Immune response, inflammation, and the clinical spectrum of COVID-19

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884 · see citing works

Clinical characteristics of coronavirus disease 2019 in China

Guan, W.-J., Ni, Z.-Y., Hu, Y., Liang, W.-H., Ou, C.-Q., He, J.-X., Liu, L., Shan, H., Lei, C.-L., Hui, D. S. C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2002032 · Cited by 30,246 · see citing works

A pneumonia outbreak associated with a new coronavirus of probable bat origin

Zhou, P., Yang, X.-L., Wang, X.-G., Hu, B., Zhang, L., Zhang, W., Si, H.-R., Zhu, Y., Li, B., Huang, C.-L., et al. (2020) · Nature · doi:10.1038/s41586-020-2012-7 · Cited by 21,969 · see citing works

Epidemiological and clinical characteristics of 99 cases of 2019 novel Coronavirus pneumonia in Wuhan, China: a descriptive study.

Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415 · see citing works

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.052 · Cited by 20,286 · see citing works

Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia

Li, Q., Guan, X., Wu, P., Wang, X., Zhou, L., Tong, Y., Ren, R., Leung, K. S. M., Lau, E. H. Y., Wong, J. Y., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001316 · Cited by 16,575 · see citing works

A new coronavirus associated with human respiratory disease in China

Wu, F., Zhao, S., Yu, B., Chen, Y.-M., Wang, W., Song, Z.-G., Hu, Y., Tao, Z.-W., Tian, J.-H., Pei, Y.-Y., et al. (2020) · Nature · doi:10.1038/s41586-020-2008-3 · Cited by 11,688 · see citing works

COVID-19: consider cytokine storm syndromes and immunosuppression

Mehta, P., McAuley, D. F., Brown, M., Sanchez, E., Tattersall, R. S., & Manson, J. J. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30628-0 · Cited by 9,664 · see citing works

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Wrapp, D., Wang, N., Corbett, K. S., Goldsmith, J. A., Hsieh, C.-L., Abiona, O., Graham, B. S., & McLellan, J. S. (2020) · Science · doi:10.1126/science.abb2507 · Cited by 8,897 · see citing works

Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein

Walls, A. C., Park, Y.-J., Tortorici, M. A., Wall, A., McGuire, A. T., & Veesler, D. (2020) · doi:10.1101/2020.02.19.956581 · Cited by 8,586 · see citing works

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

Xu, Z., Shi, L., Wang, Y., Zhang, J., Huang, L., Zhang, C., Liu, S., Zhao, P., Liu, H., Zhu, L., et al. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30076-x · Cited by 8,545 · see citing works

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

Wu, C., Chen, X., Cai, Y., Xia, J., Zhou, X., Xu, S., Huang, H., Zhang, L., Zhou, X., Du, C., et al. (2020) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2020.0994 · Cited by 8,249 · see citing works

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Lan, J., Ge, J., Yu, J., Shan, S., Zhou, H., Fan, S., Zhang, Q., Shi, X., Wang, Q., Zhang, L., et al. (2020) · Nature · doi:10.1038/s41586-020-2180-5 · Cited by 5,983 · see citing works

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis

Hamming, I., Timens, W., Bulthuis, M., Lely, A., Navis, G., & van Goor, H. (2004) · The Journal of Pathology · doi:10.1002/path.1570 · Cited by 5,676 · see citing works

The proximal origin of SARS-CoV-2

Andersen, K. G., Rambaut, A., Lipkin, W. I., Holmes, E. C., & Garry, R. F. (2020) · Nature Medicine · doi:10.1038/s41591-020-0820-9 · Cited by 5,081 · see citing works

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

Yan, R., Zhang, Y., Li, Y., Xia, L., Guo, Y., & Zhou, Q. (2020) · Science · doi:10.1126/science.abb2762 · Cited by 4,950 · see citing works

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

Qin, C., Zhou, L., Hu, Z., Zhang, S., Yang, S., Tao, Y., Xie, C., Ma, K., Shang, K., Wang, W., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa248 · Cited by 4,775 · see citing works

Clinical and immunological features of severe and moderate coronavirus disease 2019

Chen, G., Wu, D., Guo, W., Cao, Y., Huang, D., Wang, H., Wang, T., Zhang, X., Chen, H., Yu, H., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci137244 · Cited by 4,750 · see citing works

The trinity of COVID-19: immunity, inflammation and intervention

Tay, M. Z., Poh, C. M., Rénia, L., MacAry, P. A., & Ng, L. F. P. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0311-8 · Cited by 4,360 · see citing works

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Blanco-Melo, D., Nilsson-Payant, B. E., Liu, W.-C., Uhl, S., Hoagland, D., Møller, R., Jordan, T. X., Oishi, K., Panis, M., Sachs, D., et al. (2020) · Cell · doi:10.1016/j.cell.2020.04.026 · Cited by 4,222 · see citing works

Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis

Yang, J., Zheng, Y., Gou, X., Pu, K., Chen, Z., Guo, Q., Ji, R., Wang, H., Wang, Y., & Zhou, Y. (2020) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2020.03.017 · Cited by 4,206 · see citing works

Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study

Chen, T., Wu, D., Chen, H., Yan, W., Yang, D., Chen, G., Ma, K., Xu, D., Yu, H., Wang, H., et al. (2020) · BMJ · doi:10.1136/bmj.m1091 · Cited by 3,903 · see citing works

Structural basis of receptor recognition by SARS-CoV-2

Shang, J., Ye, G., Shi, K., Wan, Y., Luo, C., Aihara, H., Geng, Q., Auerbach, A., & Li, F. (2020) · Nature · doi:10.1038/s41586-020-2179-y · Cited by 3,661 · see citing works

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2)

Li, R., Pei, S., Chen, B., Song, Y., Zhang, T., Yang, W., & Shaman, J. (2020) · Science · doi:10.1126/science.abb3221 · Cited by 3,633 · see citing works

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., Huan, Y., Yang, P., Zhang, Y., Deng, W., et al. (2005) · Nature Medicine · doi:10.1038/nm1267 · Cited by 3,445 · see citing works

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

Letko, M., Marzi, A., & Munster, V. (2020) · Nature Microbiology · doi:10.1038/s41564-020-0688-y · Cited by 3,109 · see citing works

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Ou, X., Liu, Y., Lei, X., Li, P., Mi, D., Ren, L., Guo, L., Guo, R., Chen, T., Hu, J., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15562-9 · Cited by 3,097 · see citing works

Emerging coronaviruses: Genome structure, replication, and pathogenesis

Chen, Y. Z., Liu, Q., & Guo, D. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25681 · Cited by 3,069 · see citing works

Early dynamics of transmission and control of COVID-19: a mathematical modelling study

Kucharski, A. J., Russell, T., Diamond, C., Liu, Y., Edmunds, J., Funk, S., Eggo, R. M., Sun, F., Jit, M., Munday, J. D., et al. (2020) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(20)30144-4 · Cited by 2,675 · see citing works

Effective treatment of severe COVID-19 patients with tocilizumab

Xu, X., Han, M., Li, T., Sun, W., Wang, D., Fu, B., Zhou, Y., Zheng, X., Yang, Y., Li, X., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2005615117 · Cited by 2,636 · see citing works

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Liao, M., Liu, Y., Yuan, J., Wen, Y., Xu, G., Zhao, J., Cheng, L., Li, J., Wang, X., Wang, F., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0901-9 · Cited by 2,614 · see citing works

Pathogenic human coronavirus infections: Causes and consequences of cytokine storm and immunopathology

Channappanavar, R., & Perlman, S. (2017) · Seminars in Immunopathology · doi:10.1007/s00281-017-0629-x · Cited by 2,524 · see citing works

Angiotensin-converting enzyme 2 protects from severe acute lung failure

Imai, Y., Kuba, K., Rao, S., Huan, Y., Guo, F., Guan, B., Yang, P., Sarao, R., Wada, T., Leong-Poi, H., et al. (2005) · Nature · doi:10.1038/nature03712 · Cited by 2,453 · see citing works

Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)

Sanders, J. M., Monogue, M. L., Jodlowski, T. Z., & Cutrell, J. B. (2020) · JAMA · doi:10.1001/jama.2020.6019 · Cited by 2,357 · see citing works

Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adults

Ludvigsson, J. F. (2020) · Acta Paediatrica · doi:10.1111/apa.15270 · Cited by 2,313 · see citing works

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection

Zou, X., Chen, K., Zou, J., Han, P., Hao, J., & Han, Z. (2020) · Frontiers of Medicine · doi:10.1007/s11684-020-0754-0 · Cited by 2,287 · see citing works

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

Shen, C., Wang, Z., Zhao, F., Yang, Y., Li, J., Yuan, J., Wang, F., Li, D., Yang, M., Xing, L., et al. (2020) · JAMA · doi:10.1001/jama.2020.4783 · Cited by 2,278 · see citing works

Covid-19 — Navigating the Uncharted

Fauci, A. S., Lane, H. C., & Redfield, R. (2020) · New England Journal of Medicine · doi:10.1056/nejme2002387 · Cited by 1,983 · see citing works

Coronavirus infections and immune responses

Li, G., Fan, Y., Lai, Y., Han, T., Li, Z., Zhou, P., Pan, P., Wang, W., Hu, D., Liu, X., et al. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25685 · Cited by 1,963 · see citing works

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

Zheng, M., Gao, Y., Wang, G., Song, G., Liu, S., Sun, D., Xu, Y., & Tian, Z. (2020) · Cellular & Molecular Immunology · doi:10.1038/s41423-020-0402-2 · Cited by 1,768 · see citing works

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

Tai, W., He, L., Zhang, X., Pu, J., Voronin, D., Jiang, S., Zhou, Y., & Du, L. (2020) · Cellular & Molecular Immunology · doi:10.1038/s41423-020-0400-4 · Cited by 1,654 · see citing works

Severe Acute Respiratory Syndrome Coronavirus 2−Specific Antibody Responses in Coronavirus Disease Patients

Okba, N. M. A., Müller, M. A., Li, W., Wang, C., GeurtsvanKessel, C. H., Corman, V. M., Lamers, M. M., Sikkema, R. S., de Bruin, E., Chandler, F. D., et al. (2020) · Emerging Infectious Diseases · doi:10.3201/eid2607.200841 · Cited by 1,614 · see citing works

COVID-19: immunopathology and its implications for therapy

Cao, X. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0308-3 · Cited by 1,609 · see citing works

COVID-19 infection: the perspectives on immune responses

Shi, Y., Wang, Y., Shao, C., Huang, J., Gan, J., Huang, X., Bucci, E. M., Piacentini, M., Ippolito, G., & Melino, G. (2020) · Cell Death and Differentiation · doi:10.1038/s41418-020-0530-3 · Cited by 1,602 · see citing works

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Wang, K., Chen, W., Zhang, Z., Deng, Y., Lian, J., Du, P. F., Wei, D., Yang, Z., Sun, X., Gong, L., et al. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00426-x · Cited by 1,592 · see citing works

Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19)

Guo, L., Ren, L., Yang, S., Xiao, M., Chang, D., Yang, F., Cruz, C. S. D., Wang, Y., Wu, C., Xiao, Y., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa310 · Cited by 1,585 · see citing works

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

Zhu, F.-C., Li, Y.-H., Guan, X.-H., Hou, L.-H., Wang, W.-J., Li, J.-X., Wu, S.-P., Wang, B.-S., Wang, Z., Wang, L., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31208-3 · Cited by 1,382 · see citing works

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Zhou, Y., Fu, B., Zheng, X., Wang, D., Zhao, C., Qi, Y., Sun, R., Tian, Z., Xu, X., & Wei, H. (2020) · National Science Review · doi:10.1093/nsr/nwaa041 · Cited by 1,295 · see citing works

SARS-CoV-2: a storm is raging

Pedersen, S. F., & Ho, Y.-C. (2020) · Journal of Clinical Investigation · doi:10.1172/jci137647 · Cited by 1,137 · see citing works

SARS-CoV-2 Vaccines: Status Report

Amanat, F., & Krammer, F. (2020) · Immunity · doi:10.1016/j.immuni.2020.03.007 · Cited by 1,120 · see citing works

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

Xiong, Y., Liu, Y., Cao, L., Wang, D., Guo, M., Jiang, A., Guo, D., Hu, W., Yang, J., Tang, Z., et al. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1747363 · Cited by 1,076 · see citing works

Age-dependent dysregulation of innate immunity

Shaw, A. C., Goldstein, D. R., & Montgomery, R. R. (2013) · Nature Reviews Immunology · doi:10.1038/nri3547 · Cited by 1,061 · see citing works

Convalescent plasma as a potential therapy for COVID-19

Chen, L., Xiong, J., Bao, L., & Shi, Y. (2020) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(20)30141-9 · Cited by 1,038 · see citing works

A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity

Huang, A. T., Garcia-Carreras, B., Hitchings, M. D. T., Yang, B., Katzelnick, L. C., Rattigan, S. M., Borgert, B. A., Moreno, C. A., Solomon, B. D., Trimmer-Smith, L., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18450-4 · Cited by 1,026 · see citing works

A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity

(2020) · Nature Communications · doi:10.1101/2020.04.14.20065771 · Cited by 1,019 · see citing works

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

Thevarajan, I., Nguyen, T. H. O., Koutsakos, M., Druce, J. D., Caly, L., van de Sandt, C. E., Jia, X., Nicholson, S. R., Catton, M. C., Cowie, B., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-0819-2 · Cited by 993 · see citing works

Human Coronavirus: Host-Pathogen Interaction

Fung, T. S., & Liu, D. X. (2019) · Annual Review of Microbiology · doi:10.1146/annurev-micro-020518-115759 · Cited by 964 · see citing works

Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients

Zhou, Z. L., Ren, L., Zhang, L., Zhong, J., Xiao, Y., Jia, Z., Guo, L., Yang, J., Wang, C., Jiang, S., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.04.017 · Cited by 963 · see citing works

A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

Grifoni, A., Sidney, J., Zhang, Y., Scheuermann, R. H., Peters, B., & Sette, A. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.03.002 · Cited by 920 · see citing works

Hypothesis for potential pathogenesis of SARS-CoV-2 infection–a review of immune changes in patients with viral pneumonia

Lin, L., Lu, L., Cao, W., & Li, T. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1746199 · Cited by 909 · see citing works

The convalescent sera option for containing COVID-19

Casadevall, A., & Pirofski, L. (2020) · Journal of Clinical Investigation · doi:10.1172/jci138003 · Cited by 904 · see citing works

Dysregulation of Immune Response in Patients with COVID-19 in Wuhan, ChinaPreprint

Qin, C., Zhou, L., Hu, Z., Zhang, S., Yang, S., Yu, T., Xie, C., Ma, K., Shang, K., Wang, W., et al. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3541136 · Cited by 898 · see citing works

Interleukin‐6 in Covid‐19: A systematic review and meta‐analysis

Coomes, E. A., & Haghbayan, H. (2020) · Reviews in Medical Virology · doi:10.1002/rmv.2141 · Cited by 889 · see citing works

Structure analysis of the receptor binding of 2019-nCoV

Chen, Y., Guo, Y., Pan, Y., & Zhao, Z. J. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.02.071 · Cited by 806 · see citing works

COVID-19: a new virus, but a familiar receptor and cytokine release syndrome

Hirano, T., & Murakami, M. (2020) · Immunity · doi:10.1016/j.immuni.2020.04.003 · Cited by 772 · see citing works

The clinical pathology of severe acute respiratory syndrome (SARS): a report from China

Ding, Y., Wang, H., Shen, H., Li, Z., Geng, J., Han, H.-X., Cai, J., Li, X., Kang, W., Weng, D., et al. (2003) · The Journal of Pathology · doi:10.1002/path.1440 · Cited by 765 · see citing works

SARS-CoV-2 invades host cells via a novel route: CD147-spike proteinPreprint

Wang, K., Chen, W., Zhou, Y., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.14.988345 · Cited by 698 · see citing works

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2

Liu, Z., Xiao, X., Wei, X., Li, J., Yang, J., Tan, H., Zhu, J., Zhang, Q., Wu, J., & Liu, L. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25726 · Cited by 684 · see citing works

COVID-19: Immunology and treatment options

Felsenstein, S., Herbert, J. A., McNamara, P. S., & Hedrich, C. M. (2020) · Clinical Immunology · doi:10.1016/j.clim.2020.108448 · Cited by 669 · see citing works

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry

Wan, Y., Shang, J., Sun, S., Tai, W., Chen, J., Geng, Q., He, L., Chen, Y., Wu, J., Shi, Z., et al. (2019) · Journal of Virology · doi:10.1128/jvi.02015-19 · Cited by 667 · see citing works

Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19

Chu, H., Chan, J. F., Wang, Y., Yuen, T. T., Chai, Y., Hou, Y., Shuai, H., Yang, D., Hu, B., Huang, X., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa410 · Cited by 659 · see citing works

Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

Huang, I., Bailey, C. C., Weyer, J. L., Radoshitzky, S. R., Becker, M. M., Chiang, J. J., Brass, A. L., Ahmed, A. A., Chī, X., Dŏng, L., et al. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1001258 · Cited by 604 · see citing works

Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26

Vankadari, N., & Wilce, M. C. J. (2020) · Emerging Microbes & Infections · doi:10.1080/22221751.2020.1739565 · Cited by 588 · see citing works

Spatial map of human T cell compartmentalization and maintenance over decades of life

Thome, J. J. C., Yudanin, N., Ohmura, Y., Kubota, M., Grinshpun, B., Sathaliyawala, T., Kato, T., Lerner, H., Shen, Y., & Farber, D. L. (2014) · Cell · doi:10.1016/j.cell.2014.10.026 · Cited by 587 · see citing works

Characteristics of lymphocyte subsets and cytokines in peripheral blood of 123 hospitalized patients with 2019 novel coronavirus pneumonia (NCP)

Wan, S., Yi, Q., Fan, S., Lv, J., Zhang, X., Guo, L., Lang, C., Xiao, Q., Xiao, K., Yi, Z., et al. (2020) · doi:10.1101/2020.02.10.20021832 · Cited by 562 · see citing works

Genomic Diversity of Severe Acute Respiratory Syndrome–Coronavirus 2 in Patients With Coronavirus Disease 2019

Shen, Z., Xiao, Y., Kang, L., Ma, W., Shi, L., Zhang, L., Zhou, Z., Yang, J., Zhong, J., Yang, D., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa203 · Cited by 513 · see citing works

The potential danger of suboptimal antibody responses in COVID-19

Iwasaki, A., & Yang, Y.-X. (2020) · Nature reviews. Immunology · doi:10.1038/s41577-020-0321-6 · Cited by 510 · see citing works

Type 1 interferons as a potential treatment against COVID-19

Sallard, E., Lescure, F.-X., Yazdanpanah, Y., Mentré, F., & Peiffer‐Smadja, N. (2020) · Antiviral Research · doi:10.1016/j.antiviral.2020.104791 · Cited by 508 · see citing works

Immunopathogenesis of coronavirus infections: implications for SARS

Dandekar, A. A., & Perlman, S. M. (2005) · Nature reviews. Immunology · doi:10.1038/nri1732 · Cited by 499 · see citing works

The role of interleukin‐6 in monitoring severe case of coronavirus disease 2019

Liu, T., Zhang, J., Yang, Y., Ma, H., Li, Z., Zhang, J., Cheng, J., Zhang, X., Zhao, Y., Xia, Z., et al. (2020) · EMBO Molecular Medicine · doi:10.15252/emmm.202012421 · Cited by 498 · see citing works

Lack of Peripheral Memory B Cell Responses in Recovered Patients with Severe Acute Respiratory Syndrome: A Six-Year Follow-Up Study

Tang, F., Quan, Y., Xin, Z.-T., Wrammert, J., Ma, M.-J., Lv, H., Wang, T.-B., Yang, H., Richardus, J. H., Liu, W., et al. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.0903490 · Cited by 496 · see citing works

pH-Dependent Entry of Severe Acute Respiratory Syndrome Coronavirus Is Mediated by the Spike Glycoprotein and Enhanced by Dendritic Cell Transfer through DC-SIGN

Yang, Z., Huang, Y. M., Lakshmanan, G., Leung, K., Kong, W., Schwartz, O., Subbarao, K., & Nabel, G. J. (2004) · Journal of Virology · doi:10.1128/jvi.78.11.5642-5650.2004 · Cited by 488 · see citing works

Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies

Yi, C., Sun, X., Ye, J., Ding, L., Liu, M., Yang, Z., Lü, X., Zhang, Y., Ma, L., Gu, W., et al. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0458-z · Cited by 479 · see citing works

Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19

Zhang, H., Zhou, P., Wei, Y., Yue, H., Wang, Y., Hu, M., Zhang, S., Cao, T., Yang, H., Li, M., et al. (2020) · Annals of Internal Medicine · doi:10.7326/m20-0533 · Cited by 474 · see citing works

SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome

Shi, C.-S., Qi, H.-Y., Boularan, C., Huang, N., Abu-Asab, M. S., Shelhamer, J. H., & Kehrl, J. H. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1303196 · Cited by 469 · see citing works

Is COVID-19 receiving ADE from other coronaviruses?

Tetro, J. A. (2020) · Microbes and Infection · doi:10.1016/j.micinf.2020.02.006 · Cited by 437 · see citing works

Evolutionary history, potential intermediate animal host, and cross‐species analyses of SARS‐CoV‐2

Li, X., Zai, J., Zhao, Q., Nie, Q. H., Li, Y., Foley, B. T., & Chaillon, A. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25731 · Cited by 428 · see citing works

Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses

Wang, N., Shang, J., Jiang, S., & Du, L. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00298 · Cited by 424 · see citing works

Double-Stranded RNA Sensors and Modulators in Innate Immunity

Hur, S. (2019) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042718-041356 · Cited by 420 · see citing works

Senescence-associated inflammatory responses: aging and cancer perspectives

Lasry, A., & Ben-Neriah, Y. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.02.009 · Cited by 408 · see citing works

Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

He, Y., Zhou, Y., Liu, S., Kou, Z., Li, W., Farzan, M., & Jiang, S. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.09.106 · Cited by 400 · see citing works

Clinicopathologic, Immunohistochemical, and Ultrastructural Findings of a Fatal Case of Middle East Respiratory Syndrome Coronavirus Infection in the United Arab Emirates, April 2014

Ng, D. L., Hosani, F. I. A., Keating, M. K., Gerber, S. I., Jones, T. L., Metcalfe, M. G., Tong, S., Tao, Y., Alami, N. N., Haynes, L. M., et al. (2016) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.10.024 · Cited by 384 · see citing works

Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

Raoult, D., Zumla, A. I., Locatelli, F., Ippolito, G., & Kroemer, G. (2020) · Cell Stress · doi:10.15698/cst2020.04.216 · Cited by 381 · see citing works

Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

Luan, J., Lu, Y., Jin, X., & Zhang, L. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.03.047 · Cited by 379 · see citing works

Report from the American Society for Microbiology COVID-19 International Summit, 23 March 2020: Value of Diagnostic Testing for SARS–CoV-2/COVID-19

Patel, R., Babady, E., Theel, E. S., Storch, G. A., Pinsky, B. A., George, K. S., Smith, T. C., & Bertuzzi, S. (2020) · mBio · doi:10.1128/mbio.00722-20 · Cited by 371 · see citing works

Developing antibody tests for SARS-CoV-2

Petherick, A. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30788-1 · Cited by 364 · see citing works

Why is COVID‐19 so mild in children?

Brodin, P. (2020) · Acta Paediatrica · doi:10.1111/apa.15271 · Cited by 350 · see citing works

Naive T Cell Maintenance and Function in Human Aging

Goronzy, J. J., Fang, F., Cavanagh, M., Qi, Q., & Weyand, C. M. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1500046 · Cited by 348 · see citing works

Association of HLA class I with severe acute respiratory syndrome coronavirus infection

Lin, M., Tseng, H.-K., Tréjaut, J., Lee, H.-L., Loo, J.-H., Chu, C. C., Chen, P.-J., Su, Y.-W., Lim, K. H., Tsai, Z.-U., et al. (2003) · BMC Medical Genetics · doi:10.1186/1471-2350-4-9 · Cited by 328 · see citing works

Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcγR Pathway

Jaume, M., Yip, M., Cheung, C. Y., Leung, N., Li, P. H., Kien, F., Dutry, I., Callendret, B., Escriou, N., Altmeyer, R. M., et al. (2011) · Journal of Virology · doi:10.1128/jvi.00671-11 · Cited by 312 · see citing works

The Role of Antibody Testing for SARS-CoV-2: Is There One?

Theel, E. S., Slev, P. R., Wheeler, S., Couturier, M. R., Wong, S. J., & Kadkhoda, K. (2020) · Journal of Clinical Microbiology · doi:10.1128/jcm.00797-20 · Cited by 303 · see citing works

A Dynamic Immune Response Shapes COVID-19 Progression

Ong, E. Z., Chan, Y. F. Z., Leong, W. Y., Lee, N. M. Y., Kalimuddin, S., Mohideen, S. M. H., Chan, K. S., Tan, A. T., Bertoletti, A., Ooi, E. E., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.03.021 · Cited by 290 · see citing works

Drivers of age‐related inflammation and strategies for healthspan extension

Goldberg, E. L., & Dixit, V. D. (2015) · Immunological Reviews · doi:10.1111/imr.12295 · Cited by 274 · see citing works

Recovery from the Middle East respiratory syndrome is associated with antibody and T cell responses

Zhao, J., Alshukairi, A. N., Baharoon, S. A., Ahmed, W., Bokhari, A. A., Nehdi, A., Layqah, L. A., Alghamdi, M., Algethamy, M., Dada, A. M., et al. (2017) · Science Immunology · doi:10.1126/sciimmunol.aan5393 · Cited by 263 · see citing works

Aging of the T Cell Compartment in Mice and Humans: From No Naive Expectations to Foggy Memories

Nikolich-Žugich, J. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1401174 · Cited by 259 · see citing works

Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020

Haveri, A., Smura, T., Kuivanen, S. H., Österlund, P., Hepojoki, J., Ikonen, N., Pitkäpaasi, M., Blomqvist, S., Rönkkö, E., Kantele, A., et al. (2020) · Eurosurveillance · doi:10.2807/1560-7917.es.2020.25.11.2000266 · Cited by 255 · see citing works

The Immunobiology of SARS

Chen, J., & Subbarao, K. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141706 · Cited by 252 · see citing works

Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus

Yip, M., Leung, N., Cheung, C. Y., Li, P. H., Lee, H. H. Y., Daëron, M., Peiris, M. J. S., Bruzzone, R., & Jaume, M. (2014) · Virology Journal · doi:10.1186/1743-422x-11-82 · Cited by 249 · see citing works

Interleukin-6 in COVID-19: A Systematic Review and Meta-AnalysisPreprint

Coomes, E. A., & Haghbayan, H. (2020) · medRxiv · doi:10.1101/2020.03.30.20048058 · Cited by 238 · see citing works

Identification of a Receptor-Binding Domain of the Spike Glycoprotein of Human Coronavirus HCoV-229E

Bonavia, A., Zelus, B. D., Wentworth, D. E., Talbot, P. J., & Holmes, K. V. (2003) · Journal of Virology · doi:10.1128/jvi.77.4.2530-2538.2003 · Cited by 194 · see citing works

The Promise and Peril of Antibody Testing for COVID-19

Abbasi, J. (2020) · JAMA · doi:10.1001/jama.2020.6170 · Cited by 184 · see citing works

The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencingPreprint

Liao, M., Liu, Y., Yuan, J., et al. (2020) · medRxiv · doi:10.1101/2020.02.23.20026690 · Cited by 178 · see citing works

COVID-19 as an Acute Inflammatory Disease

Manjili, R. H., Zarei, M., Habibi, M., & Manjili, M. H. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000413 · Cited by 176 · see citing works

Pathogenesis of severe acute respiratory syndrome

Lau, Y., & Peiris, M. J. S. (2005) · Current Opinion in Immunology · doi:10.1016/j.coi.2005.05.009 · Cited by 168 · see citing works

Association of Human‐Leukocyte‐Antigen Class I (B*0703) and Class II (DRB1*0301) Genotypes with Susceptibility and Resistance to the Development of Severe Acute Respiratory Syndrome

Ng, M. H. L., Lau, K., Li, L., Cheng, S., Chan, W. Y., Hui, P. K., Zee, B. C.-Y., Leung, C., & Sung, J. J. �. (2004) · The Journal of Infectious Diseases · doi:10.1086/421523 · Cited by 168 · see citing works

The potential role of IL-6 in monitoring severe case of coronavirus disease 2019Preprint

Liu, T., Zhang, J., Yang, Y., et al. (2020) · medRxiv · doi:10.1101/2020.03.01.20029769 · Cited by 160 · see citing works

Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry

Shang, J., Wan, Y., Liu, C., Yount, B. L., Gully, K. L., Yang, Y., Auerbach, A. A., Peng, G., Baric, R. S., & Li, F. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008392 · Cited by 154 · see citing works

Avoiding pitfalls in the pursuit of a COVID-19 vaccine

Peeples, L. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2005456117 · Cited by 152 · see citing works

An Outbreak of Human Coronavirus OC43 Infection and Serological Cross‐Reactivity with SARS Coronavirus

Patrick, D. M., Petric, M., Skowronski, D. M., Guasparini, R., Booth, T. F., Krajden, M., McGeer, P. L., Bastien, N., Gustafson, L., Dubord, J., et al. (2006) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2006/152612 · Cited by 152 · see citing works

Understanding the T cell immune response in SARS coronavirus infection

Oh, H. J., Gan, S. K., Bertoletti, A., & Tan, Y. (2012) · Emerging Microbes & Infections · doi:10.1038/emi.2012.26 · Cited by 152 · see citing works

Risk factors associated with disease progression in a cohort of patients infected with the 2019 novel coronavirus

Zhou, Y., Zhang, Z., Tian, J., & Xiong, S. (2020) · Annals of Palliative Medicine · doi:10.21037/apm.2020.03.26 · Cited by 144 · see citing works

Neutralizing Antibody Response and SARS Severity

Ho, M., Chen, W., Chen, H., Lin, S.-F., Wang, M.-C., Di, J., Lu, Y., Liu, C., Chang, S., Chao, C.-L., et al. (2005) · Emerging infectious diseases · doi:10.3201/eid1111.040659 · Cited by 138 · see citing works

Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection

Du, L., Zhao, G., Lin, Y., Sui, H., Chan, C. C. S., Ma, S., He, Y., Jiang, S., Wu, C. Y., Yuen, K., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.2.948 · Cited by 136 · see citing works

Human-Leukocyte Antigen Class I Cw 1502 and Class II DR 0301 Genotypes Are Associated with Resistance to Severe Acute Respiratory Syndrome (SARS) Infection

Wang, S., Chen, K.-H., Chen, M., Li, W.-Y., Chen, Y., Tsao, C.-H., Yen, M., Huang, J. C., & Chen, Y. A. (2011) · Viral Immunology · doi:10.1089/vim.2011.0024 · Cited by 132 · see citing works

Discovery of Bat Coronaviruses through Surveillance and Probe Capture-Based Next-Generation Sequencing

Li, B., Si, H.-R., Zhu, Y., Yang, X., Anderson, D. E., Shi, Z., Wang, L., & Zhou, P. (2020) · mSphere · doi:10.1128/msphere.00807-19 · Cited by 119 · see citing works

Characterization of lung inflammation and its impact on macrophage function in aging

Canan, C., Gokhale, N. S., Carruthers, B., Lafuse, W. P., Schlesinger, L., Torrelles, J., & Turner, J. (2014) · Journal of Leukocyte Biology · doi:10.1189/jlb.4a0214-093rr · Cited by 106 · see citing works

An Inflammatory Profile Correlates With Decreased Frequency of Cytotoxic Cells in Coronavirus Disease 2019

Bordoni, V., Sacchi, A., Cimini, E., Notari, S., Grassi, G., Tartaglia, E., Casetti, R., Giancola, M. L., Bevilacqua, N., Maeurer, M. J., et al. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa577 · Cited by 105 · see citing works

Effect of mucosal and systemic immunization with virus‐like particles of severe acute respiratory syndrome coronavirus in mice

Lu, B., Huang, Y. P., Huang, L., Bao, L., Zheng, Z., Chen, Z., Chen, J., Hu, Q., & Wang, H. (2010) · Immunology · doi:10.1111/j.1365-2567.2010.03231.x · Cited by 97 · see citing works

Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19Preprint

Patterson, B. K., Seethamraju, H., Dhody, K., Corley, M. J., Kazempour, K., Lalezari, J., Pang, A. P. S., Sugai, C. K., Francisco, E. B., Pise, A., et al. (2020) · medRxiv · doi:10.1101/2020.05.02.20084673 · Cited by 92 · see citing works

Weak Induction of Interferon Expression by Severe Acute Respiratory Syndrome Coronavirus 2 Supports Clinical Trials of Interferon-λ to Treat Early Coronavirus Disease 2019

OʼBrien, T. R., Thomas, D. L., Jackson, S. S., Prokunina‐Olsson, L., Donnelly, R. P., & Hartmann, R. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa453 · Cited by 88 · see citing works

ACE2 Gene Polymorphisms Do Not Affect Outcome of Severe Acute Respiratory Syndrome

Chiu, R. W. K., Tang, N. L. S., Hui, D. S. C., Chung, G. T., Chim, S. S. C., Chan, K. C. A., Sung, Y.-M., Chan, L. Y., Tong, Y., Lee, W.-S., et al. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.035436 · Cited by 83 · see citing works

The ER stress sensor IRE1 and MAP kinase ERK modulate autophagy induction in cells infected with coronavirus infectious bronchitis virus

Fung, T. S., & Liu, D. X. (2019) · Virology · doi:10.1016/j.virol.2019.05.002 · Cited by 71 · see citing works

The phenotypic changes of γδ T cells in COVID‐19 patients

Lei, L., 钱宏波, Yang, X., 周晓勃, Zhang, D., Zhang, D., Dai, T., Guo, R., Shi, L., Cheng, Y., et al. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15620 · Cited by 70 · see citing works

Primary Severe Acute Respiratory Syndrome Coronavirus Infection Limits Replication but Not Lung Inflammation upon Homologous Rechallenge

Clay, C. C., Donart, N., Fomukong, N. G., Knight, J. B., Lei, W., Price, L., Hahn, F. F., Westrienen, J. V., & Harrod, K. S. (2012) · Journal of Virology · doi:10.1128/jvi.06791-11 · Cited by 64 · see citing works

Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain

Shim, B.-S., Stadler, K., Nguyen, H. H., Yun, C., Kim, D. W., Chang, J., Czerkinsky, C. C., & Song, M. (2012) · Virology Journal · doi:10.1186/1743-422x-9-215 · Cited by 51 · see citing works

An exclusive 42 amino acid signature in pp1ab protein provides insights into the evolutive history of the 2019 novel human‐pathogenic coronavirus (SARS‐CoV‐2)

Cárdenas‐Conejo, Y., Liñán-Rico, A., García-Rodríguez, D., Centeno‐Leija, S., & Serrano‐Posada, H. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25758 · Cited by 47 · see citing works

Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2

Wen, F., Yu, H., Guo, J., Li, Y., Luo, K., & Huang, S. (2020) · Journal of Infection · doi:10.1016/j.jinf.2020.02.027 · Cited by 46 · see citing works

Lack of association between HLA‐A, ‐B and ‐DRB1 alleles and the development of SARS: a cohort of 95 SARS‐recovered individuals in a population of Guangdong, southern China

Xiong, P., Zeng, X., Song, M., Jia, S., Zhong, M. H., Xiao, L., Lan, W., Cai, C., Wu, X., Gong, F., et al. (2008) · International Journal of Immunogenetics · doi:10.1111/j.1744-313x.2007.00741.x · Cited by 37 · see citing works

Immunogenetics in SARS: a case-control study.

Ng, M. H. L., Cheng, S. H., Lau, K., Leung, G. M., Khoo, U., Zee, B. C.-Y., & Sung, J. J. �. (2010) · PubMed · Cited by 29 · see citing works

Good IgA Bad IgG in SARS-CoV-2 Infection?

Béné, M. C., Bittencourt, M. D. C., Eveillard, M., & Bris, Y. L. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa426 · Cited by 24 · see citing works

A Glimpse Into the Origins of Genetic Diversity in the Severe Acute Respiratory Syndrome Coronavirus 2

Wertheim, J. O. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa213 · Cited by 13 · see citing works

Correction for Li et al., “Discovery of Bat Coronaviruses through Surveillance and Probe Capture-Based Next-Generation Sequencing”

Li, B., Si, H.-R., Zhu, Y., Yang, X., Anderson, D. E., Shi, Z., Wang, L., & Zhou, P. (2020) · mSphere · doi:10.1128/msphere.00170-20 · Cited by 10 · see citing works

Biphasic Outbreak of Invasive Group A Streptococcus Disease in Eldercare Facility, New Zealand

Worthing, K. A., Werno, A., Pink, R., McIntyre, L. C., Carter, G. P., Williamson, D. A., & Davies, M. R. (2020) · Emerging infectious diseases · doi:10.3201/eid2605.190131 · Cited by 10 · see citing works

SARS-CoV2 vaccines: Slow is fast

Green, D. R. (2020) · Science Advances · doi:10.1126/sciadv.abc7428 · Cited by 9 · see citing works

IL-6 in inflammation, autoimmunity and cancer

Hirano, T. (2021) · International Immunology · doi:10.1093/intimm/dxaa078 · Cited by 1,453 · see citing works

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

Zhu, F.-C., Li, Y.-H., Guan, X.-H., Hou, L.-H., Wang, W.-J., Li, J.-X., Wu, S.-P., Wang, B.-S., Wang, Z., Wang, L., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31208-3 · Cited by 1,382 · see citing works

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2

Liu, Z., Xiao, X., Wei, X., Li, J., Yang, J., Tan, H., Zhu, J., Zhang, Q., Wu, J., & Liu, L. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25726 · Cited by 684 · see citing works

Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses

Wang, N., Shang, J., Jiang, S., & Du, L. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00298 · Cited by 424 · see citing works

SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation

Li, S., Zhang, Y., Guan, Z., Li, H., Ye, M., Chen, X., Shen, J., Zhou, Y., Shi, Z.-L., Zhou, P., et al. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00334-0 · Cited by 365 · see citing works

SARS-CoV-2, COVID-19 and the aging immune system

Bartleson, J. M., Radenkovic, D., Covarrubias, A. J., Furman, D., Winer, D. A., & Verdin, E. (2021) · Nature Aging · doi:10.1038/s43587-021-00114-7 · Cited by 359 · see citing works

Diagnostic performance of different sampling approaches for SARS-CoV-2 RT-PCR testing: a systematic review and meta-analysis

Tsang, N. N. Y., So, H. C., Ng, K. Y., Cowling, B. J., Leung, G. M., & Ip, D. (2021) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(21)00146-8 · Cited by 288 · see citing works

COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies

Rawat, K., Kumari, P., & Saha, L. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173751 · Cited by 276 · see citing works

The Role of Vitamin C, Vitamin D, and Selenium in Immune System against COVID-19

Bae, M., & Kim, H. (2020) · Molecules · doi:10.3390/molecules25225346 · Cited by 259 · see citing works

Chemokines and chemokine receptors during COVID-19 infection

Khalil, B. A., Elemam, N. M., & Maghazachi, A. A. (2021) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2021.01.034 · Cited by 246 · see citing works

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

Nagelkerke, A., Ojansivu, M., van der Koog, L., Whittaker, T. E., Cunnane, E. M., da Silva, A. M., Dekker, N., & Stevens, M. M. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.04.013 · Cited by 208 · see citing works

T‐cell responses and therapies against SARS‐CoV‐2 infection

Toor, S. M., Saleh, R., Nair, V. S., Taha, R. Z., & Elkord, E. (2020) · Immunology · doi:10.1111/imm.13262 · Cited by 204 · see citing works

Obesity and COVID-19: what makes obese host so vulnerable?

Mohammad, S., Aziz, R., Mahri, S. A., Malik, S. S., Haji, E. M., Khan, A. H., Khatlani, T., & Bouchama, A. (2021) · Immunity & Ageing · doi:10.1186/s12979-020-00212-x · Cited by 180 · see citing works

Neutrophils and COVID-19: The road so far

Silva, L. H. A. C., Carvalho, D. C. M., Lima, É. D. A., Galvão, J. G. F. M., da Silva, J. S. D. F., de Sales-Neto, J. M., & Rodrigues‐Mascarenhas, S. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.107233 · Cited by 166 · see citing works

SARS‐CoV‐2 infection as a trigger of autoimmune response

Sacchi, M. C., Tamiazzo, S., Stobbione, P., Agatea, L., Gaspari, P. D., Stecca, A., Lauritano, E. C., Roveta, A., Tozzoli, R., Guaschino, R., et al. (2020) · Clinical and Translational Science · doi:10.1111/cts.12953 · Cited by 165 · see citing works

Sequelae, persistent symptomatology and outcomes after COVID-19 hospitalization: the ANCOHVID multicentre 6-month follow-up study

Romero-Duarte, Á., Rivera‐Izquierdo, M., de Alba, I. G.-F., Pérez-Contreras, M., Fernández‐Martínez, N. F., Ruiz-Montero, R., Serrano-Ortiz, Á., Ortiz-González-Serna, R., Salcedo-Leal, I., Jiménez-Mejías, E., et al. (2021) · BMC Medicine · doi:10.1186/s12916-021-02003-7 · Cited by 161 · see citing works

Potential sources, modes of transmission and effectiveness of prevention measures against SARS-CoV-2

Kampf, G., Brüggemann, Y., Kaba, H. E. J., Steinmann, J., Pfaender, S., Scheithauer, S., & Steinmann, E. (2020) · Journal of Hospital Infection · doi:10.1016/j.jhin.2020.09.022 · Cited by 139 · see citing works

T helper type (Th1/Th2) responses to SARS-CoV-2 and influenza A (H1N1) virus: From cytokines produced to immune responses

Aleebrahim‐Dehkordi, E., Molavi, B., Mokhtari, M., Deravi, N., Fathi, M., Fazel, T., Mohebalizadeh, M., Koochaki, P., Shobeiri, P., & Dehkordi, A. H. (2021) · Transplant Immunology · doi:10.1016/j.trim.2021.101495 · Cited by 129 · see citing works

Sex Disparities in COVID-19 Severity and Outcome: Are Men Weaker or Women Stronger?

Pivonello, R., Auriemma, R. S., Pivonello, C., Isidori, A. M., Corona, G., Colao, A. A. L., & Millar, R. P. (2020) · Neuroendocrinology · doi:10.1159/000513346 · Cited by 132 · see citing works

Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

Farahani, M., Niknam, Z., Amirabad, L. M., Dashatan, N. A., Koushki, M., Nemati, M., Pouya, F. D., Rezaei–Tavirani, M., Rasmi, Y., & Tayebi, L. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112420 · Cited by 125 · see citing works

Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials

Vegivinti, C. T. R., Evanson, K. W., Lyons, H., Akosman, I., Barrett, A., Hardy, N. J., Kane, B., Keesari, P. R., Pulakurthi, Y. S., Sheffels, E., et al. (2022) · BMC Infectious Diseases · doi:10.1186/s12879-022-07068-0 · Cited by 119 · see citing works

Heart-rate-variability (HRV), predicts outcomes in COVID-19

Mol, M. B. A., Strous, M. T. A., van Osch, F., Vogelaar, F. J., Barten, D. G., Farchi, M. U., Foudraine, N. A., & Gidron, Y. (2021) · PLoS ONE · doi:10.1371/journal.pone.0258841 · Cited by 118 · see citing works

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

Liu, G., Zhu, M., Zhao, X., & Nie, G. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113889 · Cited by 114 · see citing works

Weather Variability and COVID-19 Transmission: A Review of Recent Research

McClymont, H., & Hu, W. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18020396 · Cited by 113 · see citing works

Acute and post-acute phase of COVID-19: Analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC

Donyavi, T., Bokharaei‐Salim, F., Baghi, H. B., Khanaliha, K., JanatMakan, M. A., Karimi, B., Nahand, J. S., Mirzaei, H., Khatami, A., Garshasbi, S., et al. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107641 · Cited by 108 · see citing works

Role of platelet‐to‐lymphocyte count ratio (PLR), as a prognostic indicator in COVID‐19: A systematic review and meta‐analysis

Sarkar, S., Kannan, S., Khanna, P., & Singh, A. K. (2021) · Journal of Medical Virology · doi:10.1002/jmv.27297 · Cited by 110 · see citing works

The Inflammasome in Times of COVID-19

Vaccari, J. C. D. R., Dietrich, W. D., Keane, R. W., & Vaccari, J. P. D. R. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.583373 · Cited by 102 · see citing works

Calming the Storm: Natural Immunosuppressants as Adjuvants to Target the Cytokine Storm in COVID-19

Peter, A. E., Sandeep, B. V., Rao, B. G., & Kalpana, V. L. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.583777 · Cited by 99 · see citing works

Comprehensive Meta-Analysis of COVID-19 Global Metabolomics Datasets

Pang, Z., Zhou, G., Chong, J., & Xia, J. (2021) · Metabolites · doi:10.3390/metabo11010044 · Cited by 99 · see citing works

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection

Singh, K., Chen, Y., Hassanzadeh, S., Han, K., Judy, J., Seifuddin, F., Tunc, I., Sack, M. N., & Pirooznia, M. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.599261 · Cited by 94 · see citing works

Minor Clinical Impact of COVID-19 Pandemic on Patients With Primary Immunodeficiency in Israel

Marcus, N., Frizinsky, S., Hagin, D., Ovadia, A., Hanna, S., Farkash, M., Segal, R. M., Agmon‐Levin, N., Broides, A., Nahum, A., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.614086 · Cited by 95 · see citing works

MSCs vs. iPSCs: Potential in therapeutic applications

Thanaskody, K., Jusop, A. S., Tye, G. J., Zaman, W. S. W. K., Dass, S. A., & Nordin, F. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1005926 · Cited by 102 · see citing works

Identification of Parameters Representative of Immune Dysfunction in Patients with Severe and Fatal COVID-19 Infection: a Systematic Review and Meta-analysis

Qin, R., He, L., Yang, Z., Jia, N., Chen, R., Xie, J., Fu, W., Chen, H., Lin, X., Huang, R., et al. (2022) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-021-08908-8 · Cited by 93 · see citing works

Thermal and Magnetic Dual-Responsive Catheter-Assisted Shape Memory Microrobots for Multistage Vascular Embolization

Peng, Q., Wang, S., Han, J., Huang, C., Yu, H., Li, D., Qiu, M., Cheng, S., Wu, C., Cai, M., et al. (2024) · Research · doi:10.34133/research.0339 · Cited by 89 · see citing works

SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney

Francis, M. E., Goncin, U., Kroeker, A., Swan, C. L., Ralph, R., Lu, Y. W. W., Etzioni, A. L., Falzarano, D., Gerdts, V., Machtaler, S., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009705 · Cited by 89 · see citing works

Combining L-Arginine with vitamin C improves long-COVID symptoms: The LINCOLN Survey

Izzo, R., Trimarco, V., Mone, P., Aloè, T., Marzani, M. C., Diana, A., Fazio, G., Mallardo, M., Maniscalco, M., Marazzi, G., et al. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106360 · Cited by 89 · see citing works

β-Caryophyllene, A Natural Dietary CB2 Receptor Selective Cannabinoid can be a Candidate to Target the Trinity of Infection, Immunity, and Inflammation in COVID-19

Jha, N. K., Sharma, C., Hashiesh, H. M., Arunachalam, S., Meeran, M. F. N., Javed, H., Patil, C. R., Goyal, S. N., & Ojha, S. K. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.590201 · Cited by 86 · see citing works

A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19

Reinold, J., Farahpour, F., Fehring, C., Dolff, S., Konik, M., Korth, J., van Baal, L., Hoffmann, D. E., Buer, J., Witzke, O., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.747816 · Cited by 84 · see citing works

Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection

Severa, M., Diotti, R. A., Etna, M. P., Rizzo, F., Fiore, S., Ricci, D., Iannetta, M., Sinigaglia, A., Lodi, A., Mancini, N., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009878 · Cited by 85 · see citing works

Long non-coding RNAs (lncRNAs) NEAT1 and MALAT1 are differentially expressed in severe COVID-19 patients: An integrated single-cell analysis

Kai, H., Wang, C., Vagts, C. L., Raguveer, V., Finn, P. W., & Perkins, D. L. (2022) · PLoS ONE · doi:10.1371/journal.pone.0261242 · Cited by 85 · see citing works

Effects of adding L-arginine orally to standard therapy in patients with COVID-19: A randomized, double-blind, placebo-controlled, parallel-group trial. Results of the first interim analysis

Fiorentino, G., Coppola, A., Izzo, R., Annunziata, A., Bernardo, M., Lombardi, A., Trimarco, V., Santulli, G., & Trimarco, B. (2021) · EClinicalMedicine · doi:10.1016/j.eclinm.2021.101125 · Cited by 85 · see citing works

Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis

Ansone, L., Brīvība, M., Silamiķelis, I., Terentjeva, A., Pērkons, I., Birzniece, L., Rovīte, V., Rozentāle, B., Vīksna, L., Koļesova, O., et al. (2021) · Microbiology Spectrum · doi:10.1128/spectrum.00338-21 · Cited by 81 · see citing works

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Ning, Q., Wu, D., Wang, X., Xi, D., Chen, T., Chen, G., Wang, H., Lü, H., Wang, M., Zhu, L., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00907-1 · Cited by 82 · see citing works

Immunogenic and reactogenic efficacy of Covaxin and Covishield: a comparative review

Das, S., Kar, S. S., Samanta, S., Banerjee, J., Giri, B., & Dash, S. K. (2022) · Immunologic Research · doi:10.1007/s12026-022-09265-0 · Cited by 81 · see citing works

Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?

Verkhratsky, A., Li, Q., Melino, S., Melino, G., & Shi, Y. (2020) · Biology Direct · doi:10.1186/s13062-020-00282-3 · Cited by 78 · see citing works

Serum ferritin at admission in hospitalized COVID-19 patients as a predictor of mortality

Lino, K., Guimarães, G. M. C., Alves, L. S., Oliveira, A. C., Faustino, R. D. S., Souza, C. F., Tupinambá, G., Medeiros, T., Silva, A. A., & Almeida, J. R. (2021) · The Brazilian Journal of Infectious Diseases · doi:10.1016/j.bjid.2021.101569 · Cited by 79 · see citing works

Catecholamine physiology and its implications in patients with COVID-19

Gubbi, S., Nazari, M. A., Taïeb, D., Kłubo-Gwieździńska, J., & Pacák, K. (2020) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(20)30342-9 · Cited by 73 · see citing works

Severe COVID-19 and Sepsis: Immune Pathogenesis and Laboratory Markers

Zafer, M. M., El‐Mahallawy, H. A., & Ashour, H. M. (2021) · Microorganisms · doi:10.3390/microorganisms9010159 · Cited by 73 · see citing works

Glutathione Supplementation as an Adjunctive Therapy in COVID-19

Guloyan, V., Oganesian, B., Baghdasaryan, N., Yeh, C., Singh, M., Guilford, F. T., Ting, Y.-S., & Venketaraman, V. (2020) · Antioxidants · doi:10.3390/antiox9100914 · Cited by 73 · see citing works

Transient monoarthritis and psoriatic skin lesions following COVID-19

Stefano, L. D., Rossi, S., Montecucco, C., & Bugatti, S. (2020) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2020-218520 · Cited by 69 · see citing works

Midterm functional sequelae and implications in rehabilitation after COVID-19: a cross-sectional study

Baricich, A., No-more Covid Group, Borg, M. B., Cuneo, D., CADARIO, E., Azzolina, D., Balbo, P. E., Bellan, M., Zeppegno, P., Pirisi, M., et al. (2021) · European Journal of Physical and Rehabilitation Medicine · doi:10.23736/s1973-9087.21.06699-5 · Cited by 69 · see citing works

Natural Killer Cells in SARS-CoV-2 Infection: Pathophysiology and Therapeutic Implications

Vito, C. D., Calcaterra, F., Coianiz, N., Terzoli, S., Voza, A., Mikulak, J., Bella, S. D., & Mavilio, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.888248 · Cited by 69 · see citing works

High‐dose methylprednisolone in nonintubated patients with severe COVID‐19 pneumonia

Papamanoli, A., Yoo, J., Grewal, P. K., Predun, W., Hotelling, J., Jacob, R., Mojahedi, A., Skopicki, H. A., Mansour, M., Marcos, L. A., et al. (2020) · European Journal of Clinical Investigation · doi:10.1111/eci.13458 · Cited by 69 · see citing works

Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity

Torres-Ruiz, J. J., Absalón‐Aguilar, A., Nuñez‐Aguirre, M., Pérez‐Fragoso, A., Carrillo-Vázquez, D. A., Maravillas‐Montero, J. L., Mejía‐Domínguez, N. R., Llorente, L., Alcalá‐Carmona, B., Lira‐Luna, J., et al. (2021) · Cells · doi:10.3390/cells10102545 · Cited by 68 · see citing works

Pulling-Force Spinning Top for Serum Separation Combined with Paper-Based Microfluidic Devices in COVID-19 ELISA Diagnosis

Gong, F., Wei, H.-X., Qi, J., Ma, H., Liu, L., Weng, J., Zheng, X., Li, Q., Zhao, D., Fang, H., et al. (2021) · ACS Sensors · doi:10.1021/acssensors.1c00773 · Cited by 67 · see citing works

Alterations in the respiratory tract microbiome in COVID-19: current observations and potential significance

Merenstein, C., Bushman, F. D., & Collman, R. G. (2022) · Microbiome · doi:10.1186/s40168-022-01342-8 · Cited by 67 · see citing works

Nitazoxanide superiority to placebo to treat moderate COVID-19 – A Pilot prove of concept randomized double-blind clinical trial.

Blum, V. F., Cimerman, S., Hunter, J., Tierno, P. F. G. M. M., Lacerda, A. L. T., Soeiro, A. D. M., Cardoso, F., Bellei, N., Maricato, J. T., Mantovani, N., et al. (2021) · EClinicalMedicine · doi:10.1016/j.eclinm.2021.100981 · Cited by 66 · see citing works

COVID-19 and Systemic Lupus Erythematosus: Focus on Immune Response and Therapeutics

Spihlman, A. P., Gadi, N., Wu, S., & Moulton, V. R. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.589474 · Cited by 65 · see citing works

A novel platform for attenuating immune hyperactivity using EXO‐CD24 in COVID‐19 and beyond

Shapira, S., Shimon, M. B., Hay-Levy, M., Shenberg, G., Choshen, G., Bannon, L., Tepper, M., Kazanov, D., Seni, J., Lev‐Ari, S., et al. (2022) · EMBO Molecular Medicine · doi:10.15252/emmm.202215997 · Cited by 64 · see citing works

A pilot study on intravenous N-Acetylcysteine treatment in patients with mild-to-moderate COVID19-associated acute respiratory distress syndrome

Taher, A., Lashgari, M., Sedighi, L., Rahimi‐Bashar, F., Poorolajal, J., & Mehrpooya, M. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00296-2 · Cited by 63 · see citing works

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Pinheiro, T., Cardoso, A. R. A., Sousa, C. E. A., Marques, A. C., Tavares, A. P. M., Matos, A. M., Cruz, M. T., Moreira, F. T. C., Martins, R., Fortunato, E. M. C., et al. (2021) · ACS Omega · doi:10.1021/acsomega.1c04012 · Cited by 62 · see citing works

Kynurenine serves as useful biomarker in acute, Long- and Post-COVID-19 diagnostics

Bizjak, D. A., Stangl, M. J., Börner, N., Bösch, F., Durner, J., Drunin, G., Buhl, J. L., & Abendroth, D. K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1004545 · Cited by 61 · see citing works

IL-6 and IL-10 are associated with disease severity and higher comorbidity in adults with COVID-19

Luporini, R. L., Rodolpho, J. M. D. A., Kubota, L. T., Martin, A. C. B. M., Cominetti, M. R., Aníbal, F. D. F., & Pott, H. (2021) · Cytokine · doi:10.1016/j.cyto.2021.155507 · Cited by 59 · see citing works

Role of red blood cell distribution width, as a prognostic indicator in COVID‐19: A systematic review and meta‐analysis

Sarkar, S., Kannan, S., Khanna, P., & Singh, A. K. (2021) · Reviews in Medical Virology · doi:10.1002/rmv.2264 · Cited by 58 · see citing works

T-Cell Receptor Repertoire Sequencing and Its Applications: Focus on Infectious Diseases and Cancer

Mazzotti, L., Gaimari, A., Bravaccini, S., Maltoni, R., Cerchione, C., Juan, M., González‐Navarro, E. A., Pasetto, A., Silva, D. N., Ancarani, V., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158590 · Cited by 61 · see citing works

High-Dose Intravenous Immunoglobulin in Severe Coronavirus Disease 2019: A Multicenter Retrospective Study in China

Cao, W., Liu, X., Hong, K., Ma, Z., Zhang, Y., Lin, L., Han, Y., Xiong, Y., Liu, Z., Ruan, L., et al. (2020) · Frontiers in Immunology · doi:10.2139/ssrn.3696870 · Cited by 57 · see citing works

Biosurfactants’ Potential Role in Combating COVID-19 and Similar Future Microbial Threats

Çelik, P. A., Enuh, B. M., Çabuk, A., & Banat, I. M. (2020) · Applied Sciences · doi:10.3390/app11010334 · Cited by 56 · see citing works

Pathogenesis‐directed therapy of 2019 novel coronavirus disease

Stratton, C. W., Tang, Y., & Lu, H. (2020) · Journal of Medical Virology · doi:10.1002/jmv.26610 · Cited by 55 · see citing works

A possible pathogenic role of Syndecan-1 in the pathogenesis of coronavirus disease 2019 (COVID-19)

Karampoor, S., Zahednasab, H., Farahmand, M., Mirzaei, R., Zamani, F., Tabibzadeh, A., Bouzari, B., Ajdarkosh, H., Nikkhah, M., Hashemi, M. R., et al. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107684 · Cited by 54 · see citing works

Arginase 1 (Arg1) as an Up-Regulated Gene in COVID-19 Patients: A Promising Marker in COVID-19 Immunopathy

Derakhshani, A., Hemmat, N., Asadzadeh, Z., Ghaseminia, M., Shadbad, M. A., Jadideslam, G., Silvestris, N., Racanelli, V., & Baradaran, B. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10051051 · Cited by 52 · see citing works

Coronavirus Disease 2019 (COVID-19) in a Patient with Disseminated Histoplasmosis and HIV—A Case Report from Argentina and Literature Review

Messina, F. A., Marín, E., Caceres, D. H., Romero, M., Depardo, R., Priarone, M. M., Rey, L., Vázquez, M., Verweij, P. E., Chiller, T. M., et al. (2020) · Journal of Fungi · doi:10.3390/jof6040275 · Cited by 54 · see citing works

Use of vitamin/zinc supplements, medicinal plants, and immune boosting drinks during COVID-19 pandemic: A pilot study from Benha city, Egypt

Khabour, O. F., & Hassanein, S. F. M. (2021) · Heliyon · doi:10.1016/j.heliyon.2021.e06538 · Cited by 57 · see citing works

Muscle dysfunction in the long coronavirus disease 2019 syndrome: Pathogenesis and clinical approach

Silva, C. C., Bichara, C. N. C., Carneiro, F. R. O., Palácios, V. R. D. C. M., van den Berg, A. V. S., Quaresma, J. A. S., & Falcão, L. F. M. (2022) · Reviews in Medical Virology · doi:10.1002/rmv.2355 · Cited by 62 · see citing works

MicroRNAs and SARS-CoV-2 life cycle, pathogenesis, and mutations: biomarkers or therapeutic agents?

Abedi, F., Rezaee, R., Hayes, A. W., Nasiripour, S., & Karimi, G. (2020) · Cell Cycle · doi:10.1080/15384101.2020.1867792 · Cited by 51 · see citing works

Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors

Mor, M., Werbner, M., Alter, J., Safra, M., Chomsky, E., Lee, J. C., Hada-Neeman, S., Polonsky, K., Nowell, C., Clark, A., et al. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009165 · Cited by 47 · see citing works

A comprehensive review about immune responses and exhaustion during coronavirus disease (COVID-19)

Mohammed, R. N., Tamjidifar, R., Rahman, H. S., Adili, A., Ghoreishizadeh, S., Saeedi, H., Thangavelu, L. P., Shomali, N., Aslaminabad, R., Marofi, F., et al. (2022) · Cell Communication and Signaling · doi:10.1186/s12964-022-00856-w · Cited by 53 · see citing works

Circulating Type I Interferon Levels and COVID-19 Severity: A Systematic Review and Meta-Analysis

da Silva, R. P., Gonçalves, J. I. B., Zanin, R. F., Schuch, F. B., & de Souza, A. P. D. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.657363 · Cited by 50 · see citing works

Case Report: Hyperbilirubinemia in Gilbert Syndrome Attenuates Covid-19-Induced Metabolic Disturbances

Al-Kuraishy, H. M., Al-Gareeb, A. I., Abdullah, S. M., Martins, N. A., & Batiha, G. E. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.642181 · Cited by 52 · see citing works

Calming the cytokine storm of COVID-19 through inhibition of JAK2/STAT3 signaling

Gajjela, B. K., & Zhou, M. (2021) · Drug Discovery Today · doi:10.1016/j.drudis.2021.10.016 · Cited by 52 · see citing works

Epigenetic Landscapes of Single-Cell Chromatin Accessibility and Transcriptomic Immune Profiles of T Cells in COVID-19 Patients

Li, S., Wu, B., Ling, Y., Guo, M., Qin, B., Ren, X., Wang, C., Yang, H., Chen, L., Liao, Y., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.625881 · Cited by 51 · see citing works

Wearable technology for early detection of COVID-19: A systematic scoping review

Cheong, S. H. R., Ng, Y. J. X., Lau, Y., & Lau, S. T. (2022) · Preventive Medicine · doi:10.1016/j.ypmed.2022.107170 · Cited by 49 · see citing works

Targeting the SphK-S1P-SIPR Pathway as a Potential Therapeutic Approach for COVID-19

McGowan, E. M., Haddadi, N., Nassif, N. T., & Lin, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197189 · Cited by 50 · see citing works

The immune response and immune evasion characteristics in SARS-CoV, MERS-CoV, and SARS-CoV-2: Vaccine design strategies

Molaei, S., Dadkhah, M., Asghariazar, V., Karami, C., & Safarzadeh, E. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.107051 · Cited by 49 · see citing works

SARS-CoV-2 Infection and Oral Health: Therapeutic Opportunities and Challenges

Coke, C. J., Davison, B., Fields, N., Fletcher, J., Rollings, J., Roberson, L., Challagundla, K. B., Sampath, C., Cade, J., Farmer‐Dixon, C. M., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10010156 · Cited by 50 · see citing works

Modifiable lifestyle factors and severe COVID-19 risk: a Mendelian randomisation study

Li, S., & Hua, X. (2021) · BMC Medical Genomics · doi:10.1186/s12920-021-00887-1 · Cited by 50 · see citing works

Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment

Valdez-Cruz, N. A., García-Hernández, E., Espitia, C., Cobos-Marín, L., Altamirano, C., Bando-Campos, C. G., Cofas-Vargas, L. F., Coronado-Aceves, E. W., González-Hernández, R. A., Hernández-Peralta, P., et al. (2021) · Microbial Cell Factories · doi:10.1186/s12934-021-01576-5 · Cited by 45 · see citing works

Comorbidities and clinical complications associated with SARS-CoV-2 infection: an overview

Gupta, A., Marzook, H., & Ahmad, F. (2022) · Clinical and Experimental Medicine · doi:10.1007/s10238-022-00821-4 · Cited by 49 · see citing works

ACTIVating Resources for the COVID-19 Pandemic: In Vivo Models for Vaccines and Therapeutics

Hewitt, J. A., Lutz, C., Florence, W. C., Pitt, M. L., Rao, S., Rappaport, J., & Haigwood, N. (2020) · Cell Host and Microbe · doi:10.1016/j.chom.2020.09.016 · Cited by 47 · see citing works

Presentation and management of anxiety in individuals with acute symptomatic or asymptomatic COVID-19 infection, and in the post-COVID-19 recovery phase

Uzunova, G., Pallanti, S., & Hollander, E. (2021) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651501.2021.1887264 · Cited by 49 · see citing works

Thyroid disease and hypothyroidism are associated with poor COVID-19 outcomes: A systematic review, meta-analysis, and meta-regression

Damara, F. A., Muchamad, G. R., Ikhsani, R., Hendro, H., Syafiyah, A. H., & Bashari, M. H. (2021) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2021.102312 · Cited by 48 · see citing works

COVID-19 in Immunosuppressed Children

Nicastro, E., Verdoni, L., Bettini, L. R., Zuin, G., Balduzzi, A., Montini, G., Biondi, A., & D’Antiga, L. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.629240 · Cited by 48 · see citing works

A systematic review and meta-analysis of the association between the neutrophil, lymphocyte, and platelet count, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio and COVID-19 progression and mortality

Zinellu, A., & Mangoni, A. A. (2022) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2022.2120472 · Cited by 47 · see citing works

Antibody landscape against SARS-CoV-2 reveals significant differences between non-structural/accessory and structural proteins

Li, Y., Xu, Z., Lei, Q., Lai, D., Hou, H., Jiang, H., Zheng, Y.-X., Wang, X., Wu, J., Ma, M., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109391 · Cited by 46 · see citing works

SARS CoV-2 Organotropism Associated Pathogenic Relationship of Gut-Brain Axis and Illness

Shinu, P., Morsy, M. A., Deb, P. K., Nair, A. B., Goyal, M., Jigar, S., & Kotta, S. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.606779 · Cited by 45 · see citing works

Functional food: complementary to fight against COVID-19

Farzana, M., Shahriar, S., Jeba, F. R., Tabassum, T., Araf, Y., Ullah, M. A., Tasnim, J., Chakraborty, A., Naima, T. A., Marma, K. K. S., et al. (2022) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-022-00217-z · Cited by 45 · see citing works

Synergistic Anti-Inflammatory Activity of Ginger and Turmeric Extracts in Inhibiting Lipopolysaccharide and Interferon-γ-Induced Proinflammatory Mediators

Zhou, X., Afzal, S., Wohlmuth, H., Münch, G. W., Leach, D. N., Low, M., & Li, C. G. (2022) · Molecules · doi:10.3390/molecules27123877 · Cited by 45 · see citing works

Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathways

Amini‐Farsani, Z., Yadollahi‐Farsani, M., Arab, S., Forouzanfar, F., Yadollahi, M., & Asgharzade, S. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.108071 · Cited by 45 · see citing works

Corrigendum: High-Dose Intravenous Immunoglobulin in Severe Coronavirus Disease 2019: A Multicenter Retrospective Study in China

Cao, W., Liu, X., Hong, K., Ma, Z., Zhang, Y., Lin, L., Han, Y., Xiong, Y., Liu, Z., Ruan, L., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.671443 · Cited by 44 · see citing works

Longitudinal Plasma Proteomics Analysis Reveals Novel Candidate Biomarkers in Acute COVID-19

Mohammed, Y., Goodlett, D. R., Cheng, M. P., Vinh, D. C., Lee, T. C., McGeer, A., Sweet, D. D., Tran, K. C., Lee, T., Murthy, S., et al. (2022) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00863 · Cited by 41 · see citing works

Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential Pathogenesis

McGrowder, D. A., Miller, F. G., Cross, M. A., Anderson-Jackson, L., Bryan, S., & Dilworth, L. (2021) · Diseases · doi:10.3390/diseases9030050 · Cited by 40 · see citing works

A review on the immune responses against novel emerging coronavirus (SARS-CoV-2)

Lotfi, R., Kalmarzi, R. N., & Roghani, S. A. (2021) · Immunologic Research · doi:10.1007/s12026-021-09198-0 · Cited by 33 · see citing works

A review of the effect of COVID-19 on immune responses of the body

Hekmatnia, Y., Rahmani, F., Feili, Z., & Ebrahimzadeh, F. (2022) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_677_21 · Cited by 12 · see citing works

The trinity of COVID-19: immunity, inflammation and intervention

Tay, M. Z., Poh, C. M., Rénia, L., MacAry, P. A., & Ng, L. F. P. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0311-8 · Cited by 4,360 · see citing works

COVID-19: Inflammatory Profile

Wang, Y., & Perlman, S. M. (2021) · Annual Review of Medicine · doi:10.1146/annurev-med-042220-012417 · Cited by 89 · see citing works

Mechanistic insight into the protective and pathogenic immune-responses against SARS-CoV-2

Purbey, P. K., Roy, K., Gupta, S., & Paul, M. K. (2023) · Molecular Immunology · doi:10.1016/j.molimm.2023.03.009 · Cited by 18 · see citing works