Epigenetic plasticity and the hallmarks of cancer

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590

The hallmarks of cancer

Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Rao, S. S. P., Huntley, M. H., Durand, N. C., Stamenova, E. K., Bochkov, I. D., Robinson, J. T., Sanborn, A. L., Machol, I., Omer, A. D., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.021 · Cited by 9,212

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,951

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Jones, P. A. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3230 · Cited by 6,061

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

Parsons, D. W., Jones, S., Zhang, X., Lin, J. C.-H., Leary, R. J., Angenendt, P., Mankoo, P., Carter, H., Siu, I.-M., Gallia, G. L., et al. (2008) · Science · doi:10.1126/science.1164382 · Cited by 5,857

IDH1 and IDH2 Mutations in Gliomas

Yan, H., Parsons, D. W., Jin, G., McLendon, R., Rasheed, B. A., Yuan, W., Kos, I., Batinic-Haberle, I., Jones, S., Riggins, G. J., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808710 · Cited by 5,847

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006) · Cell · doi:10.1016/j.cell.2006.02.041 · Cited by 5,361

The Epigenomics of Cancer

Jones, P. A., & Baylin, S. B. (2007) · Cell · doi:10.1016/j.cell.2007.01.029 · Cited by 4,515

EMT: 2016

Nieto, M. A., Huang, R. Y.-J., Jackson, R. A., & Thiery, J. P. (2016) · Cell · doi:10.1016/j.cell.2016.06.028 · Cited by 4,492

Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation

Ankill, J., Zhao, Z. Q., Tekpli, X., Kure, E. H., Kristensen, V. N., Mathelier, A., & Fleischer, T. (2024) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1012565 · Cited by 4

Chromatin Accessibility as a Strategy to Detect Changes Associated With Development, Disease, and Exposure and Susceptibility to Chemical Toxins

Davis, I. J., & Pattenden, S. G. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812433-8.00003-4 · Cited by 4

Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer

Facciotto, C., Casado, J., Turunen, L., Leivonen, S., Tumiati, M., Rantanen, V., Kauppi, L., Lehtonen, R., Leppä, S., Wennerberg, K., et al. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0781-3 · Cited by 6

Advances in Diagnostic Procedures and Their Applications in the Era of Cancer Immunotherapy

Xu, M., Ergin, I., & Beyaz, S. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-41008-7_2 · Cited by 4

Extended transcriptome analysis reveals genome-wide lncRNA-mediated epigenetic dysregulation in colorectal cancer

He, S., Chen, J., Gao, H., Yang, G., Zhang, F., Ding, Y.-Q., & Zhu, H. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.11.004 · Cited by 4

Metabolic Reprogramming and Molecular Rewiring in Cancer: Therapeutic Opportunities

Meiliana, A., Dewi, N. M., & Wijaya, A. (2021) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v13i2.1598 · Cited by 3

Advances in Approaches to Study Chromatin-Mediated Epigenetic Memory

Yao, Y., Wen, Q., Zhang, T., Yu, C., Chan, K. M., & Gan, H. (2021) · ACS Synthetic Biology · doi:10.1021/acssynbio.1c00394 · Cited by 4

Regulatory patterns analysis of transcription factor binding site clustered regions and identification of key genes in endometrial cancer

Tang, X., Wang, J., Tao, H., Yuan, L., Du, G., Ding, Y., Xu, K., Bai, X., Li, Y., Sun, Y., et al. (2022) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2022.01.014 · Cited by 4

Generating Sequencing-Based DNA Methylation Maps from Low DNA Input Samples

Momani, S. A., Rodger, E. J., Stockwell, P. A., Eccles, M. R., & Chatterjee, A. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2140-0_1 · Cited by 4

Complex Elucidation of Cells-of-Origin in Pediatric Soft Tissue Sarcoma: From Concepts to Real Life, Hide-and-Seek through Epigenetic and Transcriptional Reprogramming

Savary, C., Picard, C., Corradini, N., & Castets, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116310 · Cited by 5

The Histone Demethylase HR Suppresses Breast Cancer Development through Enhanced CELF2 Tumor Suppressor Activity

Shen, Y., Singh, J., Sah, B., Chen, Z., Ha, W., Henzler, C. M., Su, T., Xie, L., Deng, Y., Li, G., et al. (2022) · Cancers · doi:10.3390/cancers14194648 · Cited by 4

The cancer epigenome: Non‐cell autonomous player in tumor immunity

Kato, S., Maeda, Y., Sugiyama, D., Watanabe, K., Nishikawa, H., & Hinohara, K. (2022) · Cancer Science · doi:10.1111/cas.15681 · Cited by 3

Pan-Cancer Analysis of the Roles and Driving Forces of RAB42

Zheng, M., Wang, W., Bu, Y., Liu, J., Ma, J., Wang, R., Ren, X., Lü, Z., Li, J., & Cai, J. (2022) · Biomolecules · doi:10.3390/biom13010043 · Cited by 4

It Runs in the Bromodomain Family: Speckled Proteins (SP) Play a Role in the Antitumor Immune Response in Solid Tumors

Rosochowicz, M. A., Lipowicz, J. M., Karwacka, M., Ostapowicz, J., Cisek, M., Mackiewicz, A. A., & Czerwińska, P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010549 · Cited by 4

Loss of Caveolin-1 Expression in Tumor Cells is Associated with Increased Aggressiveness and Cell Invasion in Oral Squamous Cell Carcinoma

Nascimento, R. B., Paiva, K. B. S., Risteli, M., Silva, L. H. S., Rodini, C. O., Rodrigues, M. F. S. D., Cicco, R. D., López, R. V. M., Salo, T. A., Nunes, F. D., et al. (2023) · Head and Neck Pathology · doi:10.1007/s12105-023-01562-w · Cited by 4

(B)On(e)-cohistones and the epigenetic alterations at the root of bone cancer

Salomoni, P., Flanagan, A. M., & Cottone, L. (2023) · Cell Death and Differentiation · doi:10.1038/s41418-023-01227-9 · Cited by 4

Misregulation of ELK1, AP1, and E12 Transcription Factor Networks Is Associated with Melanoma Progression

Singh, K., Baird, M. A., Fischer, R. S., Chaitankar, V., Seifuddin, F., Chen, Y.-C., Tunc, I., Waterman, C. M., & Pirooznia, M. (2020) · Cancers · doi:10.3390/cancers12020458 · Cited by 4

Differential Expression of Long Noncoding RNAs Reveals a Potential Biomarker for Intractable Pemphigus

Qu, P., Huang, Z., Zhu, H., Zheng, J., & Pan, M. (2021) · Disease Markers · doi:10.1155/2021/5594659 · Cited by 4

Treasure trove for cancer medicine

Tanić, M., & Beck, S. (2017) · Nature Materials · doi:10.1038/nmat5019 · Cited by 4

Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models

Ono, R., Masuya, M., Inoue, N., Shinmei, M., Ishii, S., Maegawa, Y., Maharjan, B. D., Katayama, N., & Nosaka, T. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248425 · Cited by 4

Cancer Epigenomics

Carlberg, C., & Molnár, F. (2018) · Springer eBooks · doi:10.1007/978-981-10-7614-5_10 · Cited by 4

Epigenetic inactivation of oncogenic brachyury (TBXT) by H3K27 histone demethylase controls chordoma cell survivalPreprint

Cottone, L., Hookway, E. S., Cribbs, A. P., Wells, G., Lombard, P., Ligammari, L., Tumber, A., Tirabosco, R., Amary, F. M., Szommer, T., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/432005 · Cited by 4

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC ReprogrammingPreprint

Janiszewski, A., Talón, I., Song, J., Geest, N. D., To, S. K., Bervoets, G., Marine, J., Rambow, F., & Pasque, V. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/545558 · Cited by 4

De-novo DNA Methylation of Bivalent Promoters Induces Gene Activation through PRC2 DisplacementPreprint

O’Geen, H., Mihalovits, A., Brophy, B. D., He, Y., Miller, M. W., Lee, C. J., Segal, D. J., & Tomková, M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.07.636872 · Cited by 4

A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma

Zhou, Y., Hu, Q., Wei, M., Chen, J., Shi, J., Yang, N., Jiang, L., Chen, J., Chen, Z.-Y., Yu, W., et al. (2025) · Advanced Science · doi:10.1002/advs.202504532 · Cited by 3

Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular carcinoma survival

Dzama, M. M., Sokolowski, M., Kuhlers, P. C., Brinkman, J. A., Morris, J. P., & Raab, J. R. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116619 · Cited by 4

Implications of genetic and epigenetic aberrations to the tumorigenicity of human pluripotent stem cells

Keshet, G., Barbaric, I., & Benvenisty, N. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115743 · Cited by 4

T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response

Scourzic, L., Izzo, F., Teater, M. R., Polyzos, A., Cucereavii, L., Chin, C. R., Papin, A., Pinto, H. B., Mlynarczyk, C., Tsialta, I., et al. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01833-4 · Cited by 3

Tumor microenvironment heterogeneity and immunotherapy resistance: multidimensional modulation strategies for precision breakthroughs

Wei, Y., Li, R., Xiang, Y., Tong, H., Zhang, Y., Kang, Q., Huang, J., Bao, Y., & Ma, X. (2026) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2025.12.004 · Cited by 3

Inflammatory and Epigenetic Biomarkers in Prostate Disease: Current Evidence, Clinical Limitations, and Future Multimarker Strategies

Donath-Miklos, I., Popețiu, R. O., Crişan, A. S., Vulciu, P. A., Știrbu, O., Coman, R. A., Avram, C., Goldiș, D., Roman, D. R., Chioreanu, A., et al. (2026) · Diagnostics · doi:10.3390/diagnostics16121865 · Cited by 4

Epigenetic plasticity and chemoresistance in cancer: mechanisms, biomarkers, and translational opportunities for real-world evidence

Reichert, C. O., de Aquino, N. C., Callefi, V. D. C., Alves, I., Cattena, S., Santos, E. R., Vasconcelos, K., Culler, H. F., Lage, L. A. D. P. C., Rocha, V., et al. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1786398 · Cited by 3

OCRFinder: a noise-tolerance machine learning method for accurately estimating open chromatin regions

Ren, J., Liu, Y., Zhu, X., Wang, X., Li, Y., Liu, Y., Hu, W., Zhang, X., & Wang, J. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1184744 · Cited by 3

The Nucleolar Protein C1orf131 Is a Novel Gene Involved in the Progression of Lung Adenocarcinoma Cells through the AKT Signalling Pathway

Wei, Z., Zhao, Y., Cai, J., & Xie, Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126381 · Cited by 3

A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin

Velasco, M. A. D., Sakai, K., Mitani, S., Kura, Y., Minamoto, S., Haeno, T., Hayashi, H., & Nishio, K. (2024) · International Journal of Clinical Oncology · doi:10.1007/s10147-024-02617-w · Cited by 3

Unraveling MLL1-fusion leukemia: Epigenetic revelations from an iPS cell point mutation

Kobrossy, L., Xu, W., Zhang, C., Feng, W., Turner, C. E., & Cosgrove, M. S. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107825 · Cited by 3

HDAC/σ1R Dual-Ligand as a Targeted Melanoma Therapeutic

Leotta, C. G., Barbaraci, C., Fiorito, J., Coco, A., di Giacomo, V., Amata, E., Marrazzo, A., & Pitari, G. M. (2025) · Pharmaceuticals · doi:10.3390/ph18020179 · Cited by 3

Involvement and Therapeutic Implication of JAK-STAT Pathway in Cancer

Rehman, A., Khan, N. A., Rashid, G., Tamanna, S., Jindal, R., Seth, N., Bashir, B., Mushtaq, G., Salman, M., & Parveen, S. (2025) · Springer eBooks · doi:10.1007/978-981-96-2763-9_8 · Cited by 5

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Schlosser, R., Krumbach, F., Corrales, E., Andrieux, G., Preisinger, C., Liss, F., Golzmann, A., Boerries, M., Becker, K., Knüchel, R., et al. (2025) · Molecular Oncology · doi:10.1002/1878-0261.70019 · Cited by 3

Design, synthesis and evaluation of pterostilbene-indole hybrids as potential anticancer agents

Xiao, Y., Tang, J., Zeng, S., Liu, Z., Li, L., Zou, Z., & Shang, H. (2025) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2025.130317 · Cited by 3

Overweight Mice Show Coordinated Homeostatic and Hedonic Transcriptional Response across Brain

Toma, I. D., Grabowicz, I. E., Fructuoso, M., Trujillano, D., Wilczyński, B., & Dierssen, M. (2018) · eNeuro · doi:10.1523/eneuro.0287-18.2018 · Cited by 3

Glucosinolates

Ladak, Z., Khairy, M., Armstrong, E. A., & Yager, J. Y. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820593-8.00011-2 · Cited by 3

Functionalized Lineage Tracing Can Enable the Development of Homogenization-Based Therapeutic Strategies in Cancer

Gutierrez, C., Vilas, C. K., Wu, C. J., & Al’Khafaji, A. M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.859032 · Cited by 3

The pan-cancer landscape of abnormal DNA methylation and intratumor microorganisms

Zhou, P., Lu, S. L., Chang, L., Liao, B., Cheng, M. L., Xu, X., Sui, X., Liu, F.-T., Zhang, M., Wang, Y., et al. (2023) · Neoplasia · doi:10.1016/j.neo.2023.100882 · Cited by 3

Switch/Sucrose Non-Fermentable Complex-Deficient Rhabdoid Carcinoma of Stomach: A Rare Case Report and Literature Review

Chen, M., Yao, X., Ping, J., Shen, H., Wei, Y., & Wang, W. (2023) · International Journal of Surgical Pathology · doi:10.1177/10668969221146204 · Cited by 3

Polycomb Recruiters Inside and Outside of the Repressed Domains

Erokhin, M., Mogila, V., Ломаев, Д. В., & Chetverina, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241411394 · Cited by 3

Epigenetic mechanisms of non-retinal components of the aging eye and novel therapeutic strategies

Lamas, M. (2023) · Experimental Eye Research · doi:10.1016/j.exer.2023.109673 · Cited by 3

Patient-Derived Xenografts of Breast Cancer

Marangoni, E. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-70875-6_7 · Cited by 3

Epigenetic implications in the pathogenesis of corticotroph tumors

Paes, T., Hofland, L. J., Iyer, A. M., & Feelders, R. A. (2025) · Pituitary · doi:10.1007/s11102-025-01522-3 · Cited by 3

Local and global features of genetic networks supporting a phenotypic switch

Shomar, A., Barak, O., & Brenner, N. (2020) · PLoS ONE · doi:10.1371/journal.pone.0238433 · Cited by 3

Starvation and Climate Change—How to Constrain Cancer Cell Epigenetic Diversity and Adaptability to Enhance Treatment Efficacy

Gregg, C. J. (2021) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2021.693781 · Cited by 4

Epigenetic readers and lung cancer: the rs2427964C>T variant of the bromodomain and extraterminal domain gene BRD3 is associated with poorer survival outcome in NSCLC

Lee, J. H., Yoo, S. S., Hong, M. J., Choi, J. E., Kang, H., Do, S. K., Lee, W. K., Choi, S. H., Lee, Y. H., Seo, H., et al. (2021) · Molecular Oncology · doi:10.1002/1878-0261.13109 · Cited by 3

Colorectal cancer biomarkers and their impact on the clinical practice

Crespo, J., Victorino, A. P., Araujo, K., Araujo, L. H., & Vieira, F. M. D. A. C. (2021) · Brazilian Journal of Oncology · doi:10.5935/2526-8732.20210025 · Cited by 4

Most of transcriptional alterations in glioma result from DNA-methylation independent mechanismsPreprint

Court, F., Boiteux, E. L., Fogli, A., Müller-Barthélémy, M., Vaurs‐Barrière, C., Chautard, E., Pereira, B., Biau, J., Kémény, J., Khalil, T., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/516997 · Cited by 3

Loss of SUV420H2 promotes EGFR inhibitor resistance in NSCLC through upregulation of MET via LINC01510Preprint

Pal, A. S., Agredo, A., Lanman, N. A., Clingerman, J., Gates, K., & Kasinski, A. L. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.17.995951 · Cited by 3

Independent, Diplotype and Haplotype Association Analyses of the Selected MTHFR SNPs with the Risk of Breast Cancers in a South-Asian PopulationPreprint

Ajaz, S., Zaidi, S.-E.-Z., Ali, S. M., Siddiqa, A., Memon, M. A., Abid, A., & Khaliq, S. (2021) · medRxiv · doi:10.1101/2021.03.13.21253512 · Cited by 3

METTL1 promotes Neuroblastoma development through m 7 G tRNA modification and selective oncogenic gene translationPreprint

Huang, Y., Ma, J., Yang, C., Wei, P., Yang, M., Han, H., Chen, H., Yue, T., Xiao, S., Chen, X., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1546187/v1 · Cited by 3

Rise of the Chromodomain Helicase DNA‐Binding (CHD) Chromatin Remodelling Machines

Alendar, A. (2023) · Wiley eBooks · doi:10.1002/9780470015902.a0029448 · Cited by 3

Dominant CIZ1 fragments drive epigenetic instability and are expressed in early stage cancersPreprint

Turvey, G. L., de Alba, E. L., Stewart, E., Byrom, L., Cook, H., Sofi, S., Alalti, A., Ainscough, J., Mason, A. S., Antson, A. A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.22.558821 · Cited by 2

Exploring the role of EZH2 modulation in shaping the tumor microenvironment

Fischetti, I., Michele, D. L., & Jachetti, E. (2024) · Epigenomics · doi:10.1080/17501911.2024.2410693 · Cited by 4

Specific SOX10 enhancer elements modulate phenotype plasticity and drug resistance in melanomaPreprint

DeGeorgia, S. K., & Kaufman, C. K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.12.628224 · Cited by 2

Partial erosion on under-methylated regions and chromatin reprogramming contribute to oncogene activation in IDH mutant gliomas

Wang, X., Dai, L., Liu, Y., Li, C., Fan, D., Zhou, Y., Li, P., Kong, Q., & Su, J. (2023) · Epigenetics & Chromatin · doi:10.1186/s13072-023-00490-x · Cited by 2

Unravelling epigenetic mechanisms in Cerastoderma edule genome: a comparison of healthy and neoplastic cockles

Viña-Feás, A., Temes, J., Vidal-Capón, A., Novas, S., Rodríguez‐Castro, J., Pequeño‐Valtierra, A., Pasantes, J. J., Tubío, J. M. C., & Souto, D. G. (2024) · Molecular Genetics and Genomics · doi:10.1007/s00438-024-02148-z · Cited by 2

Effective leukemia-to-granulocyte induction by a cocktail of RUNX1, SPI1 and CEBPE

Xiang, G., Zhu, P., Zhang, L., Yu, S., Jiang, F., Wang, S., Wang, J., Dai, Y., Wang, S., Tan, Y., et al. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217820 · Cited by 2

Multiomics Signature Reveals Network Regulatory Mechanisms in a CRC Continuum

Higareda‐Almaraz, J. C., Mancuso, F. M., Canal-Noguer, P., Kruusmaa, K., & Bertossi, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157077 · Cited by 2

Lp‑PLA2 in the cancer landscape: From molecular mechanisms to therapeutic potential (Review)

Yang, X., Tu, Y., Liang, N., Li, L., Zhang, J., Xu, J., & Li, C. (2025) · International Journal of Oncology · doi:10.3892/ijo.2025.5793 · Cited by 2

Cell reprogramming in cancer: Interplay of genetic, epigenetic mechanisms, and the tumor microenvironment in carcinogenesis and metastasis

Shenoy, S. (2025) · World Journal of Clinical Oncology · doi:10.5306/wjco.v16.i8.106838 · Cited by 3

Hypersonic levitation and spinning: paving the way for enhanced single-cell analysis via contactless tissue dissociation

Bai, Y., Zheng, Z., Nie, Z., Li, J., Zhang, Z., & Duan, X. (2025) · Communications Engineering · doi:10.1038/s44172-025-00497-0 · Cited by 4

Chromatin looping-based CRISPR screen identifies TLK2 as chromatin loop formation regulator in cancer stemness plasticity

Wang, Z., Liu, F., Chen, N., Wu, J., Li, X., Fang, M., Yan, M., Zhang, J., Deng, B., Wang, L., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64066-x · Cited by 3

p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer

Aylon, Y., Furth, N., Pirona, A. C., Lavie, A., Fedorova, O., Hassin, O., Padrão, N., Steinmetz, M., Sarusi-Portuguez, A., Fellus‐Alyagor, L., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2522646122 · Cited by 2

Multi-omics profiling of ACOX3 unveils pan-cancer clinical biomarker potential

Wang, W.-L., Xiong, Q., Ma, B., Liang, X., & Tang, Y. (2025) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2025.108844 · Cited by 2

Evolution of the MUC1 gene in eutherian mammals as an adaptation responsible for the increasing incidence of cancer in humans

Kufe, D. W. (2026) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2026.189542 · Cited by 3

Synthesis and biological evaluation of bis-triazolyl imidazolium hybrids as anti-breast cancer agents

Aboud, H. K., & Mageed, A. H. (2026) · Pure and Applied Chemistry · doi:10.1515/pac-2026-0765 · Cited by 2

Integrative Computational Approaches to Prostate Cancer with Conditional Reprogramming and AI-Driven Precision Medicine

Fadiel, A., Malpani, P., Eichenbaum, K. D., Naftolin, F. N., Hassouneh, A., Chong, G., & Odunsi, K. O. (2026) · Cells · doi:10.3390/cells15080700 · Cited by 2

Game of clones: decipher lineage plasticity in hormone-driven cancers

Leonita, A., Cheng, S., Warrick, J., Kim, I. Y., Deng, S., & Mu, P. (2026) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-026-06171-8 · Cited by 2

Minimal Residual Disease as a Biological Trait: Rethinking Disease Persistence in Hematologic Malignancies

Caserta, S., Martino, E. A., Vigna, E., Skafi, M., Bruzzese, A., Amodio, N., Lucia, E., D’Arrigo, G., Olivito, V., Labanca, C., et al. (2026) · European Journal Of Haematology · doi:10.1111/ejh.70203 · Cited by 2

Understanding tumor heterogeneity: Implications for precision oncology and therapeutic strategies

Lv, Y., He, C., Xie, Q., Long, F., & Fan, C. (2026) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2026.189617 · Cited by 3

The Signaling Networks of TIM-3, TGF-β, and STING in Glioblastoma

Ahmady, F., Carnie, B. M. H., Anderson, G. E. C., Achari, E., Sharma, A., Achuthan, A. A., Kannourakis, G., & Luwor, R. B. (2026) · Cells · doi:10.3390/cells15110991 · Cited by 2

Face/off: phase-specific modeling of lineage plasticity using near-patient models in genitourinary cancers

Fu, Z., Li, L., Perry, C. J., Ghali, F., Tan, W. S., Kim, I. Y., & Mu, P. (2026) · Gene · doi:10.1016/j.gene.2026.150293 · Cited by 2

The effect of chromatin states on cancer: big data lead the way

Chen, X., & Aifantis, I. (2018) · The Lancet Haematology · doi:10.1016/s2352-3026(18)30066-8 · Cited by 2

L’instabilité génomique, paramètre limitant l’efficacité des thérapies ciblées en oncologie

Billaud, A., Chevalier, L.-M., Campone, M., Morel, A., & Bigot, F. (2020) · Bulletin du Cancer · doi:10.1016/j.bulcan.2020.08.010 · Cited by 3

Metabolic regulation in urological tumors: Interplay with epigenetics and epitranscriptomics

Miranda‐Gonçalves, V., Guimarães‐Teixeira, C., Henrique, R., & Jerónimo, C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85652-2.00019-1 · Cited by 2

Corrupted devolution: How normal cells are reborn as cancer precursors

Lord, A. E., & Ficz, G. (2022) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2022.106263 · Cited by 2

Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model

Boeckelmann, L., Freytag, V., Ahlers, A., Maar, H., Gosau, T., Baranowsky, A., Schmitz, R., Pantel, K., Schumacher, U., Haider, M., et al. (2023) · Bone · doi:10.1016/j.bone.2023.116741 · Cited by 5

Pan‐cancer analysis reveals the pro‐oncogenic role of N6‐methyladenosine (m6A)‐regulated NTMT1 in head and neck squamous cell carcinoma

Zhao, C., Yu, M., & Li, Y. (2023) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23603 · Cited by 2

Polycomb Repressive Complex 2 in Oncology

Guo, Y., Yu, Y., & Wang, G. G. (2023) · Cancer treatment and research · doi:10.1007/978-3-031-45654-1_9 · Cited by 2

Potential of melatonin to reverse epigenetic aberrations in oral cancer: new findings

Gil‐Martín, E., Ramos, E., Lopez-Munoz, F. J., Egea, J., & Romero, A. (2023) · EXCLI journal · doi:10.17179/excli2023-6624 · Cited by 2

miRNA-27a-3p is involved in the plasticity of differentiated hepatocytes

Salerno, D., Peruzzi, G., Pascucci, G. R., Levrero, M., Belloni, L., & Pediconi, N. (2024) · Gene · doi:10.1016/j.gene.2024.148387 · Cited by 2

Potential to use of viral reverse transcriptase inhibitors in oncology

Vlasova, O. A., Antonova, I., Magomedova, K., Usolkina, M. A., Игоревич, К. К., Belitsky, G. A., Valiev, T. T., & Геннадиевна, Я. М. (2024) · Advances in molecular oncology · doi:10.17650/2313-805x-2024-11-2-8-28 · Cited by 2

Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes

Lorenz, L., Zenz, T., Oliinyk, D., Meier-Rosar, F., Jenke, R., Aigner, A. M., & Büch, T. (2024) · Pharmaceuticals · doi:10.3390/ph17081080 · Cited by 2

Single-cell transcriptomics reveals tumor microenvironment remodeling in hepatocellular carcinoma with varying tumor subclonal complexity

Shi, J., Zhang, Y., Xu, L., & Wang, F. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1467682 · Cited by 2

Estimating the Number of Polygenic Diseases Among Six Mutually Exclusive Entities of Non-Tumors and Cancer

Rjh, S., Burger, J. A., & Zain, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252211968 · Cited by 2

Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia

Depies, O. M., Guo, Q., Gao, Y., Sinha, S., Ye, Z., Han, W., Rabe, K. G., Hoel, M. S., Darby, H. C., Yu, C., et al. (2024) · Blood Neoplasia · doi:10.1016/j.bneo.2024.100059 · Cited by 2

A hidden intrinsic ability of bicistronic expression based on a novel translation reinitiation mechanism in yeast

Sun, Y., Bock, R., & Li, Z. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf220 · Cited by 2

Growth factor receptor plasticity drives therapeutic persistence of metastatic breast cancer

Ayers, M. G., Monteiro, M., Kulkarni, A., Reeser, J. W., Dykhuizen, E. C., Roychowdhury, S., & Wendt, M. K. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07591-3 · Cited by 3

RUNX3 Methylation: An Epigenetic Biomarker for Early Liver Damage Induced by Co-Exposure to Aflatoxin B1 and Hepatitis B Virus

Mo, Y., Lu, X., Zheng, S., Deng, J., Huang, S., Ye, H., Xian, X., Yijiati, A., Xia, Y., Luo, X., et al. (2025) · Toxics · doi:10.3390/toxics13060425 · Cited by 2

Multidimensional third-generation sequencing of modified DNA bases allows interrogation of complex biological systems

David, S. S., Pacheco, B. A., Kishimoto, K., Vantine, S. J., Hu, K., Liu, H., Davis, D. L., Tran, H. V., Sallis, B. F., Ali, L. D., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60896-x · Cited by 2

Combining Epigenetic and Immunotherapy in Cancer: Molecular Mechanisms

Meiliana, A., & Wijaya, A. (2023) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v15i1.2062 · Cited by 1

Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis

Feng, L., Vujicic, S., Dietrich, M. E., Litbarg, N. O., Setty, S., Antoni, A., Rauch, J., & Levine, J. S. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra117.001290 · Cited by 2

Applications of Nano-based Novel Drug Delivery Systems in Herbal Medicine-Mediated Cancer Therapy

Srivastava, S., & Pandey, A. (2017) · Springer eBooks · doi:10.1007/978-981-10-8216-0_6 · Cited by 2

Epigenetics in Health and Disease

Cabej, N. R. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814067-3.00014-4 · Cited by 2

Cancer epigenetics in the driver's seat

Kiberstis, P. A. (2017) · Science · doi:10.1126/science.357.6348.263-i · Cited by 1

Epigenetic plasticity, selection, and tumorigenesis

Flavahan, W. A. (2020) · Biochemical Society Transactions · doi:10.1042/bst20191215 · Cited by 31

The Effects of Chromatin and Epigenetics on Cancer and Tumorigenesis

Fischer, P. (2019) · Microreviews in Cell and Molecular Biology

Epigenetics as a mediator of plasticity in cancer

Feinberg, A. P., & Levchenko, A. (2023) · Science · doi:10.1126/science.aaw3835 · Cited by 267

Epigenetic regulation of the cell cycle & DNA-repair in cancer

Tallen, G. R. N., Yang, Y., & Riabowol, K. T. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85679-9.00027-1