Cited by 148Antifungal resistance and susceptibilityFungal Plant Pathogen ControlYeasts and Rust Fungi Studies

Emergence of a Candida krusei Isolate with Reduced Susceptibility to Caspofungin during Therapy

Open access
Hakki, Morgan, Staab, Janet F., Marr, Kieren A.·2006·Antimicrobial Agents and Chemotherapy

Abstract

Clinical failure associated with reduced susceptibility to caspofungin has been described in Candida albicans and C. parapsilosis . We report a case of Candida krusei infection that progressed despite caspofungin therapy. Reduced microbial susceptibility to all three echinocandins (caspofungin, anidulafungin, and micafungin) was noted but was not associated with mutations in FKS1 .

Integrity signals

Registry

Crossref · 10.1128/aac.00148-06

Cites

10 of 10 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Hakki, M., Staab, J. F., & Marr, K. A.
Affiliations
  • University of Washington (US)
  • Fred Hutch Cancer Center (US)
Corresponding author
Marr, Kieren A.
Venue
Antimicrobial Agents and Chemotherapy
Published
2006-07
Volume
50
Issue
7
Pages
2522-2524
ISSN
  • 0066-4804 (ISSN-L)
  • 1098-6596
OpenAlex
W2109890308
Cited by
148
References
10
Citations by year
2025: 2 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 2 · 2020: 4 · 2019: 4 · 2018: 4 · 2017: 4 · 2016: 2 · 2015: 7 · 2014: 11 · 2013: 5 · 2012: 9
FWCI
13.36
Type
journal article
Language
en
Open access
Locations
  • Antimicrobial Agents and Chemotherapy (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Fungal Plant Pathogen Control
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
Keywords
Candida krusei, caspofungin, reduced susceptibility, echinocandin resistance, anidulafungin, micafungin, FKS1, antifungal treatment failure, fungal infection
MeSH terms
Caspofungin, Adult, Antifungal Agents, Candida, Candidiasis, Oral, Female, Humans, Microbial Sensitivity Tests, Endophthalmitis, Peptides, Cyclic, Fungemia, Drug Resistance, Fungal, Echinocandins, Lipopeptides

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review