Modalities, Modes, and Models in Functional Neuroimaging
Abstract
In this, the 21st century, human-brain mapping celebrates 21 years of cognitive activation studies. This review looks at imaging neuroscience and key ideas it has pursued; some ideas portend exciting developments, and others have failed gloriously. In terms of achievements, there is much to celebrate, in the sense that it is difficult to imagine modern neuroscience without brain imaging. I will look at recent advances from the perspectives of functional segregation and integration in the brain, paying special attention to approaches that deal with the distributed and integrated nature of neuronal processing and the questions they address.
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Effective connectivity measures the causal relationship between regions, for example Granger causality.
“This sets functional connectivity apart from directional connectivity or effective connectivity (94), which measures the causal relationship between A and B, e.g. Granger causality (95).”
From Electrophysiological source imaging: A noninvasive window to brain dynamics (2018) · cites this paper as [94]
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- Authors
- Friston, K. J.
- Affiliations
- Wellcome Centre for Human Neuroimaging (GB)
- Corresponding author
- Friston, Karl J.
- ORCID
- Friston, Karl J.
- Venue
- Science
- Published
- 2009-10-16
- Volume
- 326
- Issue
- 5951
- Pages
- 399-403
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1983451956
- Cited by
- 489
- References
- 46
- Citations by year
- 2026: 13 · 2025: 19 · 2024: 26 · 2023: 21 · 2022: 18 · 2021: 27 · 2020: 23 · 2019: 31 · 2018: 34 · 2017: 30 · 2016: 35 · 2015: 27 · 2014: 42 · 2013: 44 · 2012: 33
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Wellcome Trust (088130)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- functional neuroimaging, brain mapping, functional segregation, functional integration, imaging modalities
- MeSH terms
- Brain, Brain Mapping, Electroencephalography, Humans, Magnetic Resonance Imaging, Mental Processes, Models, Neurological, Neurons, Models, Statistical, Computational Biology
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