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Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers

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Kim, Jungsun, Bamlet, William R., Oberg, Ann L., Chaffee, Kari G., Donahue, Greg, Cao, Xing-Jun, Chari, Suresh, Garcia, Benjamin A., Petersen, Gloria M., Zaret, Kenneth S.·2017·Science Translational Medicine

DOI 10.1126/scitranslmed.aah5583PMC PMC5727893

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THBS2 and CA19-9 markers in human blood improve detection of pancreatic ductal adenocarcinoma.

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Authors: Kim, J., Bamlet, W. R., Oberg, A. L., Chaffee, K. G., Donahue, G., Cao, X.-J., Chari, S., Garcia, B. A., Petersen, G. M., & Zaret, K. S.
Affiliations: Abramson Cancer Center (US)
Mayo Clinic (US)
Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
University of Pennsylvania (US)
Corresponding author: Zaret, Kenneth S.
ORCID: Kim, Jungsun
Bamlet, William R.
Oberg, Ann L.
Chaffee, Kari G.
Donahue, Greg
Cao, Xing-Jun
Chari, Suresh
Garcia, Benjamin A.
Petersen, Gloria M.
Zaret, Kenneth S.
Venue: Science Translational Medicine
Publisher: American Association for the Advancement of Science (AAAS)
Published: 2017-07-12
Volume: 9
Issue: 398
ISSN: 1946-6234 (ISSN-L)
1946-6242
DOI: 10.1126/scitranslmed.aah5583
PMC: PMC5727893
OpenAlex: W2734646423
Cited by: 269
References: 57
Citations by year: 2026: 18 · 2025: 17 · 2024: 24 · 2023: 22 · 2022: 39 · 2021: 52 · 2020: 39 · 2019: 23 · 2018: 29 · 2017: 6
FWCI: 11.70
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Science Translational Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Department of Defense (award308650, BC123187P1)
NIH Office of the Director (award307521, DK108288-02, award308646, R01GM36477, award308647, P30DK050306, award308649, P50CA102701, award308648, R01CA208517, award308651, P30DK19525)
Topics: Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
Health Sciences › Medicine › Surgery › Cholangiocarcinoma and Gallbladder Cancer Studies
Keywords: pancreatic ductal adenocarcinoma, thrombospondin-2, CA19-9, early cancer detection, plasma biomarkers, tumor staging
MeSH terms: Thrombospondin 2, Adenocarcinoma, Aged, Demography, Female, Humans, Male, Middle Aged, Biomarkers, Tumor, Reproducibility of Results, Case-Control Studies, CA-19-9 Antigen, Thrombospondins, Carcinoma, Pancreatic Ductal, Early Detection of Cancer

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Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers

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