taylor, L. S., Stansbury, E. K., & McVicar, D. W. (2000) · Blood · doi:10.1182/blood.v96.2.483.014k40_483_490 · Cited by 202
Research works printed but not linked: 103
- 10.1177/00220345870660020901 · DOI · Paper page
- Brockhausen I., 2009, Essentials of Glycobiology, 115
- Stanley P., 2009, Essentials of Glycobiology, 101
- 10.1038/nrmicro2383 · DOI · Paper page
- 10.1097/MOP.0b013e32834cd693 · DOI
- 10.1023/A:1010581613821 · doi:10.1023/a:1010581613821
- 10.1093/glycob/11.12.1051 · DOI
- 10.1016/j.cell.2006.08.019 · DOI · Paper page
- 10.1016/j.carres.2009.04.031 · DOI · Paper page
- 10.1074/jbc.M111.242677 · DOI
- 10.1016/j.ceb.2011.05.001 · DOI · Paper page
- 10.1016/S1074-7613(01)00092-9 · DOI
- 10.1073/pnas.1001772107 · doi:10.1073/pnas.1001772107
- 10.1016/S0065-3527(06)68005-6 · DOI · Paper page
- 10.1073/pnas.0407902101 · DOI · Paper page
- 10.1093/glycob/cwj048 · DOI · Paper page
- 10.1084/jem.20100508 · DOI
- 10.1007/s10719-009-9239-8 · DOI
- 10.1016/j.cellsig.2009.09.038 · DOI · Paper page
- 10.1038/nri1182 · DOI · Paper page
- 10.1002/eji.1830261250 · doi:10.1002/eji.1830261250
- 10.4049/jimmunol.1003005 · DOI
- 10.1111/j.1749-6632.2009.05131.x · DOI · Paper page
- 10.1038/nature10134 · DOI · Paper page
- 10.1159/000228160 · DOI
- 10.1016/j.ceb.2003.08.002 · DOI · Paper page
- 10.1038/ni1442 · DOI · Paper page
- 10.2217/imt.09.44 · DOI
- 10.1038/35107092 · DOI · Paper page
- 10.1128/JB.01155-06 · DOI · Paper page
- 10.1038/ni.f.203 · DOI · Paper page
- 10.1016/S0959-440X(99)00009-3 · DOI · Paper page
- 10.1016/S0008-6215(00)90340-9 · DOI
- 10.1016/j.it.2007.10.010 · DOI · Paper page
- 10.1111/j.1742-4658.2005.05031.x · DOI · Paper page
- 10.4049/jimmunol.168.5.2118 · DOI · Paper page
- 10.1016/j.coi.2010.11.011 · DOI
- 10.1182/blood-2010-02-268425 · DOI
- 10.1016/j.molimm.2009.09.026 · DOI
- 10.4049/jimmunol.180.6.3647 · DOI · Paper page
- 10.1073/pnas.0610383104 · DOI · Paper page
- 10.1172/JCI34584 · DOI · Paper page
- 10.1016/j.immuni.2011.05.001 · DOI · Paper page
- 10.1093/intimm/13.10.1283 · DOI · Paper page
- 10.1016/j.molimm.2008.11.021 · DOI
- 10.1074/jbc.M110.113613 · DOI
- 10.1002/ijc.23101 · DOI
- 10.1016/j.immuni.2007.03.012 · DOI · Paper page
- 10.1038/ni.1778 · DOI · Paper page
- 10.1038/nri2569 · DOI · Paper page
- 10.1093/glycob/cwp186 · DOI · Paper page
- 10.1158/0008-5472.CAN-04-4140 · DOI · Paper page
- 10.1007/s00262-006-0274-z · DOI
- 10.1016/S0092-8674(00)80694-7 · DOI · Paper page
- 10.1038/nm1541 · DOI · Paper page
- 10.1182/blood-2008-01-136473 · DOI · Paper page
- 10.1111/j.1600-065X.2009.00786.x · DOI
- 10.1084/jem.20041276 · DOI · Paper page
- 10.1038/ni1390 · DOI · Paper page
- 10.1038/nri2056 · DOI · Paper page
- 10.1016/j.tips.2009.02.005 · DOI · Paper page
- 10.1021/cr000407m · DOI · Paper page
- 10.1016/j.it.2006.04.005 · DOI
- 10.1038/nri2536 · DOI · Paper page
- 10.1021/bi201121m · DOI · Paper page
- 10.1111/j.1600-065X.2009.00790.x · DOI · Paper page
- 10.1038/ni1271 · DOI · Paper page
- 10.1016/S0076-6879(10)80011-4 · DOI
- 10.4049/jimmunol.182.2.1167 · DOI · Paper page
- 10.1002/art.30118 · DOI
- 10.1038/nrd1751 · DOI · Paper page
- 10.1111/j.1600-065X.2009.00795.x · DOI · Paper page
- 10.1080/08916930601061470 · DOI
- 10.1074/jbc.M111.277814 · DOI
- 10.1016/j.immuni.2007.06.008 · DOI · Paper page
- 10.1046/j.1523-1755.2001.0590031077.x · doi:10.1046/j.1523-1755.2001.0590031077.x · Paper page
- 10.1093/glycob/cwn072 · DOI · Paper page
- 10.1038/4371252a · DOI · Paper page
- 10.1038/ni.1772 · DOI · Paper page
- 10.2353/ajpath.2007.060335 · doi:10.2353/ajpath.2007.060335
- 10.1038/nm.2201 · DOI
- 10.4049/jimmunol.0902711 · DOI
- Saeland E., 2011, Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients, Int. J. Cancer
- 10.1002/eji.200939748 · DOI
- 10.1182/blood-2010-01-264960 · DOI · Paper page
- 10.1002/eji.201040762 · DOI
- 10.4049/jimmunol.176.11.6770 · DOI · Paper page
- 10.1182/blood-2008-05-155176 · DOI · Paper page
- 10.1358/dnp.2010.23.9.1437246 · doi:10.1358/dnp.2010.23.9.1437246
- 10.3390/cancers3033169 · DOI
- 10.1007/978-1-60761-869-0_23 · DOI
- 10.1016/S1535-6108(04)00024-8 · DOI · Paper page
- 10.1038/jid.2011.335 · DOI
- 10.1073/pnas.0706017104 · DOI · Paper page
- 10.1158/0008-5472.CAN-10-4157 · DOI
- 10.4049/jimmunol.1002940 · DOI
- Tang D., 2011, High expression of galectin‐1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer, Int. J. Cancer.
- Soldati R., 2011, Neuroblastoma triggers an immunoevasive program involving galectin‐1‐dependent modulation of T cell and dendritic cell compartments, Int. J. Cancer.
- 10.4049/jimmunol.0903275 · DOI · Paper page
- 10.1158/0008-5472.CAN-10-0761 · DOI · Paper page
- 10.1038/emboj.2011.215 · DOI · Paper page
- 10.1002/eji.200323693 · DOI · Paper page
- 10.1016/j.bbrc.2010.10.079 · DOI
Cited by
Hallmarks of glycosylation in cancer
Munkley, J., & Elliott, D. J. (2016) · Oncotarget · doi:10.18632/oncotarget.8155 · Cited by 521
Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives
Jankowska, E. A., von Haehling, S., Anker, S. D., Macdougall, I. C., & Ponikowski, P. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs224 · Cited by 399
Glycopolymer probes of signal transduction
Kiessling, L. L., & Grim, J. C. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60097a · Cited by 335
The role of galectins in immunity and infection
Liu, F.-T., & Stowell, S. R. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-022-00829-7 · Cited by 313
Sweeten PAMPs: Role of sugar complexed PAMPs in innate immunity and vaccine biology
Mahla, R. S. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00248 · Cited by 239
Metadata
- Authors
- Rabinovich, G. A., van Kooyk, Y., & Cobb, B. A.
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2012-04
- Volume
- 1253
- Issue
- 1
- Pages
- 1-15
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2142574184
- Cited by
- 279
- References
- 14
- FWCI
- 7.67
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.