The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
Open accessAbstract
Calreticulin-induced phagocytosis of cancer cells can be counterbalanced by CD47 expression.
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“increased CD47 levels on the surface of malignant cells correlate with dismal prognosis in subjects with AML, esophageal carcinoma, and ovarian cancer [888–891].”
From Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018. (2018) · cites this paper as [890]
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Calreticulin exposure dictates the immunogenicity of cancer cell death
Obeid, M., Tesniere, A., Ghiringhelli, F., Fimia, G. M., Apetoh, L., Perfettini, J.-L., Castedo, M., Mignot, G., Panaretakis, T., Casares, N., et al. (2007) · Nature Medicine · doi:10.1038/nm1523 · Cited by 3,216
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
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Self-citationCD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis
Jaiswal, S., Jamieson, C. H. M., Pang, W. W., Park, C. Y., Chao, M. P., Majeti, R., Traver, D. J., van Rooijen, N., & Weissman, I. L. (2009) · Cell · doi:10.1016/j.cell.2009.05.046 · Cited by 1,578
Self-citationA blast from the past: clearance of apoptotic cells regulates immune responses
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Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680
Immunogenic Cell Death in Cancer Therapy
Kroemer, G., Galluzzi, L., Kepp, O., & Zitvogel, L. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-100008 · Cited by 3,303
Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
Nangalia, J., Massie, C. E., Baxter, E. J., Nice, F. L., Gundem, G., Wedge, D. C., Avezov, E., Li, J., Kollmann, K., Kent, D. G., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1312542 · Cited by 1,756
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Self-citationAutophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
Michaud, M., Martins, I., Sukkurwala, A. Q., Adjemian, S., Ma, Y., Pellegatti, P., Shen, S., Kepp, O., Scoazec, M., Mignot, G., et al. (2011) · Science · doi:10.1126/science.1208347 · Cited by 1,377
Metadata
- Authors
- Chao, M. P., Jaiswal, S., Weissman-Tsukamoto, R., Alizadeh, A. A., Gentles, A. J., Volkmer, J., Weiskopf, K., Willingham, S. B., Raveh, T., Park, C. Y., Majeti, R., & Weissman, I. L.
- Affiliations
- Institute for Stem Cell Biology and Regenerative Medicine (US)
- Massachusetts General Hospital (US)
- Stanford Medicine (US)
- Stanford University (US)
- Memorial Sloan Kettering Cancer Center (US)
- Corresponding author
- Chao, Mark P.
- Majeti, Ravindra
- Weissman, Irving L.
- ORCID
- Venue
- Science Translational Medicine
- Published
- 2010-12-22
- Volume
- 2
- Issue
- 63
- Pages
- 63ra94-63ra94
- ISSN
- 1946-6234 (ISSN-L)
- 1946-6242
- PMC
- PMC4126904
- OpenAlex
- W2142541925
- Cited by
- 776
- References
- 55
- Citations by year
- 2026: 35 · 2025: 51 · 2024: 62 · 2023: 81 · 2022: 76 · 2021: 72 · 2020: 62 · 2019: 54 · 2018: 40 · 2017: 48 · 2016: 36 · 2015: 49 · 2014: 31 · 2013: 28 · 2012: 36
- FWCI
- 10.73
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science Translational Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Cancer Institute (U54CA149145, CA09302, P01CA139490, R01CA086017, T32CA009302)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Keywords
- calreticulin, CD47, anti-CD47 antibody, low density lipoprotein receptor-related protein, tumor immune evasion, prognostic factors, acute myeloid leukemia, non-Hodgkin lymphoma, bladder cancer, neuroblastoma, innate immunity
- MeSH terms
- Animals, Urinary Bladder Neoplasms, Cell Line, Flow Cytometry, Humans, Lymphoma, Non-Hodgkin, Phagocytosis, Leukemia, Myeloid, Acute, Calreticulin, Cell Line, Tumor, Mice, CD47 Antigen, In Vitro Techniques
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