Epigenetic plasticity and the hallmarks of cancer

Hallmarks of Cancer: The Next Generation

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The hallmarks of cancer

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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

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Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

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An Integrated Genomic Analysis of Human Glioblastoma Multiforme

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IDH1 and IDH2 Mutations in Gliomas

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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The Epigenomics of Cancer

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EMT: 2016

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Epigenetic Mechanisms in Canine Cancer

Xavier, P. L. P., Müller, S., & Fukumasu, H. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.591843 · Cited by 20

Tissue‐disruption‐induced cellular stochasticity and epigenetic drift: Common origins of aging and cancer?

Capp, J., & Frédéric Thomas, A. (2020) · BioEssays · doi:10.1002/bies.202000140 · Cited by 20

Chromatin Mechanisms Driving CancerPreprint

Gryder, B. E., Scacheri, P. C., Ried, T., & Khan, J. I. (2021) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a040956 · Cited by 20

Update on the Molecular Pathology of Cutaneous Squamous Cell Carcinoma

Cozma, E. C., Banciu, L. M., Soare, C., & Creţoiu, S. M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076646 · Cited by 22

Rapha Myr®, a Blend of Sulforaphane and Myrosinase, Exerts Antitumor and Anoikis-Sensitizing Effects on Human Astrocytoma Cells Modulating Sirtuins and DNA Methylation

Tomasello, B., Mauro, M. D. D., Malfa, G. A., Acquaviva, R., Sinatra, F., Spampinato, G., Laudani, S., Villaggio, G., Bielak-Żmijewska, A., Grabowska, W., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155328 · Cited by 19

Case Report: Low-Dose Decitabine Plus Anti-PD-1 Inhibitor Camrelizumab for Previously Treated Advanced Metastatic Non-Small Cell Lung Cancer

Yan, X., Zhao, Y., Liu, Y., Yang, Q., Dong, L., Wu, Z., Nie, J., Chen, D., Bai, M., Ti, D., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.558572 · Cited by 19

Translocation of intracellular CD24 constitutes a triggering event for drug resistance in breast cancer

Huth, H. W., Castro‐Gomes, T., Goes, A. M., & Ropert, C. (2021) · Scientific Reports · doi:10.1038/s41598-021-96449-7 · Cited by 20

AIRE in context: Leveraging chromatin plasticity to trigger ectopic gene expression*

Kaiser, C., Bradu, A., Gamble, N., Caldwell, J. A., & Koh, A. S. (2021) · Immunological Reviews · doi:10.1111/imr.13026 · Cited by 19

Transcription bursting and epigenetic plasticity: an updated view

Beckman, W. F., Jiménez, M. Á. L., & Verschure, P. J. (2021) · Epigenetics Communications · doi:10.1186/s43682-021-00007-1 · Cited by 22

Transition Therapy: Tackling the Ecology of Tumor Phenotypic Plasticity

Aguadé‐Gorgorió, G., Kauffman, S. A., & Solé, R. V. (2021) · Bulletin of Mathematical Biology · doi:10.1007/s11538-021-00970-9 · Cited by 20

The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKKα and overcomes gefitinib resistance in non-small cell lung cancer

He, T., Gao, Y., Fang, Y., Zhang, Y., Zhang, S., Nan, F., Ding, J., & Chen, Y. (2022) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2021.0130 · Cited by 19

Drug Repurposing Strategies for Non-cancer to Cancer Therapeutics

Singhal, S., Maheshwari, P., Krishnamurthy, P. T., & Patil, V. M. (2022) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520622666220317140557 · Cited by 18

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

Saunus, J. M., Luca, X. M. D., Northwood, K. S., Raghavendra, A., Hasson, A., Reed, A. E. M., Lim, M., Lal, S., Vargas, A. C., Kutasovic, J. R., et al. (2022) · npj Breast Cancer · doi:10.1038/s41523-022-00425-x · Cited by 20

Shared and Divergent Epigenetic Mechanisms in Cachexia and Sarcopenia

Yedigaryan, L., Gatti, M., Marini, V., Maraldi, T., & Sampaolesi, M. (2022) · Cells · doi:10.3390/cells11152293 · Cited by 19

A critical appraisal of clinical epigenetics

Horsthemke, B. (2022) · Clinical Epigenetics · doi:10.1186/s13148-022-01315-6 · Cited by 24

Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Cell and Tissue Structure, Function, and Phenotype

Fritz, A. J., Dika, M. E., Toor, R. H., Rodriguez, P. D., Foley, S. J., Ullah, R., Nie, D., Banerjee, B., Lohese, D., Tracy, K. M., et al. (2022) · Results and problems in cell differentiation · doi:10.1007/978-3-031-06573-6_12 · Cited by 23

Epigenetics and genetics of hepatoblastoma: Linkage and treatment

Zhu, L.-R., Zheng, W., Gao, Q., Chen, T., Pan, Z.-B., Cui, W., Cai, M., & Fang, H. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.1070971 · Cited by 19

Multivalent state transitions shape the intratumoral composition of small cell lung carcinoma

Gopal, P., Petty, A. P., Rogacki, K. R., Bera, T. K., Bareja, R., Peacock, C. D., & Abazeed, M. E. (2022) · Science Advances · doi:10.1126/sciadv.abp8674 · Cited by 20

β-Catenin–Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer

Mohan, D. R., Borges, K. S., Finco, I., LaPensee, C. R., Rege, J., Solon, A. L., Little, D. W., Else, T., Almeida, M. Q., Dang, D., et al. (2023) · Cancer Research · doi:10.1158/0008-5472.can-22-2712 · Cited by 20

MLL1 regulates cytokine-driven cell migration and metastasis

Nair, P. R., Danilova, L., Gómez‐de‐Mariscal, E., Kim, D., Fan, R., Muñoz‐Barrutia, A., Fertig, E. J., & Wirtz, D. (2024) · Science Advances · doi:10.1126/sciadv.adk0785 · Cited by 19

Landscape of active enhancers developed de novo in cirrhosis and conserved in hepatocellular carcinoma.

Yao, Y., Deng, X., Chen, X., Chen, S., Song, L., Meng, M., Han, Q., İmani, S., Li, S., Zhong, Z., et al. (2020) · PubMed Central · Cited by 19

Downregulation of 5‐hydroxymethylcytosine is an early event in pancreatic tumorigenesis

Fujikura, K., Alruwaii, Z. I., Haffner, M. C., Trujillo, M. A. M., Roberts, N. J., Hong, S., Macgregor‐Das, A. M., Goggins, M., Roy, S., Meeker, A. K., et al. (2021) · The Journal of Pathology · doi:10.1002/path.5682 · Cited by 19

The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence

Jenull, S., Mair, T., Tscherner, M., Penninger, P., Zwolanek, F., Silao, F. G. S., Vicente, K. M. D. S., Riedelberger, M., Bandari, N. C., Shivarathri, R., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109406 · Cited by 19

Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis

Liang, Z., Zhang, Y., Zhu, R.-M., Li, Y., Jiang, H., Li, R., Chen, Q.-X., Wang, Q., Tang, L.-Y., & Ren, Z. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-17355-z · Cited by 19

Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells

Shimizu, M., Shibuya, H., & Tanaka, N. (2022) · Scientific Reports · doi:10.1038/s41598-022-06916-y · Cited by 18

Noninvasive Multicancer Detection Using DNA Hypomethylation of LINE-1 Retrotransposons

Michel, M., Heidary, M., Mechri, A., Silva, K. D., Gorse, M., Dixon, V., von Grafenstein, K., Bianchi, C., Hego, C., Rampanou, A., et al. (2024) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-24-2669 · Cited by 20

Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition

East, M. P., & Johnson, G. L. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101525 · Cited by 21

Repeat measures of DNA methylation in an inception cohort of firefighters

Goodrich, J. M., Jung, A. M., Furlong, M., Beitel, S. C., Littau, S. R., Gulotta, J. J., Wallentine, D. D., & Burgess, J. L. (2022) · Occupational and Environmental Medicine · doi:10.1136/oemed-2021-108153 · Cited by 19

Quantification of transcription noise’s impact on cell fate commitment with digital resolutions

Jiao, F., & Tang, M. (2022) · Bioinformatics · doi:10.1093/bioinformatics/btac277 · Cited by 17

METTL3 dual regulation of the stability of LINC00662 and VEGFA RNAs promotes colorectal cancer angiogenesis

Zhang, G., Wang, T., Huang, Z., Chen, Y., Sun, L., Xia, X., He, F., Fan, C., Wang, S., & Liu, W. (2022) · Discover Oncology · doi:10.1007/s12672-022-00557-3 · Cited by 18

Regulation of KDM5C stability and enhancer reprogramming in breast cancer

Xiao, Q., Wang, C., Gao, C., Chen, J., Chen, J., Wang, Z., Ju, L., Tang, S., Yao, J., Feng, L., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05296-5 · Cited by 18

PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression

Hopkins, J., Asada, K., Leung, A., Papadaki, V., Davaapil, H., Morrison, M., Orita, T., Sekido, R., Kosuge, H., Reddy, M. A., et al. (2022) · Cancers · doi:10.3390/cancers14194926 · Cited by 18

MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors

Kim, H., Lebeau, B., Papadopoli, D. J., Jovanović, P., Russo, M. D. S. T., Avizonis, D. Z., Morita, M., Afzali, F., Ursini‐Siegel, J., Postovit, L.-M. M., et al. (2024) · iScience · doi:10.1016/j.isci.2024.109188 · Cited by 17

Clock-dependent chromatin accessibility rhythms regulate circadian transcription

Yuan, Y., Chen, Q., Brovkina, M. V., Clowney, E. J., & Yadlapalli, S. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011278 · Cited by 21

Long non-coding RNA (LncRNA) and epigenetic factors: their role in regulating the adipocytes in bovine

Jilo, D. D., Abebe, B. K., Wang, J., Guo, J., Li, A., & Zan, L. (2024) · Frontiers in Genetics · doi:10.3389/fgene.2024.1405588 · Cited by 18

Acute multi-level response to defective de novo chromatin assembly in S-phase

Dreyer, J., Ricci, G., van den Berg, J., Bhardwaj, V., Funk, J., Armstrong, C., van Batenburg, V., Sine, C. C., VanInsberghe, M. A., Tjeerdsma, R. B., et al. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.10.023 · Cited by 18

3D chromatin hubs as regulatory units of identity and survival in human acute leukemia

Gambi, G., Boccalatte, F. E., Rodriguez-Hernaez, J., Lin, Z., Nadorp, B., Polyzos, A., Tan, J., Avrampou, K., Inghirami, G., Kentsis, A., et al. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.11.040 · Cited by 18

Epigenetic plasticity potentiates a rapid cyclical shift to and from an aggressive cancer phenotype

Xu, T., Li, H., Wei, J., Li, M., Hsieh, T., Lu, Y., Lakshminarasimhan, R., Xu, R., Hodara, E., Morrison, G. J., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.32904 · Cited by 18

Modeling Spontaneous Bone Metastasis Formation of Solid Human Tumor Xenografts in Mice

Labitzky, V., Baranowsky, A., Maar, H., Hanika, S., Starzonek, S., Ahlers, A., Stübke, K., Koziolek, E. J., Heine, M., Schäfer, P., et al. (2020) · Cancers · doi:10.3390/cancers12020385 · Cited by 19

Targeting IDH Mutations in AML: Wielding the Double-edged Sword of Differentiation

Becker, J. S., & Fathi, A. T. (2020) · Current Cancer Drug Targets · doi:10.2174/1568009620666200424145622 · Cited by 18

Causes, effects, and clinical implications of perturbed patterns within the cancer epigenome

Oleksiewicz, U., & Machnik, M. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.12.014 · Cited by 18

DNA methylome and single-cell transcriptome analyses reveal CDA as a potential druggable target for ALK inhibitor–resistant lung cancer therapy

Heo, H., Kim, J.-H., Lim, H. J., Kim, J., Kim, M., Koh, J., Kim, B., Kim, B.-K., Won, M., Park, J.-H., et al. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-022-00836-7 · Cited by 17

A Similar Speciation Process Relying on Cellular Stochasticity in Microbial and Cancer Cell Populations

Capp, J., & Frédéric Thomas, A. (2020) · iScience · doi:10.1016/j.isci.2020.101531 · Cited by 19

Integration of epigenomic and transcriptomic profiling uncovers EZH2 target genes linked to cysteine metabolism in hepatocellular carcinoma

Lee, J., You, C., Kwon, G., Noh, J., Lee, K., Kim, K., Kang, K., & Kang, K. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07198-0 · Cited by 17

A 6-Gene Risk Signature Predicts Survival of Glioblastoma Multiforme

Zhao, J., Wang, L., Hu, G., & Wei, B. (2019) · BioMed Research International · doi:10.1155/2019/1649423 · Cited by 17

Epigenetic aberrations in natural killer/T-cell lymphoma: diagnostic, prognostic and therapeutic implications

Küçük, C., Wang, J., Xiang, Y., & You, H. (2020) · Therapeutic Advances in Medical Oncology · doi:10.1177/1758835919900856 · Cited by 17

Bromodomain and extra-terminal (BET) inhibitors in treating myeloid neoplasms

Chen, N. C., Borthakur, G. M., & Pemmaraju, N. (2020) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2020.1842399 · Cited by 17

Histone H3K27 Methylation Perturbs Transcriptional Robustness and Underpins Dispensability of Highly Conserved Genes in Fungi

Tralamazza, S. M., Abraham, L., Reyes-Avila, C. S., Corrêa, B., & Croll, D. (2021) · Molecular Biology and Evolution · doi:10.1093/molbev/msab323 · Cited by 18

miR-183-5p regulates ECM and EMT to promote non-small cell lung cancer progression by targeting LOXL4

Chen, J., Zhou, D., Liao, H., & Li, Y. (2023) · Journal of Thoracic Disease · doi:10.21037/jtd-23-329 · Cited by 17

N6AMT1 is a novel potential diagnostic, prognostic and immunotherapy response biomarker in pan-cancer

Wang, M., Zhu, J., Ye, Y., Li, P., Sun, W., & Zhang, M. (2023) · Aging · doi:10.18632/aging.204868 · Cited by 17

Regulation of main ncRNAs by polyphenols: A novel anticancer therapeutic approach

Zhang, L., Kang, Q., Kang, M., Jiang, S., Yang, F. W., Gong, J., Ou, G., & Wang, S. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155072 · Cited by 18

METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3

Yi, J., Peng, F., Zhao, J., & Gong, X. (2023) · Scientific Reports · doi:10.1038/s41598-023-44379-x · Cited by 17

Whole-Genome DNA Methylation Profiling of Intrahepatic Cholangiocarcinoma Reveals Prognostic Subtypes with Distinct Biological Drivers

Liao, H., Chen, X., Wang, H., Lin, Y., Chen, L., Yuan, K., Liao, M., Jiang, H., Peng, J., Wu, Z., et al. (2024) · Cancer Research · doi:10.1158/0008-5472.can-23-3298 · Cited by 20

Super-enhancer-driven IRF2BP2 enhances ALK activity and promotes neuroblastoma cell proliferation

Chen, Y., Zhuo, R., Sun, L.-C., Tao, Y., Li, G. L., Zhu, F., Xu, Y., Wang, J., Li, Z., Yu, J., et al. (2024) · Neuro-Oncology · doi:10.1093/neuonc/noae109 · Cited by 18

Prevention of Chromatin Destabilization by FACT Is Crucial for Malignant Transformation

Sandlesh, P., Safina, A. F., Goswami, I., Prendergast, L. A., Rosario, S., Gomez, E. C., Wang, J., & Gurova, K. V. (2020) · iScience · doi:10.1016/j.isci.2020.101177 · Cited by 17

SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer

Shahzad, N., Munir, T., Javed, M., Tasneem, F., Aslam, B., Ali, M., Mutahir, Z., Ali, M. A., Umer, M., Ahmad, M., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236192 · Cited by 17

KDM3A regulates Slug expression to promote the invasion of MCF7 breast cancer cells in hypoxia

Ahn, H.-J., Moon, B., Park, M. J., & Kim, J. (2020) · Oncology Letters · doi:10.3892/ol.2020.12199 · Cited by 17

Integrated RNA Sequencing and Single-Cell Mass Cytometry Reveal a Novel Role of LncRNA HOXA-AS2 in Tumorigenesis and Stemness of Hepatocellular Carcinoma

Lu, Q., Gao, J., Tang, S., Li, Z., Wang, X., Deng, C., Hu, J., Tao, Y., & Wang, Q. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s272717 · Cited by 17

A Novel Approach for Calculating Exact Forms of mRNA Distribution in Single-Cell Measurements

Chen, J., & Jiao, F. (2021) · Mathematics · doi:10.3390/math10010027 · Cited by 16

Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

Ang, D. A., Carter, J.-M., Deka, K., Tan, J. H. L., Zhou, J., Chen, Q., Chng, W. J., Harmston, N., & Li, Y. (2024) · Nature Communications · doi:10.1038/s41467-024-46728-4 · Cited by 13

Construction and Validation of a Potent Epigenetic Modification-Related Prognostic Signature for Osteosarcoma Patients

Liu, S., Wu, B., Li, X., Zhao, L., Wu, W., & Ai, S. (2021) · Journal of Oncology · doi:10.1155/2021/2719172 · Cited by 15

Old drugs, new challenges: reassigning drugs for cancer therapies

Czechowicz, P., Więch, A., Sławski, J., Collawn, J. F., & Bartoszewski, R. (2025) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-025-00710-0 · Cited by 19

Exploring the mechanisms of mutual influence between lactylation and macrophage polarization in the context of disease

Guo, H., Luan, N., Gao, J., Pang, X., Bi, J., & Zhu, L. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70499 · Cited by 20

The Role of the Histone Methyltransferase PfSET10 in Antigenic Variation by Malaria Parasites: a Cautionary Tale

Ngwa, C. J., Gross, M., Musabyimana, J.-P., Pradel, G., & Deitsch, K. (2021) · mSphere · doi:10.1128/msphere.01217-20 · Cited by 16

Toxicoepigenetics and Environmental Health: Challenges and Opportunities

Svoboda, L. K., Perera, B. P. U., Morgan, R. K., Polemi, K. M., Pan, J., & Dolinoy, D. C. (2022) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.1c00445 · Cited by 17

H3K27 acetylation activated long noncoding RNA RP11-162G10.5 promotes breast cancer progression via the YBX1/GLO1 axis

Xie, N., Zhang, R., Bi, Z., Ren, W., You, K., Hu, H., Xu, Y. X., & Yao, H. (2022) · Cellular Oncology · doi:10.1007/s13402-022-00756-8 · Cited by 16

Chromatin complex dependencies reveal targeting opportunities in leukemia

Najm, F. J., DeWeirdt, P. C., Moore, M. M., Bevill, S. M., Farran, C. A. E., Macias, K. A., Hegde, M., Waterbury, A. L., Liau, B. B., van Galen, P., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36150-7 · Cited by 16

Getting personal with epigenetics: towards individual-specific epigenomic imputation with machine learning

Hawkins‐Hooker, A., Visonà, G., Narendra, T., Rojas-Carulla, M., Schölkopf, B., & Schweikert, G. (2023) · Nature Communications · doi:10.1038/s41467-023-40211-2 · Cited by 19

Decoding Cancer Evolution: Integrating Genetic and Non-Genetic Insights

Ashouri, A., Zhang, C., & Gaiti, F. (2023) · Genes · doi:10.3390/genes14101856 · Cited by 17

Crosstalk between bladder cancer and the tumor microenvironment: Molecular mechanisms and targeted therapy

Lu, X., Liang Cheng, C., Yang, C., Huang, J., & Chen, X. (2024) · The Innovation Medicine · doi:10.59717/j.xinn-med.2024.100094 · Cited by 17

Oncogenic IDH1 mut drives robust loss of histone acetylation and increases chromatin heterogeneity

Furth, N., Cohen, N., Spitzer, A., Salame, T., Dassa, B., Mehlman, T., Brandis, A. S., Moussaieff, A., Friedmann‐Morvinski, D., Castro, M. G., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2403862122 · Cited by 17

Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue

Becker, L., Nogueira, M. S., Klima, C., de Angelis, M. H., & Peleg, S. (2018) · Scientific Reports · doi:10.1038/s41598-018-22674-2 · Cited by 16

Regulation of epigenetic state by non-histone chromatin proteins and transcription factors: Implications in disease

Sikder, S., Kaypee, S., & Kundu, T. K. (2020) · Journal of Biosciences · doi:10.1007/s12038-019-9974-3 · Cited by 17

Stochastic epigenetic dynamics of gene switching

Bhattacharyya, B., Wang, J., & Sasai, M. (2020) · Physical review. E · doi:10.1103/physreve.102.042408 · Cited by 15

High levels of global genome methylation in patients with retinoblastoma

Yazıcı, H., Wu, H., Tigli, H., Yilmaz, E., Kebudi, R., & Santella, R. M. (2020) · Oncology Letters · doi:10.3892/ol.2020.11613 · Cited by 16

Bromodomain protein BRD4 is an epigenetic activator of B7-H6 expression in acute myeloid leukemia

Raneros, A. B., Rodríguez, R. M. A., Flórez, A. B., Palomo, P., Colado, E., Minguela, A., Suárez-Álvarez, B., & López‐Larrea, C. (2021) · OncoImmunology · doi:10.1080/2162402x.2021.1897294 · Cited by 16

Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis

Karlow, J. A., Miao, B., Xing, X., Wang, T., & Zhang, B. (2021) · Communications Biology · doi:10.1038/s42003-021-02094-1 · Cited by 17

Advances in Multi-Omics Applications in HBV-Associated Hepatocellular Carcinoma

Cui, D., Li, W., Jiang, D., Wu, J., Xie, J., & Wu, Y. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.754709 · Cited by 17

Clonal Selection and Evolution of HTLV-1-Infected Cells Driven by Genetic and Epigenetic Alteration

Yamagishi, M., Suzuki, Y., Watanabe, T., & Uchimaru, K. (2022) · Viruses · doi:10.3390/v14030587 · Cited by 16

DNA methylation dynamic of bone marrow hematopoietic stem cells after allogeneic transplantation

Trino, S., Zoppoli, P., Carella, A. M., Laurenzana, I., Weisz, A., Memoli, D., Calice, G., Rocca, F. L., Simeon, V., Savino, L., et al. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1245-6 · Cited by 16

Direct monitoring of breast and endometrial cancer cell epigenetic response to DNA methyltransferase and histone deacetylase inhibitors

Teixeira, S. R., Abreu, C. M., Parkes, L., Davies, J., Yao, S. N., Sawhney, M. A., Margarit, L., González, D., Pinto, I. M., Francis, L. W., et al. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.111386 · Cited by 16

Differences in mutational processes and intra-tumour heterogeneity between organs

Giraudeau, M., Sepp, T., Újvári, B., Renaud, F., Tasiemski, A., Roche, B., Capp, J., & Frédéric Thomas, A. (2019) · Evolution Medicine and Public Health · doi:10.1093/emph/eoz017 · Cited by 16

Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia

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Combinatorial Epigenetic and Immunotherapy in Breast Cancer Management: A Literature Review

Lee, Y.-T., Chuang, Y., & Chan, M. W. Y. (2020) · Epigenomes · doi:10.3390/epigenomes4040027 · Cited by 18

Epigenetic and transcriptional profiling of triple negative breast cancer

Perreault, A. A., Sprunger, D. M., & Venters, B. J. (2019) · Scientific Data · doi:10.1038/sdata.2019.33 · Cited by 16

Senescence-associated lineage-aberrant plasticity evokes T-cell-mediated tumor control

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Hepatitis B-Induced Hepatocellular Carcinoma: Understanding Viral Carcinogenesis and Disease Management

Farbod, Y., Kankouni, H., Moini, M., & Fung, S. K. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14072505 · Cited by 15

NIR‐II Type I Photosensitizer for Efficient Cancer Therapy Through Synergistic Ferroptosis/Pyroptosis Induction and Mitophagy Inhibition

Zhuang, J., Song, S., Yang, L., Pan, Q., He, Y., Huo, L., Li, N., & Zhao, N. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202501346 · Cited by 15

CRISPR/Cas technologies in pancreatic cancer research and therapeutics: recent advances and future outlook

Noormohamadi, H., Samarkhazan, H. S., Kargar, M., Maroufi, F., Servatian, N., & Davami, F. (2025) · Discover Oncology · doi:10.1007/s12672-025-03383-5 · Cited by 17

Persistent lineage plasticity driving lung cancer development and progression

Meng, F., Li, J., Xia, Z., Wang, Q., Sun, Q., Wang, S., Xu, L., & Yin, R. H. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70458 · Cited by 17

Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology

Salazar, C., Yáñez, O., Elorza, Á. A., Cortés, N., García‐Beltrán, O., Tiznado, W., & Ruíz, L. M. (2020) · Genes · doi:10.3390/genes11020206 · Cited by 14

Base-Resolution Analysis of Deoxyuridine at the Genome Scale Based on the Artificial Incorporation Modified Nucleobase

Wang, Y., Zhang, X., Han, S., Yang, W., Chen, Z., Wu, F., Liu, J., Weng, X., & Zhou, X. (2021) · ACS Central Science · doi:10.1021/acscentsci.0c01504 · Cited by 15

Delineating the longitudinal tumor evolution using organoid models

Lu, Z., Nie, B., Zhai, W., & Hu, Z. (2021) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2021.06.010 · Cited by 15

Therapeutic Targeting of Cancer: Epigenetic Homeostasis

Yu, X., Li, M., Guo, C., Wu, Y., Zhao, L., Shi, Q., Song, J., & Song, B. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.747022 · Cited by 15

LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle

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Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma

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Statistical inference of the rates of cell proliferation and phenotypic switching in cancer

Gunnarsson, E. B., Foo, J., & Leder, K. (2022) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2023.111497 · Cited by 15

Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice

Stephens, G. S., Park, J. K., Eagle, A. L., You, J. C., Silva‐Pérez, M., Fu, C.-H., Choi, S., Romain, C. P. S., Sugimoto, C., Buffington, S. A., et al. (2024) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2024.102612 · Cited by 16

Targeting DNA Methylation Machinery in Pediatric Solid Tumors

Cristalli, C., & Scotlandi, K. (2024) · Cells · doi:10.3390/cells13141209 · Cited by 14

A different methylation profile of circadian genes promoter in breast cancer patients according to clinicopathological features

Lesicka, M., Jabłońska, E., Wieczorek, E., Seroczyńska, B., Kalinowski, L., Skokowski, J., & Reszka, E. (2019) · Chronobiology International · doi:10.1080/07420528.2019.1617732 · Cited by 15

Cancer epigenetics in the driver's seat

Kiberstis, P. A. (2017) · Science · doi:10.1126/science.357.6348.263-i · Cited by 1

Epigenetic plasticity, selection, and tumorigenesis

Flavahan, W. A. (2020) · Biochemical Society Transactions · doi:10.1042/bst20191215 · Cited by 31

The Effects of Chromatin and Epigenetics on Cancer and Tumorigenesis

Fischer, P. (2019) · Microreviews in Cell and Molecular Biology

Epigenetics as a mediator of plasticity in cancer

Feinberg, A. P., & Levchenko, A. (2023) · Science · doi:10.1126/science.aaw3835 · Cited by 267

Epigenetic regulation of the cell cycle & DNA-repair in cancer

Tallen, G. R. N., Yang, Y., & Riabowol, K. T. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85679-9.00027-1