A Gender Gap in Autoimmunity: Task Force on Gender, Multiple Sclerosis and Autoimmunity
Abstract
Relationship of Motor Impairment with Cognitive and Emotional Alterations in Patients with Multiple Sclerosis,
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Autoimmune diseases change in severity during puberty, menses, pregnancy, menopause, and times of stress.
“In addition, autoimmune diseases change in severity during puberty, menses, pregnancy, menopause, and times of stress (40).”
From Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation (2000) · cites this paper as [40]
Many autoimmune diseases exhibit a significant sexual dimorphism.
“Many autoimmune diseases have been found to exhibit a significant sexual dimorphism, including autoimmune thyroiditis, systemic lupus erythematous, and rheumatoid arthritis.”
From Interleukin-6 is an essential, corticotropin-releasing hormone-independent stimulator of the adrenal axis during immune system activation (2000) · cites this paper as [40]
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- Authors
- Whitacre, C. C., Reingold, S. C., O'Looney, P. A., Blankenhorn, E., Brinley, F., Collier, E., Duquette, P., Fox, H., Giesser, B., Gilmore, W., Lahita, R., Nelson, J. L., Reiss, C., Riskind, P., & Voskuhl, R.
- Affiliations
- The Ohio State University (US)
- National Multiple Sclerosis Society (US)
- ORCID
- Venue
- Science
- Published
- 1999-02-26
- Volume
- 283
- Issue
- 5406
- Pages
- 1277-1278
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1543098232
- Cited by
- 851
- References
- 3
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 15 · 2023: 19 · 2022: 34 · 2021: 24 · 2020: 25 · 2019: 31 · 2018: 22 · 2017: 28 · 2016: 40 · 2015: 35 · 2014: 29 · 2013: 28 · 2012: 42
- FWCI
- 23.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Keywords
- gender gap, autoimmunity, multiple sclerosis, motor impairment, cognitive impairment, emotional change
- MeSH terms
- Animals, Antibody Formation, Autoimmune Diseases, Female, Hormones, Humans, Immunity, Cellular, Male, Pregnancy, Pregnancy Complications, Sex Characteristics, Gonadal Steroid Hormones, Autoimmunity, Cytokines, Th1 Cells, Th2 Cells, Genetic Predisposition to Disease
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