Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
Kim, Nam W., Piatyszek, Mieczyslaw A., Prowse, Karen R., Harley, Calvin B., West, Michael D., Ho, Peter L. C., Coviello, Gina M., Wright, Woodring E., Weinrich, Scott L., Shay, Jerry W.·1994·Science
Cited by (1,043)
Items 1,001–1,043 of 1,043
- Cellular lifespan and senescence signaling in embryonic stem cellsMiura, Takumi, Mattson, Mark P., Rao, Mahendra S. · 2004 · Aging Cell
- Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domainsBroccoli, D · 1997 · Human Molecular Genetics
- Smurf2 up-regulation activates telomere-dependent senescenceZhang, Hong, Cohen, Stanley N. · 2004 · Genes & Development
- Involvement of the INK4a/Arf gene locus in senescenceCollins, Carol J., Sedivy, John M. · 2003 · Aging Cell
- Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributionsWerner, Benjamin, Beier, Fabian, Hummel, Sebastian, Balabanov, Stefan, Lassay, Lisa, Orlikowsky, Thorsten, Dingli, David, Brümmendorf, Tim H, Traulsen, Arne · 2015 · eLife
- Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteinsLudlow, Andrew T., Ludlow, Lindsay W., Roth, Stephen M. · 2013 · BioMed Research International
- Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the female lung cancer consortium in AsiaMachiela, Mitchell J., Hsiung, Chao Agnes, Shu, Xiao‐Ou, Seow, Wei Jie, Wang, Zhaoming, Matsuo, Keitaro, Hong, Yun‐Chul, Seow, Adeline, Wu, Chen, Hosgood, H. Dean et al. · 2015 · International Journal of Cancer
- Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expressionWood, Lauren D, Halvorsen, Tanya L, Dhar, Sonu, Baur, Joseph A, Pandita, Raj K, Wright, Woodring E, Hande, M Prakash, Calaf, Gloria, Hei, Tom K, Levine, Fred et al. · 2001 · Oncogene
- Short-term gain, long-term pain: the senescence life cycle and cancerChan, Adelyne Sue Li, Narita, Masashi · 2019 · Genes & Development
- Telomere length in human liver diseasesUrabe, Yoshiaki, Nouso, Kazuhiro, Higashi, Toshihiro, Nakatsukasa, Harushige, Hino, Naoki, Ashida, Kouzou, Kinugasa, Nobuyuki, Yoshida, Keigo, Uematsu, Shuji, Tsuji, Takao · 1996 · Liver
- Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 (‘Telomelysin-RGD’)Taki, Masaki, Kagawa, Shunsuke, Nishizaki, Masahiko, Mizuguchi, Hiroyuki, Hayakawa, Takao, Kyo, Satoru, Nagai, Katsuyuki, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi · 2005 · Oncogene
- Telomeres, telomerase and colorectal cancerBertorelle, Roberta · 2014 · World Journal of Gastroenterology
- Reprogramming of Telomerase by Expression of Mutant Telomerase RNA Template in Human Cells Leads to Altered Telomeres That Correlate with Reduced Cell ViabilityMarušić, Lidica, Anton, Martina, Tidy, Antonella, Wang, Ping, Villeponteau, Bryant, Bacchetti, Silvia · 1997 · Molecular and Cellular Biology
- Development of Retinoblastoma in the Absence of Telomerase ActivityGupta, J., Han, L.-P., Wang, P., Gallie, B. L., Bacchetti, S. · 1996 · JNCI Journal of the National Cancer Institute
- Enhanced antitumor efficacy of telomerase‐selective oncolytic adenoviral agent OBP‐401 with docetaxel: Preclinical evaluation of chemovirotherapyFujiwara, Toshiya, Kagawa, Shunsuke, Kishimoto, Hiroyuki, Endo, Yoshikatsu, Hioki, Masayoshi, Ikeda, Yoshihiro, Sakai, Ryo, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi · 2006 · International Journal of Cancer
- Visualization of Intrathoracically Disseminated Solid Tumors in Mice with Optical Imaging by Telomerase-Specific Amplification of a Transferred Green Fluorescent Protein GeneUmeoka, Tatsuo, Kawashima, Takeshi, Kagawa, Shunsuke, Teraishi, Fuminori, Taki, Masaki, Nishizaki, Masahiko, Kyo, Satoru, Nagai, Katsuyuki, Urata, Yasuo, Tanaka, Noriaki et al. · 2004 · Cancer Research
- Telomerase Maintains Telomere Structure in Normal Human CellsMasutomi, Kenkichi, Yu, Evan Y., Khurts, Shilagardy, Ben-Porath, Ittai, Currier, Jennifer L., Metz, Geoffrey B., Brooks, Mary W., Kaneko, Shuichi, Murakami, Seishi, DeCaprio, James A. et al. · 2003 · Cell
- Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesionsBachor, Cosima, Bachor, Oskar Alexander, Boukamp, Petra · 1999 · Journal of Cancer Research and Clinical Oncology
- The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligaseSanduja, Sandhya, Kaza, Vimala, Dixon, Dan A. · 2009 · Aging
- Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypesMachiela, Mitchell J., Lan, Qing, Slager, Susan L., Vermeulen, Roel C.H., Teras, Lauren R., Camp, Nicola J., Cerhan, James R., Spinelli, John J., Wang, Sophia S., Nieters, Alexandra et al. · 2016 · Human Molecular Genetics
- Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenograftsOzawa, Tomoko, Gryaznov, Sergei M., Hu, Lily J., Pongracz, Krisztina, Santos, Raquel A., Bollen, Andrew W., Lamborn, Kathleen R., Deen, Dennis F. · 2004 · Neuro-Oncology
- Constitutively active DNA damage checkpoint pathways as the driving force for the high frequency of p53 mutations in human cancerHalazonetis, Thanos D. · 2004 · DNA repair
- Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenitaLy, H. · 2005 · Blood
- The Role of Telomerase Expression and Telomere Length Maintenance in Human and MouseNan-PIng, Weng, Hodes, Richard J. · 2000 · Journal of Clinical Immunology
- The Rb-Related p130 Protein Controls Telomere Lengthening through an Interaction with a Rad50-Interacting Protein, RINT-1Kong, Ling-Jie, Meloni, Alison R., Nevins, Joseph R. · 2006 · Molecular Cell
- Telomerase Activity Is Decreased in Peripheral Blood Mononuclear Cells of Hemodialysis PatientsTsirpanlis, George, Chatzipanagiotou, Stylianos, Boufidou, Fotini, Kordinas, Vasileios, Alevyzaki, Fotini, Zoga, Margarita, Kyritsis, Ilias, Stamatelou, Kyriaki, Triantafyllis, George, Nicolaou, Chrysoula · 2006 · American Journal of Nephrology
- Telomere length and frailty in older adults-a systematic review and meta-analysisAraújo Carvalho, Aline Carla, Tavares Mendes, Mário Luis, da Silva Reis, Monique Carla, Santos, Victor Santana, Tanajura, Diego Moura, Martins-Filho, Paulo Ricardo Saquete · 2019 · Ageing Research Reviews
- Telomerase activity in ductal carcinoma in situ of the breastShpitz, B., Zimlichman, S., Zemer, R., Bomstein, Y., Zehavi, T., Liverant, S., Bernehim, J., Kaufman, Z., Klein, E., Shapira, Y. et al. · 1999 · Breast Cancer Research and Treatment
- Telomeric fusions in cultured human fibroblasts as a source of genomic instabilityRiboni, Roberta, Casati, Alessandra, Nardo, Tiziana, Zaccaro, Elisabetta, Ferretti, Luca, Nuzzo, Fiorella, Mondello, Chiara · 1997 · Cancer Genetics and Cytogenetics
- Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat)Senthilkumar, P.K., Klingelhutz, A.J., Jacobus, J.A., Lehmler, H., Robertson, L.W., Ludewig, G. · 2011 · Toxicology Letters
- Dedifferentiation of conditionally immortalized hepatocytes with long-term in vitro passageKim, Byung-Ho, Sung, Se-Ra, Choi, Eun-Hee, Kim, Young-Il, Kim, Kyeong-Jin, Dong, Seok-Ho, Kim, Hyo-Jong, Chang, Young-Woon, Lee, Joung-Il, Chang, Rin · 2000 · Experimental & Molecular Medicine
- Natural products targeting telomere maintenanceChen, Jack Li-Yang, Sperry, Jonathan, Ip, Nancy Y., Brimble, Margaret A. · 2011 · MedChemComm
- Accelerated Aging during Chronic Oxidative Stress: A Role for PARP-1Boesten, Daniëlle M. P. H. J., de Vos-Houben, Joyce M. J., Timmermans, Leen, den Hartog, Gertjan J. M., Bast, Aalt, Hageman, Geja J. · 2013 · Oxidative Medicine and Cellular Longevity
- Review of hTERT-Immortalized Cells: How to Assess Immortality and Confirm IdentityShitova, Maria, Alpeeva, Elena, Vorotelyak, Ekaterina · 2024 · International Journal of Molecular Sciences
- Telomere length recovery: a strong predictor of overall survival in acute promyelocytic leukemiaBaljevic, Muhamed, Dumitriu, Bogdan, Lee, Ju-Whei, Paietta, Elisabeth M., Wiernik, Peter H., Racevskis, Janis, Chen, Christina, Stein, Eytan M., Gallagher, Robert E., Rowe, Jacob M. et al. · 2016 · Acta Haematologica
- The Presence of Telomere Fusion in Sporadic Colon Cancer Independently of Disease Stage, TP53/KRAS Mutation Status, Mean Telomere Length, and Telomerase ActivityTanaka, Hiromi, Beam, Matthew J., Caruana, Kevin · 2014 · Neoplasia
- Renal phenotype of young and old telomerase-deficient miceSchildhorn, Carolin, Jacobi, Christoph, Weißbrodt, Andrea, Hermstedt, Christine, Westhoff, Jens Hendrik, Hömme, Meike, Bhayadia, Raj, Gretz, Norbert, Falk, Christine Susanne, Schmitt, Roland et al. · 2015 · Mechanisms of Ageing and Development
- Age-dependent alterations of c-fos and growth regulation in human fibroblasts expressing the HPV16 E6 protein.Yan, Y, Ouellette, M M, Shay, J W, Wright, W E · 1996 · Molecular Biology of the Cell
- Phase 1 trial of 4-1BB-based adoptive T-cell therapy targeting human telomerase reverse transcriptase in patients with advanced refractory solid tumorsChoi, Wonyoung, Lee, Youngjoo, Choi, Beom K., Park, Bo-Mi, Kim, Young H., Yun, Tak, Lee, Woo Jin, Yoo, Heon, Baek, Ji Yeon, Woo, Sang Myung et al. · 2023 · Cytotherapy
- Telomerase activity in human germline and embryonic tissues and cellsWright, Woodring E., Piatyszek, Mieczyslaw A., Rainey, William E., Byrd, William, Shay, Jerry W. · 1996 · Developmental Genetics
- Cellular senescence and cancer1999
- Untitled workAllen · 1999 · 10.1002/(sici)1097-4652(199907)180:1
- Untitled work2003 · PubMed