The Clonal Evolution of Tumor Cell Populations: Acquired genetic lability permits stepwise selection of variant sublines and underlies tumor progression.
Nowell, Peter C.·1976·Science
Cited by (1,016)
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- A Truncated Isoform of the Protein Phosphatase 2A B56γ Regulatory Subunit May Promote Genetic Instability and Cause Tumor ProgressionIto, Akihiko, Koma, Yu-ichiro, Watabe, Kenji, Nagano, Teruaki, Endo, Yuichi, Nojima, Hiroshi, Kitamura, Yukihiko · 2003 · The American Journal of Pathology
- Thymic lymphomas arising in Msh2 deficient mice display a large increase in mutation frequency and an altered mutational spectrumZhang, Shulin, Lloyd, Ruth, Bowden, Gregory, Glickman, Barry W, de Boer, Johan G · 2002 · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Cost-Effective Real-Time Metabolic Profiling of Cancer Cell Lines for Plate-Based AssaysBlaszczak, Wiktoria, Tan, Zhengchu, Swietach, Pawel · 2021 · Chemosensors
- Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cellsBlaszczak, Wiktoria, White, Bobby, Monterisi, Stefania, Swietach, Pawel · 2024 · Cell Reports
- Cellular senescence and cancer1999
