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Cited by 694

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Interfaces Between the Detection, Signaling, and Repair of DNA Damage

Rouse, John, Jackson, Stephen P.·2002·Science
DOI 10.1126/science.1074740
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Abstract

Left unrepaired, the myriad types of damage that can occur in genomic DNA pose a serious threat to the faithful transmission of the correct complement of genetic material. Defects in DNA damage signaling and repair result in genomic instability, a hallmark of cancer, and often cause lethality, underlining the importance of these processes in the cell and whole organism. The past decade has seen huge advances in our understanding of how the signal transduction pathways triggered by DNA damage radically alter cell behavior. In contrast, it is still unclear how primary DNA damage is detected and how this interfaces with signal transduction and DNA repair proteins.

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Citations

Cites

Show all 13 references

Research works printed but not linked: 40

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Metadata

Authors
Rouse, J., & Jackson, S. P.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
2002-07-26
Volume
297
Issue
5581
Pages
547-551
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.1074740
OpenAlex
W2102566010
Cited by
694
References
13
FWCI
19.65
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Interfaces Between the Detection, Signaling, and Repair of DNA Damage. https://app.cochat.ai/papers/10.1126/science.1074740
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Rouse, J., & Jackson, S. P. (2002). Interfaces Between the Detection, Signaling, and Repair of DNA Damage. Science. https://doi.org/10.1126/science.1074740

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.