Cited by 1,325Rheumatoid Arthritis Research and TherapiesSpondyloarthritis Studies and TreatmentsGout, Hyperuricemia, Uric Acid

EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis

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Peters, M J L, Symmons, D P M, McCarey, D, Dijkmans, B A C, Nicola, P, Kvien, T K, McInnes, I B, Haentzschel, H +10 more·2010·Annals of the Rheumatic Diseases

Abstract

Objectives To develop evidence-based EULAR recommendations for cardiovascular (CV) risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA).Methods A multidisciplinary expert committee was convened as a task force of the EULAR Standing Committee for Clinical Affairs (ESCCA), comprising 18 members including rheumatologists, cardiologists, internists and epidemiologists, representing nine European countries. Problem areas and related keywords for systematic literature research were identified. A systematic literature research was performed using MedLine, Embase and the Cochrane library through to May 2008. Based on this literature review and in accordance with the EULAR's "standardised operating procedures", the multidisciplinary steering committee formulated evidence-based and expert opinion-based recommendations for CV risk screening and management in patients with inflammatory arthritis.Results Annual CV risk assessment using national guidelines is recommended for all patients with RA and should be considered for all patients with AS and PsA. Any CV risk factors identified should be managed according to local guidelines. If no local guidelines are available, CV risk management should be carried out according to the SCORE function. In addition to appropriate CV risk management, aggressive suppression of the inflammatory process is recommended to further lower the CV risk.Conclusions Ten recommendations were made for CV risk management in patients with RA, AS and PsA. The strength of the recommendations differed between RA on the one hand, and AS and PsA, on the other, as evidence for an increased CV risk is most compelling for RA.

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Crossref · 10.1136/ard.2009.113696

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  • Autoimmune diseases including rheumatoid arthritis, SLE, psoriasis, and antiphospholipid syndrome are characterized by enhanced atherosclerosis and higher cardiovascular morbidity and mortality than the general population.

    “Autoimmune diseases, including rheumatoid arthritis, SLE, psoriasis, and antiphospholipid syndrome, are characterized by enhanced atherosclerosis and consequently higher CV morbidity and mortality rates compared with the general population.186 -188”

    From ESC/EAS Guidelines for the management of dyslipidaemias (2011) · cites this paper as [186]

  • Autoimmune diseases including rheumatoid arthritis, SLE, psoriasis, and anti-phospholipid syndrome are characterized by enhanced atherosclerosis and higher CV morbidity and mortality compared with the general population.

    “Autoimmune diseases, including rheumatoid arthritis, SLE, psoriasis and anti-phospholipid syndrome, are characterized by enhanced atherosclerosis and consequently higher CV morbidity and mortality rates compared with the general population. 383-385”

    From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [385]

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Research works printed but not linked: 4

  1. del Rincon I, Williams K, Stern MP, et al. High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 2001;44:2737-45.
  2. Jacobsson LT, Turesson C, Hanson RL, et al. Joint swelling as a predictor of death from cardiovascular disease in a population study of Pima Indians. Arthritis Rheum 2001;44:1170-6.
  3. Ward MM. Recent improvements in survival in patients with rheumatoid arthritis: better outcomes or different study designs? Arthritis Rheum 2001;44:1467-9.
  4. Gabriel SE, Crowson CS, Kremers HM, et al. Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years. Arthritis Rheum 2003;48:54-8.

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Authors
Peters, M. J. L., Symmons, D. P. M., McCarey, D., Dijkmans, B. A. C., Nicola, P., Kvien, T. K., McInnes, I. B., Haentzschel, H., Gonzalez-Gay, M. A., Provan, S., Semb, A., Sidiropoulos, P., Kitas, G., Smulders, Y. M., Soubrier, M., Szekanecz, Z., Sattar, N., & Nurmohamed, M. T.
Affiliations
  • Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
  • University of Manchester (GB)
  • Glasgow Royal Infirmary (GB)
  • University of Lisbon (PT)
  • Diakonhjemmet Hospital (NO)
  • University of Glasgow (GB)
  • University Hospital Leipzig (DE)
  • University of Crete (GR)
  • Russells Hall Hospital (GB)
  • Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
  • University of Debrecen (HU)
Corresponding author
Nurmohamed, M T
Venue
Annals of the Rheumatic Diseases
Publisher
Elsevier BV
Published
2010-02
Volume
69
Issue
2
Pages
325-331
ISSN
0003-4967 (ISSN-L)
OpenAlex
W2170108033
Cited by
1,325
References
107
Citations by year
2026: 26 · 2025: 35 · 2024: 46 · 2023: 36 · 2022: 44 · 2021: 54 · 2020: 62 · 2019: 57 · 2018: 78 · 2017: 121 · 2016: 153 · 2015: 120 · 2014: 123 · 2013: 107 · 2012: 129
FWCI
62.20
Type
journal article
Language
en
Open access
Locations
  • Annals of the Rheumatic Diseases (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • Research Explorer (The University of Manchester) (submittedVersion)
  • Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
  • University of Debrecen Electronic Archive (University of Debrecen) (submittedVersion)
  • University of Debrecen Electronic Archive (University of Debrecen) (submittedVersion, other-oa)
  • HighWire Press Open Archive (submittedVersion)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Funders
  • Vrije Universiteit Amsterdam
  • European League Against Rheumatism
Topics
  • Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
  • Health Sciences › Medicine › Rheumatology › Spondyloarthritis Studies and Treatments
  • Health Sciences › Medicine › Nephrology › Gout, Hyperuricemia, Uric Acid
Keywords
cardiovascular risk management, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, inflammatory arthritis, cardiovascular risk screening, cardiovascular risk factors, inflammation reduction, EULAR recommendations
MeSH terms
Anti-Inflammatory Agents, Non-Steroidal, Antihypertensive Agents, Arthritis, Rheumatoid, Cardiovascular Diseases, Cholesterol, Drug Administration Schedule, Female, Glucocorticoids, Humans, Male, Risk Management, Spondylitis, Ankylosing, Arthritis, Psoriatic, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Evidence-Based Medicine

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