Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Wrapp, Daniel, Wang, Nianshuang, Corbett, Kizzmekia S., Goldsmith, Jory A., Hsieh, Ching-Lin, Abiona, Olubukola, Graham, Barney S., McLellan, Jason S.·2020·Science
DOI 10.1126/science.abb2507

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  13. Zoonotic origins of human coronaviruses
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  17. A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2
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  55. Therapeutic strategies for COVID-19: progress and lessons learned
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  56. Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2
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  59. Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum
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  60. Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies
    Lee, Wen Shi, Wheatley, Adam K., Kent, Stephen J., DeKosky, Brandon J. · 2020 · Nature Microbiology
  61. The epidemiology and clinical information about COVID-19
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  62. How COVID-19 induces cytokine storm with high mortality
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  65. Seroprevalence of antibodies to SARS-CoV-2 in 10 sites in the United States, March 23–May 12, 2020
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  70. SARS‐CoV‐2 Seroconversion in Humans: A Detailed Protocol for a Serological Assay, Antigen Production, and Test Setup
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  73. From SARS and MERS to COVID-19: a brief summary and comparison of severe acute respiratory infections caused by three highly pathogenic human coronaviruses
    Zhixing Zhu, Xihua Lian, Xiaoshan Su, Weijing Wu, Giuseppe A. Marraro, Yiming Zeng · 2020 · Respiratory Research
  74. Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
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  75. CryoDRGN: reconstruction of heterogeneous cryo-EM structures using neural networks
    Ellen D. Zhong, Tristan Bepler, Bonnie Berger, Joseph H. Davis · 2021 · Nature Methods
  76. The Natural History, Pathobiology, and Clinical Manifestations of SARS-CoV-2 Infections
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  79. Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
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  80. Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks
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  81. Advances in COVID-19 mRNA vaccine development
    Fang, Enyue, Liu, Xiaohui, Li, Miao, Zhang, Zelun, Song, Lifang, Zhu, Baiyu, Wu, Xiaohong, Liu, Jingjing, Zhao, Danhua, Li, Yuhua · 2022 · Signal Transduction and Targeted Therapy
  82. Immunogenicity of a DNA vaccine candidate for COVID-19
    Smith, Trevor R. F., Patel, Ami, Ramos, Stephanie, Elwood, Dustin, Zhu, Xizhou, Yan, Jian, Gary, Ebony N., Walker, Susanne N., Schultheis, Katherine, Purwar, Mansi et al. · 2020 · Nature Communications
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  100. Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
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