Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

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Mechanism of activation of protein kinase B by insulin and IGF‐1.

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

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Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Sarbassov, D. D., Ali, S. M., Kim, D.-H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P., & Sabatini, D. M. (2004) · Current Biology · doi:10.1016/j.cub.2004.06.054 · Cited by 2,665

Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control

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Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

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Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

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The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins

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Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

Stephens, L., Anderson, K. E., Stokoe, D., Erdjument‐Bromage, H., Painter, G. F., Holmes, A. B., Gaffney, P. R. J., Reese, C. B., McCormick, F. P., Tempst, P., et al. (1998) · Science · doi:10.1126/science.279.5351.710 · Cited by 1,061

PTEN and GSK3β: key regulators of progression to androgen-independent prostate cancer

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Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer’s Disease

Mullins, R. J., Diehl, T. C., Chia, C. W., & Kapogiannis, D. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00118 · Cited by 227

Muscle-Specific Deletion of Rictor Impairs Insulin-Stimulated Glucose Transport and Enhances Basal Glycogen Synthase Activity

Kumar, A. T., Harris, T. E., Keller, S. R., Choi, K. M., Magnuson, M. A., & Lawrence, J. C. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01405-07 · Cited by 223

Cholesterol trafficking is required for mTOR activation in endothelial cells

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Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

Ehninger, D., & Silva, A. J. (2010) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2010.10.002 · Cited by 223

Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Liu, Q., Xu, C., Kirubakaran, S., Zhang, X., Hur, W., Liu, Y., Kwiatkowski, N. P., Wang, J., Westover, K. D., Gao, P., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-1702 · Cited by 219

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism

Fox, D. B., Garcia, N. M. G., McKinney, B. J., Lupo, R., Noteware, L. C., Newcomb, R., Liu, J., Locasale, J. W., Hirschey, M. D., & Alvarez, J. V. (2020) · Nature Metabolism · doi:10.1038/s42255-020-0191-z · Cited by 214

CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer

Burkhardt, L., Fuchs, S., Krohn, A., Masser, S., Mäder, M., Kluth, M., Bachmann, F., Huland, H., Steuber, T. P., Graefen, M., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-1342 · Cited by 218

MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells

Jones, R. G., & Pearce, E. J. (2017) · Immunity · doi:10.1016/j.immuni.2017.04.028 · Cited by 218

Regulation of mTORC2 Signaling

Fu, W., & Hall, M. N. (2020) · Genes · doi:10.3390/genes11091045 · Cited by 225

The amino acid sensitive TOR pathway from yeast to mammals

Dann, S. G., & Thomas, G. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.04.068 · Cited by 216

mTORC2 Regulates Neutrophil Chemotaxis in a cAMP- and RhoA-Dependent Fashion

Liu, L., Das, S., Losert, W., & Parent, C. A. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.11.004 · Cited by 208

Loss of the TOR Kinase Tor2 Mimics Nitrogen Starvation and Activates the Sexual Development Pathway in Fission Yeast

Matsuo, T., Otsubo, Y., Urano, J., Tamanoi, F., & Yamamoto, M. P. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01039-06 · Cited by 212

The Insulin-Like Growth Factor System in Cancer

Weroha, S. J., & Haluska, P. (2012) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2012.04.014 · Cited by 213

Role of PI3K-AKT-mTOR Pathway as a Pro-Survival Signaling and Resistance-Mediating Mechanism to Therapy of Prostate Cancer

Pungsrinont, T., Kallenbach, J., & Baniahmad, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222011088 · Cited by 218

Recent advances and limitations of mTOR inhibitors in the treatment of cancer

Ali, E. S., Mitra, K., Akter, S., Ramproshad, S., Mondal, B., Khan, I. N., Islam, M. T., Sharifi‐Rad, J., Călina, D. C., & Cho, W. C. S. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02706-8 · Cited by 228

Adiponectin Sensitizes Insulin Signaling by Reducing p70 S6 Kinase-mediated Serine Phosphorylation of IRS-1

Wang, C., Mao, X., Wang, L., Liu, M., Wetzel, M. D., Guan, K.-L., Dong, L. Q., & Liu, F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700098200 · Cited by 210

Intracellular signaling pathway regulation of myelination and remyelination in the CNS

Gaesser, J. M., & Fyffe-Maricich, S. L. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.03.008 · Cited by 217

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Carracedo, A., Ma, L., Teruya-Feldstein, J., Rojo, F., Salmena, L., Alimonti, A., Egia, A., Sasaki, A. T., Thomas, G., Kozma, S. C., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34739 · Cited by 1,381

Involvement of Akt in neurite outgrowth

Read, D. E., & Gorman, A. M. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0057-8 · Cited by 213

Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma

Zhou, Q., Lui, V. W. Y., & Yeo, W. (2011) · Future Oncology · doi:10.2217/fon.11.95 · Cited by 217

mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT

Gu, Y., de Albuquerque, C. P., Braas, D., Zhang, W., Villa, G. R., Bi, J., Ikegami, S., Masui, K., Gini, B., Yang, H., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.05.030 · Cited by 208

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

Hurov, K. E., Cotta-Ramusino, C., & Elledge, S. J. (2010) · Genes & Development · doi:10.1101/gad.1934210 · Cited by 210

Disruption of Tsc2 in pancreatic β cells induces β cell mass expansion and improved glucose tolerance in a TORC1-dependent manner

Rachdi, L., Balcázar, N., Osorio-Duque, F., Elghazi, L., Weiss, A., Gould, A. P., Chang-Chen, K. J., Gambello, M. J., & Bernal‐Mizrachi, E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803047105 · Cited by 217

Mammalian Target of Rapamycin: Discovery of Rapamycin Reveals a Signaling Pathway Important for Normal and Cancer Cell Growth

Gibbons, J. J., Abraham, R. T., & Yu, K. (2009) · Seminars in Oncology · doi:10.1053/j.seminoncol.2009.10.011 · Cited by 212

Evidence for Direct Activation of mTORC2 Kinase Activity by Phosphatidylinositol 3,4,5-Trisphosphate

Gan, X., Wang, J., Su, B., & Wu, D. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.195016 · Cited by 217

The Effect of Oxidative Stress-Induced Autophagy by Cadmium Exposure in Kidney, Liver, and Bone Damage, and Neurotoxicity

Ma, Y., Su, Q., Yue, C., Zou, H., Zhu, J., Zhao, H., Song, R., & Liu, Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113491 · Cited by 214

PIKKing on PKB: regulation of PKB activity by phosphorylation

Bozulic, L., & Hemmings, B. A. (2009) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2009.02.002 · Cited by 208

VEGF Signals through ATF6 and PERK to Promote Endothelial Cell Survival and Angiogenesis in the Absence of ER Stress

Karali, E., Bellou, S., Stellas, D., Klinakis, A., Murphy, C., & Fotsis, T. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.03.022 · Cited by 214

Localization of mTORC2 activity inside cells

Ebner, M., Sinkovics, B., Szczygieł, M., Ribeiro, D. W., & Yudushkin, I. A. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201610060 · Cited by 214

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

Sánchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Calejman, C. M., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.10.008 · Cited by 204

The Alzheimer's disease mitochondrial cascade hypothesis: an update

Swerdlow, R. H., & Khan, S. M. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.01.011 · Cited by 206

Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2

Yu, K., Shi, C., Toral‐Barza, L., Lucas, J., Shor, B., Kim, J. E., Zhang, W., Mahoney, R., Gaydos, C., Tardio, L., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-2340 · Cited by 214

Untitled work

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PIM kinase (and Akt) biology and signaling in tumors

Warfel, N. A., & Kraft, A. S. (2015) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2015.03.001 · Cited by 209

PIK3CA/PTEN Mutations and Akt Activation As Markers of Sensitivity to Allosteric mTOR Inhibitors

Meric‐Bernstam, F., Akçakanat, A., Chen, H., Do, K.-A., Sangai, T., Adkins, F. C., Gonzalez-Angulo, A. M., Rashid, A., Crosby, K., Dong, M., et al. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-2123 · Cited by 212

4E-Binding Protein 1, A Cell Signaling Hallmark in Breast Cancer that Correlates with Pathologic Grade and Prognosis

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Research progress of mTOR inhibitors

Chen, Y., & Zhou, X. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.112820 · Cited by 219

Beyond ATM: The protein kinase landscape of the DNA damage response

Bensimon, A., Aebersold, R. H., & Shiloh, Y. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.05.013 · Cited by 214

Stress-Responsive Sestrins Link p53 with Redox Regulation and Mammalian Target of Rapamycin Signaling

Budanov, A. V. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3530 · Cited by 208

TOR regulation of AGC kinases in yeast and mammals

Jacinto, E., & Lorberg, A. (2008) · Biochemical Journal · doi:10.1042/bj20071518 · Cited by 203

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid

Lee, H.-K., Kumar, P., Fu, Q., Rosen, K. M., & Querfurth, H. W. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-07-0777 · Cited by 185

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

Leiria, L. O., Wang, C., Lynes, M. D., Yang, K., Shamsi, F., Sato, M. M., Sugimoto, S., Chen, E. Y.-S., Bussberg, V., Narain, N. R., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2019.07.001 · Cited by 205

mTOR-Dependent Cell Survival MechanismsPreprint

Hung, C., García-Haro, L., Sparks, C. A., & Guertin, D. A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a008771 · Cited by 215

Sirolimus Reduces Polycystic Liver Volume in ADPKD Patients

Qian, Q., Du, H., King, B. F., Kumar, S., Dean, P. G., Cosio, F. G., & Torres, V. E. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007050626 · Cited by 203

Human Muscle Fiber Type–Specific Insulin Signaling: Impact of Obesity and Type 2 Diabetes

Albers, P. H., Pedersen, A. J. T., Birk, J. B., Steenberg, D. E., Vind, B. F., Baba, O., Nøhr, J., Højlund, K., & Wojtaszewski, J. F. P. (2014) · Diabetes · doi:10.2337/db14-0590 · Cited by 207

Implications of Phosphoinositide 3-Kinase-Akt (PI3K-Akt) Pathway in the Pathogenesis of Alzheimer’s Disease

Kumar, M., & Bansal, N. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02611-7 · Cited by 208

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review)

Xie, Y., Shi, X., Sheng, K., Han, G., Li, W., Zhao, Q., Jiang, B., Feng, J., Li, J., & Gu, Y. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9713 · Cited by 505

Curcumin Disrupts the Mammalian Target of Rapamycin-Raptor Complex

Beevers, C. S., Chen, L., Liu, L., Luo, Y., Webster, N. J. G., & Huang, S. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2367 · Cited by 208

Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management

de Theije, C. G. M., Wu, J., da Silva, S. L., Kamphuis, P. J. G. H., Garssen, J., Korte, S. M., & Kraneveld, A. D. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.07.013 · Cited by 212

PRR5, a Novel Component of mTOR Complex 2, Regulates Platelet-derived Growth Factor Receptor β Expression and Signaling

Woo, S.-Y., Kim, D., Jun, C., Kim, Y. M., Haar, E. V., Lee, S.-I., Hegg, J. W., Bandhakavi, S., Griffin, T. J., & Kim, D. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704343200 · Cited by 206

Building mammalian signalling pathways with RNAi screens

Moffat, J., & Sabatini, D. M. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1860 · Cited by 204

Overview of current targeted therapy in gallbladder cancer

Song, X., Hu, Y., Li, Y., Shao, R., Liu, F., & Liu, Y. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00324-2 · Cited by 208

Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis

Nassour, J., Aguiar, L. G., Correia, A., Schmidt, T. T., Mainz, L., Przetocka, S., Haggblom, C., Tadepalle, N., Williams, A. E., Shokhirev, M. N., et al. (2023) · Nature · doi:10.1038/s41586-023-05710-8 · Cited by 210

Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency

Wang, S., Xia, P., Ye, B., Huang, G., Liu, J., & Fan, Z. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.10.005 · Cited by 209

PI3K and mTOR Signaling Pathways in Cancer: New Data on Targeted Therapies

Willems, L., Tamburini, J., Chapuis, N., Lacombe, C., Mayeux, P., & Bouscary, D. (2012) · Current Oncology Reports · doi:10.1007/s11912-012-0227-y · Cited by 208

ErbB2 Increases Vascular Endothelial Growth Factor Protein Synthesis via Activation of Mammalian Target of Rapamycin/p70S6K Leading to Increased Angiogenesis and Spontaneous Metastasis of Human Breast Cancer Cells

Klos, K. S., Wyszomierski, S. L., Sun, M., Tan, M., Zhou, X., Li, P., Yang, W., Yin, G., Hittelman, W. N., & Yu, D. (2006) · Cancer Research · doi:10.1158/0008-5472.can-04-4559 · Cited by 201

Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass

Frost, R. A., & Lang, C. H. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00089.2007 · Cited by 200

Macropinocytosis confers resistance to therapies targeting cancer anabolism

Jayashankar, V., & Edinger, A. L. (2020) · Nature Communications · doi:10.1038/s41467-020-14928-3 · Cited by 200

Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders

Maiese, K. (2015) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12804 · Cited by 202

Fine tuning the immune response with PI3K

Fruman, D. A., & Bismuth, G. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00750.x · Cited by 207

Mitochondria Associated Membranes (MAMs): Architecture and physiopathological role

Barazzuol, L., Giamogante, F., & Calí, T. (2021) · Cell Calcium · doi:10.1016/j.ceca.2020.102343 · Cited by 213

Cancer stem cells: landscape, challenges and emerging therapeutic innovations

Lee, H., Kim, B., Park, J., Park, S., Yoo, G., Yum, S., Kang, W., Lee, J., Youn, H., & Youn, B. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02360-2 · Cited by 247

Human Cytomegalovirus Protein UL38 Inhibits Host Cell Stress Responses by Antagonizing the Tuberous Sclerosis Protein Complex

Moorman, N. J., Cristea, I. M., Terhune, S. S., Rout, M. P., Chait, B. T., & Shenk, T. (2008) · Cell Host & Microbe · doi:10.1016/j.chom.2008.03.002 · Cited by 194

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

Green, A. S., Chapuis, N., Trovati Maciel, T., Willems, L., Lambert, M., Arnoult, C., Boyer, O., Bardet, V., Park, S., Foretz, M., et al. (2010) · Blood · doi:10.1182/blood-2010-02-269837 · Cited by 199

The role of autophagy in tumour development and cancer therapy

Rosenfeldt, M. T., & Ryan, K. M. (2009) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399409001306 · Cited by 203

Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin

Bhagwat, S. V., Gokhale, P. C., Crew, A. P. A., Cooke, A., Yao, Y., Mantis, C., Kahler, J., Workman, J. E., Bittner, M., Dudkin, L., et al. (2011) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-10-1099 · Cited by 203

Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development

Kawazu, M., Saso, K., Tong, K. I., McQuire, T., Goto, K., Son, D.-O., Wakeham, A. C., Miyagishi, M., Mak, T. W., & Okada, H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017830 · Cited by 201

The secret life of kinases: functions beyond catalysis

Rauch, J., Volinsky, N., Romano, D., & Kölch, W. (2011) · Cell Communication and Signaling · doi:10.1186/1478-811x-9-23 · Cited by 209

The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation

Walters, B. J., Mercaldo, V., Gillon, C. J., Yip, M., Neve, R. L., Boyce, F. M., Frankland, P. W., & Josselyn, S. A. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.31 · Cited by 197

Strategies for the Selective Regulation of Kinases with Allosteric Modulators: Exploiting Exclusive Structural Features

Fang, Z., Grütter, C., & Rauh, D. (2013) · ACS Chemical Biology · doi:10.1021/cb300663j · Cited by 197

The Human Papillomavirus Type 16 E6 Oncoprotein Activates mTORC1 Signaling and Increases Protein Synthesis

Spangle, J. M., & Münger, K. (2010) · Journal of Virology · doi:10.1128/jvi.00974-10 · Cited by 204

Activation of Mammalian Target of Rapamycin Signaling Pathway Contributes to Tumor Cell Survival in Anaplastic Lymphoma Kinase–Positive Anaplastic Large Cell Lymphoma

Vega, F., Medeiros, L. J., Leventaki, V., Atwell, C., Cho‐Vega, J. H., Tian, L., Claret, F.-X., & Rassidakis, G. Z. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3018 · Cited by 194

TOR Complex 2 Integrates Cell Movement during Chemotaxis and Signal Relay in Dictyostelium

Lee, S. D., Comer, F. I., Sasaki, A. T., McLeod, I. X., Duong, Y., Okumura, K., Yates, J. R., Parent, C. A., & Firtel, R. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-04-0342 · Cited by 191

PDK1: At the crossroad of cancer signaling pathways

Gagliardi, P. A., Puliafito, A., & Primo, L. (2017) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2017.04.014 · Cited by 196

Mechanism of resistance to endocrine therapy in breast cancer: the important role of PI3K/Akt/mTOR in estrogen receptor-positive, HER2-negative breast cancer

Araki, K., & Miyoshi, Y. (2017) · Breast Cancer · doi:10.1007/s12282-017-0812-x · Cited by 201

Propionate suppresses hepatic gluconeogenesis via GPR43/AMPK signaling pathway

Yoshida, H., Ishii, M., & Akagawa, M. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.07.022 · Cited by 206

Regulation of mRNA Translation by Signaling PathwaysPreprint

Roux, P. P., & Topisirovic, I. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012252 · Cited by 206

Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling

Tato, I., Bartrons, R., Ventura, F., & Rosa, J. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.166991 · Cited by 201

Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer

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The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex

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