Organoids-on-a-chip

Cerebral organoids model human brain development and microcephaly

Lancaster, M. A., Renner, M., Martin, C.-A., Wenzel, D., Bicknell, L. S., Hurles, M. E., Homfray, T., Penninger, J. M., Jackson, A. P., & Knoblich, J. A. (2013) · Nature · doi:10.1038/nature12517 · Cited by 5,372

Reconstituting organ-level lung functions on a chip

Huh, D., Matthews, B. D., Mammoto, A., Montoya-Zavala, M., Hsin, H. Y., & Ingber, D. E. (2010) · Science · doi:10.1126/science.1188302 · Cited by 4,250

Microfluidic organs-on-chips

Bhatia, S. N., & Ingber, D. E. (2014) · Nature Biotechnology · doi:10.1038/nbt.2989 · Cited by 3,305

Modeling Development and Disease with Organoids

Clevers, H. (2016) · Cell · doi:10.1016/j.cell.2016.05.082 · Cited by 3,196

Organogenesis in a dish: Modeling development and disease using organoid technologies

Lancaster, M. A., & Knoblich, J. A. (2014) · Science · doi:10.1126/science.1247125 · Cited by 2,931

Soft Lithography in Biology and Biochemistry

Whitesides, G. M., Ostuni, E., Takayama, S., Jiang, X., & Ingber, D. E. (2001) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.3.1.335 · Cited by 2,603

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

Qian, X., Nguyen, H. N., Song, M. M., Hadiono, C., Ogden, S. C., Hammack, C., Yao, B., Hamersky, G. R., Jacob, F., Zhong, C., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.032 · Cited by 2,127

From 3D cell culture to organs-on-chips

Huh, D., Hamilton, G. A., & Ingber, D. E. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.09.005 · Cited by 1,834

Mechanical forces direct stem cell behaviour in development and regeneration

Vining, K. H., & Mooney, D. J. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.108 · Cited by 1,656

Three-dimensional bioprinting of thick vascularized tissues

Kolesky, D. B., Homan, K. A., Skylar-Scott, M. A., & Lewis, J. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1521342113 · Cited by 1,492

Perfusion Window Chambers Enable Interventional Analyses of Tumor Microenvironments

Korolj, A., Köhler, R. H., Scott, E., Halabi, E. A., Lucas, K., Carlson, J., & Weissleder, R. (2023) · Advanced Science · doi:10.1002/advs.202304886 · Cited by 4

A Political and ethical landscape of brain organoid research

Schneider, E., Samsa, L. A., & Dubljević, V. (2024) · Molecular Psychology Brain Behavior and Society · doi:10.12688/molpsychol.17521.2 · Cited by 5

Human Pluripotent Stem Cell-derived Hepatic Organoids: A Promising Novel Model of Liver Diseases

Jin, B., Wu, X., & Du, S. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.09.062 · Cited by 5

Role of exchange proteins directly activated by cAMP signaling in vascular remodeling

Cheng, X., Liu, H., Zhang, W., Yang, W., & Mei, F. C. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100078 · Cited by 4

Engineering brain organoids and organ-on-chip systems for modeling neurodevelopmental and neurodegenerative pathophysiology

Banerjee, S., Chandu, P. M., Sarkar, M., Soni, T. K., Saha, M., Fathah Muhammad, L., Chatterjee, B., & Das, U. (2025) · Neurological Research · doi:10.1080/01616412.2025.2600434 · Cited by 5

Bone-on-a-chip technology review: Clinical applications, scientific advancements, and challenges

Nejati, O., Madani, G., Mazhari, Z., Dayhimi, V., Gharivi, M., Babaeizad, A., Mofazali, P., & Farshid, S. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107565 · Cited by 4

Construction, evaluation, and applications of renal barrier-on-a-chip system

Naren, T., Lv, W., Aazmi, A., Wang, Y., Yu, H., Lee, J. Y., Yang, H., Yu, M., Jiang, X., Yang, H., et al. (2026) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.12.032 · Cited by 4

ROS‐Responsive Hybrid Nanoparticles Enable Dual‐Target Neurovascular Repair via Blood–Brain Barrier‐on‐Chip Validation

Cai, S., Bi, W., Li, L., Gao, X., Sun, C., Hang, Z., Chen, H., Li, Y. F., Xing, C., Wang, L., et al. (2026) · Small · doi:10.1002/smll.202507595 · Cited by 4

Human Organoids and Organ-on-Chip for Biotoxin Assessment: Applications, Best Practices, and a Translational Roadmap

Li, M., Huang, S., Jia, J., Feng, Y., & Zhang, J. (2026) · Toxins · doi:10.3390/toxins18030149 · Cited by 4

Organ Chips and Visualization of Biological Systems

Tian, T., Liu, J., & Zhu, H. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-32-9902-3_8 · Cited by 4

Investigating retinal explant models cultured in static and perfused systems to test the performance of exosomes secreted from retinal organoids

Yang, T., Wang, W., Xie, L., Chen, S., Ye, X., Shen, S., Chen, H., Qi, L., Cui, Z., Xiong, W., et al. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110181 · Cited by 4

Ginsenoside Rb1 improves human nonalcoholic fatty liver disease with liver organoids-on-a-chip

Wang, H., Zhu, Y., Shi, P., Li, X., Bu, Q., Li, Y., You, X., & Zhao, G. (2024) · Engineered Regeneration · doi:10.1016/j.engreg.2024.06.002 · Cited by 4

Applications and perspectives of tumor organoids in radiobiology (Review)

Jin, Y., Wang, K., Tang, Y., & Zheng, D. (2024) · Oncology Reports · doi:10.3892/or.2024.8759 · Cited by 5

Animal models for transplant immunology: bridging bench to bedside

Kang, M., Park, H. K., Kim, K. S., & Choi, D. (2024) · Clinical Transplantation and Research · doi:10.4285/ctr.24.0029 · Cited by 4

Optical coherence tomography and its recent applications for three-dimensional imaging of organoids

Choi, W. J., & Choi, E. S. (2024) · Organoid · doi:10.51335/organoid.2024.4.e7 · Cited by 5

Emerging supramolecular and living materials in oral medicine

Fischer, N. G., Lin, T.-Y., Xiang, Y., Sang, T., & Ye, Z. (2025) · Trends in biotechnology · doi:10.1016/j.tibtech.2025.03.006 · Cited by 4

Rigid and soft microelectrodes for electrophysiology measurement

Gong, H., Weng, W., Zhang, S., Gao, Z., & Hu, N. (2025) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2025.100591 · Cited by 4

The Role of HER2 in Cancer and Its Influence on the Tumor Microenvironment

Choi, S., Kim, M., & Kim, M. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1009458 · Cited by 4

Targeting tumor resistance mechanisms

Gerard, L., Duvivier, L., & Gillet, J. (2021) · Faculty Reviews · doi:10.12703/r/10-6 · Cited by 4

An Integrated Pulsation-Free, Backflow-Free Micropump Using the Analog Waveform-Driven Braille Actuator

Nishikata, K., Nakamura, M., Arai, Y., & Futai, N. (2022) · Micromachines · doi:10.3390/mi13020294 · Cited by 4

Selenium Supplementation Sensor Based on Direct Electrochemistry of Urinary Selenosugar and Total Selenium

Song, M., Chen, J., Si, J., Man, T., Yao, Q., Zhu, F., Lv, F., Piao, Y., Wan, Y., Zhu, C., et al. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c02391 · Cited by 4

Optimizing skin pharmacotherapy for older patients: the future is at hand but are we ready for it?

Hausmann, C., Vogt, A., Kerscher, M. J., Ghoreschi, K., Schäfer‐Korting, M., & Zoschke, C. (2020) · Drug Discovery Today · doi:10.1016/j.drudis.2020.01.011 · Cited by 4

Fabrication of Ultra-Thin Micro-Porous PDMS Membrane for Cell Co-Culture in Blood Brain Barrier Model on Chip

Zheng, F., Li, Q., Yang, P., Qiu, S., Mao, H., & Zhao, J. (2021) · International Conference on Solid-State Sensors, Actuators and Microsystems · doi:10.1109/transducers50396.2021.9495546 · Cited by 4

Human Vascularized Bile Duct-on-a Chip: A multi-cellular micro-physiological system for studying Primary Sclerosing CholangitisPreprint

Du, Y. M., Gupta, K., Waisbourd‐Zinman, O., Har‐Zahav, A., Soroka, C. J., Boyer, J. L., Llewellyn, J., Liu, C., Naji, A., Polacheck, W. J., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.02.530888 · Cited by 4

A Co-culture of Staphylococcus epidermidis and Staphylococcus aureus in a Monodisperse Droplet to Investigate Microbial Interaction at Defined Microenvironment

Jung, S.-Y., Kim, K. H., Kim, J. S., Hwang, B.-H., & Lee, C. (2025) · Korean Journal of Chemical Engineering · doi:10.1007/s11814-025-00476-3 · Cited by 4

Tumor-adipose assembloids reveal cell-fate-transition-triggered multistage collective invasions

Lei, M., Li, J., Ren, X., Xie, H., Li, P., Qi, F., Shi, J., Cai, X., Liu, Y., Chen, P., et al. (2025) · Cell Systems · doi:10.1016/j.cels.2025.101353 · Cited by 3

Phenotype–Target Coupled Drug Screening: A High-Efficiency Framework for Innovative Drug Discovery from CHMs

Zhou, W. J., & Gao, Y. (2025) · Engineering · doi:10.1016/j.eng.2025.11.019 · Cited by 3

A workflow integrating organ-on-chip culture and correlative 3D light and electron microscopy for microtissue analysis

Schaart, J. M., Wasserberg, D., Cruz, M. A. E., Lindert, M. K., van der Meijden, R. H. M., Roverts, R., Debera, N., Lu, M. P., Rouwkema, J., Nijhuis, W. H., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-27587-5 · Cited by 3

Advanced technologies of artery-on-a-chip: a review of construction strategies and disease models

Chang, S.-Q., Qiao, L., Abodunrin, O. D., Zou, L., & Huang, N. (2026) · Angiogenesis · doi:10.1007/s10456-026-10030-2 · Cited by 4

Harnessing PDX and PDX 2.0: the next-generation paradigm for precision oncology and translational breakthroughs

Jian, C., Fu, H., Wu, W., Zhang, N., Liu, Z., Xia, Z., Luo, P., Zhang, H., & Cheng, Q. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02594-w · Cited by 4

Fabrication of Tissue Constructs and Organoids Using Electrospun Micro/Nanofibers

Wu, T. S., Hao, R., Su, Q., Sun, L., Zhang, T., Du, J., Fu, M., Wang, Y., Xue, J., & Li, X. (2026) · Chemical Reviews · doi:10.1021/acs.chemrev.5c01140 · Cited by 4

Deconstructing cancer in 3D: models, mechanisms, and personalized solutions

Huang, Z., Duan, X., Ji, J., Cai, Q., Jin, P., Yu, B., & (48506), J. Z. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02704-8 · Cited by 5

Tumor organoid-immune cell co-culture systems for precision oncology

Cai, L., Xiao, Y., Xie, F., & Yang, Z. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1865487 · Cited by 3

Organoids Models for the Study of Cell-Cell Interactions

Jiménez-Palomares, M., Cristobal, A., & Durán-Ruiz, M. C. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.94562 · Cited by 3

Advanced human liver models for the assessment of drug-induced liver injury

Mun, S. J., Lee, J., Shin, Y., & Son, M. J. (2022) · Organoid · doi:10.51335/organoid.2022.2.e17 · Cited by 4

Application of biomechanics in tumor epigenetic research

Wang, Q., Yin, X., Ding, Y., Zhao, H., & Luo, Y. (2024) · Mechanobiology in Medicine · doi:10.1016/j.mbm.2024.100093 · Cited by 4

Organs-on-chips: Advanced engineered living systems

Liu, Y., & Bian, L. (2024) · APL Bioengineering · doi:10.1063/5.0250720 · Cited by 3

Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models

Fu, Y., Fan, Q., Wu, Y., & Bao, M. (2025) · Trends in biotechnology · doi:10.1016/j.tibtech.2025.02.015 · Cited by 3

Biomimetic gender-specific human skin model based on gonads/epidermis-on-a-chip

Wu, X., Zhang, Y., Xu, Y., Cao, X., & Zhao, Y. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.07.014 · Cited by 3

Brain organoids for addressing COVID-19 challenge

Yu, J. S., Wang, K., & Zheng, D. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1055601 · Cited by 3

Progress of 3D Organoid Technology for Preclinical Investigations: Towards Human In Vitro Models

Liu, Y., Xu, H., Abraham, S., Wang, X., & Keavney, B. D. (2022) · International Journal of Drug Discovery and Pharmacology · doi:10.53941/ijddp.v1i1.188 · Cited by 4

Mammalian Cell Culture in Three Dimensions: Basic Guidelines

Malik, P., & Mukherjee, T. K. (2023) · Springer eBooks · doi:10.1007/978-981-19-1731-8_13-1 · Cited by 3

Advancements in life-on-a-chip: The impact of “Beyond Limits Manufacturing” technology

He, W., Zhang, H., Lin, X., Zhu, L., Zheng, T., Pei, H., Tian, Y., Zhang, M., Shi, G., Wu, L., et al. (2023) · Chinese Chemical Letters · doi:10.1016/j.cclet.2023.109091 · Cited by 3

Imaging Techniques and Clinical Application of the Marrow–Blood Barrier in Hematological Malignancies

Zhang, J., Huang, Q., Bian, W., Wang, J., Guan, H., & Niu, J. (2023) · Diagnostics · doi:10.3390/diagnostics14010018 · Cited by 3

Advances and Applications of Lung Organoids in the Research on Acute Respiratory Distress Syndrome (ARDS)

Zhang, X., Su, L., & Pan, P. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13020346 · Cited by 3

Combating Cellular Aging: Frontiers in Biomaterials and Therapies

Liu, S., Mou, J., Zhao, C., Du, C., Liu, J., Bao, W., Xiao, H., Huang, W., Liao, J., & Lei, Y. (2024) · ACS Materials Letters · doi:10.1021/acsmaterialslett.4c02108 · Cited by 4

Opportunities for Investing in Organ-on-a-Chip (OoC) Technology, Breast-on-a-Chip (BoC) as an Example Technology Transfer into Islamic Development Bank Members Countries (IsDB-MCs)

Elnour, A. A. M., Ashammakhi, N. A., & Sallam, E. B. (2025) · Springer eBooks · doi:10.1007/978-981-97-8518-6_7 · Cited by 3

Organ-on-a-chip

Zhang, P. (2021) · Elsevier eBooks · doi:10.1016/b978-0-444-59432-7.00007-8 · Cited by 3

Developmental bioengineering: recapitulating development for repair

Goldfield, E. C., & Coppens, M. (2020) · Molecular Systems Design & Engineering · doi:10.1039/d0me00062k · Cited by 3

Editorial: Organ mimicking technologies and their applications in drug discovery

Zhang, X., Luo, Y., & Wang, Q. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1341153 · Cited by 3

Skin-on-a-Chip Coupled with a Rapid Inflammation Detection System for Cosmetic Ingredient Screening

Liu, Z., Wu, B., Tu, Y., Duan, T., Cheng, K., Lv, Z., Yin, R., Li, H., & Zhang, H. (2024) · Biomedical Materials & Devices · doi:10.1007/s44174-024-00204-1 · Cited by 2

Screening anti-inflammatory and neuroprotective effects of nanozyme with human cortical organoid-on-a-chip

Wu, G., Wang, H., & Chen, L. (2025) · APL Materials · doi:10.1063/5.0272502 · Cited by 2

Coiled-coil lipopeptides mediated membrane fusion based drug delivery into a mimicking lung organ

Wang, X., Wan, W., Liu, G., Ren, T., Thomas, J. O., Wu, H., An, C., Tian, F., Zhu, Y., Kros, A., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.163333 · Cited by 2

Cell‐embedded microgels as emerging miniature 3D tissue‐mimics toward biochip‐based toxicity screening

Delafosse, M., Regnault, E., Gebauer‐Barrett, J., Manz, A., & Sung, B. (2025) · Bioengineering & Translational Medicine · doi:10.1002/btm2.70061 · Cited by 2

Organoids as a Tool for Assessing Drinking Water Safety and Guidelines Relevance

Coppo, R., & Bertone, E. (2025) · Organoids · doi:10.3390/organoids4040031 · Cited by 2

Lab on an end: Micromanipulation using the acoustohydrodynamic pillar array as an end effector

Chen, Z., Bai, C., Liu, F., Huang, Q., Fukuda, T., Arai, T., & Liu, X. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2505479122 · Cited by 2

Microfluidic lung cancer models: Bridging clinical treatment strategies and tumor microenvironment recapitulation

Yu, Z., Khan, A. A., Naeem, W., Borgia, J. A., Liptay, M. J., Seder, C. W., & Zhou, J. (2025) · APL Bioengineering · doi:10.1063/5.0282002 · Cited by 2

The application of experimental models for the drug discovery for digestive tumors

Zheng, L., Shuai, W., Liu, Y., Deng, Y., Bao, J., Hu, X., & Wang, G. (2026) · Molecular Cancer · doi:10.1186/s12943-025-02558-6 · Cited by 2

Organoid Models of the Oral Mucosa for Precision Medicine

Atwa, A., Wadan, A. S., Hallool, S. I., Shati, A. A., Elbehairi, S. E. I., Alfaifi, M. Y., & Hussein, A. M. (2026) · Tissue Engineering Part B Reviews · doi:10.1177/19373368261420588 · Cited by 3

Organ-on-a-chip systems for osteochondral units: unveiling biomechanical and pathological mechanisms

Liu, Y., Li, J., Gao, F., Zhang, T., Wang, C. M., & Wang, W. (2026) · Biofabrication · doi:10.1088/1758-5090/ae4dbf · Cited by 2

Emerging organoids and organoids-on-chip platforms for translational development of antibody‒drug conjugates and next-generation bioconjugates

Hu, Z., Liao, Y., Niu, M., Kong, Z., Vankelecom, H. E. J., Cheng, J., Deleidi, M., Li, C., Jiang, Z., Bian, S., et al. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.05.032 · Cited by 2

Standard: human breast cancer organoids derived from diverse clinical sample sources

Chen, Z., Xu, N., Chen, M., Hu, J., Yu, Z., Zhu, S., Zhang, Y., Zhang, R., Wang, K., Wang, S., et al. (2026) · Cell Regeneration · doi:10.1186/s13619-026-00291-z · Cited by 2

Pregnancy-associated organs-on-chips

Pérez-Dávalos, L. A., McColman, S., Abdelkarim, M., Moon, B., Malic, L., Veres, T., Radisic, M., & Labouta, H. I. (2026) · Nature Reviews Bioengineering · doi:10.1038/s44222-026-00459-x · Cited by 2

Organoid technology in cancer research

Zhang, J., & He, J. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00505-5 · Cited by 3

Multicellular systems to translate somatic cell genome editors to human

Hernandez‐Gordillo, V., Casolaro, T. C., Ebrahimkhani, M. R., & Kiani, S. (2020) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2020.100249 · Cited by 2

Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device

Tung, Y., Wang, C., Huang, Y.-K., Huang, C.-K., Peng, C., Patra, B., Chen, H.-K., Tsao, P., & Ling, T. (2021) · Talanta · doi:10.1016/j.talanta.2021.122882 · Cited by 2

The application and research advances of organoids in clinical medicine

Mo, S., Guan, R., Long, Z., Cai, S., Peng, J., & GuoQiang, H. U. A. (2021) · Scientia Sinica Vitae · doi:10.1360/ssv-2021-0315 · Cited by 2

Nicotinamide Mononucleotide Alleviates Angiotensin II-Induced Human Aortic Smooth Muscle Cell Senescence in a Microphysiological Model

Yin, X., Abudupataer, M., Yang, M., Xiang, B., Lai, H., Wang, C., Li, J., & Zhu, K. (2023) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001400 · Cited by 2

A platform for modular assembly and feeding of micro-organoids on standard Petri dishes

Nebuloni, F., Morgan, J., Walsh, E. J., & Cook, P. R. (2023) · Biology Open · doi:10.1242/bio.059825 · Cited by 2

Growing organoids and spheroids on a chip

Nuairi, A. A., Sahloul, S., Orozaliev, A., Percipalle, P., & Song, Y. (2023) · IEEE International Conference on Nano/Micro Engineered and Molecular Systems · doi:10.1109/nems57332.2023.10190866 · Cited by 2

Application of hydrogel materials for organoids

Qin, X., Liu, H., Gan, Z., & Qin, J. (2023) · Scientia Sinica Chimica · doi:10.1360/ssc-2023-0129 · Cited by 2

Robot-Assisted Precise Manufacturing of Tissue Spheroid in Single-Cell Scale

Huang, G., Chen, Y., Jiang, M., & Tong, M. (2023) · Annual Conference of the IEEE Industrial Electronics Society (IECON) · doi:10.1109/iecon51785.2023.10312405 · Cited by 2

Three-Dimensional Cultivation a Valuable Tool for Modelling Canine Mammary Gland Tumour Behaviour In Vitro

Huniadi, M., Nosálová, N., Almášiová, V., Horňáková, Ľ., Valenčáková-Agyagosová, A., Hudáková, N., & Cizkova, D. (2024) · Cells · doi:10.3390/cells13080695 · Cited by 3

[Application and Research Progress of Lung Cancer Organoid in Precision Medicine for Lung Cancer].

Huang, Z., Li, B., Wang, Y., Xue, J., Wei, Z., Liang, N., & Li, S. (2024) · PubMed Central · doi:10.3779/j.issn.1009-3419.2024.106.07 · Cited by 2

Converging neural-centric and mechano-regulation in organoid modeling for system biology and medicine

Tang, J., Wang, Z., Khutsishvili, D., Zhu, Y., Li, J., Yu, F., Sang, G., Zeng, J., Yi, Z., Huang, Y.-C., et al. (2024) · The Innovation Medicine · doi:10.59717/j.xinn-med.2024.100076 · Cited by 3

Morphogenetic Designs, and Disease Models in Central Nervous System Organoids

Bock, M., Hong, S. J., Zhang, S., Yu, Y., Lee, S., Shin, H.-E., Choi, B. H., & Han, I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147750 · Cited by 3

Evaluating the nutritional value of functional molecules for food processing using tissue and organoid models

Wan, A. C. A. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104834 · Cited by 2

Advances in Organ-on-a-chip Technologies for Biomedical Research and Applications

Zhu, Q., Liao, M., Hu, Y., & Chai, R. (2025) · Materials Lab · doi:10.54227/mlab.20240006 · Cited by 2

Strategies for the vascularization and immune modeling of human tumor organoids based on advanced technologies

Li, R. M., Dong, Q., Jian, H., & Bai, S. (2025) · Precision medicine and engineering. · doi:10.1016/j.preme.2025.100030 · Cited by 5

Gynecological malignancy organoids: A game changer for personalized medicine

Ding, Z., Chang, X., Qu, X., Hua, K., & Qiu, J. (2025) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2025.189405 · Cited by 2

Applying the Cytocentric Principles to Regenerative Medicine for Reproducibility

Henn, A. D., Mitra, K., Hunsberger, J. G., Sun, X. S., Nardone, M., Montero, R. B., Somara, S., Green, G., Blanchard, A., Zhang, Y. S., et al. (2022) · Current Stem Cell Reports · doi:10.1007/s40778-022-00219-8 · Cited by 2

A Political and ethical landscape of brain organoid research

Schneider, E., Samsa, L. A., & Dubljević, V. (2023) · Molecular Psychology Brain Behavior and Society · doi:10.12688/molpsychol.17521.1 · Cited by 6

Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chipsPreprint

Spitz, S., Zanetti, C., Bolognin, S., Muwanigwa, M. N., Smits, L. M., Berger, E., Jordan, C., Harasek, M., Schwamborn, J. C., & Ertl, P. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/869701 · Cited by 2

Understanding immune-driven brain aging by human brain organoid microphysiological analysis platformPreprint

Song, S., Ao, Z., Cai, H., Li, X., Miao, Y., Wu, Z., Krzesniak, J., Gu, M., Lee, L. P., & Guo, F. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.19.476989 · Cited by 2

Air-blood barrier (ABB) on a chip

Fu, A., Chang, M., Zhu, H., Liu, H., Wu, D., & Zeng, H. (2023) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2023.116919 · Cited by 1

Adopting organoid technology for Co-infections: Innovative solutions for infectious diseases and cancer therapy

Alaeq, R. A., & Mohammedsaeed, W. M. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107938 · Cited by 1

Advanced strategies in organoids for metabolic monitoring and metabolic disease modeling

Ma, W., Xu, Y., Gu, Z., & Li, D. (2025) · Nano Research · doi:10.26599/nr.2025.94907988 · Cited by 1

Advances in lung biomimetic systems: exploring biophysical cues in lung regenerative medicine

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Zhao, W., Wang, Y., Chen, T., Shen, M., Wang, J., Huang, X., Zhu, L., Yu, T., Zhang, Z., Yang, Y., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102653 · Cited by 2

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Lim, S., Kim, S. H., Hye‐Jin, J., Park, S., Koo, B., Lee, J., & Shin, W. (2026) · FEBS Letters · doi:10.1002/1873-3468.70272 · Cited by 2

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Zhou, Z., Qi, Z., Lei, C., Dong, Y., Zhang, J., Liu, Y., Zhao, Y., & He, S. (2025) · Advanced technology in neuroscience . · doi:10.4103/atn.atn-d-25-00006 · Cited by 1

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Losakul, R., Voitiuk, K., Xu, R., Seiler, S. T., Yurevych, V., Yuzvinsky, T. D., Wang, A. Y.-D., Pačar, I., Haussler, D. H., Salama, S. R., et al. (2026) · IEEE Journal of Selected Topics in Quantum Electronics · doi:10.1109/jstqe.2026.3672359 · Cited by 1

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Shin, M., Lee, M.-J., Lee, S., Lee, K., & Choi, J.-W. (2026) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2026.118612 · Cited by 1

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Xu, X., Zhang, W., Qian, J., Gu, X., Fan, S., Niu, Q., Reis, R. L., Kundu, S. C., Yao, X., & Zhang, Y. (2026) · Acta Biomaterialia · doi:10.1016/j.actbio.2026.04.014 · Cited by 1

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Topal, T. (2026) · Methods in molecular biology · doi:10.1007/7651_2026_700 · Cited by 1

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Yang, J., Cheng, C., Luo, W., He, X., Li, Y., Hu, X., Cai, S., Zou, H., Mo, S., & Peng, J. (2026) · MedComm · doi:10.1002/mco2.70741 · Cited by 2

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Ishan, M., JImenez-Macias, J. L., & Read, R. D. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1803705 · Cited by 1

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Yang, Y., Sheng, J., Sheng, F., Liang, X., Ma, C., Chen, R., Wang, S., & Qian, X. (2025) · The Analyst · doi:10.1039/d5an00514k · Cited by 5

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Papamichail, L., Koch, L. S., Veerman, D., Broersen, K., & van der Meer, A. D. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2025.1515340 · Cited by 120

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Suhito, I. R., & Kim, T. P. (2022) · Organoid · doi:10.51335/organoid.2022.2.e4 · Cited by 21

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