The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Antibiotics and Antibiotic Resistance Genes in Natural Environments
Abstract
The large majority of antibiotics currently used for treating infections and the antibiotic resistance genes acquired by human pathogens each have an environmental origin. Recent work indicates that the function of these elements in their environmental reservoirs may be very distinct from the “weapon-shield” role they play in clinical settings. Changes in natural ecosystems, including the release of large amounts of antimicrobials, might alter the population dynamics of microorganisms, including selection of resistance, with consequences for human health that are difficult to predict.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Sampling the Antibiotic Resistome
D'Costa, V. M., McGrann, K. M., Hughes, D. W., & Wright, G. D. (2006) · Science · doi:10.1126/science.1120800 · Cited by 1,594
SOS response promotes horizontal dissemination of antibiotic resistance genes
Beaber, J. W., Hochhut, B., & Waldor, M. K. (2004) · Nature · doi:10.1038/nature02241 · Cited by 1,186
Cited by
Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer
von Wintersdorff, C. J. H., Penders, J., van Niekerk, J. M., Mills, N. D., Majumder, S., van Alphen, L. B., Savelkoul, P. H. M., & Wolffs, P. F. G. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00173 · Cited by 1,707
The shared antibiotic resistome of soil bacteria and human pathogens
Forsberg, K. J., Reyes, A., Wang, B., Selleck, E. M., Sommer, M. O. A., & Dantas, G. (2012) · Science · doi:10.1126/science.1220761 · Cited by 1,650
A brief history of the antibiotic era: lessons learned and challenges for the future
Aminov, R. I. (2010) · Frontiers in Microbiology · doi:10.3389/fmicb.2010.00134 · Cited by 1,628
Ecological effects of antibiotics on natural ecosystems: A review
Grenni, P., Ancona, V., & Barra Caracciolo, A. (2018) · Microchemical Journal · doi:10.1016/j.microc.2017.02.006 · Cited by 1,257
Environmental factors influencing the development and spread of antibiotic resistance
Bengtsson-Palme, J., Kristiansson, E., & Larsson, D. G. J. (2018) · FEMS Microbiology Reviews · doi:10.1093/femsre/fux053 · Cited by 1,167
In-feed antibiotic effects on the swine intestinal microbiome
Looft, T., Johnson, T. A., Allen, H. K., Bayles, D. O., Alt, D. P., Stedtfeld, R. D., Sul, W. J., Stedtfeld, T. M., Chai, B., Cole, J. R., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1120238109 · Cited by 1,072
Evidence of Increasing Antibiotic Resistance Gene Abundances in Archived Soils since 1940
Knapp, C. W., Dolfing, J., Ehlert, P. A. I., & Graham, D. W. (2010) · Environmental Science & Technology · doi:10.1021/es901221x · Cited by 837
Sui, Q., Cao, X., Lu, S., Zhao, W., Qiu, Z., & Yu, G. (2015) · Emerging Contaminants · doi:10.1016/j.emcon.2015.07.001 · Cited by 664
Karkman, A., Pärnänen, K., & Larsson, D. G. J. (2019) · Nature Communications · doi:10.1038/s41467-018-07992-3 · Cited by 628
Co-occurrence of antibiotic and metal resistance genes revealed in complete genome collection
Li, L.-G., Xia, Y., & Zhang, T. (2017) · The ISME Journal · doi:10.1038/ismej.2016.155 · Cited by 528
Evolution of high-level resistance during low-level antibiotic exposure
Wistrand-Yuen, E., Knopp, M., Hjort, K., Koskiniemi, S., Berg, O. G., & Andersson, D. I. (2018) · Nature Communications · doi:10.1038/s41467-018-04059-1 · Cited by 466
Current and Emerging Methods of Antibiotic Susceptibility Testing
Khan, Z. A., Siddiqui, M. F., & Park, S. (2019) · Diagnostics · doi:10.3390/diagnostics9020049 · Cited by 442
Streptomyces as symbionts: an emerging and widespread theme?
Seipke, R. F., Kaltenpoth, M., & Hutchings, M. I. (2012) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00313.x · Cited by 417
Selective pressure of antibiotic pollution on bacteria of importance to public health
Tello, A., Austin, B., & Telfer, T. C. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104650 · Cited by 383
Yi, X., Tran, N. H., Yin, T., He, Y., & Gin, K. Y.-H. (2017) · Water Research · doi:10.1016/j.watres.2017.05.008 · Cited by 336
Occurrence, Transformation, and Fate of Antibiotics in Municipal Wastewater Treatment Plants
Zhang, T., & Li, B. (2011) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643380903392692 · Cited by 313
Song, J., Rensing, C., Holm, P. E., Virta, M., & Brandt, K. K. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.6b05342 · Cited by 200
Loss of soil microbial diversity exacerbates spread of antibiotic resistance
Chen, Q.-L., An, X.-L., Zheng, B.-X., Gillings, M., Peñuelas, J., Cui, L., Su, J.-Q., & Zhu, Y.-G. (2019) · Soil Ecology Letters · doi:10.1007/s42832-019-0011-0 · Cited by 131
Role of Quaternary Ammonium Compounds on Antimicrobial Resistance in the Environment
Tezel, U., & Pavlostathis, S. G. (2011) · Antimicrobial Resistance in the Environment · doi:10.1002/9781118156247.ch20 · Cited by 90
Metagenomic Insights into Transferable Antibiotic Resistance in Oral Bacteria
Sukumar, S., Roberts, A. P., Martin, F. E., & Adler, C. J. (2016) · Journal of Dental Research · doi:10.1177/0022034516648944 · Cited by 84
Lopatkin, A. J., Sysoeva, T. A., & You, L. (2016) · BioEssays · doi:10.1002/bies.201600133 · Cited by 83
Using Combination Therapy to Thwart Drug Resistance
Hill, J. A., & Cowen, L. E. (2015) · Future Microbiology · doi:10.2217/fmb.15.68 · Cited by 75
Ouyang, W.-Y., Birkigt, J., Richnow, H. H., & Adrian, L. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.0c03407 · Cited by 73
Saifur, S., & Gardner, C. M. (2021) · Water Science and Technology · doi:10.2166/wst.2021.187 · Cited by 54
Peng, S., Zheng, H., Herrero-Fresno, A., Olsen, J. E., Dalsgaard, A., & Ding, Z. (2021) · Science of The Total Environment · doi:10.1016/j.scitotenv.2021.148259 · Cited by 51
Foxes As a Potential Wildlife Reservoir for mecA -Positive Staphylococci
Carson, M., Meredith, A. L., Shaw, D. J., Giotis, E. S., Lloyd, D. H., & Loeffler, A. (2012) · Vector-Borne and Zoonotic Diseases · doi:10.1089/vbz.2011.0825 · Cited by 23
Field, W., & Hershberg, R. (2015) · Genome Biology and Evolution · doi:10.1093/gbe/evv102 · Cited by 19
Hung, W.-C., Rugh, M., Feraud, M., Avasarala, S., Kurylo, J., Gutierrez, M., Jimenez, K., Truong, N., Holden, P. A., Grant, S. B., et al. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127469 · Cited by 17
Environmental Protection Strategies: An Overview
Malik, A., Rahman, M., Ansari, M. I., Masood, F., & Grohmann, E. (2012) · Environmental Protection Strategies for Sustainable Development · doi:10.1007/978-94-007-1591-2_1 · Cited by 11
Metadata
- Authors
- Martínez, J. L.
- Venue
- Science
- Published
- 2008-07-18
- Volume
- 321
- Issue
- 5887
- Pages
- 365-367
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1964071916
- Cited by
- 1,795
- References
- 2
- FWCI
- 42.51
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.