New insights into the pathogenesis and pathophysiology of irritable bowel syndrome

Functional Bowel Disorders

Longstreth, G. F., Thompson, W. G., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.061 · Cited by 4,856 · see citing works

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome

Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G. S., Santini, D., Pasquinelli, G., Morselli-Labate, A. M., Grady, E. F., Bunnett, N. W., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.055 · Cited by 1,475 · see citing works

Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute <i>Campylobacter</i> enteritis and in post-dysenteric irritable bowel syndrome

Spiller, R. C., Jenkins, D., Thornley, J. P., Hebden, J. M., Wright, T., Skinner, M., & Neal, K. R. (2000) · Gut · doi:10.1136/gut.47.6.804 · Cited by 1,155 · see citing works

Activation of the mucosal immune system in irritable bowel syndrome

Chadwick, V. S., Chen, W., Shu, D., Paulus, B., Bethwaite, P., Tie, A., & Wilson, I. (2002) · Gastroenterology · doi:10.1053/gast.2002.33579 · Cited by 833 · see citing works

Eradication of Small Intestinal Bacterial Overgrowth Reduces Symptoms of Irritable Bowel Syndrome

Pimentel, M., Chow, E. J., & Lin, H. C. (2000) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03368.x · Cited by 780 · see citing works

Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome 1 ☆

Coates, M. D., Mahoney, C. R., Linden, D. R., Sampson, J. E., Chen, J. C., Blaszyk, H., Crowell, M. D., Sharkey, K. A., Gershon, M. D., & Mawe, G. M. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.03.013 · Cited by 761 · see citing works

Psychosocial Factors in the Irritable Bowel Syndrome

Drossman, D. A., McKee, D. C., Sandler, R. S., Mitchell, C. M., Cramer, E. M., Lowman, B. C., & Burger, A. L. (1988) · Gastroenterology · doi:10.1016/s0016-5085(88)80017-9 · Cited by 757 · see citing works

Analysis of the Fecal Microbiota of Irritable Bowel Syndrome Patients and Healthy Controls with Real-Time PCR

Malinen, E., Rinttila, T., Kajander, K., Matto, J., Kassinen, A., Krogius, L., Saarela, M., Korpela, R., & Palva, A. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40312.x · Cited by 699 · see citing works

Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome a double-blind, randomized, placebo-controlled study

Pimentel, M., Chow, E. J., & Lin, H. C. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07234.x · Cited by 670 · see citing works

Hypothalamic-Pituitary-Gut Axis Dysregulation in Irritable Bowel Syndrome: Plasma Cytokines as a Potential Biomarker?

Dinan, T. G., Quigley, E. M. M., Ahmed, S. M. M., Scully, P., O’Brien, S., O’Mahony, L., O’Mahony, S., Shanahan, F., & Keeling, P. W. N. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.033 · Cited by 636 · see citing works

Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders 1 1This study was registered with ClinicalTrials.gov (trial registry no. NCT00006157).

Drossman, D. A., Toner, B. B., Whitehead, W. E., Diamant, N. E., Dalton, C. B., Duncan, S., Emmott, S., Proffitt, V., Akman, D., Frusciante, K., et al. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00669-3 · Cited by 614 · see citing works

Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS

Dunlop, S. P., Jenkins, D., Neal, K. R., & Spiller, R. C. (2003) · Gastroenterology · doi:10.1053/j.gastro.2003.09.028 · Cited by 583 · see citing works

Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial

Atkinson, W., Sheldon, T. A., Shaath, N., & Whorwell, P. J. (2004) · Gut · doi:10.1136/gut.2003.037697 · Cited by 534 · see citing works

Food-Related gastrointestinal symptoms in the irritable bowel syndrome

Simrén, M., Månsson, A., Langkilde, A. M., Svedlund, J., Abrahamsson, H., Bengtsson, U., & Björnsson, E. S. (2001) · Digestion · doi:10.1159/000051878 · Cited by 529 · see citing works

Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome

Törnblom, H., Lindberg, G., Nyberg, B., & Veress, B. (2002) · Gastroenterology · doi:10.1053/gast.2002.37059 · Cited by 516 · see citing works

Increased mast cells in the irritable bowel syndrome

O’Sullivan, Clayton, Breslin, Harman, Bountra, Mclaren, & O’Morain (2000) · Neurogastroenterology &amp; Motility · doi:10.1046/j.1365-2982.2000.00221.x · Cited by 480 · see citing works

Symptoms of Psychologic Distress Associated With Irritable Bowel Syndrome

Whitehead, W. E., Bosmajian, L., Zonderman, A. B., Costa Jr., P. T., & Schuster, M. M. (1988) · Gastroenterology · doi:10.1016/s0016-5085(88)80018-0 · Cited by 480 · cited 1× · see citing works

Irritable bowel syndrome in general practice: prevalence, characteristics, and referral

Thompson, W. G., Heaton, K. W., Smyth, G. T., & Smyth, C. (2000) · Gut · doi:10.1136/gut.46.1.78 · Cited by 477 · see citing works

Abnormal Intestinal Permeability in Subgroups of Diarrhea-Predominant Irritable Bowel Syndromes

Dunlop, S. P., Hebden, J., Campbell, E., Naesdal, J., Olbe, L., Perkins, A. C., & Spiller, R. C. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00672.x · Cited by 476 · see citing works

Rectal distention testing in patients with irritable bowel syndrome: Sensitivity, specificity, and predictive values of pain sensory thresholds

Bouin, M., Plourde, V., Boivin, M., Riberdy, M., Lupien, F., Laganière, M., Verrier, P., & Poitras, P. (2002) · Gastroenterology · doi:10.1053/gast.2002.33601 · Cited by 470 · see citing works

Irritable bowel syndrome in twins: Heredity and social learning both contribute to etiology

Levy, R. L., Jones, K. R., Whitehead, W. E., Feld, S. I., Talley, N. J., & Corey, L. A. (2001) · Gastroenterology · doi:10.1053/gast.2001.27995 · Cited by 458 · see citing works

Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice

Verdú, E. F., Bercik, P., Verma-Gandhu, M., Huang, X.-X., Blennerhassett, P., Jackson, W., Mao, Y., Wang, L., Rochat, F., & Collins, S. M. (2006) · Gut · doi:10.1136/gut.2005.066100 · Cited by 448 · see citing works

Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome

Gwee, K.-A. (2003) · Gut · doi:10.1136/gut.52.4.523 · Cited by 415 · see citing works

Dyspepsia and Irritable Bowel Syndrome After a Salmonella Gastroenteritis Outbreak: One-Year Follow-up Cohort Study

Mearin, F., Pérez-Oliveras, M., Juan, A. P., Vinyet, J., Ibañez, A., Coderch, J., & Perona, M. C. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.04.012 · Cited by 406 · see citing works

Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis

Wang, L.-H., Fang, X.-C., & Pan, G.-Z. (2004) · Gut · doi:10.1136/gut.2003.021154 · Cited by 387 · cited 3× · see citing works

Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls

Wilder‐Smith, C. H., Schindler, D., Lövblad, K., Redmond, S. M., & Nirkko, A. (2004) · Gut · doi:10.1136/gut.2003.028514 · Cited by 386 · see citing works

Incidence and Epidemiology of Irritable Bowel Syndrome After a Large Waterborne Outbreak of Bacterial Dysentery

Marshall, J. K., Thabane, M. E., Garg, A. X., Clark, W. F., Salvadori, M. I., & Collins, S. M. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.05.053 · Cited by 370 · see citing works

Distinctive Clinical, Psychological, and Histological Features of Postinfective Irritable Bowel Syndrome

Dunlop, S. P., Jenkins, D., & Spiller, R. C. (2003) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07542.x · Cited by 359 · see citing works

Altered 5-Hydroxytryptamine Signaling in Patients With Constipation- and Diarrhea-Predominant Irritable Bowel Syndrome

Atkinson, W., Lockhart, S., Whorwell, P. J., Keevil, B., & Houghton, L. A. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.09.031 · Cited by 355 · see citing works

Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome

Dunlop, S. P., Coleman, N. S., Blackshaw, E., Perkins, A. C., Singh, G., Marsden, C. A., & Spiller, R. E. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00726-8 · Cited by 355 · see citing works

Colonic Motility Abnormality in Patients With Irritable Bowel Syndrome Exhibiting Abdominal Pain and Diarrhea

Chey, W. Y., Jin, H. O., Lee, M. H., Sun, S. W., & Lee, K. Y. (2001) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03804.x · Cited by 347 · see citing works

Posttraumatic Stress Disorder in Female Veterans

Dobie, D. J., Kivlahan, D. R., Maynard, C. C., Bush, K. R., Davis, T. M., & Bradley, K. A. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.4.394 · Cited by 342 · see citing works

Impaired transit and tolerance of intestinal gas in the irritable bowel syndrome

Serra, J. (2001) · Gut · doi:10.1136/gut.48.1.14 · Cited by 340 · see citing works

ORGANIC AND FUNCTIONAL DISORDERS IN 2000 GASTROENTEROLOGY OUTPATIENTS

Harvey, R., Salih, S., & Read, A. E. (1983) · The Lancet · doi:10.1016/s0140-6736(83)91802-0 · Cited by 331 · see citing works

Cerebral Activation in Patients With Irritable Bowel Syndrome and Control Subjects During Rectosigmoid Stimulation

Naliboff, B. D., Derbyshire, S. W. G., Munakata, J., Berman, S. M., Mandelkern, M. A., Chang, L., & Mayer, E. A. (2001) · Psychosomatic Medicine · doi:10.1097/00006842-200105000-00006 · Cited by 324 · see citing works

Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome – a longitudinal study in IBS and control subjects

Mättö, J., Maunuksela, L., Kajander, K., Palva, A., Korpela, R., Kassinen, A., & Saarela, M. (2005) · FEMS Immunology &amp; Medical Microbiology · doi:10.1016/j.femsim.2004.08.009 · Cited by 301 · see citing works

Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario

Marshall, J. K., Thabane, M., Garg, A. X., Clark, W., Meddings, J., Collins, S. M., & for the WEL Investigators (2004) · Alimentary Pharmacology &amp; Therapeutics · doi:10.1111/j.1365-2036.2004.02284.x · Cited by 292 · see citing works

Altered visceral perceptual and neuroendocrine response in patients with irritable bowel syndrome during mental stress

Posserud, I., Agerforz, P., Ekman, R., Björnsson, E. S., Abrahamsson, H., & Simrén, M. (2004) · Gut · doi:10.1136/gut.2003.017962 · Cited by 292 · see citing works

Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome

Sagami, Y., Shimada, Y., Tayama, J., Nomura, T., Satake, M., Endo, Y., Shoji, T., Karahashi, K., Hongo, M., & Fukudo, S. (2004) · Gut · doi:10.1136/gut.2003.018911 · Cited by 291 · see citing works

Sex-related differences in IBS patients: central processing of visceral stimuli

Naliboff, B. D., Berman, S. M., Chang, L., Derbyshire, S. W. G., Suyenobu, B. Y., Vogt, B. A., Mandelkern, M. A., & Mayer, E. A. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00400-1 · Cited by 291 · see citing works

Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome

Camilleri, M., Atanasova, E. A., Carlson, P. J., Ahmad, U. S., Kim, H. J., Viramontes, B. E., McKinzie, S., & Urrutia, R. A. (2002) · Gastroenterology · doi:10.1053/gast.2002.34780 · Cited by 285 · see citing works

Celiac disease–like abnormalities in a subgroup of patients with irritable bowel syndrome

Wahnschaffe, U., Ullrich, R., Riecken, E. O., & Schulzke, J. D. (2001) · Gastroenterology · doi:10.1053/gast.2001.29572 · Cited by 280 · see citing works

Psychosocial Factors are Linked to Functional Gastrointestinal Disorders: A Population Based Nested Case-Control Study

Richard Locke, G., Weaver, A. L., Joseph Melton, L., & Talley, N. J. (2004) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.04043.x · Cited by 278 · see citing works

Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis

Mayer, E. A., Berman, S. M., Suyenobu, B. Y., Labus, J. S., Mandelkern, M. A., Naliboff, B. D., & Chang, L. (2005) · Pain · doi:10.1016/j.pain.2005.03.023 · Cited by 275 · see citing works

Interleukin 10 genotypes in irritable bowel syndrome: evidence for an inflammatory component?: Table 1

Gonsalkorale, W. M., Perrey, C., Pravica, V, Whorwell, P. J., & Hutchinson, I. V. (2003) · Gut · doi:10.1136/gut.52.1.91 · Cited by 273 · see citing works

Amitriptyline reduces rectal pain related activation of the anterior cingulate cortex in patients with irritable bowel syndrome

Morgan, V (2005) · Gut · doi:10.1136/gut.2004.047423 · Cited by 269 · see citing works

Childhood Abuse and Later Medical Disorders in Women

Romans, S., Belaise, C., Martin, J., Morris, E., & Raffi, A. (2002) · Psychotherapy and Psychosomatics · doi:10.1159/000056281 · Cited by 263 · see citing works

Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women

Yeo, A., Boyd, P., Lumsden, S., Saunders, T., Handley, A., Stubbins, M., Knaggs, A., Asquith, S., Taylor, I., Bahari, B., et al. (2004) · Gut · doi:10.1136/gut.2003.035451 · Cited by 260 · see citing works

Familial Association in Adults With Functional Gastrointestinal Disorders

Locke, G. R., Zinsmeister, A. R., Talley, N. J., Fett, S. L., & Melton, L. J. (2000) · Mayo Clinic Proceedings · doi:10.4065/75.9.907 · Cited by 258 · cited 1× · see citing works

Central representation of visceral and cutaneous hypersensitivity in the irritable bowel syndrome

Verne, N. G., Himes, N. C., Robinson, M. E., Gopinath, K., Briggs, R. W., Crosson, B., & Price, D. D. (2003) · Pain · doi:10.1016/s0304-3959(02)00416-5 · Cited by 255 · see citing works

The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers

Houghton, L. A., Lea, R., Jackson, N., & Whorwell, P. J. (2002) · Gut · doi:10.1136/gut.50.4.471 · Cited by 235 · see citing works

Evidence of a Genetic Contribution to Functional Bowel Disorder

Morris‐Yates, A. D., Talley, N. J., Boyce, P. M., Nandurkar, S., & Andrews, G. (1998) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1998.440_j.x · Cited by 225 · see citing works

Intergenerational Transmission of Gastrointestinal Illness Behavior

Levy, R. L., Whitehead, W. E., Korff, M. R. V., & Feld, A. D. (2000) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(99)00825-4 · Cited by 219 · see citing works

Intestinal microecology and quality of life in irritable bowel syndrome patients

Si, J.-M. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i12.1802 · Cited by 218 · cited 1× · see citing works

Visceral hyperalgesia and intestinal dysmotility in a mouse model of postinfective gut dysfunction

Berčík, P., Wang, L., Verdu, E. F., Mao, Y., Blennerhassett, P. A., Khan, W. I., Kean, I. R. L., Tougas, G. H., & Collins, S. M. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.04.006 · Cited by 218 · see citing works

Role of Tumor Necrosis Factor-alpha and Interleukin-10 Gene Polymorphisms in Irritable Bowel Syndrome

van der Veek, P. P. J., van den Berg, M., de Kroon, Y. E., Verspaget, H. W., & Masclee, A. A. M. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.00257.x · Cited by 217 · see citing works

G-protein β3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia 1 ☆

Holtmann, G., Siffert, W., Haag, S., Mueller, N., Langkafel, M., Senf, W., Zotz, R. B., & Talley, N. J. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.01.006 · Cited by 213 · see citing works

An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome

Simrén, M., Abrahamsson, H., & Björnsson, E. S. (2001) · Gut · doi:10.1136/gut.48.1.20 · Cited by 209 · see citing works

Review article: intestinal serotonin signalling in irritable bowel syndrome

Mawe, G. M., Coates, M. D., & Moses, P. L. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.02858.x · Cited by 205 · see citing works

Irritable bowel syndrome patients show enhanced modulation of visceral perception by auditory stress

Dickhaus, B., Mayer, E. A., Firooz, N., Stains, J., Conde, F. A., Olivas, T. I., Fass, R., Chang, L., Mayer, M., & Naliboff, B. D. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07156.x · Cited by 204 · see citing works

Visceral hypersensitivity: facts, speculations, and challenges

Camilleri, M., COULIE, B., & Tack, J. F. (2001) · Gut · doi:10.1136/gut.48.1.125 · Cited by 204 · see citing works

Stress-induced disruption of colonic epithelial barrier: role of interferon-γ and myosin light chain kinase in mice

Ferrier, L., Mazelin, L., Cénac, N., Desreumaux, P., Janin, A., Émilie, D., Colombel, J., Villar, R. G., Fioramonti, J., & Bueno, L. P. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)01057-6 · Cited by 197 · see citing works

Mucosal mast cell counts correlate with visceral hypersensitivity in patients with diarrhea predominant irritable bowel syndrome

PARK, J. H., RHEE, P., KIM, H. S., LEE, J. H., KIM, Y., KIM, J. J., & RHEE, J. C. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2005.04143.x · Cited by 196 · see citing works

Longitudinal Change in Perceptual and Brain Activation Response to Visceral Stimuli in Irritable Bowel Syndrome Patients

Naliboff, B. D., Berman, S. M., Suyenobu, B. Y., Labus, J. S., Chang, L., Stains, J., Mandelkern, M. A., & Mayer, E. A. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.05.014 · Cited by 195 · see citing works

Sensation of bloating and visible abdominal distension in patients with irritable bowel syndrome

Chang, L., Lee, O. Y., Naliboff, B. D., Schmulson, M. J., & Mayer, E. A. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.05336.x · Cited by 191 · see citing works

Quality of Life in Patients with Irritable Bowel Syndrome Seen in Referral Centers Versus Primary Care: The Impact of Gender and Predominant Bowel Pattern

Simrén, M., Abrahamsson, H., Svedlund, J., & Björnsson, E. S. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655201750153476 · Cited by 189 · see citing works

Quality of life in inflammatory bowel disease in remission: The impact of IBS-like symptoms and associated psychological factors

Simrén, M. (2002) · The American Journal of Gastroenterology · doi:10.1016/s0002-9270(01)04037-0 · Cited by 186 · see citing works

Effect of acute physical and psychological stress on gut autonomic innervation in irritable bowel syndrome

Murray, C. D. R., Flynn, J., Ratcliffe, L., Jacyna, M. R., Kamm, M. A., & Emmanuel, A. V. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.08.057 · Cited by 185 · see citing works

Lipid-induced intestinal gas retention in irritable bowel syndrome

Serra, J., Salvioli, B., Azpiroz, F., & Malagelada, J. (2002) · Gastroenterology · doi:10.1053/gast.2002.35394 · Cited by 184 · see citing works

Coping Strategies and Interpersonal Support in Patients With Irritable Bowel Syndrome and Inflammatory Bowel Disease

Jones, M. P., Wessinger, S. B., & Crowell, M. D. (2006) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2005.12.012 · Cited by 180 · see citing works

Randomized, double‐blind, placebo‐controlled trial of prednisolone in post‐infectious irritable bowel syndrome

Dunlop, S., Jenkins, D., Neal, K. R., Næsdal, J., Borgaonker, M., Collins, S. M., & Spiller, R. E. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01640.x · Cited by 178 · see citing works

Intergenerational Transmission of Gastrointestinal Illness Behavior

Levy, R. L., Whitehead, W. E., Korff, M. R. V., et al. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01766.x · Cited by 178 · see citing works

Antibiotics increase functional abdominal symptoms

Maxwell, P., Rink, E., Kumar, D., & Mendall, M. A. (2002) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2002.05428.x · Cited by 176 · see citing works

Increased platelet depleted plasma 5-hydroxytryptamine concentration following meal ingestion in symptomatic female subjects with diarrhoea predominant irritable bowel syndrome

Houghton, L. A., Atkinson, W., Whitaker, R. P., Whorwell, P. J., & Rimmer, M. J. (2003) · Gut · doi:10.1136/gut.52.5.663 · Cited by 176 · see citing works

Detection of Bacterial Overgrowth in IBS Using the Lactulose H2 Breath Test: Comparison with 14C-d-Xylose and Healthy Controls

Walters, B., & Vanner, S. J. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40795.x · Cited by 172 · see citing works

Gut‐focused hypnotherapy normalizes disordered rectal sensitivity in patients with irritable bowel syndrome

Lea, R., Houghton, L. A., Calvert, E. L., Larder, S., Gonsalkorale, W. M., Whelan, V., Randles, J., Cooper, P., Cruickshanks, P., Miller, V., et al. (2003) · Alimentary Pharmacology &amp; Therapeutics · doi:10.1046/j.1365-2036.2003.01486.x · Cited by 172 · see citing works

Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome

Drossman, D. A., Ringel, Y., Vogt, B. A., Leserman, J., Lin, W., Smith, J. K., & Whitehead, W. E. (2003) · Gastroenterology · doi:10.1053/gast.2003.50103 · Cited by 170 · see citing works

Association of distinct α2 adrenoceptor and serotonin transporter polymorphisms with constipation and somatic symptoms in functional gastrointestinal disorders

Kim, H. J., Camilleri, M., Carlson, P., Cremonini, F., Ferber, I., Stephens, D., Mckinzie, S., Zinsmeister, A., & Urrutia, R. (2004) · Gut · doi:10.1136/gut.2003.030882 · Cited by 168 · see citing works

Familial aggregation of irritable bowel syndrome: a prospective study

Kalantar, J. S., Locke, G. R., Zinsmeister, A. R., Beighley, C. M., & Talley, N. J. (2003) · Gut · doi:10.1136/gut.52.12.1703 · Cited by 168 · see citing works

Does bacterial gastroenteritis predispose people to functional gastrointestinal disorders? A prospective, community-based, case-control study

Parry, S. D., Stansfield, R., Jelley, D., Gregory, W., Phillips, E., Barton, J. R., & Welfare, M. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07664.x · Cited by 160 · see citing works

Post‐infectious irritable bowel syndrome in patients with Shigella infection

Ji, S.-W., Park, H., LEE, D., Song, Y. G., Choi, J., & LEE, S. (2005) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2005.03574.x · Cited by 158 · see citing works

Sex specific alterations in autonomic function among patients with irritable bowel syndrome

Tillisch, K., Mayer, E. A., Labus, J. S., Stains, J., Chang, L., & Naliboff, B. D. (2005) · Gut · doi:10.1136/gut.2004.058685 · Cited by 156 · see citing works

Patients and Nonconsulters with Irritable Bowel Syndrome Reporting a Parental History of Bowel Problems Have More Impaired Psychological Distress

Kanazawa, M., Endo, Y., Whitehead, W. E., Kano, M., Hongo, M., & Fukudo, S. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000034570.52305.10 · Cited by 154 · see citing works

Central Processing of Rectal Pain in Patients With Irritable Bowel Syndrome: An Fmri Study

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