Sexual and physical abuse are not associated with rectal hypersensitivity in patients with irritable bowel syndrome
Open accessAbstract
Background: Patients with irritable bowel syndrome (IBS) have reduced pain thresholds for rectal distension. In addition, the prevalence of sexual/physical abuse in referred IBS patients is high and is associated with greater pain reporting, poorer health status, and poorer outcome. This lead to a hypothesis that abuse history may sensitise patients to report pain at a lower threshold. Aim: To compare rectal pain thresholds in women with IBS who had a history of severe abuse to IBS women with no history of abuse. Methods: We studied 74 IBS patients with a history of severe physical and/or sexual abuse and 85 patients with no history of abuse. Abuse history was assessed by a previously validated self-report abuse screening questionnaire. Rectal sensory thresholds were assessed using an electronic barostat and determined by the ascending method of limit (AML) and by the tracking technique. Results: IBS patients with a history of severe abuse had significantly higher rectal pain thresholds, as measured by AML (F (1, 111) = 6.06; p = 0.015) and the tracking technique (F (1, 109) = 5.21; p = 0.024). Patients with a history of severe abuse also reported a significantly higher threshold for urgency to defecate (F (1, 113) = 11.23; p = .001). Conclusion: Severe sexual/physical abuse is associated with higher urge and pain thresholds for rectal distension in IBS patients. This suggests that the greater pain reporting and poorer health status in IBS patients with abuse history are not related to increased rectal pain sensitivity. Further studies are needed to determine the causes of these findings.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The findings are consistent with reports that women experiencing violence have adverse health outcomes and with other systematic reviews associating pain symptoms or syndromes with some type of adult or childhood abuse.
“Our findings are consistent with reports that women experiencing violence have adverse health outcomes [18–21], and with other systematic reviews that associate some pain symptoms/syndromes with some type of adult or childhood abuse [30–34].”
From The association between violence against women and chronic pain: a systematic review and meta-analysis (2024) · cites this paper as [20]
The introduction reports prior findings associating abuse history with greater pain reporting and poorer health in patients with IBS. But this paper is an original study, not a systematic review, and its Discussion says its own groups did not differ in clinical symptom ratings. It therefore supports the general association as background, not the claim that this cited work is a systematic review establishing it. (LLM, conf=0.87)
Experimental — accuracy not yet measuredThe most common diagnoses in victimized individuals are pelvic pain, fibromyalgia, irritable bowel syndrome/bowel symptoms, abdominal pain, migraine/headache, back pain, chest pain, and neck pain, which tend to become chronic.
“The most common diagnosis of victimized are pelvic pain [13], fibromyalgia [14], irritable bowel syndrome/bowel symptoms [15], abdominal pain [16], migraine/headache [17], back pain [18], chest pain [19], and neck pain [20], which tend to become chronic as well as the pain derived from them.”
From The Risk Factors of Chronic Pain in Victims of Violence: A Scoping Review (2023) · cites this paper as [15]
Physical and psychological stress, cognition, and early life experience can affect intestinal sensory perception.
“For example, it has been shown that physical and psychological stress (112), cognition (e.g., attention vs. distraction to aversive stimulus) (55), and early life experience (e.g., sexual and physical abuse) (39, 149) can affect intestinal sensory perception.”
From Intestinal microbiota and immune function in the pathogenesis of irritable bowel syndrome (2013) · cites this paper as [149]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
AGA technical review on irritable bowel syndrome.
Drossman, D. A., Camilleri, M., Mayer, E. A., & Whitehead, W. E. (2002) · Gastroenterology · doi:10.1053/gast.2002.37095 · Cited by 1,384 · see citing works
Self-citationBremner, J. D., Randall, P., Vermetten, E., Staib, L., Bronen, R. A., Mazure, C., Capelli, S., McCarthy, G., Innis, R. B., & Charney, D. S. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(96)00162-x · Cited by 1,283 · see citing works
Altered rectal perception is a biological marker of patients with irritable bowel syndrome
Mertz, H., Naliboff, B. D., Munakata, J., Niazi, N., & Mayer, E. A. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90267-8 · Cited by 976 · see citing works
Hippocampal volume in women victimized by childhood sexual abuse
STEIN, M. B., KOVEROLA, C., HANNA, C., TORCHIA, M. G., & McCLARTY, B. (1997) · Psychological Medicine · doi:10.1017/s0033291797005242 · Cited by 924 · see citing works
Basic and clinical aspects of visceral hyperalgesia
Mayer, E. A., & Gebhart, G. F. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90086-8 · Cited by 920 · see citing works
Psychosocial Aspects of the Functional Gastrointestinal Disorders
Levy, R. L., Olden, K. W., Naliboff, B. D., Bradley, L. A., Francisconi, C., Drossman, D. A., & Creed, F. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.057 · Cited by 776 · see citing works
Self-citationDrossman, D. A. (1994) · Medical Entomology and Zoology · Cited by 470 · see citing works
Self-citationSexual and Physical Abuse and Gastrointestinal Illness: Review and Recommendations
Drossman, D. A., Talley, N. J., Leserman, J., Olden, K. W., & Barreiro, M. A. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-10-199511150-00007 · Cited by 445 · see citing works
Self-citationProgression of fibrosis in chronic hepatitis C
Ghany, M. G., Kleiner, D. E., Alter, H. J., Doo, E. C., Khokar, F., Promrat, K., Herion, D. W., Park, Y., Liang, T. J., & Hoofnagle, J. H. (2003) · Gastroenterology · doi:10.1053/gast.2003.50018 · Cited by 402 · see citing works
Whitehead, W. E., & Delvaux, M. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018885028501 · Cited by 387 · see citing works
Self-citationWHITEHEAD, W., & PALSSON, O. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70099-x · Cited by 314 · see citing works
Self-citationPsychosocial aspects of the functional gastrointestinal disorders
Drossman, D. A., Creed, F. H., Olden, K. W., Svedlund, J., Toner, B. B., & Whitehead, W. E. (1999) · Gut · doi:10.1136/gut.45.2008.ii25 · Cited by 308 · see citing works
Self-citationRole of visceral afferent mechanisms in functional bowel disorders
Mayer, E. A., & Raybould, H. E. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90475-g · Cited by 298 · see citing works
Koloski, N. A., Talley, N. J., & Boyce, P. M. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03789.x · Cited by 253 · see citing works
Health status by gastrointestinal diagnosis and abuse history
Drossman, D., Li, Z., Leserman, J., Toomey, T., & Hu, Y. (1996) · Gastroenterology · doi:10.1053/gast.1996.v110.pm8613034 · Cited by 235 · see citing works
Self-citationPsychosocial aspects of the functional gastrointestinal disorders
Drossman, D. A. (1996) · De Gruyter eBooks · doi:10.1515/9783110815542-005 · Cited by 194 · see citing works
Self-citationWalker, E. A., Gelfand, A. N., Gelfand, M. D., & Katon, W. J. (1995) · Psychological Medicine · doi:10.1017/s0033291700033225 · Cited by 181 · see citing works
Drossman, D. A., Ringel, Y., Vogt, B. A., Leserman, J., Lin, W., Smith, J. K., & Whitehead, W. E. (2003) · Gastroenterology · doi:10.1053/gast.2003.50103 · Cited by 170 · see citing works
Self-citationDo psychosocial factors define symptom severity and patient status in irritable bowel syndrome?
Drossman, D. A. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00081-9 · Cited by 168 · see citing works
Self-citationSexual and Physical Abuse and Gastrointestinal Illness
Drossman, D. A. (1995) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529509107768 · Cited by 168 · see citing works
Self-citationDrossman, D. A., Li, Z., Toner, B. B., Diamant, N. E., Creed, F. H., Thompson, D. G., Read, N. W., Babbs, C., Barreiro, M. A., Bank, L., et al. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02064187 · Cited by 165 · see citing works
Self-citationTalley, N. J., Fett, S. L., & Zinsmeister, A. R. (1995) · PubMed · Cited by 152 · see citing works
What determines severity among patients with painful functional bowel disorders?
Drossman, D. A., Whitehead, W. E., Toner, B. B., Diamant, N. E., Hu, Y., Bangdiwala, S. I., & Jia, H. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01936.x · Cited by 152 · see citing works
Self-citationLeserman, J., Li, Z., Drossman, D. A., Toomey, T. C., Nachman, G., & Glogau, L. (1997) · Psychosomatic Medicine · doi:10.1097/00006842-199703000-00007 · Cited by 135 · see citing works
Self-citationRingel, Y., Sperber, A. D., & Drossman, D. A. (2001) · Annual Review of Medicine · doi:10.1146/annurev.med.52.1.319 · Cited by 117 · see citing works
Self-citationAnismus as a marker of sexual abuse
Leroi, A., Berkelmans, I., Denis, P., Hémond, M., & Devroede, G. J. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02285184 · Cited by 115 · see citing works
Pain from Rectal Distension in Women with Irritable Bowel Syndrome (Relationship to Sexual Abuse)
Whitehead, W. E., Crowell, M. D., Davidoff, A. L., Palsson, O. S., & Schuster, M. M. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018820315549 · Cited by 110 · see citing works
Self-citationRingel, Y., Drossman, D. A., Turkington, T. G., Bradshaw, B. H., Hawk, T. C., Bangdiwala, S. I., Coleman, R. E., & Whitehead, W. E. (2003) · Digestive Diseases and Sciences · doi:10.1023/a:1025455330704 · Cited by 84 · see citing works
Self-citationIrritable bowel syndrome and sexual/physical abuse history
Drossman, D. A. (1997) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-199704000-00002 · Cited by 73 · see citing works
Self-citationSemple, W. E., Goyer, P. F., McCormick, R., Morris, E. D., Compton-Toth, B. A., Muswick, G. J., Nelson, D. P., Donovan, B. S., Leisure, G., Berridge, M. S., et al. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90264-e · Cited by 60 · see citing works
Modulation of antigen trafficking to MHC class II–positive late endosomes of enterocytes
Zimmer, K., Büning, J., Weber, P., Kaiserlian, D., & Ströbel, S. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)70421-5 · Cited by 56 · see citing works
Physical Symptoms, Somatization, and Dissociation in Women Survivors of Childhood Sexual Assault
Farley, M., & Keaney, J. C. (1997) · Women & Health · doi:10.1300/j013v25n03_03 · Cited by 55 · see citing works
Devroede, G. J. (2000) · Progress in brain research · doi:10.1016/s0079-6123(08)62135-4 · Cited by 25 · see citing works
Sexual and physical abuse and gastrointestinal illness
Drossman, D. A., Talley, N. J., Leserman, J., Olden, K. W., & Barreiro, M. A. (1996) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-199601000-00025 · Cited by 20 · see citing works
Self-citationHealth status by gastrointestinal diagnosis and abuse history
Drossman, D. A., Li, Z., Leserman, J., Toomey, T. C., & Hu, Y. (1996) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-199606000-00022 · Cited by 16 · see citing works
Self-citationWootton, J. C. (2000) · Journal of Women s Health & Gender-Based Medicine · doi:10.1089/15246090050147772 · Cited by 16 · see citing works
Visceral Hyperalgesia: The Key for Unraveling Functional Gastrointestinal Disorders
Rao, S. S. C. (2008) · Digestive Diseases · doi:10.1159/000171558 · Cited by 13 · see citing works
Association of anterior cingulate cortex (ACC) activation with psychoscial distress and pain reports
Ringel, Y., Drossman, D. A., Leserman, J., Lin, W., Liu, H., Vogt, B. A., & Whitehead, W. E. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)80477-8 · Cited by 10 · see citing works
Self-citationRingel, Y., Drossman, D. A., Leserman, J., Lin, W., Liu, H., Vogt, B. A., & Whitehead, W. E. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)82688-4 · Cited by 10 · see citing works
Self-citationWhitehead, W. E., Drossman, D. A., Diamant, N. E., Toner, B. B., Bangdiwala, S. I., Hu, Y., Bradshaw, B. H., Leutri, F., Mikula, K., & Jia, H. (2000) · Gastroenterology · doi:10.1016/s0016-5085(00)82590-1 · Cited by 5 · see citing works
Self-citation
Flagged first, then by citations
1 of the 41 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Drossman DA. Do psychosocial factors define symptom severity and patient status? Am J Med 1999;107:41S-50.
- Ringel Y, Drossman DA, Liu H, et al. Anterior shift of cingulate activity with painful rectal distension in subjects with sexual/physical abuse. Gastroenterology 2002;122:A311.
- Ringel Y, Drossman DA, Liu H, et al. fMRI of cingulate activation to painful rectal distension in IBS and sexual/physical abuse. Gastroenterology 2002;122:A311.
Cited by
Sorted by citations
Fibromyalgia and overlapping disorders: The unifying concept of central sensitivity syndromes
Yunus, M. B. (2007) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2006.12.009 · Cited by 780 · see citing works
Diagnosis and Treatment of Dyssynergic Defecation
Rao, S. S. C., & Patcharatrakul, T. (2016) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm16060 · Cited by 285 · see citing works
Camilleri, M., McKinzie, S., Busciglio, I. A., Low, P. A., Sweetser, S. R., Burton, D. D., Baxter, K. L., Ryks, M. D., & Zinsmeister, A. R. (2008) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.02.060 · Cited by 242 · see citing works
Dyssynergic Defecation and Biofeedback Therapy
Rao, S. S. C. (2008) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2008.06.011 · Cited by 231 · see citing works
Irritable bowel syndrome: Diagnosis and pathogenesis
El‐Salhy, M. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i37.5151 · Cited by 214 · see citing works
PTSD and stress sensitisation: A tale of brain and body
Stam, R. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.11.010 · Cited by 211 · see citing works
The Physiology of Human Defecation
Palit, S., Lunniss, P. J., & Scott, S. M. (2012) · Digestive Diseases and Sciences · doi:10.1007/s10620-012-2071-1 · Cited by 193 · see citing works
Peripheral and central mechanisms of visceral sensitization in man
Anand, P., Aziz, Q., Willert, R. P., & Oudenhove, L. V. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2006.00873.x · Cited by 183 · see citing works
Ringel, Y., Drossman, D. A., Leserman, J., Suyenobu, B. Y., Wilber, K. P., Lin, W., Whitehead, W. E., Naliboff, B. D., Berman, S. M., & Mayer, E. A. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.11.011 · Cited by 156 · see citing works
Self-citationFunctional Abdominal Pain Syndrome
Clouse, R. E., Mayer, E. A., Aziz, Q., Drossman, D. A., Dumitrascu, D. L., Mönnikes, H., & Naliboff, B. D. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.062 · Cited by 158 · see citing works
Self-citationNew insights into the pathogenesis and pathophysiology of irritable bowel syndrome
Öhman, L., & Simrén, M. (2007) · Digestive and Liver Disease · doi:10.1016/j.dld.2006.10.014 · Cited by 155 · see citing works
Relationship of Abuse History to Functional Gastrointestinal Disorders and Symptoms
Leserman, J., & Drossman, D. A. (2007) · Trauma Violence & Abuse · doi:10.1177/1524838007303240 · Cited by 149 · see citing works
Self-citationGladman, M. A., Lunniss, P. J., Scott, S. M., & Swash, M. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00604.x · Cited by 144 · see citing works
Saito, Y. A. (2011) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2010.12.011 · Cited by 138 · see citing works
Ng, Q. X., Soh, A. Y. S., Loke, W., Venkatanarayanan, N., Lim, D. Y., & Yeo, W. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14446 · Cited by 134 · see citing works
Intestinal microbiota and immune function in the pathogenesis of irritable bowel syndrome
Ringel, Y., & Maharshak, N. (2013) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00207.2012 · Cited by 115 · see citing works
Self-citationNew Insights into the Pathogenesis and Pathophysiology of Irritable Bowel Syndrome
Collins, S. M. (1992) · Springer eBooks · doi:10.1007/978-1-4615-3314-6_9 · Cited by 115 · see citing works
Palsson, O. S., & Drossman, D. A. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.004 · Cited by 99 · see citing works
Self-citationNELSON, S., Baldwin, N., & Taylor, J. (2011) · Journal of Psychiatric and Mental Health Nursing · doi:10.1111/j.1365-2850.2011.01772.x · Cited by 97 · see citing works
Talley, N. J. (2006) · Internal Medicine Journal · doi:10.1111/j.1445-5994.2006.01217.x · Cited by 86 · see citing works
Functional findings in irritable bowel syndrome
Posserud, I. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i18.2830 · Cited by 83 · see citing works
Burgell, R., & Scott, S. (2012) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2012.18.4.373 · Cited by 172 · see citing works
Drossman, D. A. (2005) · Gut · doi:10.1136/gut.2004.058446 · Cited by 76 · see citing works
Self-citationRectal sensorimotor dysfunction in constipation
Scott, S. M., van den Berg, M. M., & Benninga, M. A. (2011) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2011.01.001 · Cited by 70 · see citing works
Functional abdominal pain syndrome
DROSSMAN, D. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00118-1 · Cited by 67 · see citing works
Self-citationInfluence of abuse history on gastric sensorimotor function in functional dyspepsia
Geeraerts, B., Oudenhove, L. V., Fischler, B., Vandenberghe, J. U., Caenepeel, P., Janssens, J., & Tack, J. F. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01178.x · Cited by 66 · see citing works
Oudenhove, L. V., Vandenberghe, J. U., Vos, R. D., Fischler, B., Demyttenaere, K., & Tack, J. F. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31822f32bf · Cited by 64 · see citing works
Liu, Y., Liu, L., Yang, Y., He, Y., Zhang, Y., Wang, M., Chen, S., & Yao, S. (2014) · Gastroenterology Research and Practice · doi:10.1155/2014/124261 · Cited by 60 · see citing works
Arebi, N., Gurmany, S., Bullas, D. C., Hobson, A. R., Stagg, A. J., & Kamm, M. A. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03801.x · Cited by 53 · see citing works
Quigley, E. M. M. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.010 · Cited by 51 · see citing works
Chronic Functional Abdominal Pain
Scanlon, S. A., Grover, M., Foxx–Orenstein, A. E., & Drossman, D. A. (2010) · doi:10.1002/9781444328417.ch62 · Cited by 51 · see citing works
Self-citationTraditional Thoughts on the Pathophysiology of Irritable Bowel Syndrome
Hasler, W. L. (2011) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2010.12.004 · Cited by 46 · see citing works
Cohen, H., Jotkowitz, A., Buskila, D., Pelles-Avraham, S., Kaplan, Z., Neumann, L., & Sperber, A. D. (2006) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2006.07.011 · Cited by 46 · see citing works
Oudenhove, L. V., & Aziz, Q. (2009) · Digestive and Liver Disease · doi:10.1016/j.dld.2009.07.004 · Cited by 37 · see citing works
Grinsvall, C., Törnblom, H., Tack, J., Oudenhove, L. V., & Simrén, M. (2018) · United European Gastroenterology journal · doi:10.1177/2050640617715851 · Cited by 32 · see citing works
Haskell, S. G., Papas, R. K., Heapy, A. A., Reid, M. C., & Kerns, R. D. (2008) · Pain Medicine · doi:10.1111/j.1526-4637.2008.00460.x · Cited by 32 · see citing works
Uvelli, A., Ribaudo, C., Gualtieri, G., Coluccia, A., & Ferretti, F. (2024) · BMC Women's Health · doi:10.1186/s12905-024-03097-w · Cited by 31 · see citing works
“Most studies focus on pelvic/vaginal pain [18], fibromy-algia [19], irritable bowel syndrome/bowel symptoms [20], abdominal pain [21], temporomandibular pain [22], breast pain [23], migraine/headache [24], back pain [25], and neck pain [26], which tend to become chronic as well as the pain derived…”
BackgroundCentral sensitivity syndromes: An overview
Yunus, M. B. (2009) · Journal of Musculoskeletal Pain · doi:10.3109/10582450903284752 · Cited by 29 · see citing works
Early Life Stress and Pain: An Important Link to Functional Bowel Disorders
Miranda, A. (2009) · Pediatric Annals · doi:10.3928/00904481-20090501-09 · Cited by 26 · see citing works
Pierce, J. M., Harte, S. E., Afari, N., Bradley, C. S., Griffith, J. W., Kim, J., Lutgendorf, S. K., Naliboff, B. D., Rodríguez, L. V., Taple, B. J., et al. (2023) · Pain · doi:10.1097/j.pain.0000000000002895 · Cited by 21 · see citing works
Lee, T., Lee, J., Hong, S., Jeon, S., Kwon, S., Kim, W., Kim, H. G., Cho, W., Cho, J., Kim, J.-O., et al. (2012) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2013.28.1.54 · Cited by 17 · see citing works
New Directions in Brain Imaging Research in Functional Gastrointestinal Disorders
Ringel, Y. (2006) · Digestive Diseases · doi:10.1159/000092881 · Cited by 19 · see citing works
Self-citationPierce, J. M., Hassett, A. L., Brummett, C. M., McAfee, J., Sieberg, C. B., Schrepf, A., & Harte, S. E. (2020) · Annals of Behavioral Medicine · doi:10.1093/abm/kaaa105 · Cited by 18 · see citing works
Rao, S. S. C., Yan, Y., Erdoğan, A., Coss‐Adame, E., Patcharatrakul, T., Valestin, J., & Ayyala, D. N. (2021) · Neurogastroenterology & Motility · doi:10.1111/nmo.14226 · Cited by 18 · see citing works
Melchior, C., Wilpart, K., Midenfjord, I., Trindade, I. A., Törnblom, H., Tack, J., Simrén, M., & Oudenhove, L. V. (2022) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001141 · Cited by 13 · see citing works
A Review of Select Centralized Pain Syndromes
Spiegel, D. R., Chatterjee, A. S., Mccroskey, A. L., Ahmadi, T., Simmelink, D., Oldfield, E. C., Pryor, C. R., Faschan, M., & Raulli, O. (2015) · Health Services Research and Managerial Epidemiology · doi:10.1177/2333392814567920 · Cited by 14 · see citing works
Limitations of current paradigms for visceral sensitivity testing
Oudenhove, L. V., Geeraerts, B., & Tack, J. F. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2007.01070.x · Cited by 13 · see citing works
Testing a biobehavioral model of irritable bowel syndrome
van der Veek, P. P. J., Dusseldorp, E., van Rood, Y. R., & Masclee, A. (2010) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0b013e328332f83f · Cited by 11 · see citing works
The Risk Factors of Chronic Pain in Victims of Violence: A Scoping Review
Uvelli, A., Duranti, C., Salvo, G., Coluccia, A., Gualtieri, G., & Ferretti, F. (2023) · Healthcare · doi:10.3390/healthcare11172421 · Cited by 10 · see citing works
Zhang, T., Chen, Y., Li, X., Zhang, J., & Duan, L. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1279266 · Cited by 11 · see citing works
Comorbidity Associated With Irritable Bowel Syndrome
Palsson, O. S., & Whitehead, W. E. (2005) · Psychiatric Annals · doi:10.3928/00485713-20050401-06 · Cited by 7 · see citing works
Self-citationUvelli, A., Pugliese, E., Masti, A., Salvo, G., Duranti, C., Gualtieri, G., & Ferretti, F. (2024) · Brain Sciences · doi:10.3390/brainsci14100953 · Cited by 7 · see citing works
Approach to a Child with Functional Abdominal Pain
Sood, M. R., & Matta, S. R. (2016) · The Indian Journal of Pediatrics · doi:10.1007/s12098-016-2111-5 · Cited by 6 · see citing works
Approach to the Patient with Constipation
Rao, S. S. C., & Camilleri, M. (2015) · Yamada's Textbook of Gastroenterology · doi:10.1002/9781118512074.ch42 · Cited by 6 · see citing works
Fifth European Paediatric Motility Meeting
Benninga, M. A., Peeters, B., Hennekam, R. C. M., Smout, A. J. P. M., Wenzl, T. G., van der Pol, R. J., Smits, M., van Wijk, M. P., Hassall, E. G., Thomson, M. A., et al. (2011) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31823cadc6 · Cited by 5 · see citing works
Approach to the Patient with Constipation
Rao, S. S. C. (2008) · doi:10.1002/9781444300758.ch20 · Cited by 5 · see citing works
van Tilburg, M. A. L. (2012) · Humana Press eBooks · doi:10.1007/978-1-60761-709-9_6 · Cited by 4 · see citing works
van Tilburg, M. A. L. (2016) · Springer eBooks · doi:10.1007/978-3-319-43268-7_6 · Cited by 3 · see citing works
Risk Factors for Chronic Pain in Women: The Role of Violence Exposure in a Case–Control Study
Uvelli, A., Pugliese, E., & Ferretti, F. (2025) · Life · doi:10.3390/life15060976 · Cited by 3 · see citing works
Talley, N. J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6189-2.00118-9 · Cited by 3 · see citing works
Uvelli, A., Ribaudo, C., Gualtieri, G., Coluccia, A., & Ferretti, F. (2023) · doi:10.21203/rs.3.rs-2981092/v1 · Cited by 2 · see citing works
Gastrointestinal symptoms in abused nonpatient women
Pallotta, N., Ribichini, E., Pezzotti, P., Belardi, F., Ciccantelli, B., Rivera, M., & Corazziari, E. S. (2024) · BMC Women s Health · doi:10.1186/s12905-024-03498-x · Cited by 1 · see citing works
Sood, M. R., & Sood, M. R. (2012) · Humana Press eBooks · doi:10.1007/978-1-60761-709-9_35 · Cited by 1 · see citing works
Sood, M. R., & Kovacic, K. K. (2016) · Springer eBooks · doi:10.1007/978-3-319-43268-7_38 · Cited by 1 · see citing works
Mirzaie, Z., Bastani, A., Haji-Aghamohammadi, A. A., Nooshabadi, M. R., Ahadinezhad, B., & Haghighian, H. K. (2020) · Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Māzandarān/Journal of Mazandaran University of Medical Sciences · Cited by 1 · see citing works
Rectal hyposensitivity : clinical and physiological impact on patients with chronic constipation
Vasudevan, S. (2014) · Cited by 1 · see citing works
Brain-Gut Interactions in Irritable Bowel Syndrome (IBS)
Grinsvall, C. (2018) · Gothenburg University Publications Electronic Archive (Gothenburg University) · Cited by 1 · see citing works
Chronic Functional Abdominal Pain
Foxx–Orenstein, A. E. (2016) · doi:10.1002/9781119127437.ch67 · Cited by 1 · see citing works
Somatoforme Störungen in der Gastroenterologie
Csef, H., & Hefner, J. (2007) · Psychosomatik und Konsiliarpsychiatrie · doi:10.1007/s11800-007-0025-9
Dyssynergic defecation and defecation disorders
Amieva‐Balmori, M., & Remes-Troche, J. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813037-7.00032-7
Physiology of the Pelvic Floor and the Anorectum
Athanasakos, E., & Cleeve, S. J. (2022) · Springer eBooks · doi:10.1007/978-3-030-97668-2_4
Integration of Biomedical and Psychosocial Issues in Pediatric Disorders of Gut-Brain Interaction
van Tilburg, M. A. L. (2022) · Springer eBooks · doi:10.1007/978-3-031-15229-0_7
- Authors
- Ringel, Y., Whitehead, W. E., Toner, B. B., Diamant, N. E., Hu, Y., Jia, H., Bangdiwala, S. I., & Drossman, D. A.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Centre for Addiction and Mental Health (CA)
- University of Toronto (CA)
- Corresponding author
- Ringel, Y
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2004-05-11
- Volume
- 53
- Issue
- 6
- Pages
- 838-842
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC1774075
- OpenAlex
- W2156488577
- Cited by
- 72
- References
- 41
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 5 · 2015: 2 · 2014: 2 · 2013: 2 · 2012: 5
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- UNC Libraries
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Keywords
- irritable bowel syndrome, sexual abuse, physical abuse, rectal hypersensitivity, rectal distension, fecal urgency, women, abuse history
- MeSH terms
- Adult, Analysis of Variance, Female, Humans, Rectum, Sex Offenses, Pain Threshold, Domestic Violence, Irritable Bowel Syndrome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
