Dynamic Brain Sources of Visual Evoked Responses
Abstract
It has been long debated whether averaged electrical responses recorded from the scalp result from stimulus-evoked brain events or stimulus-induced changes in ongoing brain dynamics. In a human visual selective attention task, we show that nontarget event-related potentials were mainly generated by partial stimulus-induced phase resetting of multiple electroencephalographic processes. Independent component analysis applied to the single-trial data identified at least eight classes of contributing components, including those producing central and lateral posterior alpha, left and right mu, and frontal midline theta rhythms. Scalp topographies of these components were consistent with their generation in compact cortical domains.
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The model does not account for negative BOLD responses or changes in spontaneous activity.
“However, this model fails to account for negative BOLD responses (153), or changes in spontaneous activity (154).”
From Electrophysiological source imaging: A noninvasive window to brain dynamics (2018) · cites this paper as [154]
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- Authors
- Makeig, S., Westerfield, M., Jung, T.-P., Enghoff, S., Townsend, J., Courchesne, E., & Sejnowski, T. J.
- Affiliations
- Howard Hughes Medical Institute (US)
- Computational Neurobiology Laboratory and
- Department of Neurosciences, School of Medicine; and
- Venue
- Science
- Published
- 2002-01-25
- Volume
- 295
- Issue
- 5555
- Pages
- 690-694
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2016479629
- Cited by
- 1,630
- References
- 29
- Citations by year
- 2026: 37 · 2025: 40 · 2024: 37 · 2023: 43 · 2022: 56 · 2021: 51 · 2020: 56 · 2019: 93 · 2018: 66 · 2017: 60 · 2016: 74 · 2015: 63 · 2014: 69 · 2013: 74 · 2012: 77
- FWCI
- 36.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01ns034155-03)
- National Institute of Mental Health (2-RO1-MH36840, R01MH036840)
- National Institute of Neurological Disorders and Stroke (1RO1-NS34155)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- visual evoked potentials, event-related potentials, visual selective attention, alpha rhythm, mu rhythm, theta oscillations, single-trial EEG, independent component analysis, cortical sources, scalp topography
- MeSH terms
- Adult, Alpha Rhythm, Attention, Brain, Brain Mapping, Data Interpretation, Statistical, Electroencephalography, Evoked Potentials, Visual, Humans, Mathematics, Photic Stimulation, Theta Rhythm
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