Epigenetic plasticity and the hallmarks of cancer

Hallmarks of Cancer: The Next Generation

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The hallmarks of cancer

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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Rao, S. S. P., Huntley, M. H., Durand, N. C., Stamenova, E. K., Bochkov, I. D., Robinson, J. T., Sanborn, A. L., Machol, I., Omer, A. D., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.021 · Cited by 9,212

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

Jones, P. A. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3230 · Cited by 6,061

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

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IDH1 and IDH2 Mutations in Gliomas

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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The Epigenomics of Cancer

Jones, P. A., & Baylin, S. B. (2007) · Cell · doi:10.1016/j.cell.2007.01.029 · Cited by 4,515

EMT: 2016

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Epigenetic modifications of autophagy in cancer and cancer therapeutics

Bhol, C. S., Panigrahi, D. P., Praharaj, P. P., Mahapatra, K. K., Patra, S., Mishra, S. R., Behera, B. P., & Bhutia, S. K. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.05.020 · Cited by 67

Understanding the role of phenotypic switching in cancer drug resistance

Gunnarsson, E. B., De, S., Leder, K., & Foo, J. (2020) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2020.110162 · Cited by 68

The Spatial and Genomic Hierarchy of Tumor Ecosystems Revealed by Single-Cell Technologies

Smith, E. A., & Hodges, H. C. (2019) · Trends in cancer · doi:10.1016/j.trecan.2019.05.009 · Cited by 61

Hexokinase 2 discerns a novel circulating tumor cell population associated with poor prognosis in lung cancer patients

Liu, Y., Yan, X. S., Chen, J., Zhan, Q., Hua, Y., Xu, S., Li, Z., Wang, Z., Dong, Y., Zuo, D., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2012228118 · Cited by 64

Epithelial–Mesenchymal Transition Signaling and Prostate Cancer Stem Cells: Emerging Biomarkers and Opportunities for Precision Therapeutics

Chaves, L. P., Melo, C. M., Saggioro, F. P., dos Reis, R. B., & Squire, J. A. (2021) · Genes · doi:10.3390/genes12121900 · Cited by 66

Tumorigenicity risk of iPSCs in vivo: nip it in the bud

Zhong, C., Liu, M., Pan, X., & Zhu, H. (2022) · Precision Clinical Medicine · doi:10.1093/pcmedi/pbac004 · Cited by 69

Technologies and applications of single-cell DNA methylation sequencing

Liu, F., Wang, Y., Gu, H., & Wang, X. (2023) · Theranostics · doi:10.7150/thno.82582 · Cited by 64

Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression

Crispo, F., Condelli, V., Lepore, S., Notarangelo, T., Sgambato, A., Esposito, F., Maddalena, F., & Landriscina, M. (2019) · Cells · doi:10.3390/cells8080798 · Cited by 63

A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion

Cai, X.-C., Zhang, T., Kim, E., Jiang, M. Z., Wang, K., Wang, J., Chen, S., Zhang, N., Wu, H., Li, F., et al. (2019) · eLife · doi:10.7554/elife.47110 · Cited by 62

Sentinels of chromatin: chromodomain helicase DNA-binding proteins in development and diseasePreprint

Alendar, A., & Berns, A. J. M. (2021) · Genes & Development · doi:10.1101/gad.348897.121 · Cited by 69

Effects of Lignin-Based Hollow Nanoparticle Structure on the Loading and Release Behavior of Doxorubicin

Zhou, Y., Han, Y., Li, G., & Chu, F. (2019) · Materials · doi:10.3390/ma12101694 · Cited by 63

LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma

Leiendecker, L., Jung, P. S., Kręcioch, I., Neumann, T., Schleiffer, A., Mechtler, K., Wiesner, T., & Obenauf, A. C. (2020) · EMBO Molecular Medicine · doi:10.15252/emmm.202012525 · Cited by 65

Malignant JAK-signaling: at the interface of inflammation and malignant transformation

Perner, F., Pahl, H. L., Zeiser, R., & Heidel, F. H. (2025) · Leukemia · doi:10.1038/s41375-025-02569-8 · Cited by 71

Epigenetic landscape of small cell lung cancer: small image of a giant recalcitrant disease

Κhan, P., Siddiqui, J. A., Maurya, S. K., Lakshmanan, I., Jain, M., Ganti, A. K., Salgia, R., Batra, S. K., & Nasser, M. W. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.11.006 · Cited by 64

Identification of Platform-Independent Diagnostic Biomarker Panel for Hepatocellular Carcinoma Using Large-Scale Transcriptomics Data

Kaur, H., Dhall, A., Kumar, R., & Raghava, G. P. S. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2019.01306 · Cited by 61

Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death

Cottone, L., Cribbs, A. P., Khandelwal, G., Wells, G., Ligammari, L., Philpott, M., Tumber, A., Lombard, P., Hookway, E. S., Szommer, T., et al. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-1387 · Cited by 60

Methylation classifiers: Brain tumors, sarcomas, and what's next

Koelsche, C., & von Deimling, A. (2022) · Genes Chromosomes and Cancer · doi:10.1002/gcc.23041 · Cited by 62

Epigenetic frontiers: miRNAs, long non-coding RNAs and nanomaterials are pioneering to cancer therapy

Prabhakaran, R., Thamarai, R., Sivasamy, S., Dhandayuthapani, S., Batra, J., Kamaraj, C., Karthik, K., Shah, M. A., & Mallik, S. (2024) · Epigenetics & Chromatin · doi:10.1186/s13072-024-00554-6 · Cited by 70

WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastomaPreprint

Mitchell, K., Sprowls, S. A., Arora, S., Shakya, S., Silver, D. J., Goins, C. M., Wallace, L. C., Roversi, G. A., Schafer, R., Kay, K. E., et al. (2023) · Genes & Development · doi:10.1101/gad.349803.122 · Cited by 62

HBx Protein Contributes to Liver Carcinogenesis by H3K4me3 Modification Through Stabilizing WD Repeat Domain 5 Protein

Gao, W., Jia, Z., Tian, Y., Yang, P., Sun, H., Wang, C., Ding, Y., Zhang, M., Zhang, Y., Yang, D., et al. (2019) · Hepatology · doi:10.1002/hep.30947 · Cited by 60

Regulating Methylation at H3K27: A Trick or Treat for Cancer Cell Plasticity

Das, P., & Taube, J. H. (2020) · Cancers · doi:10.3390/cancers12102792 · Cited by 61

The Bidirectional Relationship Between Cancer Epigenetics and Metabolism

Izzo, L., Affronti, H. C., & Wellen, K. E. (2020) · Annual Review of Cancer Biology · doi:10.1146/annurev-cancerbio-070820-035832 · Cited by 64

Precision Oncology Beyond Genomics: The Future Is Here—It Is Just Not Evenly Distributed

Pfohl, U., Pflaume, A., Regenbrecht, M., Finkler, S., Adelmann, Q. G., Reinhard, C., Regenbrecht, C. R. A., & Wedeken, L. (2021) · Cells · doi:10.3390/cells10040928 · Cited by 68

Exploitation of Apoptotic Regulation in Cancer

Ucker, D. S., & Levine, J. S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00241 · Cited by 79

The dynamic conformational landscape of the protein methyltransferase SETD8

Chen, S., Wiewiora, R., Meng, F., Babault, N., Ma, A., Yu, W., Qian, K., Hu, H., Zou, H., Wang, J., et al. (2019) · eLife · doi:10.7554/elife.45403 · Cited by 54

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis

Tricarico, R., Nicolas, É., Hall, M. J., & Golemis, E. A. (2020) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-1741 · Cited by 62

Targeted demethylation of the SARI promotor impairs colon tumour growth

Wang, Q., Dai, L., Wang, Y., Deng, J. V., Lin, Y., Wang, Q., Fang, C., Ma, Z., Wang, H., Shi, G., et al. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.01.040 · Cited by 58

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas

Harpaz, N., Mittelman, T., Beresh, O., Griess, O., Furth, N., Salame, T., Oren, R., Fellus‐Alyagor, L., Harmelin, A., Alexandrescu, S., et al. (2022) · Molecular Cell · doi:10.1016/j.molcel.2022.05.023 · Cited by 61

Advances of Epigenetic Biomarkers and Epigenome Editing for Early Diagnosis in Breast Cancer

Sarvari, P., Sarvari, P., Ramírez‐Díaz, I., Mahjoubi, F., & Rubio, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179521 · Cited by 68

Single-cell multi-omics sequencing uncovers region-specific plasticity of glioblastoma for complementary therapeutic targeting

Wang, X., Sun, Q., Liu, T., Lu, H., Lin, X., Wang, W., Liu, Y., Huang, Y., Huang, G., Sun, H., et al. (2024) · Science Advances · doi:10.1126/sciadv.adn4306 · Cited by 65

Natural antisense transcripts in the biological hallmarks of cancer: powerful regulators hidden in the dark

Zhao, S., Zhang, X., Chen, S., & Zhang, S. (2020) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01700-0 · Cited by 59

Histone Variants: Guardians of Genome Integrity

Ferrand, J., Rondinelli, B., & Polo, S. E. (2020) · Cells · doi:10.3390/cells9112424 · Cited by 63

Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk lociPreprint

Hong, T., Parameswaran, S., Donmez, O. A., Miller, D., Forney, C. R., Lape, M., Ribeiro, M. S. J., Liang, J., Edsall, L., Magnusen, A. F., et al. (2021) · Genome Research · doi:10.1101/gr.264705.120 · Cited by 57

Dynamic reversal of random X-Chromosome inactivation during iPSC reprogrammingPreprint

Janiszewski, A., Talón, I., Chappell, J., Collombet, S., Song, J., Geest, N. D., To, S. K., Bervoets, G., Marín-Béjar, O., Provenzano, C., et al. (2019) · Genome Research · doi:10.1101/gr.249706.119 · Cited by 53

Using What We Already Have: Uncovering New Drug Repurposing Strategies in Existing Omics Data

Pulley, J. M., Rhoads, J. P., Jerome, R. N., Challa, A. P., Erreger, K., Joly, M. M., Lavieri, R. R., Perry, K. E., Zaleski, N. M., Shirey-Rice, J. K., et al. (2019) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010919-023537 · Cited by 59

Loss of KMT5C Promotes EGFR Inhibitor Resistance in NSCLC via LINC01510-Mediated Upregulation of MET

Pal, A. S., Agredo, A., Lanman, N. A., Son, J., Sohal, I. S., Bains, M., Li, C., Clingerman, J., Gates, K., & Kasinski, A. L. (2022) · Cancer Research · doi:10.1158/0008-5472.can-20-0821 · Cited by 57

Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling

Nguyen, K. B., & Spranger, S. (2019) · The Journal of Cell Biology · doi:10.1083/jcb.201908224 · Cited by 55

Leveraging Single-Cell Approaches in Cancer Precision Medicine

Nath, A., & Bild, A. (2021) · Trends in cancer · doi:10.1016/j.trecan.2021.01.007 · Cited by 57

CENP-A overexpression promotes distinct fates in human cells, depending on p53 status

Jeffery, D., Gatto, A., Podsypanina, K., Renaud-Pageot, C., Landete, R. P., Bonneville, L., Dumont, M., Fachinetti, D., & Almouzni, G. (2021) · Communications Biology · doi:10.1038/s42003-021-01941-5 · Cited by 57

RNA Modifications: Reversal Mechanisms and Cancer

Thapar, R., Bacolla, A., Oyeniran, C., Brickner, J. R., Chinnam, N. B., Mosammaparast, N., & Tainer, J. A. (2018) · Biochemistry · doi:10.1021/acs.biochem.8b00949 · Cited by 54

Metabolic regulation of prostate cancer heterogeneity and plasticity

Peitzsch, C., Gorodetska, I., Klusa, D., Shi, Q., Alves, T. C., Pantel, K., & Dubrovska, A. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.12.002 · Cited by 54

Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy

Xiao, W., Zhou, Q., Wen, X., Wang, R., Liu, R., Wang, T., Shi, J., Hu, Y., & Hou, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.702360 · Cited by 51

Prognostic value of circulating tumour DNA in metastatic pancreatic cancer patients: post-hoc analyses of two clinical trials

Pietrasz, D., Renault, S., Taı̈eb, J., Dahan, L., Postel, M., Durand-Labrunie, J., Malicot, K. L., Mulot, C., Rinaldi, Y., Phelip, J., et al. (2021) · British Journal of Cancer · doi:10.1038/s41416-021-01624-2 · Cited by 56

Integration of multi-omics approaches in exploring intra-tumoral heterogeneity

Dong, M., Wang, L., Hu, N., Rao, Y., Wang, Z., & Zhang, Y. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03944-2 · Cited by 57

Machine Learning for Nuclear Mechano-Morphometric Biomarkers in Cancer Diagnosis

Radhakrishnan, A., Damodaran, K., Soylemezoglu, A. C., Uhler, C., & Shivashankar, G. V. (2017) · Scientific Reports · doi:10.1038/s41598-017-17858-1 · Cited by 51

Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma

Frede, J., Anand, P., Sotudeh, N., Pinto, R. A., Nair, M. S., Stuart, H., Yee, A. J., Vijaykumar, T., Waldschmidt, J. M., Potdar, S. V., et al. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00766-y · Cited by 55

Arid1a restrains Kras-dependent changes in acinar cell identity

Livshits, G., Alonso-Curbelo, D., Morris, J. P., Koche, R., Saborowski, M., Wilkinson, J. E., & Lowe, S. W. (2018) · eLife · doi:10.7554/elife.35216 · Cited by 48

Epigenetic Biomarkers for the Diagnosis and Treatment of Liver Disease

Arechederra, M., Recalde, M., Gárate‐Rascón, M., Fernández‐Barrena, M. G., Avila, M. A., & Berasain, C. (2021) · Cancers · doi:10.3390/cancers13061265 · Cited by 54

SLC7A2 deficiency promotes hepatocellular carcinoma progression by enhancing recruitment of myeloid-derived suppressors cells

Xia, S., Wu, J., Zhou, W., Zhang, M., Zhao, K., Liu, J., Tian, D., & Liao, J. (2021) · Cell Death and Disease · doi:10.1038/s41419-021-03853-y · Cited by 54

Reviewing cancer’s biology: an eclectic approach

DIORI, I. K., & Şanlıer, Ş. H. (2021) · Journal of the Egyptian National Cancer Institute · doi:10.1186/s43046-021-00088-y · Cited by 54

Risk Factors for Childhood Leukemia: Radiation and Beyond

Schmidt, J.-A., Hornhardt, S., Erdmann, F., Sánchez-García, I., Fischer, U., Schüz, J., & Ziegelberger, G. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.805757 · Cited by 61

Acute lymphoblastic leukemia displays a distinct highly methylated genome

Hetzel, S., Mattei, A. L., Kretzmer, H., Qu, C., Chen, X. '., Fan, Y., Wu, G., Roberts, K. G., Luger, S. M., Litzow, M. R., et al. (2022) · Nature Cancer · doi:10.1038/s43018-022-00370-5 · Cited by 52

Epigenetic and long-term effects of nicotine on biology, behavior, and health

Gould, T. J. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106741 · Cited by 59

Metabolic regulation of epigenetic remodeling in immune cells

Britt, E. C., John, S. V., Locasale, J. W., & Fan, J. (2020) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2019.12.008 · Cited by 54

3D chromatin architecture and epigenetic regulation in cancer stem cells

Feng, Y., Liu, X., & Pauklin, S. (2021) · Protein & Cell · doi:10.1007/s13238-020-00819-2 · Cited by 55

H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape

Furth, N., Algranati, D., Dassa, B., Beresh, O., Fedyuk, V., Morris, N., Kasper, L. H., Jones, D. R., Monje, M., Baker, S. J., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110836 · Cited by 52

Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities

Ho, S. W. T., Sheng, T., Xing, M., Ooi, W. F., Xu, C., Sundar, R., Huang, K. K., Li, Z., Kumar, V., Ramnarayanan, K., et al. (2022) · Gut · doi:10.1136/gutjnl-2021-326483 · Cited by 51

Impaired histone inheritance promotes tumor progression

Tian, C., Zhou, J., Li, X., Gao, Y., Wen, Q., Kang, X., Wang, N., Yao, Y., Jiang, J., Song, G., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-39185-y · Cited by 49

HTLV-1-Mediated Epigenetic Pathway to Adult T-Cell Leukemia–Lymphoma

Yamagishi, M., Fujikawa, D., Watanabe, T., & Uchimaru, K. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01686 · Cited by 51

Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance

Lü, Y., Bintz, M., Yang, Y., Robert, L., Ng, A. H. C., Liu, V., Ribas, A., Heath, J. R., & Wei, W. (2019) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1007034 · Cited by 49

Review on the Role of Epigenetic Modifications in Doxorubicin-Induced Cardiotoxicity

Kumari, H., Huang, W.-H., & Chan, M. W. Y. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.00056 · Cited by 51

G9a regulates tumorigenicity and stemness through genome-wide DNA methylation reprogramming in non-small cell lung cancer

Pangeni, R. P., Yang, L., Zhang, K., Wang, J., Li, W., Guo, C., Yun, X., Sun, T., Wang, J., & Raz, D. J. (2020) · Clinical Epigenetics · doi:10.1186/s13148-020-00879-5 · Cited by 52

m6A-modified circFNDC3B inhibits colorectal cancer stemness and metastasis via RNF41-dependent ASB6 degradation

Zeng, W., Zhu, J.-F., Guo, J., Huang, G., Ai, L.-S., Zeng, Y., & Liao, W. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05451-y · Cited by 50

Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications

Grasso, G., Colella, F., Forciniti, S., Onesto, V., Iuele, H., Siciliano, A. C., Carnevali, F., Chandra, A., Gigli, G., & del Mercato, L. L. (2023) · Nanoscale Advances · doi:10.1039/d3na00218g · Cited by 52

Targeting metabolic-epigenetic-immune axis in cancer: molecular mechanisms and therapeutic implications

Wang, X., Luo, X., Xiao, R., Liu, X., Zhou, F., Jiang, D., Bai, J., Cui, M., You, L., & Yupei, Z. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02334-4 · Cited by 59

The Epigenetic Landscape of Vascular Calcification: An Integrative Perspective

Hou, Y., Lu, C., Yuan, T., Liao, M.-T., Chao, C., & Lu, K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030980 · Cited by 50

Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics

Li, Z., Wang, Z., Tang, Y., Lu, X., Chen, J., Dong, Y., Wu, B., Wang, C., Liu, Y., Guo, Z., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11808-3 · Cited by 48

Epigenetic mechanisms influencing COVID-19

Sen, R., Garbati, M. R., Bryant, K. F., & Lu, Y. (2021) · Genome · doi:10.1139/gen-2020-0135 · Cited by 49

CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma

Hu, F., Chen, H., Duan, Y., Lan, B., Liu, C., Hu, H., Xu, D., Zhang, Q., Cheng, Y., Liu, M., et al. (2021) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2021.12.032 · Cited by 49

Epigenetic remodeling of the immune landscape in cancer: therapeutic hurdles and opportunities

Tien, F., Lu, H., Lin, S., & Tsai, H.-C. (2023) · Journal of Biomedical Science · doi:10.1186/s12929-022-00893-0 · Cited by 51

scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer

Huang, C., Liu, Z., Guo, Y., Wang, W., Yuan, Z., Guan, Y., Pan, D., Hu, Z., Sun, L., Fu, Z., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae1100 · Cited by 53

Hypermethylation of SHISA3 Promotes Nasopharyngeal Carcinoma Metastasis by Reducing SGSM1 Stability

Zhang, J., Li, Y.-Q., Guo, R., Wang, Y., Zhang, P., Tang, X.-R., Wen, X., Hong, X.-H., Lei, Y., He, Q.-M., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-1754 · Cited by 49

Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation

Miranda‐Gonçalves, V., Lameirinhas, A., Macedo‐Silva, C., Lobo, J., Dias, P. C., Ferreira, V., Henrique, R., & Jerónimo, C. (2020) · Cells · doi:10.3390/cells9041053 · Cited by 48

Chromatin accessibility analysis reveals that TFAP2A promotes angiogenesis in acquired resistance to anlotinib in lung cancer cells

Zhang, L., Lü, J., Liu, R., Hu, M., Zhao, Y., Tan, S. H., Wang, S.-Y., Zhang, B., Nie, W., Dong, Y., et al. (2020) · Acta Pharmacologica Sinica · doi:10.1038/s41401-020-0421-7 · Cited by 48

The HOTAIR lncRNA: A remarkable oncogenic promoter in human cancer metastasis (Review)

Chen, L., Qian, X., Wang, Z., & Zhou, X. (2021) · Oncology Letters · doi:10.3892/ol.2021.12563 · Cited by 51

Cellular and Molecular Mechanisms Modulated by Genistein in Cancer

Naponelli, V., Piscazzi, A., & Mangieri, D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031114 · Cited by 51

Epigenetic Modifications in Tumor-Associated Macrophages: A New Perspective for an Old Foe

Niu, Y., Chen, J., & Qiao, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.836223 · Cited by 49

HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation

Chia, L., Wang, B., Kim, J., Luo, L., Shuai, S., Herrera, I., Chen, S. Y., Li, L., Xian, L., Huso, T. H., et al. (2023) · Journal of Clinical Investigation · doi:10.1172/jci151601 · Cited by 52

Epigenetic regulation of neuroblastoma development

Durinck, K., & Speleman, F. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2773-y · Cited by 47

Stem cell quiescence and its clinical relevance

Luo, M., Li, J.-F., Yang, Q., Zhang, K., Wang, Z., Zheng, S. S., & Zhou, J. (2020) · World Journal of Stem Cells · doi:10.4252/wjsc.v12.i11.1307 · Cited by 48

HDAC7-mediated control of tumour microenvironment maintains proliferative and stemness competence of human mammary epithelial cells

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Gastrointestinal Cancer Patient Nutritional Management: From Specific Needs to Novel Epigenetic Dietary Approaches

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