Cited by 148Stress Responses and CortisolMemory and Neural MechanismsAdrenal Hormones and Disorders

Corticosteroid responses to limbic stimulation in man: Localization of stimulus sites

Rubin, Robert T., Mandell, Arnold J., Crandall, Paul H.·1966·Science

Abstract

Corticosteroids in human plasma and urine increase after amygdala stimulation, and plasma corticosteroids decrease after hippocampus stimulation. Five subjects underwent unilateral temporal lobectomy, and histopathologic localization of electrode sites was attempted. Localization was successful for six sites: three in basolateral amygdala and three in hippocampus.

Integrity signals

Registry

Crossref · 10.1126/science.153.3737.767

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Electrical stimulation of the amygdala can produce fear, anxiety, dysphoria, sympathetic autonomic arousal, social withdrawal, and cortisol release.

    “Electrical stimulation of the amygdala can produce fear, anxiety, dysphoria, sympathetic autonomic arousal, social withdrawal, and cortisol release (61, 62).”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Rubin, R. T., Mandell, A. J., & Crandall, P. H.
Affiliations
  • Departments of Psychiatry and Neurosurgery, University of California Center for the Health Sciences, Los Angeles 90024
  • University of California, Los Angeles (US)
Venue
Science
Published
1966-08-12
Volume
153
Issue
3737
Pages
767-768
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1976647119
Cited by
148
References
4
Citations by year
2025: 2 · 2023: 1 · 2022: 5 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 3 · 2016: 9 · 2015: 5 · 2014: 7 · 2013: 1 · 2012: 10
FWCI
2.69
Type
journal article
Language
en
Open access
closed
Locations
  • Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords
corticosteroids, limbic system, amygdala, hippocampus, temporal lobectomy, electrical stimulation, plasma corticosteroids, urinary corticosteroids, basolateral amygdala
MeSH terms
Amygdala, Blood, Electric Stimulation, Electrophysiology, Hippocampus, Humans, Urine, 17-Hydroxycorticosteroids, In Vitro Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review