Cited by 489Functional Brain Connectivity StudiesAdvanced Neuroimaging Techniques and ApplicationsNeural and Behavioral Psychology Studies

Modalities, Modes, and Models in Functional Neuroimaging

Friston, Karl J.·2009·Science

Abstract

In this, the 21st century, human-brain mapping celebrates 21 years of cognitive activation studies. This review looks at imaging neuroscience and key ideas it has pursued; some ideas portend exciting developments, and others have failed gloriously. In terms of achievements, there is much to celebrate, in the sense that it is difficult to imagine modern neuroscience without brain imaging. I will look at recent advances from the perspectives of functional segregation and integration in the brain, paying special attention to approaches that deal with the distributed and integrated nature of neuronal processing and the questions they address.

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Crossref · 10.1126/science.1174521

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46 of 46 references verified0 citation errors · 0 not checkable

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  • Effective connectivity measures the causal relationship between regions, for example Granger causality.

    “This sets functional connectivity apart from directional connectivity or effective connectivity (94), which measures the causal relationship between A and B, e.g. Granger causality (95).”

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Authors
Friston, K. J.
Affiliations
Wellcome Centre for Human Neuroimaging (GB)
Corresponding author
Friston, Karl J.
Venue
Science
Published
2009-10-16
Volume
326
Issue
5951
Pages
399-403
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1983451956
Cited by
489
References
46
Citations by year
2026: 13 · 2025: 19 · 2024: 26 · 2023: 21 · 2022: 18 · 2021: 27 · 2020: 23 · 2019: 31 · 2018: 34 · 2017: 30 · 2016: 35 · 2015: 27 · 2014: 42 · 2013: 44 · 2012: 33
FWCI
2.46
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
Wellcome Trust (088130)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
functional neuroimaging, brain mapping, functional segregation, functional integration, imaging modalities
MeSH terms
Brain, Brain Mapping, Electroencephalography, Humans, Magnetic Resonance Imaging, Mental Processes, Models, Neurological, Neurons, Models, Statistical, Computational Biology

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