A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

Semenza, G L, Wang, G L·1992·Molecular and Cellular Biology

Cited by (134)

Items 101–134 of 134

  1. Ancient Atmospheres and the Evolution of Oxygen Sensing Via the Hypoxia-Inducible Factor in Metazoans
    Taylor, Cormac T., McElwain, Jennifer C. · 2010 · Physiology
  2. Maintenance of redox homeostasis by hypoxia-inducible factors
    Samanta, Debangshu, Semenza, Gregg L. · 2017 · Redox Biology
  3. Decreased Adipose Tissue Oxygenation Associates with Insulin Resistance in Individuals with Obesity
    Cifarelli, Vincenza, Beeman, Scott C., Smith, Gordon I., Yoshino, Jun, Morozov, Darya, Beals, Joseph W., Kayser, Brandon D., Watrous, Jeramie D., Jain, Mohit, Patterson, Bruce W. et al. · 2020 · Journal of Clinical Investigation
  4. Hypoxia and the phenomenon of immune exclusion
    Pietrobon, Violena, Marincola, Francesco M. · 2021 · Journal of Translational Medicine
  5. Hypoxia: Adapting to High Altitude by Mutating EPAS-1 , the Gene Encoding HIF-2α
    Tissot van Patot, Martha C., Gassmann, Max · 2011 · High Altitude Medicine & Biology
  6. The use of dioxygen by HIF prolyl hydroxylase (PHD1)
    McNeill, Luke A, Hewitson, Kirsty S, Gleadle, Jonathan M, Horsfall, Louise E, Oldham, Neil J, Maxwell, Patrick H, Pugh, Christopher W, Ratcliffe, Peter J, Schofield, Christopher J · 2002 · Bioorganic & Medicinal Chemistry Letters
  7. A Nontranscriptional Role for HIF-1α as a Direct Inhibitor of DNA Replication
    Hubbi, Maimon E., Kshitiz, Gilkes, Daniele M., Rey, Sergio, Wong, Carmen C., Luo, Weibo, Kim, Deok-Ho, Dang, Chi V., Levchenko, Andre, Semenza, Gregg L. · 2013 · Science Signaling
  8. Targeting hypoxic tumour cells to overcome metastasis
    Bennewith, Kevin L, Dedhar, Shoukat · 2011 · BMC Cancer
  9. Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration
    Köhler, Theresa, Reizis, Boris, Johnson, Randall S., Weighardt, Heike, Förster, Irmgard · 2012 · European Journal of Immunology
  10. Role of Ceruloplasmin in Macrophage Iron Efflux during Hypoxia
    Sarkar, Joydeep, Seshadri, Vasudevan, Tripoulas, Nicholas A., Ketterer, Michael E., Fox, Paul L. · 2003 · Journal of Biological Chemistry
  11. Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips
    Hagen, Thilo · 2012 · Biochemistry Research International
  12. Implication of the hypoxia response element of the Vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development
    Vinores, Stanley A., Xiao, Wei‐Hong, Aslam, Sadia, Shen, Jikui, Oshima, Yuji, Nambu, Hiroyuki, Liu, Hansheng, Carmeliet, Peter, Campochiaro, Peter A. · 2006 · Journal of Cellular Physiology
  13. Chromatin and oxygen sensing in the context of JmjC histone demethylases
    Shmakova, Alena, Batie, Michael, Druker, Jimena, Rocha, Sonia · 2014 · Biochemical Journal
  14. Oxygen‐sensing mechanisms in cells
    Wilson, James W., Shakir, Dilem, Batie, Michael, Frost, Mark, Rocha, Sonia · 2020 · The FEBS Journal
  15. Targeting HIF-2α in the Tumor Microenvironment: Redefining the Role of HIF-2α for Solid Cancer Therapy
    Davis, Leah, Recktenwald, Matthias, Hutt, Evan, Fuller, Schuyler, Briggs, Madison, Goel, Arnav, Daringer, Nichole · 2022 · Cancers
  16. Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor
    Barrett, Terrance D., Palomino, Heather L., Brondstetter, Theresa I., Kanelakis, Kimon C., Wu, Xiaodong, Haug, Peter V., Yan, Wen, Young, Andrew, Hua, Hong, Hart, Juliet C. et al. · 2011 · Molecular Pharmacology
  17. Hypoxia-inducible factors as key regulators of tumor inflammation
    Mamlouk, Soulafa, Wielockx, Ben · 2013 · International Journal of Cancer
  18. Regulation of ferrochelatase gene expression by hypoxia
    Liu, Yunying L., Ang, Sonny O., Weigent, Douglas A., Prchal, Josef T., Bloomer, Joseph R. · 2004 · Life Sciences
  19. Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia
    Fähling, M. · 2009 · Acta Physiologica
  20. HIF-1α influences myeloid cell antigen presentation and response to subcutaneous OVA vaccination
    Bhandari, Tamara, Olson, Joshua, Johnson, Randall S., Nizet, Victor · 2013 · Journal of Molecular Medicine
  21. Vascular growth factors in neuropsychiatry
    Newton, Samuel S., Fournier, Neil M., Duman, Ronald S. · 2013 · Cellular and Molecular Life Sciences
  22. Crosstalk between nitric oxide and hypoxia-inducible factor signaling pathways: an update
    Poyton, Robert, Hendrickson, Marina · 2015 · Research and Reports in Biochemistry
  23. The Role of the Hypoxia-Related Unfolded Protein Response (UPR) in the Tumor Microenvironment
    Bartoszewska, Sylwia, Collawn, James F., Bartoszewski, Rafal · 2022 · Cancers
  24. Hypoxia-inducible factor 2α: a novel target in gliomas
    Renfrow, Jaclyn J, Soike, Michael H, Debinski, Waldemar, Ramkissoon, Shakti H, Mott, Ryan T, Frenkel, Mark B, Sarkaria, Jann N, Lesser, Glenn J, Strowd, Roy E · 2018 · Future Medicinal Chemistry
  25. Multifaceted Interplay between Hormones, Growth Factors and Hypoxia in the Tumor Microenvironment
    Lappano, Rosamaria, Todd, Lauren A., Stanic, Mia, Cai, Qi, Maggiolini, Marcello, Marincola, Francesco, Pietrobon, Violena · 2022 · Cancers
  26. Erythropoietin signaling in peripheral macrophages is required for systemic β‐amyloid clearance
    Xu, Lu, Li, Lei, Pan, Cai‐Long, Song, Jing‐Jing, Zhang, Chen‐Yang, Wu, Xiang‐Hui, Hu, Fan, Liu, Xue, Zhang, Zhiren, Zhang, Zhi‐Yuan · 2022 · The EMBO Journal
  27. Hypoxia-inducible factor: roles in development, physiology, and disease
    Chandel, N S, Simon, M C · 2008 · Cell Death & Differentiation
  28. Regulation of the HIF switch in human endothelial and cancer cells
    Slawski, Jakub, Jaśkiewicz, Maciej, Barton, Anna, Kozioł, Sylwia, Collawn, James F., Bartoszewski, Rafał · 2024 · European Journal of Cell Biology
  29. Specific inhibition of HIF activity: can peptides lead the way?
    Mylonis, Ilias, Chachami, Georgia, Simos, George · 2021 · Cancers
  30. Developmental effects related to angiogenesis and osteogenic differentiation in Salmon larvae continuously exposed to dioxin-like 3,3′,4,4′-tetrachlorobiphenyl (congener 77)
    Olufsen, Marianne, Arukwe, Augustine · 2011 · Aquatic Toxicology
  31. HIF1α is not a target of 14q deletion in clear cell renal cancer
    Shenoy, Niraj · 2020 · Scientific Reports
  32. Hypoxia Sensing in Resident Cardiac Macrophages Regulates the Arg1 Macrophage Lineage During Ischemic Heart Injury
    Kadyrov, Farid F., Koenig, Andrew L., Amrute, Junedh M., Dun, Hao, Li, Wenjun, Weinheimer, Carla J., Nigro, Jessica M., Kovacs, Attila, Bredemeyer, Andrea L., Lai, Lulu et al. · 2022
  33. HIF inhibition: Current strategies and clinical challenges
    Więch-Walów, Anna, Bartoszewska, Sylwia, Barton, Anna, Czechowicz, Paulina, Dudzik, Jakub, Wielockx, Ben, Collawn, James F., Bartoszewski, Rafal · 2026 · Redox biology
  34. Hypoxia‐inducible factor‐1α in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways
    Swinson, Daniel E.B., Jones, J. Louise, Cox, Giles, Richardson, Donna, Harris, Adrian L., O'Byrne, Kenneth J. · 2004 · International Journal of Cancer