Epigenetic plasticity and the hallmarks of cancer

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590

The hallmarks of cancer

Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

Rao, S. S. P., Huntley, M. H., Durand, N. C., Stamenova, E. K., Bochkov, I. D., Robinson, J. T., Sanborn, A. L., Machol, I., Omer, A. D., Lander, E. S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.11.021 · Cited by 9,212

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,951

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Jones, P. A. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3230 · Cited by 6,061

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

Parsons, D. W., Jones, S., Zhang, X., Lin, J. C.-H., Leary, R. J., Angenendt, P., Mankoo, P., Carter, H., Siu, I.-M., Gallia, G. L., et al. (2008) · Science · doi:10.1126/science.1164382 · Cited by 5,857

IDH1 and IDH2 Mutations in Gliomas

Yan, H., Parsons, D. W., Jin, G., McLendon, R., Rasheed, B. A., Yuan, W., Kos, I., Batinic-Haberle, I., Jones, S., Riggins, G. J., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808710 · Cited by 5,847

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B., Meissner, A., Wernig, M., Plath, K., et al. (2006) · Cell · doi:10.1016/j.cell.2006.02.041 · Cited by 5,361

The Epigenomics of Cancer

Jones, P. A., & Baylin, S. B. (2007) · Cell · doi:10.1016/j.cell.2007.01.029 · Cited by 4,515

EMT: 2016

Nieto, M. A., Huang, R. Y.-J., Jackson, R. A., & Thiery, J. P. (2016) · Cell · doi:10.1016/j.cell.2016.06.028 · Cited by 4,492

Inhibition of demethylase by IOX1 modulates chromatin accessibility to enhance NSCLC radiation sensitivity through attenuated PIF1

Li, Q., Qin, K., Tian, Y., Chen, B., Zhao, G., Xu, S., & Wu, L. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06346-2 · Cited by 7

Epigenetic Inheritance From Normal Origin Cells Can Determine the Aggressive Biology of Tumor-Initiating Cells and Tumor Heterogeneity

Ji-liang, F., Zhao, D., Lv, F., & Yuan, Z. (2022) · Cancer Control · doi:10.1177/10732748221078160 · Cited by 7

Development and Validation of a Novel Prognostic Model for Lower-Grade Glioma Based on Enhancer RNA-Regulated Prognostic Genes

Tian, W., Yan, G., Chen, K., Han, X., Zhang, W., Sun, L., Zhang, Q., Zhang, Y., Li, Y., Liu, M., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.714338 · Cited by 7

Single-Cell Image-Based Analysis Reveals Chromatin Changes during the Acquisition of Tamoxifen Drug Resistance

Zhao, H., Lin, L. F., Hahn, J., Xie, J., Holman, H. F., & Yuan, C. (2022) · Life · doi:10.3390/life12030438 · Cited by 6

Mapping the cell-membrane proteome of the SKBR3/HER2+ cell line to the cancer hallmarks

Lazar, I. M., Karcini, A., & Haueis, J. R. S. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272384 · Cited by 7

An Integrated Dual‐Functional Nanotool Capable of Studying Single‐Cell Epigenetics and Programmable Gene Regulation

Shi, X., Xu, Y., Wang, B., Li, Z., Yu, S., Dong, H., Zhao, W., Jiang, D., Chen, H., & Xu, J. (2023) · Angewandte Chemie · doi:10.1002/ange.202302930 · Cited by 7

Proteomic approaches for cancer epigenetics research

Marchione, D. M., Garcia, B. A., & Wojcik, J. B. (2018) · Expert Review of Proteomics · doi:10.1080/14789450.2019.1550363 · Cited by 7

Nano-Biosensors for Cancer Diagnostics: Current Status and Future Prospects

Karki, K., Bisht, R., Shahi, K. S., Ranga, R., & Malik, U. (2019) · Journal of Nanoscience and Technology · doi:10.30799/jnst.260.19050415 · Cited by 7

Epigenetics and oral disease

Fox, S. A., Tiwari, L., & Farah, C. S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813762-8.00007-4 · Cited by 7

Identification of novel EED-EZH2 PPI inhibitors using an in silico fragment mapping method

Misawa, K., Yamaotsu, N., & Hirono, S. (2021) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-021-00378-6 · Cited by 7

Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers

Tran, M. T. M. T., Yeh, K., Chuang, Y., Hsu, P., Low, J.-T., Kumari, H., Lee, Y.-T., Chen, Y.-C., Huang, W.-H., Jin, H., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0250499 · Cited by 7

Expression of 5‐methylcytosine regulators is highly associated with the clinical phenotypes of prostate cancer and DNMTs expression predicts biochemical recurrence

Wang, L., Ren, G., & Lin, B. (2021) · Cancer Medicine · doi:10.1002/cam4.4108 · Cited by 7

Hypermethylation of DLG3 Promoter Upregulates RAC1 and Activates the PI3K/AKT Signaling Pathway to Promote Breast Cancer Progression

Liu, B., Xu, Y., Zhang, L., Yang, X. F., Chen, L., & Liu, Y. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/8428130 · Cited by 7

Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes

Lercher, L., Simon, N., Bergmann, A., Tauchert, M. J., Bochmann, D., Bashir, T., Neuefeind, T., Riley, D., Danna, B., Krawczuk, P. J., et al. (2022) · SLAS DISCOVERY · doi:10.1016/j.slasd.2022.04.003 · Cited by 7

JUN activation modulates chromatin accessibility to drive TNFα ‐induced mesenchymal transition in glioblastoma

Lv, X., Li, Q., Liu, H., Gong, M., Zhao, Y., Hu, J., Wu, F., & Wu, X. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17490 · Cited by 7

Epigenetic dynamics in normal and malignant B cells: die a hero or live to become a villain

Andrews, J. M., & Payton, J. E. (2018) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.09.020 · Cited by 7

Resistance is not the end: lessons from pest management

Whelan, C. J., & Cunningham, J. J. (2020) · Cancer Control · doi:10.1177/1073274820922543 · Cited by 7

Hierarchical assembly of the MLL1 core complex within a biomolecular condensate regulates H3K4 methylationPreprint

Namitz, K. E. W., Tan, S., & Cosgrove, M. S. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/870667 · Cited by 7

4sUDRB-sequencing for genome-wide transcription bursting quantification in breast cancer cellsPreprint

Beckman, W. F., Jiménez, M. Á. L., Moerland, P. D., Westerhoff, H. V., & Verschure, P. J. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.23.424175 · Cited by 6

Basic Epigenetic Mechanisms of Aging

Strazhesko, I. D., Yesakova, A. P., Akopyan, A. A., & Ткачева, О. Н. (2023) · Problems of Geroscience · doi:10.37586/2949-4745-2-2023-88-93 · Cited by 6

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

Furlano, K., Keshavarzian, T., Biernath, N., Fendler, A., Santis, M. D., Weischenfeldt, J., & Lupien, M. (2025) · International Journal of Cancer · doi:10.1002/ijc.35327 · Cited by 6

Comprehensive multimodal and multiomic profiling reveals epigenetic and transcriptional reprogramming in lung tumors

Wu, P., Liu, Z., Zheng, L., Du, Y., Zhou, Z., Wang, W., & Lu, C. (2025) · Communications Biology · doi:10.1038/s42003-025-07954-8 · Cited by 6

Tensor-FLAMINGO unravels the complexity of single-cell spatial architectures of genomes at high-resolution

Wang, H., Yang, J., Yu, X., Zhang, Y., Qian, J., & Wang, J. (2025) · Nature Communications · doi:10.1038/s41467-025-58674-w · Cited by 7

Role of stem cells in ageing and age-related diseases

Chaudhary, J. K., Danga, A. K., Kumari, A., Bhardwaj, A., & Rath, P. C. (2025) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2025.112069 · Cited by 6

NSD proteins in anti-tumor immunity and their therapeutic targeting by protein degraders

Chava, S., & Wajapeyee, N. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05806-6 · Cited by 6

USP8 deubiquitylation-boosted NSUN4 potentiates lung squamous cell carcinoma progression by m5C methylation of DHCR24

Jiang, Y., Zhu, P., Liu, Z., & Zhou, Y. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116158 · Cited by 6

Bridging-Induced Phase Separation and Loop Extrusion Drive Noise in Chromatin Transcription

Chiang, M., Battaglia, C., Forte, G., Brackley, C. A., Gilbert, N., & Marenduzzo, D. (2025) · Physical Review Letters · doi:10.1103/bjq4-xnsy · Cited by 9

Proteomic profiling of UV damage repair patches uncovers histone chaperones with central functions in chromatin repair

Plessier, A., Chansard, A., Petit, E., Ducassou, J. N., Couté, Y., & Polo, S. E. (2026) · Nature Communications · doi:10.1038/s41467-026-68781-x · Cited by 6

Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues

Kourtis, S., Zapater, A. G., Elbæk, C. R., Schmidt, A., Ghose, R., Coll‐Manzano, A., Espinar, L., Guirola, M., Lorente, N. P., García‐Cao, M., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-69217-2 · Cited by 6

Prostate Cancer Epigenetic Plasticity and Enhancer Heterogeneity: Molecular Causes, Consequences and Clinical Implications

Kneppers, J., Bergman, A. M., & Zwart, W. T. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-11836-4_15 · Cited by 6

Promoter hypermethylation of SFRP1 as a prognostic and potentially predictive blood-based biomarker in patients with stage III or IV pancreatic ductal adenocarcinoma

Stubbe, B. E., Madsen, P. H., Larsen, A. C., Krarup, H. B., Pedersen, I. S., Hansen, C. P., Johansen, J. S., Henriksen, S. D., & Thorlacius‐Ussing, O. (2023) · Pancreatology · doi:10.1016/j.pan.2023.05.003 · Cited by 6

The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer

Wang, A., Zheng, W.-S., Luo, Z., Bai, L., & Zhang, S. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-04995-1 · Cited by 6

Deciphering the Epigenetic Symphony of Cancer: Insights and Epigenetic Therapies Implications

Akram, F., Tanveer, R., Andleeb, S., Shah, F. I., Ahmad, T., Shehzadi, S., Akhtar, A. M., & Syed, G. (2024) · Technology in Cancer Research & Treatment · doi:10.1177/15330338241250317 · Cited by 6

Isocitrate Dehydrogenase Inhibitors in Glioma: From Bench to Bedside

Ser, M. H., Webb, M., Thomsen, A., & Sener, U. T. (2024) · Pharmaceuticals · doi:10.3390/ph17060682 · Cited by 6

Hepatitis B virus in Egypt: the whole story

Abdelhamed, W., & El‐Kassas, M. (2024) · Egyptian Liver Journal · doi:10.1186/s43066-024-00362-3 · Cited by 6

On Epigenetic Plasticity and Genome Topology

Lazaris, C., Aifantis, I., & Tsirigos, A. (2020) · Trends in cancer · doi:10.1016/j.trecan.2020.01.006 · Cited by 6

Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR

Puts, G. S., Jarrett, S. G., Leonard, M. K., Matsangos, N., Snyder, D. E., Wang, Y., Vincent, R., Portney, B. A., Abbotts, R., McLaughlin, L. J., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165896 · Cited by 6

Genomic Aberrations in Circulating Tumor DNAs from Palbociclib-Treated Metastatic Breast Cancer Patients Reveal a Novel Resistance Mechanism

Abu-Khalaf, M. M., Wang, C., Zhang, Z., Luo, R., Chong, W., Silver, D. P., Fellin, F., Jaslow, R. J., López, A., Cescon, T. P., et al. (2022) · Cancers · doi:10.3390/cancers14122872 · Cited by 6

Implications of Chromatin Modifier Mutations in Epigenetic Regulation of Bladder Cancer

Akman, B., & Erkek, S. (2022) · Exon Publications eBooks · doi:10.36255/exon-publications-urologic-cancers-bladder-cancer-epigenetics · Cited by 6

DNA barcoding and gene expression recording reveal the presence of cancer cells with unique properties during tumor progression

Umeki, Y., Ogawa, N., Uegaki, Y., Saga, K., Kaneda, Y., & Nimura, K. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04640-4 · Cited by 7

The first embryo, the origin of cancer and animal phylogeny. I. A presentation of the neoplastic process and its connection with cell fusion and germline formation

Cofré, J., & Saalfeld, K. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1067248 · Cited by 8

BRAF RNA is prognostic and widely expressed in lung adenocarcinoma

Dóra, D., Vörös, I., Varga, Z. V., Takacs, P., Téglási, V., Moldvay, J., & Lohinai, Z. (2023) · Translational Lung Cancer Research · doi:10.21037/tlcr-22-449 · Cited by 6

Downregulation of CLDN6 inhibits cell migration and invasion and promotes apoptosis by regulation of the JAK2/STAT3 signaling pathway in hepatocellular carcinoma

He, Z., Fan, F., Xu, Z., Zhang, M., Zhao, R., Ke, X., Wang, Q., Shanjun, Y., & Zheng, H. (2023) · Translational Cancer Research · doi:10.21037/tcr-23-19 · Cited by 6

BCL7B, a SWI/SNF complex subunit, orchestrates cancer immunity and stemness

Higuchi, S., Suehiro, Y., Izuhara, L., Yoshina, S., Hirasawa, A., & Mitani, S. (2023) · BMC Cancer · doi:10.1186/s12885-023-11321-3 · Cited by 6

Low-dose radiation from CT examination induces DNA double-strand breaks and detectable changes of DNA methylation in peripheral blood cells

Wang, S., Li, G., Du, H., & Feng, J. (2023) · International Journal of Radiation Biology · doi:10.1080/09553002.2023.2267667 · Cited by 6

Bile as a liquid biopsy matrix: potential applications and limitations

Arechederra, M., Rullán, M., Oyón, D., Avila, M. A., Urmán, J., & Berasain, C. (2024) · Exploration of Digestive Diseases · doi:10.37349/edd.2024.00037 · Cited by 6

Rapid signaling reactivation after targeted BRAF inhibition predicts the proliferation of individual melanoma cells from an isogenic population

Khoshkenar, P., Lowry, E., & Mitchell, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-94941-8 · Cited by 6

Development and validation of a novel epigenetic-related prognostic signature and candidate drugs for patients with lung adenocarcinoma

Wang, Z., Embaye, K. S., Yang, Q., Qin, L., Zhang, C., Liu, L., Zhan, X., Zhang, F., Wang, X., & Qin, S. (2021) · Aging · doi:10.18632/aging.203315 · Cited by 6

Targeting Cancer at the Intersection of Signaling and Epigenetics

Guerra, S. L., & Cichowski, K. M. (2018) · Annual Review of Cancer Biology · doi:10.1146/annurev-cancerbio-030617-050400 · Cited by 7

Visualizing Human Colorectal Cancer Intratumor Heterogeneity with Phylogeography

Shibata, D. K. (2020) · iScience · doi:10.1016/j.isci.2020.101304 · Cited by 6

A neural crest stem cell-like state drives nongenetic resistance to targeted therapy in melanomaPreprint

Marín-Béjar, O., Rogiers, A., Dewaele, M., Femel, J., Karras, P., Poźniak, J., Bervoets, G., Raemdonck, N. V., Pedri, D., Swings, T., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.15.422929 · Cited by 6

Transgenerational transcriptional heterogeneity from cytoplasmic chromatinPreprint

Papathanasiou, S., Mynhier, N. A., Liu, S., Jacob, E., Stokasimov, E., van Steensel, B., Zhang, C., & Pellman, D. S. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.12.475869 · Cited by 6

Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programsPreprint

Saintilnord, W. N., Hegazy, Y. A., Chesnutt, K. V., Eckstein, M., Cassidy, R. N., Dhahri, H., Bennett, R. L., Melters, D. P., Lopes, É. N., Fu, Z., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.18.624207 · Cited by 6

Quantifying cell fate change under different stochastic gene activation frameworks

Chen, X., Sheng, Y., Chen, L., Tang, M., & Jiao, F. (2024) · Quantitative Biology · doi:10.1002/qub2.82 · Cited by 5

Epigenetic deprogramming by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers

Turvey, G. L., de Alba, E. L., Stewart, E., Cook, H., Alalti, A., Gawne, R. T., Ainscough, J., Mason, A. S., & Coverley, D. (2025) · The Journal of Cell Biology · doi:10.1083/jcb.202409123 · Cited by 5

Debates and progress in the management of intermediate-stage (BCLC stage B) hepatocellular carcinoma

Jiang, J., Cao, Y., Gao, S., Hu, Y., Yang, S., & Tang, H. (2025) · iLiver · doi:10.1016/j.iliver.2025.100187 · Cited by 5

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Lapin, M., Tjensvoll, K., Edland, K. H., Oltedal, S., Garresori, H., Gilje, B., Ekedal, S., Eftestøl, T. C., Kvaløy, J. T., Janku, F., et al. (2025) · Molecular Oncology · doi:10.1002/1878-0261.70116 · Cited by 8

Intercellular signaling reinforces single-cell level phenotypic transitions and facilitates robust re-equilibrium of heterogeneous cancer cell populations

Lopez, D. E. R., Tyson, D. R., & Hong, T. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02405-7 · Cited by 5

A narrative review of therapy-induced senescence in cancer: mechanisms, immune interplay, and therapeutic opportunities

Sutanto, H., Ahkami, A., Fetarayani, D., & Romadhon, P. Z. (2025) · Journal of the Egyptian National Cancer Institute · doi:10.1186/s43046-025-00333-8 · Cited by 7

Tucidinostat Plus R-CHOP vs R-CHOP in MYC/BCL2 Double-Expressor Diffuse Large B-Cell Lymphoma

Xu, P.-P., Song, Y.-Q., Shen, J.-Z., Cai, Q.-Q., Zhou, H., Zhang, L., Xiang, Y., Sun, X., Yang, W., Yao, Z.-H., et al. (2026) · JAMA · doi:10.1001/jama.2026.4199 · Cited by 5

Geographically weighted linear combination test for gene-set analysis of a continuous spatial phenotype as applied to intratumor heterogeneity

Amini, P., Hajihosseini, M., Pyne, S., & Dinu, I. A. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1065586 · Cited by 5

Strategies to enhance the response of liver cancer to pharmacological treatments

Marín, J. J. G., Macías, R. I. R., Asensio, M., Romero, M. R., Temprano, Á. G., Pereira, O. R., Jimenez, S., Mauriz, J. L., Giacomo, S. D., Avila, M. A., et al. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00176.2024 · Cited by 7

Targeting CREB-binding protein (CBP) abrogates colorectal cancer stemness through epigenetic regulation of C-MYC

Chung, D.-J., Wang, C., Liu, P.-J., Ng, S.-K., Luo, C.-K., Jwo, S.-H., Li, C.-T., Hsu, D.-Y., Fan, C.-C., & Wei, T.-T. (2024) · Cancer Gene Therapy · doi:10.1038/s41417-024-00838-9 · Cited by 5

Evidence of Epigenetic Oncogenesis: A Turning Point in Cancer Research

Capp, J., Aliaga, B., & Pancaldi, V. (2024) · BioEssays · doi:10.1002/bies.202400183 · Cited by 7

Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma

Griess, O., Furth, N., Harpaz, N., Bernardo, N. D., Salame, T., Dassa, B., Karagiannidis, I., Isshiki, Y., Gross, M., Melnick, A. M., et al. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003191 · Cited by 6

Optimal dosing of anti-cancer treatment under drug-induced plasticity

Gunnarsson, E. B., Magnússon, B. V., & Foo, J. (2025) · npj Systems Biology and Applications · doi:10.1038/s41540-025-00571-5 · Cited by 6

Paradoxes of tumour complexity: somatic selection, vulnerability by design, or infectious aetiology?

Apari, P., & Müller, V. (2018) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12490 · Cited by 5

Deubiquitinating enzyme inhibitor alleviates cyclin A1‐mediated proteasome inhibitor tolerance in mixed‐lineage leukemia

Ge, M., Xu, Q., Kang, T., Li, D., Wang, R., Chen, Z., Xie, S., Wang, W., & Liu, H. (2021) · Cancer Science · doi:10.1111/cas.14892 · Cited by 5

Clinical significance of tumor suppressor genes methylation in circulating tumor DNA of patients with pancreatic cancer

Xin, W., Tu, S., Yi, S., Xiong, Y., Fang, K., Sun, G., & Xiao, W. (2023) · Gene · doi:10.1016/j.gene.2023.148078 · Cited by 5

Épigénétique et cancer

Gorse, M., Bianchi, C., & Proudhon, C. (2024) · médecine/sciences · doi:10.1051/medsci/2024180 · Cited by 5

KLF4 Promotes a KRT13+ Hillock-Like State in Lung Squamous Cell Carcinoma

Izzo, L., Reyes, T., Meesala, S., Ireland, A. S., Earnest-Noble, L. B., Yang, S. S., Sunil, H. S., Cheng, X. C., Tserentsoodol, N., Hawgood, S. B., et al. (2026) · Cancer Research · doi:10.1158/0008-5472.can-26-0531 · Cited by 5

In silico clinical trials for anti-aging therapies

Menéndez, J. A., Cuyàs, E., Folguera-Blasco, N., Verdura, S., Martín-Castillo, B., Joven, J., & Alarcón, T. (2019) · Aging · doi:10.18632/aging.102180 · Cited by 5

Weighted Gene Coexpression Network Analysis Reveals the Dynamic Transcriptome Regulation and Prognostic Biomarkers of Hepatocellular Carcinoma

Qu, S., Shi, Q., Xu, J., Yi, W., & Fan, H. (2020) · Evolutionary Bioinformatics · doi:10.1177/1176934320920562 · Cited by 5

Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells

Zhou, J. H. S., Guo, C., Wu, H., Li, B., Zhou, L., Liang, A., & Fu, J. (2021) · BMC Cancer · doi:10.1186/s12885-021-08915-0 · Cited by 6

Spatial Multiomics Analysis Reveals Only Minor Genetic and Epigenetic Changes in Human Liver Cancer Stem-Like Cells Compared With Other Tumor Parenchymal Cells

Liu, D., Li, H., Dong, H. F., Qu, M., Yang, L., Chen, L., Li, Y., Wang, H., & He, Y. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.810687 · Cited by 5

Dissecting cell fate dynamics in pediatric glioblastoma through the lens of complex systems and cellular cybernetics

Uthamacumaran, A. (2022) · Biological Cybernetics · doi:10.1007/s00422-022-00935-8 · Cited by 5

Does memantine show chemopreventive effect against mice 4T1 breast tumor model?

Albayrak, G., Bali, E. B., Korkmaz, F. D., & Bağrıaçık, E. Ü. (2022) · TURKISH JOURNAL OF MEDICAL SCIENCES · doi:10.55730/1300-0144.5381 · Cited by 5

Computational methods to explore chromatin state dynamics

Orouji, E., & Raman, A. T. (2022) · Briefings in Bioinformatics · doi:10.1093/bib/bbac439 · Cited by 5

Dissecting the Origin of Heterogeneity in Uterine and Ovarian Carcinosarcomas

Sertier, A.-S., Ferrari, A., Pommier, R. M., Treilleux, I., Boyault, S., Devouassoux‐Shisheboran, M., Kielbassa, J., Thomas, E., Tonon, L., Texier, V. L., et al. (2023) · Cancer Research Communications · doi:10.1158/2767-9764.crc-22-0520 · Cited by 5

TriPCE: A Novel Tri-Clustering Algorithm for Identifying Pan-Cancer Epigenetic Patterns

Gan, Y., Li, N., Xin, Y., & Zou, G. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2019.01298 · Cited by 5

Epigenetic changes induced by Bacteroides fragilis toxin (BFT)Preprint

Allen, J., Hao, S., Sears, C. L., & Timp, W. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/301374 · Cited by 5

A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation

Ge, A. Y., Arab, A., Dai, R., Navickas, A., Fish, L., Garcia, K., Asgharian, H., Goudreau, J., Lee, S., Keenan, K., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-77314-9 · Cited by 4

Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco

Mishra, A. K., Mumtaz, N., & Misra, M. K. (2023) · Frontiers in Bioscience-Scholar · doi:10.31083/j.fbs1504013 · Cited by 4

TP63 mediates the generation of tumour-specific chromatin loops that underlie MYC activation in radiation-induced tumorigenesis

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Chromatin remodeling restrains oncogenic functions in prostate cancer

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Multi-omics analysis reveals the crosstalk of epigenetic regulatory networks in cutaneous squamous cell carcinoma progression

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Condensates and cell states: A new paradigm for understanding tumor biology

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Cancer in 4D: toward Spatiotemporal Hallmark Ecosystems

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Pre-Adaptive States and Evolutionary Trajectories in Breast Cancer Drug Resistance: From Drug-Tolerant Persisters to Clonal Evolution

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Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia

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CRISPR perfect adaptation for robust control of cellular immune and apoptotic responses

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Cause and effect in epigenetics – where lies the truth, and how can experiments reveal it?

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Camptothecin Encapsulated in β-Cyclodextrin-EDTA-Fe3O4 Nanoparticles Induce Metabolic Reprogramming Repair in HT29 Cancer Cells through Epigenetic Modulation: A Bioinformatics Approach

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The connection between innervation and metabolic rearrangements in pancreatic cancer through serine

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Phenotypic and transcriptomic impact of expressing mammalian TET2 in theDrosophila melanogastermodel

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BRD4-binding enhancer promotes CRC progression by interacting with YY1 to activate the Wnt pathway through upregulation of TCF7L2

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Seven chromatin regulators as immune cell infiltration characteristics, potential diagnostic biomarkers and drugs prediction in hepatocellular carcinoma

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Genome-wide analysis of circulating tumor DNA methylation profiles in cerebrospinal fluid: a clinical trial of oncolytic virus for glioblastoma.

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Epigenetic memory is governed by an effector recruitment specificity toggle in Heterochromatin Protein 1

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Cancer epigenetics in the driver's seat

Kiberstis, P. A. (2017) · Science · doi:10.1126/science.357.6348.263-i · Cited by 1

Epigenetic plasticity, selection, and tumorigenesis

Flavahan, W. A. (2020) · Biochemical Society Transactions · doi:10.1042/bst20191215 · Cited by 31

The Effects of Chromatin and Epigenetics on Cancer and Tumorigenesis

Fischer, P. (2019) · Microreviews in Cell and Molecular Biology

Epigenetics as a mediator of plasticity in cancer

Feinberg, A. P., & Levchenko, A. (2023) · Science · doi:10.1126/science.aaw3835 · Cited by 267

Epigenetic regulation of the cell cycle & DNA-repair in cancer

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