What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

Davey Smith, G., & Ebrahim, S. (2003) · International Journal of Epidemiology · doi:10.1093/ije/dyg070 · Cited by 5,882

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

Wald, D. S., Law, M., & Morris, J. K. (2002) · BMJ · doi:10.1136/bmj.325.7374.1202 · Cited by 1,945

A strategy to reduce cardiovascular disease by more than 80%

Wald, N., & Law, M. R. (2003) · BMJ · doi:10.1136/bmj.326.7404.1419 · Cited by 1,565

Mendelian randomization: prospects, potentials, and limitations

Smith, G. D. (2004) · International Journal of Epidemiology · doi:10.1093/ije/dyh132 · Cited by 1,222

Problems of reporting genetic associations with complex outcomes

Colhoun, H. M., McKeigue, P., & Smith, G. D. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12715-8 · Cited by 1,203

5, 10-Methylenetetrahydrofolate Reductase Gene Variants and Congenital Anomalies: A HuGE Review

Botto, L. D., & Yang, Q. (2000) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a010290 · Cited by 1,045

Epidemiological methods for studying genes and environmental factors in complex diseases

Clayton, D. G., & McKeigue, P. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06418-2 · Cited by 469

Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?

Lawlor, D. A., Smith, G. D., Bruckdorfer, K. R., Kundu, D., & Ebrahim, S. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16260-0 · Cited by 438

Rise and fall of modern medicine

Fanu, J. L. (1999) · The Lancet · doi:10.1016/s0140-6736(05)75559-8 · Cited by 298

Aldehyde Dehydrogenase 2 Gene Is a Risk Factor for Myocardial Infarction in Japanese Men.

Takagi, S., Iwai, N., Yamauchi, R., Kojima, S., Yasuno, S., Baba, T., Terashima, M., Tsutsumi, Y., Suzuki, S., Morii, I., et al. (2002) · Hypertension Research · doi:10.1291/hypres.25.677 · Cited by 144

Proteogenomic signature of risk of Alzheimer’s disease and related dementia risk in individuals with a history of major depression disorderPreprint

Diniz, B. S., Chen, Z., Steffens, D. C., Pilling, L. C., Fortinsky, R. H., Kuchel, G. A., & Kuo, C. (2024) · medRxiv · doi:10.1101/2024.09.11.24313493 · Cited by 3

Investigating the association between anthropometry and colorectal cancer survival: a two-sample Mendelian randomization analysis

Kanellopoulou, A., Bouras, E., Chan, A. T., Marchand, L. L., Wolk, A., Wu, A. H., Gunter, M. J., Nimptsch, K., Haycock, P., Lewis, S. J., et al. (2025) · International Journal of Epidemiology · doi:10.1093/ije/dyaf193 · Cited by 2

Bidirectional Mendelian randomization and cross-sectional study reveal depression as a causal risk factor for endometriosis

Jiang, L., Jiang, L., & Ma, S. (2025) · Medicine · doi:10.1097/md.0000000000045729 · Cited by 2

Biostatistical Methods in Pharmacoepidemiology

Macedo, A. F., Rodriguez, A. M., Hawkes, W., & Fabre, A. (2020) · Springer eBooks · doi:10.1007/978-3-030-48555-9_4 · Cited by 2

Narrative Identity in the Social World

McLean, K. C., Syed, M., Haraldsson, K. G., & Lowe, L. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.035 · Cited by 2

Personality and Crime

Lynam, D. R., Vize, C. E., & Miller, J. D. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.043 · Cited by 2

Traits and Dynamic Processes

Jayawickreme, E., & Zachry, C. E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.032 · Cited by 2

The Causal Effect of Gut Microbiota on the Development of Idiopathic Normal Pressure Hydrocephalus

Zhang, H., Mao, W., & Zhang, Y. (2023) · World Neurosurgery · doi:10.1016/j.wneu.2023.11.024 · Cited by 2

Pharmacogenomics-based systematic review of coronary artery disease based on personalized medicine procedure

Asl, S. K., Rahimzadegan, M., & Asl, A. K. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e28983 · Cited by 2

The association between telomere length and blood lipids: a bidirectional two-sample Mendelian randomization study

Yang, S., Wang, X., Li, Y., Zhou, L., Guo, G., & Wu, M. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1338698 · Cited by 2

Causal Effects of Asthma on Upper Airway Diseases and Allergic Diseases: A Two-Sample Mendelian Randomization

Zhang, Z., Li, G., Zhou, S., Wang, M., Yu, L., & Jiang, Y. (2024) · International Archives of Allergy and Immunology · doi:10.1159/000540358 · Cited by 2

Application of Mendelian randomization in thyroid diseases: a review

Li, Z., Wang, R., Liu, L., Jia, Z., Zhou, P., & He, Q. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1472009 · Cited by 2

Lipids, lipid-lowering drugs and the risk of herpes zoster: a Mendelian randomization study

Che, Y., Yuan, J., & Guo, J. (2025) · Archives of Dermatological Research · doi:10.1007/s00403-024-03600-1 · Cited by 2

Pharmacovigilance study and genetic target prediction analysis of FDA adverse event reports (FAERS) for drug-induced sinusitis

Wang, E., Sun, Y., Zhao, H., & Cao, Z. (2025) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2025.2484474 · Cited by 2

Population Genetics and Pharmacogenetics

Ong, K. K., & Elks, C. E. (2010) · Yearbook of pediatric endocrinology · doi:10.1159/000320661 · Cited by 2

Using molecular genetic information to infer causality in observational data: Mendelian randomisation

Taylor, A. E., Ware, J. J., Gage, S. H., Smith, G. D., & Munafo, M. R. (2014) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2014.08.002 · Cited by 2

A Summary of Recent Updates on the Genetic Determinants of Depression

Dunn, E. C., Wang, M., & Perlis, R. H. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-58131-8.00001-x · Cited by 5

Attachment Theory

Mikulincer, M., & Shaver, P. R. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.020 · Cited by 4

Examining the causal association between moderate alcohol consumption and cardiovascular risk factors in the Taiwan Biobank: a Mendelian randomization analysis

Chien, P.-S., Wong, T., Tai, A., Shr, Y., & Yu, T. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1456777 · Cited by 2

Models of Physical Health and Personality

Heilmayr, D., & Friedman, H. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.019 · Cited by 2

Risk Factors for Falls and Fall-related Fractures in the Elderly

Ziere, G. J. (2007) · RePub (Erasmus University Rotterdam) · Cited by 2

Commentary: From handles to interventions. Commentary on R G Collingwood, 'The so-called idea of causation'

Woodward, J. (2014) · International Journal of Epidemiology · doi:10.1093/ije/dyu131 · Cited by 2

New Pathway for Tissue-Type Plasminogen Activator Regulation

Chasman, D. I. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.303499 · Cited by 2

Logical Analysis of Response of Health Officials’ Worldwide, to Cost-Effective Early Remedies for COVID19Preprint

Wimalawansa, S. J., & Polonowita, A. K. (2022) · Preprints.org · doi:10.20944/preprints202210.0135.v1 · Cited by 1

Mood instability may be causally associated with the high risk of cardiovascular disease: evidence from a mendelian randomization analysisPreprint

Liu, Z., Wang, H., Yang, Z., Yu, L., Wang, J., & Zou, C. (2023) · medRxiv · doi:10.1101/2023.08.29.23294761 · Cited by 2

Determinanten van ziekte en gezondheid op hoge leeftijd: Nieuwe inzichten uit de Leidse verouderingsstudies

de Craen, A. J. M., Oleksik, A. M., Maier, A. B., & Westendorp, R. G. J. (2009) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.1007/bf03088517 · Cited by 1

Epidemiological criteria and risk factors for type two diabetes mellitus (T2DM) in children and adolescents: Can we modify them?

Soliman, N. A., Huseth‐Zosel, A. L., & Soliman, A. T. (2022) · World Journal of Advanced Research and Reviews · doi:10.30574/wjarr.2022.16.1.1010 · Cited by 3

Sexual behavior and cardiovascular diseases: univariable and multivariable Mendelian randomization

Zhu, K., Lin, Z., Luo, Q., Jiang, Z., He, R., Wu, H., Yu, J., Liu, X., Sheng, J., Zhu, H., et al. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1250404 · Cited by 1

An Introduction to Some Advanced Topics

Rothman, K. J., Huybrechts, K. F., & Murray, E. J. (2024) · Oxford University Press eBooks · doi:10.1093/oso/9780197751541.003.0015 · Cited by 1

Exploring the causal relationship between hemoglobin and pancreatic cancer and its potential mechanisms through bioinformatics and Mendelian randomization

Wang, S., Huang, S., Ren, X., Zhang, H., Tian, Y., Luo, Z., & Wang, H. (2025) · Discover Oncology · doi:10.1007/s12672-025-03352-y · Cited by 1

Integrating Mendelian Randomization and Machine Learning to Identify Hypoxia-Related Diagnostic Biomarkers and Causal Relationship in COPD

Fu, W., Liu, Y., Li, R., & Jin, H. (2025) · International Journal of COPD · doi:10.2147/copd.s524381 · Cited by 1

Mendelian randomization and nomogram-based prediction of hepatocellular carcinoma risk in patients with hepatitis B cirrhosis

Zheng, X., Hong, Y., & Wei, W. (2025) · PeerJ · doi:10.7717/peerj.20179 · Cited by 1

Association between immune cells and multiple cancers: Insights from Mendelian randomization and gene-based analysis

Tang, M., Cui, H., Wu, X., Wang, Y., Zhao, X., Xiang, R., Xiao, J., Chen, L., Zou, Y., Liu, Y., et al. (2026) · iScience · doi:10.1016/j.isci.2025.114618 · Cited by 1

Lipid-lowering and glucose-lowering drug targets differentially modulate antipsychotic treatment efficacy in schizophrenia

Zhu, Y., Yuan, R., Lu, Z., Zhang, Y., Kang, Z., Feng, X., Zhao, G., Sun, J., Guo, J., Yu, T., et al. (2026) · Cell Reports Medicine · doi:10.1016/j.xcrm.2026.102653 · Cited by 1

Higher Body Mass Index Is a Causal Risk Factor for Skin Infections: A Mendelian Randomisation Study Using UK Biobank and FinnGen

Hopkins, R., de Villiers, E., Weedon, M. N., Shields, B. M., Dennis, J., McGovern, A. P., & Green, H. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70797 · Cited by 1

Antihypertensive Treatment and Risk of Metabolic Associated Fatty Liver Disease: A Drug-Target Mendelian Randomization

Hu, Y., Smith-Byrne, K., Bidel, Z., Xiao, X., Zhao, X., Dehghan, A., Canoy, D., Wamil, M., Conrad, N., Rao, S., et al. (2026) · Hypertension · doi:10.1161/hypertensionaha.126.27526 · Cited by 1

Human genetics shines a light on ischaemic stroke

Voight, B. F., & Rader, D. J. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00400-7 · Cited by 1

Further Direction of Research and Policy Making of Environment and Children’s Health

Kishi, R., & Araki, A. (2019) · Current topics in environmental health and preventive medicine · doi:10.1007/978-981-15-0520-1_22 · Cited by 1

Immunotherapies for Depression

Kappelmann, N., Bullmore, E. T., & Khandaker, G. M. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108539623.009 · Cited by 1

Genetics of Personality

Sallis, H., Smith, G. D., & Munafo, M. R. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.024 · Cited by 1

Self-Regulation and Control in Personality Functioning

Carver, C. S., & Scheier, M. F. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.029 · Cited by 1

Association between n-3 PUFA and lung function: results from the NHANES 2007–2012 and Mendelian randomisation study

Li, J., Sun, J., Liu, L., Zhang, C., & Liu, Z. (2024) · British Journal Of Nutrition · doi:10.1017/s0007114524000266 · Cited by 1

Causal effect of porphyria biomarkers on alcohol-related hepatocellular carcinoma through Mendelian Randomization

Yang, X., Wang, S., Sun, C., & Xia, Y. (2024) · PLoS ONE · doi:10.1371/journal.pone.0299536 · Cited by 1

Genetic susceptibility to breast cancer increases the risk of neutropenia and agranulocytosis: insights from Mendelian randomization

Wei, C., Zhang, G., Li, C., & Zeng, J. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08682-1 · Cited by 1

Identification and functionalization of thyrotropin receptor antibodies with different antigenic epitopes

Zheng, J., Duan, H., Jiang, Z., Chen, L., You, S., Huang, L., & Huang, H. (2024) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00123.2024 · Cited by 1

Allopurinol is Associated with an Increased Risk of Cerebral Infarction: A Two-Sample Mendelian Randomization Study

Ma, X., Shi, M.-F., Feng, W., Chen, S., Zhong, X., Lin, C., & Xu, Q. (2024) · ACS Omega · doi:10.1021/acsomega.4c03483 · Cited by 1

Influence of intraocular and blood pressure on brain volumes: Observational and Mendelian randomization analyses

Shang, X., Huang, Y., Zhu, S., Zhu, Z., Zhang, X., Wang, W., Zhang, X., Liu, J., Liu, J., Tang, S., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110817 · Cited by 1

Blood-based inflammatory markers in female infertility: evidence from Mendelian randomization analysis

Alesi, S., Teede, H. J., Enticott, J., Silva, K. D., & Mousa, A. (2024) · F&S Science · doi:10.1016/j.xfss.2024.11.001 · Cited by 1

Extensions to Mendelian randomization

Palmer, T. (2009) · Cited by 1

Genetics and Genomics of Coronary Artery Disease

Yamada, Y., & Yasukochi, Y. (2018) · Springer eBooks · doi:10.1007/978-3-319-66114-8_22 · Cited by 1

What can we learn from psoriasis pharmacogenomics research?

Sanclemente, G. (2018) · British Journal of Dermatology · doi:10.1111/bjd.16065 · Cited by 1

Personality in Nonhuman Animals

Bell, A. M., & Bensky, M. K. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.023 · Cited by 1

The Trait Approach

Weiß, A., & Deary, I. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.005 · Cited by 2

Personality and the Unconscious

Perugini, M., Richetin, J., & Costantini, G. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.008 · Cited by 2

Alcohol consumption as a risk factor for colorectal cancer : an epidemiological study on genetic susceptibility and molecular endpoints

Bongaerts, B. W. C. (2008) · doi:10.26481/dis.20081016bb · Cited by 1

Epidemiology of Inhibitors

van der Bom, J. G. (2011) · doi:10.1002/9781119979401.ch13 · Cited by 1

Anxiety Disorders and Depression in Older Adults

Hek, K. (2013) · RePub (Erasmus University Rotterdam) · Cited by 1

Five Authors Reply

Bilal, U., Fernández, E., Navas‐Acién, A., Bolúmar, F., & Franco, M. (2014) · American Journal of Epidemiology · doi:10.1093/aje/kwu185 · Cited by 1

Using Natural Experiments to Test Environmental Mediation Hypotheses

Rutter, M. L., & Thapar, A. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy104 · Cited by 1

Category theory for genetics II: genotype, phenotype and haplotypePreprint

Tuyéras, R. (2018) · arXiv (Cornell University) · doi:10.48550/arxiv.1805.07004 · Cited by 1

Preface

Corr, P. J., & Matthews, G. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.001 · Cited by 1

Addendum: Statistical Analyses and Computer Programming in Personality

Corr, P. J., & Matthews, G. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.045 · Cited by 1

RE: "ALCOHOL CONSUMPTION IN YOUNG ADULTS AND INCIDENT HYPERTENSION: 20-YEAR FOLLOW-UP FROM THE CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS STUDY"

Leon, D. A., Casas, J.-P., Dale, C. E., Polikina, O., Tomkins, S., & McKee, M. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq235 · Cited by 1

A Step Toward Disentangling the Complex Relationship Between Vitamin D and Kidney Function

Teumer, A., & Rebholz, C. M. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad050 · Cited by 1

Diabetes, glycaemic profile and risk of vitiligo: a Mendelian randomisation studyPreprint

Hu, S., Che, Y., Cai, J., Guo, J., & Zeng, J. (2023) · medRxiv · doi:10.1101/2023.10.30.23297752 · Cited by 1

Investigating Causes of Disease

Lawlor, D. A., & Macleod, J. (2013) · doi:10.1002/9781394322022.ch7 · Cited by 1

Bidirectional relationships between mental health problems and urinary incontinence in women: a two-sample Mendelian randomization analysisPreprint

Knight, R., Soares, A. G., Burrows, K., Fraser, A., Palmer, T., Cartwright, R., & Joinson, C. J. (2026) · medRxiv · doi:10.64898/2026.02.06.26345734 · Cited by 1

Multistage Genetic Association Studies

Thomas, D. C., & Conti, D. V. (2014) · Wiley StatsRef: Statistics Reference Online · doi:10.1002/9781118445112.stat06925

Folate - Associations with breast cancer depending on intake, metabolism, genetic variation and estrogen receptor status.

Ericson, U. (2010) · Lund University Publications (Lund University)

Lipid-related genes and their associations with coronary heart disease

Song, C. (2014) · Figshare

[Causality can be shown with mendelian randomization. Cardiovascular risk relations tested with the method].

Nilsson, P. M. (2013) · PubMed

C-reactive protein as a marker of cardiovascular risk. Chicken, egg or turkey?

Karet, B. (2008) · Primary Care Cardiovascular Journal (PCCJ) · doi:10.3132/pccj.2008.036

Mendelian Randomisation: Inferring the causal relationship between urate and associated biochemical and phenotypic parameters.

Hughes, K. B. (2013) · Otago University Research Archive (University of Otago)

Statistical Perspectives on Data Mining

Maindonald, J. H. (2006)

Integrating longitudinal twin research and measured genetic variation to test developmental theories of behavioral disinhibition and adolescent substance use.

Vrieze, S. I. (2012) · University of Minnesota Digital Conservancy (University of Minnesota)

Lipid-related Genes and Their Associations with Coronary Heart Disease

Ingelsson, E., Pedersen, N. L., Hägg, D. S., Orho‐Melander, M., Lindahl, B., Czene, K., & Orsini, D. N. (2014)

Untersuchung des Zusammenhangs der alimentären Fettsäurezufuhr und des Fettsäurestatus in Erythrozyten mit dem Risiko für Typ-2-Diabetes mellitus in der EPIC-Potsdam-Studie

Kröger, J. (2011) · DepositOnce · doi:10.14279/depositonce-2833

Elevated serum urate is a potential factor in reduction of total bilirubin: a Mendelian randomization study

Zhang, H., Liu, J., Dong, Z., Ding, Y., Qian, Q., Zhou, J., Ma, Y., Mei, Z., Chen, X., Li, Y., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.21977

Genetic Polymorphisms in Fructokinase and Aldolase B, and Biomarkers of the Metabolic Syndrome

Deljoomanesh, N. (2017) · TSpace (University of Toronto)

Personality Assessment Methods

Boyle, G. J., & Helmes, E. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.011 · Cited by 1

Personality and Intelligence

Schermer, J. A., & Saklofske, D. H. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.014

Social Relations and Social Support

Austin, E. Q., Knack, J. M., Jensen‐Campbell, L. A., & Rex‐Lear, M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.036

Exploiting genetics to understand paediatric eye disorders

Plotnikov, D. (2020) · ORCA Online Research @Cardiff (Cardiff University)

FIVE AUTHORS REPLY

Halanych, J. H., Safford, M. M., Kertesz, S. G., Person, S. D., & Kiefe, C. I. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq237

阅读孟德尔随机化研究：临床医生的指南，词汇表和清单

Davies., 尼., 迈克尔五福尔摩斯, & 乔治戴维斯史密斯 (2018)

The role of anti-Müllerian hormone in the etiology of cancer and cardiometabolic diseases

Verdiesen, R. M. G. (2021) · Utrecht University Repository (Utrecht University) · doi:10.33540/617

Examining risk factors for weight change during midlife: A Mendelian randomization studyPreprint

Power, G. M., Tyrrell, J., Gkatzionis, A., Fang, S., Heron, J., Smith, G. D., & Richardson, T. G. (2021) · medRxiv · doi:10.1101/2021.07.21.21260895

General Introduction

Corr, P. J., & Matthews, G. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.002

Epidemiological Methods

Rosano, A., & Robert‐Gnansia, E. (2007) · Environmental science and technology library · doi:10.1007/1-4020-4831-9_3

Genetic Epidemiology

Campbell, H. J., & Anderson, N. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803678-5.00172-7

Genetic Epidemiology

Campbell, H., & Anderson, N. (2008) · Elsevier eBooks · doi:10.1016/b978-012373960-5.00203-3

Faculty Opinions recommendation of A meta-review of "lifestyle psychiatry": the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders.

Beesdo‐Baum, K. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.738680951.793580928

Index

Corr, P. J., & Matthews, G. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108264822.046

Assessment of the causal relationship between depression and traits of sarcopenia: A bidirectional two-sample Mendelian randomization studyPreprint

Tan, J., Kong, Y., Ai, M., Hong, S. L., Zhang, Y., & Kuang, L. (2023) · Research Square · doi:10.21203/rs.3.rs-2657221/v1

Intraocular pressure, systemic blood pressure, and brain volumes: observational and Mendelian Randomization analysesPreprint

Shang, X., Huang, Y., Zhu, S., Zhu, Z., Zhang, X., Wang, W., Zhang, X., Liu, J., Liu, J., Tang, S., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2798166/v1

Telomere Attrition and Epigenetic Aging and Risk for Haematologic Diseases: A Multivariable Mendelian Randomisation AnalysisPreprint

Li, Y., Chen, J., Sun, T., Fu, R., Liu, X. F., Xue, F., Liu, W., Chen, Y., Ju, M., Dai, X., et al. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4593211

Causal Relationships between Common Autoimmune Disease and Carpal Tunnel Syndrome: Study of Univariable and Multivariable Mendelian Randomization.Preprint

Tan, X., & Chen, S. (2023) · Research Square · doi:10.21203/rs.3.rs-3456971/v1

Genetically Determined Telomere Length and Risk for Haematologic Diseases: Results from Large Prospective Cohorts and Mendelian Randomization AnalysisPreprint

Zhang, L., Li, Y., Chen, J., Sun, T., Fu, R., Liu, X. F., Xue, F., Liu, W., Chen, Y., Ju, M., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-3866462/v1

Exploring the causality and pathogenesis of Type 2 diabetes in gastric cancer based on Mendelian randomization and transcriptome data analysesPreprint

Ma, J., Gao, Y., Hou, S., Ma, N., Cui, S., Zhang, Z., Li, W., & Zhu, J. (2024) · Research Square · doi:10.21203/rs.3.rs-4171771/v1

Mendelian randomisation empowers epidemiology

(2005) · BMJ · doi:10.1136/bmj.330.7499.0-d

Mendelian Randomization for Strengthening Causal Inference in Observational Studies

Smith, G. D. (2010) · Perspectives on Psychological Science · doi:10.1177/1745691610383505 · Cited by 186

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

Davey Smith, G., & Ebrahim, S. (2003) · International Journal of Epidemiology · doi:10.1093/ije/dyg070 · Cited by 5,882

Mendelian Randomization in the Era of Genomewide Association Studies

Abou‐Sleiman, P. M., & Grant, S. F. A. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2009.141564 · Cited by 123

Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?

Ebrahim, S., & Davey Smith, G. (2008) · Human Genetics · doi:10.1007/s00439-007-0448-6 · Cited by 410