Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials
Open accessAbstract
OBJECTIVE: To examine whether statins can reduce the risk of atrial fibrillation. DESIGN: Meta-analysis of published and unpublished results from larger scale statin trials, with comparison of the findings against the published results from smaller scale or shorter duration studies. DATA SOURCES: Medline, Embase, and Cochrane's CENTRAL up to October 2010. Unpublished data from longer term trials were obtained through contact with investigators. STUDY SELECTION: Randomised controlled trials comparing statin with no statin or comparing high dose versus standard dose statin; all longer term trials had at least 100 participants and at least six months' follow-up. RESULTS: In published data from 13 short term trials (4414 randomised patients, 659 events), statin treatment seemed to reduce the odds of an episode of atrial fibrillation by 39% (odds ratio 0.61, 95% confidence interval 0.51 to 0.74; P < 0.001), but there was significant heterogeneity (P < 0.001) between the trials. In contrast, among 22 longer term and mostly larger trials of statin versus control (105,791 randomised patients, 2535 events), statin treatment was not associated with a significant reduction in atrial fibrillation (0.95, 0.88 to 1.03; P = 0.24) (P<0.001 for test of difference between the two sets of trials). Seven longer term trials of more intensive versus standard statin regimens (28,964 randomised patients and 1419 events) also showed no evidence of a reduction in the risk of atrial fibrillation (1.00, 0.90 to 1.12; P = 0.99). CONCLUSIONS: The suggested beneficial effect of statins on atrial fibrillation from published shorter term studies is not supported by a comprehensive review of published and unpublished evidence from larger scale trials.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Statin treatment does not prevent atrial fibrillation in other settings.
“Statin treatment does not prevent AF in other settings.692,693”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [692]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
R: A Language and Environment for Statistical Computing
R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works
Atrial fibrillation as an independent risk factor for stroke: the Framingham study
Wolf, P. A., Abbott, R. D., & Kannel, W. B. (1991) · Stroke · doi:10.1161/01.str.22.8.983 · Cited by 7,388 · see citing works
Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
Ridker, P. M., Danielson, E., Fonseca, F. A. H., Genest, J., Gotto, A. M., Kastelein, J. J. P., Koenig, W., Libby, P., Lorenzatti, A. J., MacFadyen, J. G., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0807646 · Cited by 6,674 · see citing works
Downs, J. R., Clearfield, M., Weis, S., Whitney, E., Shapiro, D. R., Beere, P. A., Langendorfer, A., Stein, E. A., Kruyer, W., Gotto, Jr., et al. (1998) · JAMA · doi:10.1001/jama.279.20.1615 · Cited by 5,236 · see citing works
Sever, P., Dahlöf, B., Poulter, N. R., Wedel, H., Beevers, G., Caulfield, M. J., Collins, R., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12948-0 · Cited by 3,757 · see citing works
Colhoun, H. M., Betteridge, D. J., Durrington, P. N., Hitman, G. A., W Neil, H. A., Livingstone, S. J., Thomason, M. J., Mackness, M. I., Charlton-Menys, V., & Fuller, J. H. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16895-5 · Cited by 3,755 · see citing works
Rosuvastatin to Prevent Vascular Events in Men and Women With Elevated C-Reactive Protein
Ridker, P. M., Danielson, E., Fonseca, F. A. H., Genest, J. J., Gotto, A. M., Kastelein, J. J. P., Köenig, W., Libby, P., Lorenzatti, A. J., MacFadyen, J. G., et al. (2009) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000344393.60303.0a · Cited by 3,641 · see citing works
Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease
LaRosa, J. C., Grundy, S. M., Waters, D. D., Shear, C., Barter, P., Fruchart, J.-C., Gotto, A. M., Greten, H., Kastelein, J. J. P., Shepherd, J., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050461 · Cited by 3,489 · see citing works
Beta blockade during and after myocardial infarction: An overview of the randomized trials
Yusuf, S., Peto, R., Lewis, J., Collins, R., & Sleight, P. (1985) · Progress in Cardiovascular Diseases · doi:10.1016/s0033-0620(85)80003-7 · Cited by 3,205 · see citing works
Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis
Wanner, C., Krane, V., März, W., Olschewski, M., Mann, J. F. E., Ruf, G., & Ritz, E. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043545 · Cited by 2,614 · see citing works
Wang, T. J., Larson, M. G., Levy, D., Vasan, R. S., Leip, E. P., Wolf, P. A., D’Agostino, R. B., Murabito, J. M., Kannel, W. B., & Benjamin, E. J. (2003) · Circulation · doi:10.1161/01.cir.0000072767.89944.6e · Cited by 1,970 · see citing works
Better Reporting of Harms in Randomized Trials: An Extension of the CONSORT Statement
Ioannidis, J. P. A., Evans, S. J. W., Gøtzsche, P. C., O'Neill, R. T., Altman, D. G., Schulz, K., Moher, D., & for the CONSORT Group* (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-141-10-200411160-00009 · Cited by 1,593 · see citing works
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-499_7 · Cited by 1,583 · see citing works
Atrial Fibrillation: A Major Contributor to Stroke in the Elderly
Wolf, P. A. (1987) · Archives of Internal Medicine · doi:10.1001/archinte.147.9.1561 · Cited by 1,526 · see citing works
Nakamura, H., Arakawa, K., Itakura, H., Kitabatake, A., Goto, Y., Toyota, T., Nakaya, N., Nishimoto, S., Muranaka, M., Yamamoto, A., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69472-5 · Cited by 941 · see citing works
A meta-analysis of randomized controlled trials: Efficacy of selenium treatment for sepsis
Li, S., Tang, T., Guo, P., Zou, Q., Ao, X., Hu, L., & Tan, L. (2019) · Medicine · doi:10.1097/md.0000000000014733 · Cited by 802 · see citing works
Serruys, P. W. J. C. (2002) · JAMA · doi:10.1001/jama.287.24.3215 · Cited by 716 · see citing works
Publication bias and clinical trials
Dickersin, K., Chan, S., Chalmersx, T. C., Sacks, H. S., & Smith, H. (1987) · Controlled Clinical Trials · doi:10.1016/0197-2456(87)90155-3 · Cited by 715 · see citing works
Crouse, J. R., Raichlen, J. S., Riley, W. A., Evans, G. W., Palmer, M. K., O’Leary, D. H., Grobbee, D. E., Bots, M. L., & for the METEOR Study Group (2007) · JAMA · doi:10.1001/jama.297.12.1344 · Cited by 708 · see citing works
Quality of life in patients with atrial fibrillation: a systematic review
Thrall, G., Lane, D., Carroll, D., & Lip, G. Y. H. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.10.057 · Cited by 697 · see citing works
Atrial Fibrillation and Heart Failure
Anter, E., Jessup, M. L., & Callans, D. J. (2009) · Circulation · doi:10.1161/circulationaha.108.821306 · Cited by 680 · see citing works
ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation: full text
Fuster, V., Rydén, L., Cannom, D. S., Crijns, H. J. G. M., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Heuzey, J. L., Kay, G. N., Lowe, J. E., et al. (2006) · EP Europace · doi:10.1093/europace/eul097 · Cited by 663 · see citing works
Patti, G., Chello, M., Candura, D., Pasceri, V., D’Ambrosio, A., Covino, E., & Sciascio, G. D. (2006) · Circulation · doi:10.1161/circulationaha.106.621763 · Cited by 617 · see citing works
Cost of an emerging epidemic: an economic analysis of atrial fibrillation in the UK
Stewart, S., Murphy, N., Walker, A., McGuire, A., & McMurray, J. J. V. (2004) · Heart · doi:10.1136/hrt.2002.008748 · Cited by 590 · see citing works
Knopp, R. H., d’Emden, M., Smilde, J. G., Pocock, S. J., & on behalf of the ASPEN Study Group (2006) · Diabetes Care · doi:10.2337/dc05-2415 · Cited by 550 · see citing works
Role of Inflammation in Initiation and Perpetuation of Atrial Fibrillation
Issac, T. T., Dokainish, H., & Lakkis, N. M. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.06.054 · Cited by 525 · see citing works
Effects of Fosinopril and Pravastatin on Cardiovascular Events in Subjects With Microalbuminuria
Asselbergs, F. W., Diercks, G. F. H., Hillege, H. L., Boven, A. J. V., Janssen, W. M. T., Voors, A. A., de Zeeuw, D., de Jong, P. E., van Veldhuisen, D. J., & van Gilst, W. H. (2004) · Circulation · doi:10.1161/01.cir.0000146378.65439.7a · Cited by 517 · see citing works
Prevention of Atrial Fibrillation
Benjamin, E. J., Chen, P., Bild, D. E., Mascette, A. M., Albert, C. M., Alonso, Á., Calkins, H. G., Connolly, S. J., Curtis, A. B., Darbar, D., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.825380 · Cited by 471 · see citing works
Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe
Feldman, H. H., Doody, R. S., Kivipelto, M., Sparks, D. L., Waters, D. D., Jones, R. W., Schwam, E., Schindler, R., Hey-Hadavi, J., DeMicco, D. A., et al. (2010) · Neurology · doi:10.1212/wnl.0b013e3181d6476a · Cited by 438 · see citing works
Reliable assessment of the effects of treatment on mortality and major morbidity, I: clinical trials
Collins, R., & MacMahon, S. W. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03651-5 · Cited by 337 · see citing works
Valsartan for Prevention of Recurrent Atrial Fibrillation
Modena, M. G. (2009) · New England Journal of Medicine · doi:10.1056/nejmx090019 · Cited by 328 · see citing works
Sola, S., Mir, M. Q. S., Khan, B. V., Lerakis, S., & Tandon, N. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.06.088 · Cited by 322 · see citing works
Koren, M. J., & Hunninghake, D. B. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.07.053 · Cited by 286 · see citing works
Antiarrhythmic Effect of Statin Therapy and Atrial Fibrillation
Fauchier, L., Pierre, B., de Labriolle, A., Grimard, C., ZANNAD, N., & Babuty, D. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.09.063 · Cited by 271 · see citing works
Majeed, A., Moser, K., & Carroll, K. (2001) · Heart · doi:10.1136/heart.86.3.284 · Cited by 253 · see citing works
Schmermund, A., Achenbach, S. S., Budde, T., Buziashvili, Y. I., Förster, A., Friedrich, G. J., Henein, M., Kerkhoff, G., Knollmann, F. D., Kukharchuk, V. V., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.568147 · Cited by 253 · see citing works
Novel Approaches for Preventing or Limiting Events (Naples) II Trial
Briguori, C., Visconti, G., Focaccio, A., Golia, B., Chieffo, A., Castelli, A., Mussardo, M., Montorfano, M., Ricciardelli, B., & Colombo, A. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.07.005 · Cited by 238 · see citing works
Colhoun, H. M., Betteridge, D. J., & Durrington, P. (2004) · ACC Current Journal Review · doi:10.1016/j.accreview.2004.10.017 · Cited by 233 · see citing works
Effects of atorvastatin on systemic inflammatory response after coronary bypass surgery
Chello, M., Patti, G., Candura, D., Mastrobuoni, S., Sciascio, G. D., Agrò, F. E., Carassiti, M., & Covino, E. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000201407.89977.ea · Cited by 213 · see citing works
Haywood, L. J., Ford, C. E., Crow, R. S., Davis, B. R., Massie, B. M., Einhorn, P. T., & Williard, A. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.08.020 · Cited by 178 · see citing works
Intensive lipid lowering with atorvastatin in patients with stable coronary disease
LaRosa, J. C., Grundy, S. M., & Waters, D. D. (2005) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2005.10.023 · Cited by 165 · see citing works
Effect of rosuvastatin pretreatment on myocardial damage after coronary surgery: A randomized trial
Mannacio, V. A., Iorio, D., Amicis, V. D., Lello, F. D., & Musumeci, F. (2008) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2008.06.038 · Cited by 141 · see citing works
Effect of Atorvastatin on the Recurrence Rates of Atrial Fibrillation After Electrical Cardioversion
Özaydın, M., Varol, E., Aslan, S. M., Küçüktepe, Z., Doğan, A., Öztürk, M., & Altınbaş, A. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.11.082 · Cited by 135 · see citing works
Structural remodeling in atrial fibrillation
Corradi, D., Callegari, S., Maestri, R., Benussi, S., & Alfieri, O. (2008) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio1370 · Cited by 134 · see citing works
Liu, T., Li, L., Korantzopoulos, P. G., Liu, E., & Li, G. (2007) · International Journal of Cardiology · doi:10.1016/j.ijcard.2007.07.137 · Cited by 134 · see citing works
Analysis of pravastatin to prevent recurrence of atrial fibrillation after electrical cardioversion
Tveit, A., Grundtvig, M., GUNDERSEN, T., Vanberg, P., Semb, A. G., Holt, E., & Gullestad, L. L. (2004) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2003.12.009 · Cited by 132 · see citing works
Koren, M. J., & Hunninghake, D. B. (2005) · ACC Current Journal Review · doi:10.1016/j.accreview.2004.12.117 · Cited by 130 · see citing works
Rahimi, K., Malhotra, A., BANNING, A. P., & Jenkinson, C. (2010) · BMJ · doi:10.1136/bmj.c5707 · Cited by 129 · see citing works
Nissen, S. E. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.07.013 · Cited by 120 · see citing works
Effect of C-reactive protein reduction on paroxysmal atrial fibrillation
Dernellis, J. M., & Panaretou, M. (2005) · American Heart Journal · doi:10.1016/j.ahj.2005.06.032 · Cited by 119 · see citing works
Song, Y. B., On, Y. K., Kim, J. H., Shin, D., Kim, J. S., Sung, J., Lee, S. H., Kim, W. S., & Lee, Y. T. (2008) · American Heart Journal · doi:10.1016/j.ahj.2008.04.020 · Cited by 116 · see citing works
Effects of rosuvastatin on atrial fibrillation occurrence: ancillary results of the GISSI-HF trial
Maggioni, A. P., Fabbri, G., Lucci, D., Marchioli, R., Franzosi, M. G., Latini, R., Nicolosi, G. L., Porcu, M., Cosmi, F., Stefanelli, S., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp357 · Cited by 100 · see citing works
Rahimi, K., BANNING, A. P., Cheng, A. S. H., Pegg, T. J., Karamitsos, T. D., Channon, K. M., Darby, S. C., Taggart, D. P., Neubauer, S., & Selvanayagam, J. B. (2009) · Heart · doi:10.1136/hrt.2009.173302 · Cited by 98 · see citing works
Howard, W. J. (2007) · Yearbook of Endocrinology · doi:10.1016/s0084-3741(08)70060-x · Cited by 98 · see citing works
Ji, Q., Mei, Y., Wang, X., Sun, Y., Feng, J., Cai, J., Xie, S., & Chi, L. (2009) · Circulation Journal · doi:10.1253/circj.cj-09-0352 · Cited by 84 · see citing works
Prevention of Atrial Fibrillation With 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors
Adam, O., Neuberger, H., Böhm, M., & Laufs, U. (2008) · Circulation · doi:10.1161/circulationaha.107.760892 · Cited by 73 · see citing works
The incidence and risk factors for new onset atrial fibrillation in the PROSPER study
Macfarlane, P. W., Murray, H. M., Sattar, N. A., Stott, D. J., Ford, I., Buckley, B. M., Jukema, J. W., Westendorp, R. G. J., & Shepherd, J. (2011) · EP Europace · doi:10.1093/europace/eur016 · Cited by 65 · see citing works
Almroth, H., Höglund, N., Boman, K., Englund, A., Jensen, S. M., Kjellman, B., Tornvall, P., & Rosenqvist, M. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehp006 · Cited by 65 · see citing works
Use of Nonantiarrhythmic Drugs for Prevention of Sudden Cardiac Death
Alberte, C., & Zipes, D. P. (2003) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.14.s9.23.x · Cited by 63 · see citing works
Vrtovec, B., Okrajšek, R., Goličnik, A., Ferjan, M., Starc, V., Schlegel, T. T., & Radovančević, B. (2008) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2007.10.013 · Cited by 61 · see citing works
Congestive Heart Failure in Patients with Chronic Kidney Disease and on Dialysis
Schreiber, B. D. (2003) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200304000-00004 · Cited by 59 · see citing works
Frishman, W. H. (2007) · Yearbook of Medicine · doi:10.1016/s0084-3873(08)70234-7 · Cited by 55 · see citing works
Phillips, K. P. (2013) · Europe PMC (PubMed Central) · doi:10.4022/jafib.935 · Cited by 55 · see citing works
Macfarlane, P. W., & Norrie, J. D. (2006) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2006.05.003 · Cited by 51 · see citing works
Large-scale randomized evidence: trials and meta-analyses of trials
Baigent, C., Peto, R., Gray, R. G., Parish, S., & Collins, R. (2010) · Oxford University Press eBooks · doi:10.1093/med/9780199204854.003.020303_update_002 · Cited by 48 · see citing works
Atrial Fibrillation in End‐Stage Renal Disease
Korantzopoulos, P. G., Kokkoris, S., Liu, T., Protopsaltis, I. D., Li, G., & Goudevenos, J. A. (2007) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2007.00877.x · Cited by 43 · see citing works
Knopp, R. H., & on behalf of the ASPEN Study Group (2006) · Diabetes Care · doi:10.2337/dc06-1678 · Cited by 43 · see citing works
High-risk elderly patients PROSPER from cholesterol-lowering therapy
Collins, R., & Armitage, J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11650-3 · Cited by 42 · see citing works
Xia, W., YIN, Z., Li, J., Song, Y., & Qu, X.-F. (2009) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2009.02554.x · Cited by 39 · see citing works
[Better reporting of harms in randomized trials: an extension of the CONSORT statement].
Gøtzsche, P. C. (2005) · PubMed · Cited by 36 · see citing works
Atorvastatin in Patients With Type 2 Diabetes Mellitus Undergoing Hemodialysis
Wanner, C., Krane, V., & März, W. (2005) · ACC Current Journal Review · doi:10.1016/j.accreview.2005.09.027 · Cited by 35 · see citing works
Tsai, C., Lai, L., Hwang, J., Wang, Y., Chiang, F., & Lin, J.-L. (2008) · American Heart Journal · doi:10.1016/j.ahj.2008.01.028 · Cited by 34 · see citing works
McLean, D. S., Ravid, S., Blazing, M. A., Gersh, B. J., Shui, A. M., & Cannon, C. P. (2008) · American Heart Journal · doi:10.1016/j.ahj.2007.10.024 · Cited by 33 · see citing works
Makuuchi, H., Furuse, A., Endo, M., Nakamura, H., Daida, H., Watanabe, M., Ohashi, Y., Hosoda, Y., Hosoda, S., Yamaguchi, H., et al. (2005) · Circulation Journal · doi:10.1253/circj.69.636 · Cited by 32 · see citing works
Howard, W. J. (2007) · Yearbook of Medicine · doi:10.1016/s0084-3873(08)70305-5 · Cited by 24 · see citing works
Effect of Statins on Preventing Recurrence of Atrial Fibrillation After Electrical Cardioversion
García-Fernández, A., Marín, F. R., Mainar, L., Roldán, V., & Martı́nez, J. G. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.07.019 · Cited by 23 · see citing works
Hreybe, H., Bedi, M., Ezzeddine, R., Barrington, W., Jain, S. K., Ngwu, O., & Saba, S. (2005) · American Heart Journal · doi:10.1016/j.ahj.2005.07.019 · Cited by 20 · see citing works
Large-scale randomized evidence: trials and meta-analyses of trials
Baigent, C., Peto, R., Gray, R. G., Parish, S., & Collins, R. (2010) · Oxford University Press eBooks · doi:10.1093/med/9780199204854.003.020303 · Cited by 20 · see citing works
Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria
Asselbergs, F. W., Diercks, G. F. H., & Hillege, H. L. (2005) · ACC Current Journal Review · doi:10.1016/j.accreview.2005.02.027 · Cited by 18 · see citing works
Valsartan for Prevention of Recurrent Atrial Fibrillation
Brabham, W. W. (2010) · Yearbook of Cardiology · doi:10.1016/s0145-4145(10)79862-2 · Cited by 17 · see citing works
Colivicchi, F., Marco Tubaro, U., Mocini, D., Ebert, A. G., Strano, S., Melina, G., Uguccioni, M., & Santini, M. (2010) · Current Medical Research and Opinion · doi:10.1185/03007991003751496 · Cited by 15 · see citing works
(2009) · Clinical Governance An International Journal · doi:10.1108/cgij.2009.24814bae.005 · Cited by 15 · see citing works
Tamayo, E., Alonso, Ó., Álvarez, F. J., Castrodeza, J., Flórez, S., & Stefano, S. D. (2008) · Medicina Clínica · doi:10.1157/13121102 · Cited by 13 · see citing works
Kudaiberdieva, G., & Görenek, B. (2007) · Acute Cardiac Care · doi:10.1080/17482940600990285 · Cited by 11 · see citing works
Effect of Atorvastatin on the Recurrence Rates of Atrial Fibrillation After Electrical Cardioversion
Waldo, A. L. (2007) · Yearbook of Cardiology · doi:10.1016/s0145-4145(08)70281-8 · Cited by 8 · see citing works
Inflammatory Response to Drug-Eluting Stent Placement
Aggarwal, A. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.07.011 · Cited by 5 · see citing works
Rienstra, M., Hagens, V., Crijns, H. J. G. M., Gelder, I. C. V., & Invest, R. (2004) · University of Groningen research database (University of Groningen / Centre for Information Technology) · Cited by 4 · see citing works
Takeshita, S., Ishida, Y., Nishimura, H., Kuramoto, E., Saito, A., Fujii, E., Adachi, K., Matsuura, A., Kawata, M., Shiotani, H., et al. (2005) · Japanese Circulation Journal-english Edition · Cited by 1 · see citing works
Flagged first, then by citations
3 of the 93 references couldn’t be matched to a known paper.
Research works printed but not linked: 5
- and their joint influence on mortality: the Framingham Heart Study. Circulation 2003;107:2920-5.
- Schwartz GG, Olsson AG, Chaitman J, Golberger M, Szarek M, Saseila WJ. Effect of intensive statin treatment on the occurence of atrial fibrillation after acute coronary syndrome: an analysis of the MIRACL trial. Circulation 2004;110:740.
- Tamayo E, Alonso O, Alvarez FJ, Castrodeza J, Florez S, di Stefano S. [Effects of simvastatin on acute-phase protein levels after cardiac surgery.] Med Clin (Barc) 2008;130:773-5.
- GISSI Prevenzione Investigators (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico). Results of the low-dose (20 mg) pravastatin GISSI prevenzione trial in 4271 patients with recent myocardial infarction: do stopped trials contribute to overall knowledge? Ital Heart J 2000;1:810-20.
- MRC/BHF. Heart protection study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo- controlled trial. Lancet 2002;360:7-22.
Cited by
Sorted by citations
Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association
Benjamin, E. J., Blaha, M. J., Chiuve, S. E., Cushman, M., Das, S. R., Deo, R., de Ferranti, S. D., Floyd, J., Fornage, M., Gillespie, C., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000485 · Cited by 12,591 · see citing works
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J., Blomström-Lundqvist, C., Boriani, G., Castellá, M., Dan, G., Dilaveris, P. E., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 2,605 · see citing works
Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association
Virani, S. S., Alonso, A., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Delling, F. N., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000757 · Cited by 9,175 · see citing works
Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association
Benjamin, E. J., Muntner, P., Alonso, A., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Das, S. R., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000659 · Cited by 9,036 · see citing works
Heart disease and stroke statistics-2018 update: a report from the american heart association
Benjamin, E. J., Virani, S. S., Callaway, C. W., Chamberlain, A. M., Chang, A. R., Cheng, S., Chiuve, S. E., Cushman, M., Delling, F. N., Deo, R., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000558 · Cited by 7,146 · see citing works
Heart Disease and Stroke Statistics—2012 Update: A Report From the American Heart Association
Writing Group Members, Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., et al. (2012) · Circulation · doi:10.1161/cir.0b013e31823ac046 · Cited by 7,333 · see citing works
Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., Das, S. R., de Ferranti, S., Després, J.-P., Fullerton, H. J., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000350 · Cited by 6,596 · see citing works
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438 · see citing works
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418 · see citing works
Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Anderson, C. A. M., Arora, P., Avery, C. L., Baker-Smith, C. M., Beaton, A. Z., Boehme, A. K., Buxton, A. E., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001123 · Cited by 8,300 · see citing works
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Tsao, C. W., Aday, A. W., Almarzooq, Z. I., Alonso, A., Beaton, A. Z., Bittencourt, M. S., Boehme, A. K., Buxton, A. E., Carson, A. P., Commodore-Mensah, Y., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001052 · Cited by 5,987 · see citing works
Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., de Ferranti, S., Després, J.-P., Fullerton, H. J., Howard, V. J., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000152 · Cited by 5,797 · see citing works
Heart Disease and Stroke Statistics—2014 Update
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Blaha, M. J., Dai, S., Ford, E. S., Fox, C. S., Franco, S., et al. (2013) · Circulation · doi:10.1161/01.cir.0000441139.02102.80 · Cited by 5,207 · see citing works
Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., Fox, C. S., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31828124ad · Cited by 5,292 · see citing works
Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Cheng, S., Delling, F. N., et al. (2021) · Circulation · doi:10.1161/cir.0000000000000950 · Cited by 5,784 · see citing works
Mach, F., Baigent, C., Catapano, A. L., Koskinas, K. C., Casula, M., Badimon, L., Chapman, M. J., De Backer, G. G., Delgado, V., Ference, B. A., et al. (2019) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2019.08.014 · Cited by 4,854 · see citing works
Joglar, J. A., Chung, M. K., Armbruster, A. L., Benjamin, E. J., Chyou, J. Y., Cronin, E. M., Deswal, A. M., Eckhardt, L. L., Goldberger, Z. D., Gopinathannair, R., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001193 · Cited by 2,989 · see citing works
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403 · see citing works
2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation
Joglar, J. A., Chung, M. K., Armbruster, A. L., Benjamin, E. J., Chyou, J. Y., Cronin, E. M., Deswal, A., Eckhardt, L. L., Goldberger, Z. D., Gopinathannair, R., et al. (2024) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.08.017 · Cited by 933 · see citing works
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery
Hillis, L. D., Smith, P. K., Anderson, J. L., Bittl, J. A., Bridges, C. R., Byrne, J. G., Cigarroa, J. E., DiSesa, V. J., Hiratzka, L. F., Hutter, A. M., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.009 · Cited by 819 · see citing works
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery
Hillis, L. D., Smith, P. K., Anderson, J. L., Bittl, J. A., Bridges, C. R., Byrne, J. G., Cigarroa, J. E., DiSesa, V. J., Hiratzka, L. F., Hutter, A. M., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31823c074e · Cited by 782 · see citing works
Role of Inflammation in Atrial Fibrillation Pathophysiology and Management
Harada, M., Wagoner, D. R. V., & Nattel, S. (2015) · Circulation Journal · doi:10.1253/circj.cj-15-0138 · Cited by 474 · see citing works
Epidemiology and modifiable risk factors for atrial fibrillation
Elliott, A. D., Middeldorp, M. E., Gelder, I. C. V., Albert, C. M., & Sanders, P. (2023) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00820-8 · Cited by 380 · see citing works
Perioperative Rosuvastatin in Cardiac Surgery
Zheng, Z., Jayaram, R., Jiang, L., Emberson, J., Zhao, Y., Li, Q., Du, J., Guarguagli, S., Hill, M., Chen, Z., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1507750 · Cited by 322 · see citing works
Evaluating the Atrial Myopathy Underlying Atrial Fibrillation
Goldberger, J. J., Arora, R., Green, D., Greenland, P., Lee, D. C., Lloyd‐Jones, D. M., Markl, M., Ng, J., & Shah, S. J. (2015) · Circulation · doi:10.1161/circulationaha.115.016795 · Cited by 244 · see citing works
Oxidative stress in atrial fibrillation: An emerging role of NADPH oxidase
Youn, J.-Y., Zhang, J., Zhang, Y., Chen, H., Liu, D., Ping, P., Weiss, J. N., & Cai, H. “. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.04.019 · Cited by 216 · see citing works
The Increasing Role of Rhythm Control in Patients With Atrial Fibrillation
Camm, A. J., Naccarelli, G. V., Mittal, S., Crijns, H. J. G. M., Hohnloser, S. H., Ma, C., Natale, A., Turakhia, M. P., & Kirchhof, P. F. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.03.337 · Cited by 210 · see citing works
Alonso, A., Yin, X.-Y., Roetker, N. S., Magnani, J. W., Kronmal, R., Ellinor, P., Chen, L. Y., Lubitz, S., McClelland, R., Mcmanus, D. D., et al. (2014) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.114.001211 · Cited by 131 · see citing works
Macedo, A. F., Taylor, F. C., Casas, J. P., Adler, A. J., Prieto‐Merino, D., & Ebrahim, S. B. J. (2014) · BMC Medicine · doi:10.1186/1741-7015-12-51 · Cited by 183 · see citing works
Are cardiovascular risk factors also associated with the incidence of atrial fibrillation?
Allan, V., Honarbakhsh, S., Casas, J. P., Wallace, J., Hunter, R. J., SCHILLING, R. J., Perel, P., Morley, K. I., Banerjee, A., & Hemingway, H. (2017) · Thrombosis and Haemostasis · doi:10.1160/th16-11-0825 · Cited by 180 · see citing works
Christodoulides, S., Dimidi, E., Fragkos, K. C., Farmer, A. D., Whelan, K., & Scott, S. M. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13662 · Cited by 144 · see citing works
Menezes, A. R., Lavie, C. J., DiNicolantonio, J. J., O’Keefe, J. H., Morin, D. P., Khatib, S., & Milani, R. V. (2013) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2013.01.022 · Cited by 136 · see citing works
JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias
Ono, K., Iwasaki, Y., Akao, M., Ikeda, T., Ishii, K., Inden, Y., Kusano, K., Kobayashi, Y., Koretsune, Y., Sasano, T., et al. (2022) · Circulation Journal · doi:10.1253/circj.cj-20-1212 · Cited by 132 · see citing works
Görenek, B., Pelliccia, A., Benjamin, E. J., Boriani, G., Crijns, H. J. G. M., Fogel, R. I., Gelder, I. C. V., Halle, M., Kudaiberdieva, G., Lane, D. A., et al. (2016) · EP Europace · doi:10.1093/europace/euw242 · Cited by 128 · see citing works
Mach, F., Baigent, C., Catapano, A. L., Koskinas, K. C., Casula, M., Badimon, L., Chapman, M. J., De Backer, G. G., Delgado, V., Ference, B. A., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz455 · Cited by 8,961 · see citing works
Is Atrial Fibrillation a Preventable Disease?
Du, X., Dong, J., & Ma, C. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.02.020 · Cited by 116 · see citing works
Mariani, J. A., Doval, H. C., Nul, D. R., Varini, S. D., Grancelli, H., Ferrante, D., Tognoni, G., & Macchia, A. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.112.005033 · Cited by 107 · see citing works
Görenek, B., Pelliccia, A., Benjamin, E. J., Boriani, G., Crijns, H. J. G. M., Fogel, R. I., Gelder, I. C. V., Halle, M., Kudaiberdieva, G., Lane, D. A., et al. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487316676037 · Cited by 103 · see citing works
Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis
Copland, E., Canoy, D., Nazarzadeh, M., Bidel, Z., Ramakrishnan, R., Woodward, M., Chalmers, J. P., Teo, K. K., Pepine, C. J., Davis, B. R., et al. (2021) · The Lancet Oncology · doi:10.1016/s1470-2045(21)00033-4 · Cited by 101 · see citing works
Rahimi, K., Bhala, N. B., Kamphuisen, P. W., Emberson, J., Biere‐Rafi, S., Krane, V., Robertson, M., Wikstrand, J., & McMurray, J. J. V. (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001310 · Cited by 96 · see citing works
Pinho-Gomes, A. C., Reilly, S., Brandes, R. P., & Casadei, B. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5542 · Cited by 94 · see citing works
Patient Decision Aids for Colorectal Cancer Screening
Volk, R. J., Linder, S. K., Lopez-Olivo, M. A., Kamath, G. R., Reuland, D. S., Saraykar, S., Leal, V. B., & Pignone, M. P. (2016) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2016.06.022 · Cited by 83 · see citing works
Statins and the autonomic nervous system
Millar, P. J., & Floras, J. S. (2013) · Clinical Science · doi:10.1042/cs20130332 · Cited by 75 · see citing works
Pathak, R. K., Lau, D. H., Mahajan, R., & Sanders, P. (2013) · Europe PMC (PubMed Central) · doi:10.4022/jafib.986 · Cited by 78 · see citing works
Fichera, E., Gray, E., & Sutton, M. (2016) · Social Science & Medicine · doi:10.1016/j.socscimed.2016.05.005 · Cited by 66 · see citing works
Nattel, S., Sager, P. T., Hüser, J., Heijman, J., & Dobrev, D. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab093 · Cited by 63 · see citing works
Thomas, M., Wu, L., & Win, K. (2014) · Journal of Biomedical Research · doi:10.7555/jbr.28.20130191 · Cited by 65 · see citing works
Emdin, C. A., Callender, T., Cao, J., & Rahimi, K. (2015) · EP Europace · doi:10.1093/europace/euv021 · Cited by 55 · see citing works
Xia, J., Liyun, S., Lifang, Z., & Xu, F. (2014) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20140702 · Cited by 53 · see citing works
Rahimi, K., Majoni, W., Merhi, A., & Emberson, J. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs005 · Cited by 50 · see citing works
Hoffman, A. S., Lowenstein, L. M., Kamath, G. R., Housten, A. J., Leal, V. B., Linder, S. K., Jibaja‐Weiss, M. L., Raju, G. S., & Volk, R. J. (2016) · Cancer · doi:10.1002/cncr.30489 · Cited by 49 · see citing works
Atherosclerosis and atrial fibrillation – Two closely intertwined diseases
Willeit, K., & Kiechl, S. J. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2013.11.082 · Cited by 45 · see citing works
JCS / JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias
Ono, K., Iwasaki, Y., Akao, M., Ikeda, T., Ishii, K., Inden, Y., Kusano, K., Kobayashi, Y., Koretsune, Y., Sasano, T., et al. (2022) · Journal of Arrhythmia · doi:10.1002/joa3.12714 · Cited by 41 · see citing works
Mourtzinis, G., Kahan, T., Boström, K. B., Schiöler, L., Wallin, L. C., Hjerpe, P., Hasselström, J., & Manhem, K. (2018) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2018.03.024 · Cited by 40 · see citing works
Pharmacological strategies for prevention of postoperative atrial fibrillation
Turagam, M. K., Downey, F. X., Kress, D. C., Sra, J. S., Tajik, A. J., & Jahangir, A. (2015) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2015.1018182 · Cited by 39 · see citing works
Yao, Y., Liu, F., Wang, Y., & Liu, Z. (2020) · Clinical Cardiology · doi:10.1002/clc.23430 · Cited by 37 · see citing works
Educational inequalities in smoking over the life cycle: an analysis by cohort and gender
Bricard, D., Jusot, F., Beck, F., Khlat, M., & Legleye, S. (2015) · International Journal of Public Health · doi:10.1007/s00038-015-0731-6 · Cited by 38 · see citing works
Endothelial function and atrial fibrillation: A missing piece of the puzzle?
Black, N., Mohammad, F., Saraf, K., & Morris, G. M. (2021) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.15277 · Cited by 36 · see citing works
Bang, C. N., Greve, A. M., Abdulla, J., Køber, L., Gislason, G., & Wachtell, K. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.08.056 · Cited by 34 · see citing works
SIMANTIRAKIS, E. N., Papakonstantinou, P. Ε., KANOUPAKIS, E. M., CHLOUVERAKIS, G. I., Tzeis, S. E., & Vardas, P. E. (2018) · Clinical Cardiology · doi:10.1002/clc.22904 · Cited by 32 · see citing works
Loffredo, L., Angelico, F., Perri, L., & Violi, F. (2012) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-12-107 · Cited by 31 · see citing works
Atrial fibrosis and substrate based characterization in atrial fibrillation: Time to move forwards
Quah, J. X., Dharmaprani, D., Tiver, K. D., Lahiri, A., Hecker, T., Perry, R., Selvanayagam, J. B., Joseph, M. X., McGavigan, A. D., & Ganesan, A. N. (2021) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.14987 · Cited by 32 · see citing works
Patti, G., Bennett, R., Seshasai, S. R. K., Cannon, C. P., Cavallari, I., Chello, M., Nusca, A., Mega, S., Caorsi, C., Spadaccio, C., et al. (2015) · EP Europace · doi:10.1093/europace/euv001 · Cited by 30 · see citing works
Atrial fibrillation in the cardiometabolic patient
Sensi, F. D., Costantino, S., Limbruno, U., & Paneni, F. (2019) · Minerva Medica · doi:10.23736/s0026-4806.18.05882-2 · Cited by 29 · see citing works
Menstrual Leave: Good Intention, Poor Solution
King, S. (2020) · Aligning perspectives on health, safety and well-being · doi:10.1007/978-3-030-53269-7_9 · Cited by 29 · see citing works
Warita, S., Kawasaki, M., Tanaka, R., Ono, K., Kojima, T., Hirose, T., Iwama, M., Watanabe, T., Nishigaki, K., Takemura, G., et al. (2012) · Circulation Journal · doi:10.1253/circj.cj-12-0722 · Cited by 29 · see citing works
The role of inflammation in the pathogenesis and treatment of arrhythmias
Armbruster, A. L., Campbell, K. B., Kahanda, M. G., & Cuculich, P. S. (2022) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.2663 · Cited by 28 · see citing works
Cho, K. I., Kim, B., Cha, T., Heo, J. H., Kim, H.-S., & Lee, J. (2014) · Heart and Vessels · doi:10.1007/s00380-014-0505-8 · Cited by 28 · see citing works
Fecal Carriage of Staphylococcus aureus in the Hospital and Community Setting: A Systematic Review
Claassen-Weitz, S., Shittu, A. O., Ngwarai, M. R., Thabane, L., Nicol, M. P., & Kaba, M. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00449 · Cited by 28 · see citing works
Hindricks, G., Potpara, T. S., Dagres, N., Arbelo, E., Bax, J. J., Blomström-Lundqvist, C., Boriani, G., Castellá, M., Dan, G., Dilaveris, P. E., et al. (2021) · Revista Española de Cardiología · doi:10.1016/j.recesp.2020.10.022 · Cited by 24 · see citing works
Statins in heart failure: do we need another trial?
Kadirvelu, A., Osei, & Reidpath, D. D. (2013) · Vascular Health and Risk Management · doi:10.2147/vhrm.s44499 · Cited by 27 · see citing works
Trohman, R. G., Huang, H. D., & Sharma, P. S. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1060030 · Cited by 28 · see citing works
Cardiometabolic Risk Factors and Atrial Fibrillation
Menezes, A. R., Lavie, C. J., DiNicolantonio, J. J., O’Keefe, J. H., Morin, D. P., Khatib, S., Messerli, F. H., & Milani, R. V. (2013) · Reviews in Cardiovascular Medicine · doi:10.3909/ricm0693 · Cited by 25 · see citing works
Kwok, J. M. F., Ma, C. C.-H., & Ma, S. (2012) · Vascular Pharmacology · doi:10.1016/j.vph.2012.10.003 · Cited by 24 · see citing works
Cheng, J. (2014) · Medical Science Monitor · doi:10.12659/msm.891049 · Cited by 23 · see citing works
Bang, C. N., Gislason, G., Greve, A. M., Torp-Pedersen, C. T., Køber, L., & Wachtell, K. (2012) · European Journal of Preventive Cardiology · doi:10.1177/2047487312462804 · Cited by 23 · see citing works
Watanabe, T., Kawasaki, M., Tanaka, R., Ono, K., Nishigaki, K., Takemura, G., Arai, M., Noda, T., Watanabe, S., & Minatoguchi, S. (2013) · Hypertension Research · doi:10.1038/hr.2013.25 · Cited by 22 · see citing works
Rutishauser, J. (2011) · Swiss Medical Weekly · doi:10.4414/smw.2011.13310 · Cited by 22 · see citing works
McManus, D. D., Saczynski, J. S., Ward, J. A., Jaggi, K., Bourell, P., Darling, C. E., & Goldberg, R. J. (2012) · Europe PMC (PubMed Central) · doi:10.4022/jafib.442 · Cited by 22 · see citing works
Bang, C. N., Greve, A. M., Boman, K., Egstrup, K., Gohlke-Baerwolf, C., Køber, L., Nienaber, C. A., Ray, S. G., Rossebø, A. B., & Wachtell, K. (2012) · American Heart Journal · doi:10.1016/j.ahj.2012.01.026 · Cited by 22 · see citing works
Ethical issues with colorectal cancer screening—a systematic review
Hofmann, B. (2016) · Journal of Evaluation in Clinical Practice · doi:10.1111/jep.12690 · Cited by 20 · see citing works
MicroRNAs in Atrial Fibrillation: Mechanisms, Vascular Implications, and Therapeutic Potential
Vardas, E. P., Theofilis, P., Oikonomou, E. K., Vardas, P. E., & Tousoulis, D. (2024) · Biomedicines · doi:10.3390/biomedicines12040811 · Cited by 20 · see citing works
Upstream Therapy for Atrial Fibrillation Prevention: The Role of Sacubitril/Valsartan
Vecchis, R. D., Paccone, A., & Maio, M. D. (2020) · Cardiology Research · doi:10.14740/cr1073 · Cited by 20 · see citing works
Emphasizing Statin Safety in the Hospitalized Patient: A Review
Leung, A., Schaefer, É., Tempelhof, M. W., & Stone, N. J. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2012.02.022 · Cited by 18 · see citing works
Zhou, X. P., Du, J., Yuan, J., & Chen, Y. (2013) · International Journal of Medical Sciences · doi:10.7150/ijms.5248 · Cited by 18 · see citing works
Statin Use and Risk of Atrial Fibrillation or Flutter
Veronese, G., Montomoli, J., Schmidt, M., Horváth–Puhó, E., & Sørensen, H. T. (2013) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e31827ab488 · Cited by 18 · see citing works
Formalizing the definition of meta‐analysis in Molecular Ecology
ArchMiller, A. A., Bauer, E. F., Koch, R. E., Wijayawardena, B. K., Anil, A., Kottwitz, J. J., Munsterman, A. S., & Wilson, A. E. (2015) · Molecular Ecology · doi:10.1111/mec.13264 · Cited by 17 · see citing works
Tsujino, Y., Sakamoto, T., Kinoshita, K., Nakatani, Y., Yamaguchi, Y., Kataoka, N., Nishida, K., & Kinugawa, K. (2019) · Heart and Vessels · doi:10.1007/s00380-019-01377-2 · Cited by 17 · see citing works
Alves‐Cabratosa, L., García-Gil, M., Comas‐Cufí, M., Ponjoan, A., Martí‐Lluch, R., Parramon, D., Blanch, J., Elosua-Bayés, M., & Ramos, R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186972 · Cited by 15 · see citing works
A Potential Role of Esophageal Cancer Related Gene-4 for Atrial Fibrillation
Huang, L., Yu, H., Fan, X., Li, X., Mao, L., Cheng, J., Zeng, X., & Dang, X. (2017) · Scientific Reports · doi:10.1038/s41598-017-02902-x · Cited by 15 · see citing works
Kumagai, N., Nusser, J. A., Inoue, H., Okumura, K., Yamashita, T., Kubo, T., Kitaoka, H., Origasa, H., & Atarashi, H. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.04.011 · Cited by 14 · see citing works
Li, L., Wang, C., Ye, Z., Spall, H. G. C. V., Zhang, J., Lip, G. Y. H., & Li, G. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.033840 · Cited by 13 · see citing works
Liu, T., Korantzopoulos, P. G., Li, L., & Li, G. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.11.084 · Cited by 13 · see citing works
Statins reduce new-onset atrial fibrillation after acute myocardial infarction
Tseng, C.-H., Chung, W.-J., Li, C.-Y., Tsai, T., Lee, C., Hsueh, S., Wu, C., & Cheng, C. (2020) · Medicine · doi:10.1097/md.0000000000018517 · Cited by 13 · see citing works
Usefulness of ultrasound in sub-Saharan patients with a serological diagnosis of schistosomiasis
Castillo-Fernández, N., Soriano-Pérez, M. J., Lozano-Serrano, A. B., Sánchez-Sánchez, J. C., Villarejo-Ordóñez, A., Cuenca-Gómez, J. Á., Vázquez-Villegas, J., Cabeza-Barrera, M. I., & Salas-Coronas, J. (2021) · Infection · doi:10.1007/s15010-021-01612-x · Cited by 12 · see citing works
Han, X., Liu, Y., Li, G., Tse, G., & Liu, T. (2023) · Heart and Mind · doi:10.4103/hm.hm-d-23-00028 · Cited by 11 · see citing works
Hillis, L. D., Smith, P. K., Anderson, J. L., Bittl, J. A., Bridges, C. R., Byrne, J. G., Cigarroa, J. E., DiSesa, V. J., Hiratzka, L. F., Hutter, A. M., et al. (2011) · Cited by 11 · see citing works
Rahimi, K., Patel, A. A., & MacMahon, S. W. (2012) · PubMed · Cited by 11 · see citing works
Qi, W., Liu, T., Xu, G., Li, L., Liang, Y., Ye, L., & Li, G. (2015) · Trials · doi:10.1186/s13063-015-0836-5 · Cited by 10 · see citing works
Blood Pressure Lowering and Risk of Cancer
Nazarzadeh, M., Copland, E., Smith-Byrne, K., Canoy, D., Bidel, Z., Woodward, M., Yang, Q., McKay, J., Mälarstig, A., Hedman, Å. K., et al. (2025) · JACC CardioOncology · doi:10.1016/j.jaccao.2025.03.005 · Cited by 9 · see citing works
- Authors
- Rahimi, K., Emberson, J., McGale, P., Majoni, W., Merhi, A., Asselbergs, F. W., Krane, V., Macfarlane, P. W., & Executive, P. I. A. O. B. O. T. P.
- Affiliations
- University of Oxford (GB)
- Royal Darwin Hospital (AU)
- University Medical Center Utrecht (NL)
- University of Würzburg (DE)
- Corresponding author
- Rahimi, K.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2011-03-16
- Volume
- 342
- Issue
- mar16 2
- Pages
- d1250-d1250
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2145838023
- Cited by
- 159
- References
- 93
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 9 · 2023: 6 · 2022: 5 · 2021: 10 · 2020: 12 · 2019: 6 · 2018: 6 · 2017: 8 · 2016: 14 · 2015: 12 · 2014: 11 · 2013: 19 · 2012: 23
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- British Heart Foundation (RE/08/004)
- ZonMw (90700342, ZonMw grant 90700342)
- BHF Centre of Research Excellence, Oxford (RE/08/004)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Keywords
- statins, atrial fibrillation, statin dose, unpublished data, trial heterogeneity, cardiovascular risk reduction, statin trials
- MeSH terms
- Anti-Arrhythmia Agents, Atrial Fibrillation, Humans, Risk Factors, Randomized Controlled Trials as Topic, Treatment Outcome, Publication Bias, Hydroxymethylglutaryl-CoA Reductase Inhibitors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
