A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice

Superoxide Dismutase

McCord, J. M., & Fridovich, I. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63504-5 · Cited by 12,952

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

Obesity is associated with macrophage accumulation in adipose tissue

Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041

Human gut microbes associated with obesity

Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760

Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., et al. (2007) · Diabetes · doi:10.2337/db06-1491 · Cited by 6,638

Dose translation from animal to human studies revisited.

Reagan‐Shaw, S., Nihal, M., & Ahmad, N. (2008) · The FASEB Journal · doi:10.1096/fj.07-9574lsf · Cited by 6,524

The metabolic syndrome

Eckel, R. H., Alberti, K., Grundy, S. M., & Zimmet, P. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61794-3 · Cited by 6,317

Brown Adipose Tissue: New Challenges for Prevention of Childhood Obesity. A Narrative Review

Verduci, E., Calcaterra, V., Profio, E. D., Fiore, G., Rey, F., Magenes, V. C., Todisco, C. F., Carelli, S., & Zuccotti, G. (2021) · Nutrients · doi:10.3390/nu13051450 · Cited by 20

Epicatechin and β-glucan from whole highland barley grain ameliorates hyperlipidemia associated with attenuating intestinal barrier dysfunction and modulating gut microbiota in high-fat-diet-fed mice

Liu, Z., Tang, R., Liu, J., Zhang, Z., Li, Y., & Zhao, R. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134917 · Cited by 19

Akkermansia muciniphila fermentation culture based on a novel bionic large intestine dynamic digestion model

Li, Z., Zhu, L., Hu, G.-A., Sun, Z., Zhan, X.-B., & Gao, M. (2021) · Food Bioscience · doi:10.1016/j.fbio.2021.101260 · Cited by 19

Dietary supplementation of red-osier dogwood polyphenol extract changes the ileal microbiota structure and increases Lactobacillus in a pig model

Zheng, S., Song, J., Qin, X., Yang, K., Liu, M., Yang, C., & Nyachoti, C. M. (2021) · AMB Express · doi:10.1186/s13568-021-01303-8 · Cited by 19

Propionylated high-amylose maize starch alleviates obesity by modulating gut microbiota in high-fat diet-fed mice

Xie, Z., Yao, M., Castro-Mejía, J. L., Ma, M., Zhu, Y., Fu, X., Huang, Q., & Zhang, B. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105447 · Cited by 19

Total Sn-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute Modulated Bile Acid Metabolism and Intestinal Microbiota Composition in Rats

Zhu, L., Fang, S., Zhang, H., Sun, X., Yang, P., Wan, J., Zhang, Y., Lu, W., & Yu, L. L. (2023) · Nutrients · doi:10.3390/nu15234929 · Cited by 19

Baicalein, a dietary flavonoid, enhances the insulin‐sensitizing effect of metformin to prevent type 2 diabetes via the regulation of lipid metabolism and gut microenvironment

Xing, Y., Liu, H., Zhang, D., Jiang, H., Xiu, Z., & Dong, Y. (2024) · Food Frontiers · doi:10.1002/fft2.348 · Cited by 19

Exploring the potential of apple (poly)phenols: A systematic review of randomized controlled trials on metabolic diseases prevention

Shoji, T., Masumoto, S., Miura, T., & Desjardins, Y. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2024.104419 · Cited by 19

Prebiotic proanthocyanidins inhibit bile reflux–induced esophageal adenocarcinoma through reshaping the gut microbiome and esophageal metabolome

Weh, K. M., Howard, C. L., Zhang, Y., Tripp, B. A., Clarke, J., Howell, A. B., Rubenstein, J. H., Abrams, J. A., Westerhoff, M. A., & Kresty, L. A. (2024) · JCI Insight · doi:10.1172/jci.insight.168112 · Cited by 19

Mechanisms underlying the metabolic beneficial effect of curcumin intervention: Beyond anti-inflammation and anti-oxidative stress

Jin, T. (2018) · Obesity Medicine · doi:10.1016/j.obmed.2018.11.002 · Cited by 19

A polyphenol-rich cranberry extract protects against endogenous exposure to persistent organic pollutants during weight loss in mice

Choi, B. S.-Y., Varin, T. V., St‐Pierre, P., Pilon, G., Tremblay, A., & Marette, A. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111832 · Cited by 19

Dietary fat and low fiber in purified diets differently impact the gut-liver axis to promote obesity-linked metabolic impairments

Daniel, N., Perazza, L. R., Varin, T. V., Trottier, J., Marcotte, B., St‐Pierre, P., Barbier, O., Chassaing, B., & Marette, A. (2021) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00028.2021 · Cited by 19

Bioactive compounds from Prosthechea karwinskii decrease obesity, insulin resistance, pro-inflammatory status, and cardiovascular risk in Wistar rats with metabolic syndrome

Barragán-Zarate, G. S., Alexander-Aguilera, A., Lagunez-Rivera, L., Solano, R., & Soto-Rodríguez, I. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114376 · Cited by 19

Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats

Gebeyew, K., Chen, K., Wassie, T., Azad, M. A. K., He, J., Jiang, W., Wu, S., He, Z., & Tan, Z. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.774766 · Cited by 20

The predicted mechanisms and evidence of probiotics on type 2 diabetes mellitus (T2DM)

Bajinka, O., Dovi, K. S., Simbilyabo, L., Conteh, I., & Tan, Y. (2023) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2022.2163260 · Cited by 20

Thinking Outside the Cereal Box: Noncarbohydrate Routes for Dietary Manipulation of the Gut Microbiota

Reese, A. T., & Carmody, R. N. (2018) · Applied and Environmental Microbiology · doi:10.1128/aem.02246-18 · Cited by 19

Gestational Diabetes and the Gut Microbiota: Fibre and Polyphenol Supplementation as a Therapeutic Strategy

Pheiffer, C., Riedel, S., Dias, S. C., & Adam, S. (2024) · Microorganisms · doi:10.3390/microorganisms12040633 · Cited by 18

Selenium Yeast Alleviates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice by Reducing Proinflammatory Cytokines and Regulating the Gut Microbiota and Their Metabolites

Wu, Z., Li, Y., Jiang, M., Sang, L.-X., & Chang, B. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s449335 · Cited by 12

The relationship between antioxidant activity, first electrochemical oxidation potential, and spin population of flavonoid radicals

Miličević, A. (2019) · Archives of Industrial Hygiene and Toxicology · doi:10.2478/aiht-2019-70-3290 · Cited by 18

Decaisnea insignis Seed Oil Inhibits Trimethylamine-N-oxide Formation and Remodels Intestinal Microbiota to Alleviate Liver Dysfunction in l -Carnitine Feeding Mice

Zhang, X., Wu, Q., Zhao, Y., & Yang, X. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b05383 · Cited by 18

Xyloglucan compounded inulin or arabinoxylan against glycometabolism disorder via different metabolic pathways: Gut microbiota and bile acid receptor effects

Chen, H., Zhou, S., Li, J., Huang, X., Cheng, J., Jiang, X., Qin, W., Liu, Y., Liu, A., Zhang, Q. R., et al. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104162 · Cited by 18

The Impact of a Dried Fruit and Vegetable Supplement and Fiber Rich Shake on Gut and Health Parameters in Female Healthcare Workers: A Placebo-Controlled, Double-Blind, Randomized Clinical Trial

van der Merwe, M., Moore, D., Hill, J. L., Keating, F. H., Buddington, R. K., Bloomer, R. J., Wang, A., & Bowman, D. D. (2021) · Microorganisms · doi:10.3390/microorganisms9040843 · Cited by 18

Dietary components regulate chronic diseases through gut microbiota: a review

Zhang, Y., Zhou, M., Zhou, Y., & Xiao, G. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.12732 · Cited by 19

Medicinal plants with cholesterol-lowering effect marketed in the Buenos Aires-La Plata conurbation, Argentina: An Urban Ethnobotany study

Hurrell, J. A., Puentes, J. P., & Arenas, P. M. (2015) · Ethnobiology and Conservation · doi:10.15451/ec2015-9-4.7-1-19 · Cited by 18

The interaction between various food components and intestinal microbiota improves human health through the gut–X axis: independently or synergistically

Li, F. N., Peng, X., & Li, W. (2025) · Food & Function · doi:10.1039/d4fo04430d · Cited by 17

The Impact of Diet on the Colonization of Beneficial Microbes from an Ecological Perspective

Chen, Z., Xiao, C., Zhang, J., Jian, S., Li, P., Lin, J., He, C., Chen, Z., Qi, Y., Shi, J., et al. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c02086 · Cited by 19

ASTRAGALOSIDE Ⅳ MODULATES GUT MACROPHAGES M1/M2 POLARIZATION BY RESHAPING GUT MICROBIOTA AND SHORT CHAIN FATTY ACIDS IN SEPSIS

Yang, T., Xie, S., Cao, L., Li, M., Ding, L., Wang, L., Pang, S., Wang, Z., & Geng, L. (2023) · Shock · doi:10.1097/shk.0000000000002262 · Cited by 17

A review on the effects of flavan-3-ols, their metabolites, and their dietary sources on gut barrier integrity

Dobani, S., Pourshahidi, L. K., Ternan, N. G., McDougall, G. J., Pereira‐Caro, G., Bresciani, L., Mena, P. R., Almutairi, T. M., Crozier, A., Tuohy, K. M., et al. (2025) · Food & Function · doi:10.1039/d4fo04721d · Cited by 17

Synergistic effect of cranberry extract and losartan against aluminium chloride-induced hepatorenal damage associated cardiomyopathy in rats

Galal, S. M., Hasan, H. F., Abdel-Rafei, M. K., & kiki, S. M. E. (2018) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2018.1465437 · Cited by 17

Tuber flours improve intestinal health and modulate gut microbiota composition

Xu, T., Huang, W., Liang, J., Zhong, Y., Chen, Q., Jie, F., & Lu, B. (2021) · Food Chemistry X · doi:10.1016/j.fochx.2021.100145 · Cited by 17

Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity

Daoust, L., Choi, B. S.-Y., Agrinier, A.-L., Varin, T. V., Ouellette, A., Mitchell, P. L., Samson, N., Pilon, G., Levy, E. H., Desjardins, Y., et al. (2022) · Gut · doi:10.1136/gutjnl-2021-326475 · Cited by 16

Mulberry leaf extract improves non-specific immunity and antioxidant capacity of largemouth bass (Micropterus salmoides) fed a high-starch diet

Jing, T., Luo, H., Junwa, H., Li, Z., Li, Y., Honghao, J., Xinxi, Z., Ke, Z., Wenbo, S., Mengdan, H., et al. (2022) · Frontiers in Marine Science · doi:10.3389/fmars.2022.1029360 · Cited by 16

Traditional Chinese medicines (TCMs) with varied meridians (Gui-Jing) differentially alleviate the adverse impact of Coptis chinensis on gut microbiota

Yang, Y., Su, W., Zang, C., Tan, Y., Zhang, Y., Zhou, Z., Lu, W., Wu, S., Zhang, X., & Wu, C. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116256 · Cited by 16

Recent advances in the extraction, purification, structural-property correlations, and antiobesity mechanism of traditional Chinese medicine-derived polysaccharides: a review

Zhi, N., Chang, X., Wang, X., Guo, J. X., Chen, J., & Gui, S. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1341583 · Cited by 16

Cranberry extract attenuates indomethacin-induced gastriculcer in rats via its potential atioxidant and anti-inflammatory effects

Abdul-Majeed, Z., Al-Atrakji, M. Q. Y. M. A., & Ridha‐Salman, H. (2025) · Journal of Molecular Histology · doi:10.1007/s10735-025-10438-y · Cited by 16

Rethinking paradigms for studying mechanisms of action of plant bioactives

Kay, C. D. (2015) · Nutrition Bulletin · doi:10.1111/nbu.12178 · Cited by 17

High phenolics Rutgers Scarlet Lettuce improves glucose metabolism in high fat diet‐induced obese mice

Cheng, D. M., Roopchand, D. E., Poulev, A., Kuhn, P. E., Armas, I., Johnson, W. D., Oren, A., Ribnicky, D., Zelzion, E., Bhattacharya, D., et al. (2016) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600290 · Cited by 16

Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression

Zeng, K., Tian, L., Sirek, A., Shao, W., Liu, L., Chiang, Y., Chernoff, J., Ng, D. S., Weng, J., & Jin, T. (2017) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjx031 · Cited by 16

Effect of cranberry supplementation on liver enzymes and cardiometabolic risk factors in patients with NAFLD: a randomized clinical trial

Shirazi, K. M., Shirinpour, E., Shirazi, A. M., & Nikniaz, Z. (2021) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03436-6 · Cited by 16

Omnifarious fruit polyphenols: an omnipotent strategy to prevent and intervene diabetes and related complication?

Chen, Y., Qie, X., Quan, W., Zeng, M., Qin, F., Chen, J., Adhikari, B., & He, Z. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.2000932 · Cited by 16

Global research trends on the links between the gut microbiota and diabetes between 2001 and 2021: A bibliometrics and visualized study

Zhang, B., Jin, Z., Zhai, T., Ding, Q., Yang, H., Wang, J., Zhang, L., & Zhao, L. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1011050 · Cited by 17

Vaccinium as Potential Therapy for Diabetes and Microvascular Complications

Huang, H. C., Luo, Y., Wang, Q., Zhang, Y., Li, Z., He, R., Chen, X., & Dong, Z. (2023) · Nutrients · doi:10.3390/nu15092031 · Cited by 16

The role of intestinal microbiota and microRNAs in the anti-inflammatory effects of cranberry: from pre-clinical to clinical studies

Taïbi, A., Lofft, Z., Imbriaco, B. L., & Comelli, E. M. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1092342 · Cited by 16

The gut microbiome in the fight against obesity: The potential of dietary factors

Ahmad, J., Khan, I. A., Zengin, G., & Mahomoodally, M. F. (2023) · The FASEB Journal · doi:10.1096/fj.202300864rr · Cited by 15

Intestinal Microbiome Metabolism of Cranberry (Vaccinium macrocarpon) Proanthocyanidin Dimers, but Not Trimers, Is Altered by Dysbiosis in Ulcerative Colitis Ex Vivo

Diaz, M. S., Mertens‐Talcott, S. U., & Talcott, S. T. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c00042 · Cited by 15

Phenolic compounds in dietary target the regulation of gut microbiota: Role in health and disease

Zhang, Q., Xu, Y., Bukvički, D., Peng, Y., Li, F., Zhang, Q., Yan, J., Lin, S., Liu, S., & Qin, W. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105107 · Cited by 16

Dietary proanthocyanidins for improving gut immune health

Liu, C., & Bolling, B. W. (2024) · Current Opinion in Food Science · doi:10.1016/j.cofs.2024.101133 · Cited by 15

Akkermansia muciniphila: A Potential Target for the Prevention of Diabetes

He, K., An, F., Zhang, H., Yan, D., Li, T., Wu, J., & Wu, R. (2024) · Foods · doi:10.3390/foods14010023 · Cited by 17

Red lentil supplementation reduces the severity of dextran sodium sulfate-induced colitis in C57BL/6 male mice

Gräf, D., Monk, J. M., Wu, W., Wellings, H. R., Robinson, L. E., & Power, K. A. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103625 · Cited by 15

Gut Microbiota and Liver Injury (I)—Acute Liver Injury

Wu, G., Win, S., Than, T. A., Chen, P., & Kaplowitz, N. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-2385-4_3 · Cited by 15

Human Microbiota: A Neglected “Organ” in Precision Medicine

Bi, Y., Qin, N., & Yang, R. (2015) · doi:10.11979/idtm.201502005 · Cited by 15

Asperlin Stimulates Energy Expenditure and Modulates Gut Microbiota in HFD-Fed Mice

Wu, C., Zhou, Y., Qi, G., Liu, D., Cao, X., Yu, J., Zhang, R., Lin, W., & Guo, P. (2019) · Marine Drugs · doi:10.3390/md17010038 · Cited by 15

Two polyphenol-rich Brazilian fruit extracts protect from diet-induced obesity and hepatic steatosis in mice

Ballard, C. R., dos Santos, E. F., Dubois, M.-J., Pilon, G., Cazarin, C. B. B., Maróstica, M. R., & Marette, A. (2020) · Food & Function · doi:10.1039/d0fo01912g · Cited by 15

Interplay Between Dietary Bioactive Compounds and Gut Microbiota in Modulating Obesity-Associated Inflammation and Metabolic Dysfunction

Seifishahpar, M., Kalupahana, N. S., Kim, J. H., & Moustaïd‐Moussa, N. (2025) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-111224-024937 · Cited by 17

Feeding Frequency Modulates the Intestinal Transcriptome Without Affecting the Gut Microbiota in Pigs With the Same Daily Feed Intake

Zhang, H., Xia, P., Feng, L., Jia, M., & Su, Y. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.743343 · Cited by 15

Walnut Meal Extracts Rich In Polyphenols Mitigate Insulin Resistance and Modulate Gut Microbiota in High Fat Diet-Fed Rats

He, X., Chen, D., Yang, D., Zhang, X., Ma, Y., Yang, J., Chen, C., & Zhao, S. (2022) · Journal of Medicinal Food · doi:10.1089/jmf.2021.k.0189 · Cited by 14

Targeting the gut to prevent and counteract metabolic disorders and pathologies during aging

Milenković, D., Capel, F., Combaret, L., Comte, B., Dardevet, D. P., Evrard, B., Guillet, C., Monfoulet, L., Pinel, A., Polakof, S., et al. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2089870 · Cited by 14

Is there a role for microbiome-based approach in common variable immunodeficiency?

Poto, R., Ianiro, G., de Paulis, A., Spadaro, G., Marone, G., Gasbarrini, A., & Varricchi, G. (2023) · Clinical and Experimental Medicine · doi:10.1007/s10238-023-01006-3 · Cited by 16

Assessing the Gut Microbiota's Ability to Metabolize Oligomeric and Polymeric Flavan‐3‐ols from Aronia and Cranberry

Lessard‐Lord, J., Roussel, C., Guay, V., & Desjardins, Y. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300641 · Cited by 14

Dietary polysaccharides from dragon fruit pomace, a co-product of the fruit processing industry, exhibit therapeutic potential in high-fat diet-induced metabolic disorders

Li, G., He, Y., Liew, A., Huang, C., Song, B., Jia, X., Sathuvan, M., Zhong, S., & Cheong, K. (2025) · Food Research International · doi:10.1016/j.foodres.2025.115818 · Cited by 14

Berries

Sangiovanni, E., Fumagalli, M., & Dell’Agli, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805377-5.00018-7 · Cited by 14

Z-ligustilide and n-Butylidenephthalide Isolated from the Aerial Parts of Angelica tenuissima Inhibit Lipid Accumulation In Vitro and In Vivo

Lee, W., Koo, H. R., Choi, Y., Choi, J. G., Oh, M. S., Jin, X. Y., Choo, M., Park, S., Jeong, Y., Chung, S., et al. (2019) · Planta Medica · doi:10.1055/a-0901-1307 · Cited by 14

Cranberry extract-based formulations for preventing bacterial biofilms

Greene, A. C., Acharya, A. P., Lee, S. B., Gottardi, R., Zaleski, E., & Little, S. R. (2020) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00837-x · Cited by 14

Rapeseed polysaccharides alleviate overweight induced by high-fat diet with regulation of gut microbiota in rats

Yang, C., Wang, X., Deng, Q., & Huang, F. (2021) · Oil Crop Science · doi:10.1016/j.ocsci.2021.09.001 · Cited by 14

Catechins as a Potential Dietary Supplementation in Prevention of Comorbidities Linked with Down Syndrome

Noll, C., Kandiah, J., Moroy, G., Gu, Y., Dairou, J., & Janel, N. (2022) · Nutrients · doi:10.3390/nu14102039 · Cited by 14

Comparing Transgenic Production to Supplementation of ω-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders

Daniel, N., Barz, M. L., Mitchell, P. L., Varin, T. V., Bourdeau‐Julien, I., Farabos, D., Pilon, G., Gauthier, J., Garofalo, C., Kang, J. X., et al. (2022) · Function · doi:10.1093/function/zqac069 · Cited by 14

The Role of Green Tea on the Regulation of Gut Microbes and Prevention of High-Fat Diet-Induced Metabolic Syndrome in Mice

Mei, H., Li, J., Liu, S., Jeyaraj, A., Zhuang, J., Wang, Y., Chen, X., Yuan, Q., & Li, X. (2023) · Foods · doi:10.3390/foods12152953 · Cited by 14

Metabolite Profiling of the Gut Microbiome in Mice with Dietary Administration of Black Raspberries

Tu, P., Bian, X., Chi, L., Xue, J., Gao, B., Lai, Y., Ru, H., & Lü, K. (2020) · ACS Omega · doi:10.1021/acsomega.9b00237 · Cited by 14

Metabolic Fate and Cardiometabolic Effects of Phenolic Compounds from Red‐Fleshed Apple in Hypercholesterolemic Rats: A Comparative Study with Common White‐Fleshed Apple. The AppleCOR Study

Yuste, S., Ludwig, I. A., Romero, M., Piñol, C., Catalán, Ú., Pedret, A., Valls, R. M., Fernández‐Castillejo, S., Motilva, M., Macià, A., et al. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202001225 · Cited by 14

Therapeutic potential of dietary nutrients and medicinal foods against metabolic disorders: Targeting Akkermansia muciniphila

Xu, W., Zhang, S., Yang, Y., Zhan, J., Zang, C., Yu, H., & Wu, C. (2024) · Food Frontiers · doi:10.1002/fft2.341 · Cited by 13

Effect of l -arabinose and lactulose combined with Lactobacillus plantarum on obesity induced by a high-fat diet in mice

Wang, Q., Xiong, J., He, Y., He, J., Cai, M., Luo, Z., Zhang, T., & Zhou, X. D. (2024) · Food & Function · doi:10.1039/d4fo00369a · Cited by 13

Urolithin B protects mice from diet-induced obesity, insulin resistance, and intestinal inflammation by regulating gut microbiota composition

Chen, P., Wang, R., Lei, J., Feng, L., & Zhou, B. (2024) · Food & Function · doi:10.1039/d4fo02545h · Cited by 13

Glucosinolate extract from radish (Raphanus sativus L.) seed attenuates high-fat diet-induced obesity: insights into gut microbiota and fecal metabolites

Zhu, Q., Zhang, P., Liu, D., Tang, L., Yu, J., Zhang, C., & Jiang, G. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1442535 · Cited by 13

Procyanidin B1 and p -coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism

Liu, Z., Yang, Y., Xu, Y., Zhang, Z., Tang, R., Liu, J., Jiang, H., & Zhao, R. (2024) · Food & Function · doi:10.1039/d4fo02805h · Cited by 13

Assessing the efficacy of tocotrienol-rich fraction vitamin E in obese children with non-alcoholic fatty liver disease: a single-blind, randomized clinical trial

Al-Baiaty, F. D. R., Ishak, S., Zaki, F. M., Masra, F., Aziz, D. A. A., Zin, W. N. W. M., Hing, E. Y., Zaman, A., Wahab, N. A., Nawawi, K. N. M., et al. (2024) · BMC Pediatrics · doi:10.1186/s12887-024-04993-8 · Cited by 14

Polyphenol Phase‐II Metabolites are Detectable in Human Plasma after Ingestion of13C Labeled Spinach—a Pilot Intervention Trial in Young Healthy Adults

Passon, M., Bühlmeier, J., Zimmermann, B. F., Stratmann, A., Latz, S., Stehle, P., & Galensa, R. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201701003 · Cited by 13

Vaccinium macrocarpon Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute Pancreatitis

Santana, D. G., Oliveira, A. S., Souza, M. T. D. S., Santos, J. T. D. C., Hassimotto, N. M. A., Silva, A. M. D. O. E., Grespan, R., & Camargo, E. A. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/9646937 · Cited by 13

Special emphasis on the therapeutic potential of microparticles with antidiabetic effect: Trends and possible applications

de Oliveira, W. Q., Neri-Numa, I. A., Arruda, H. S., Lopes, A. T., Pelissari, F. M., Barros, F. F. C., & Pastore, G. M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.02.043 · Cited by 13

Dietary intake of yacon roots (Smallanthus sonchifolius) affects gut microbiota and fecal mucin and prevents intestinal inflammation in mice

Higashimura, Y., Hirabayashi, M., Nishikawa, H., Inoüe, R., Nagai, E., Matsumoto, K., Enomoto, T., Mizushima, K., Takagi, T., & Naito, Y. (2021) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.20-203 · Cited by 15

The postnatal window is critical for the development of sex-specific metabolic and gut microbiota outcomes in offspring

Daoust, L., Choi, B. S.-Y., Lacroix, S., Vilela, V. R., Varin, T. V., Dudonné, S., Pilon, G., Roy, D., Levy, E. H., Desjardins, Y., et al. (2021) · Gut Microbes · doi:10.1080/19490976.2021.2004070 · Cited by 13

Targeting Lipid Rafts as a Rapid Screening Strategy for Potential Antiadipogenic Polyphenols along with the Structure–Activity Relationship and Mechanism Elucidation

Wang, R., Zhu, W., Dang, M., Deng, X., Shi, X. L., Zhang, Y., Li, K., & Li, C. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c00444 · Cited by 13

(20R)-Panaxadiol as a Natural Active Component with Anti-Obesity Effects on ob/ob Mice via Modulating the Gut Microbiota

Lv, Y., Zhang, Y., Feng, J., Zhao, T., Zhao, J., Ge, Y., Yang, X., Han, H., Zhang, M., Chen, L., et al. (2022) · Molecules · doi:10.3390/molecules27082502 · Cited by 14

Changes in systolic blood pressure, postprandial glucose, and gut microbial composition following mango consumption in individuals with overweight and obesity

Keathley, J., Kearney, M., Garneau, V., de Toro‐Martín, J., Varin, T. V., Pilon, G., Couture, P., Marette, A., Vohl, M., & Couillard, C. (2022) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2021-0637 · Cited by 13

High polyphenolic cranberry beverage alters specific fecal microbiota but not gut permeability following aspirin challenge in healthy obese adults: A randomized, double-blind, crossover trial

Solch-Ottaiano, R. J., Judkins, T. C., Matott, S. H., McDermott, C. E., Nieves, C., Wang, Y. H. D., Colee, J., Tagliamonte, M. S., Dissanayake, U., Mai, V., et al. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105332 · Cited by 13

Fecal Microbiota Composition as a Metagenomic Biomarker of Dietary Intake

Melo, N. C. D. O., Cuevas‐Sierra, A., Cruz, E. F., Víctor de la, O., & Martínez, J. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054918 · Cited by 13

Berberine-containing natural-medicine with boiled peanut-OIT induces sustained peanut-tolerance associated with distinct microbiota signature

Srivastava, K. D., Cao, M., Fidan, Ö., Shi, Y., Yang, N., Nowak-Wegrzyn, A. H., Miao, M., Zhan, J., Sampson, H. A., & Li, X.-M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1174907 · Cited by 13

Impact of increasing concentration of tart and sweet cherries juices concentrates on healthy mice gut microbiota

Othaim, A. A., Marasini, D., & Carbonero, F. G. (2020) · Food Frontiers · doi:10.1002/fft2.46 · Cited by 13

Efficacy of flavonoids in non-alcoholic fatty liver disease: an updated systematic review and meta-analysis

Liu, Q., Luan, H., Duan, Z., Ai, J., Wang, Y., & Chen, P. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1660065 · Cited by 15

The Gut Microbiota–Polyphenol–NLRP3 Inflammasome Axis: A Key Regulatory Network Linking Diet to Chronic Inflammation

Mosca, L., Pagano, C., Tafuri, M. G., Maio, G. D., Rejano-Gordillo, C. M., Marca, R. D., D’Angelo, S., Monda, M., Messina, G., Polito, R., et al. (2026) · Nutrients · doi:10.3390/nu18101483 · Cited by 13

Grape Polyphenols May Prevent High-Fat Diet–Induced Dampening of the Hypothalamic–Pituitary–Adrenal Axis in Male Mice

Mezhibovsky, E., Tveter, K. M., Villa-Rodríguez, J. A., Bacalia, K. M. A., Kshatriya, D., Desai, N., Cabales, A., Wu, Y., Sui, K., Duran, R. M., et al. (2023) · Journal of the Endocrine Society · doi:10.1210/jendso/bvad095 · Cited by 12

Emerging and multifaceted potential contributions of polyphenols in the management of type 2 diabetes mellitus

González, I., Lindner, C., Schneider, I., Díaz-Bautista, E., Morales, M. A., & Armando Rojas, R. (2024) · World Journal of Diabetes · doi:10.4239/wjd.v15.i2.154 · Cited by 12

Polyphenols Influence the Development of Endometrial Cancer by Modulating the Gut Microbiota

Baranowska‐Wójcik, E., Winiarska‐Mieczan, A., Olcha, P., Kwiecień, M., Jachimowicz-Rogowska, K., Nowakowski, Ł., Miturski, A., & Gałczyński, K. (2024) · Nutrients · doi:10.3390/nu16050681 · Cited by 12

Complexes of Soluble Dietary Fiber and Polyphenols from Lotus Root Regulate High-Fat Diet-Induced Hyperlipidemia in Mice

Zheng, Z., Gao, W., Zhu, Z., Li, S., Chen, X., Cravotto, G., Sui, Y., & Zhou, L. (2024) · Antioxidants · doi:10.3390/antiox13040466 · Cited by 12

Co-Supplementation of Baobab Fiber and Arabic Gum Synergistically Modulates the In Vitro Human Gut Microbiome Revealing Complementary and Promising Prebiotic Properties

Duysburgh, C., Govaert, M., Guillemet, D., & Marzorati, M. (2024) · Nutrients · doi:10.3390/nu16111570 · Cited by 12

Cellulose-like chitosan microfibrils facilitate targeted release and enhance the prolonged residence time of quercetin-selenium nanoparticles for Alzheimer’s disease treatment

Fang, C., Chen, Q., Zheng, G., Zhang, F., Li, Z., Mei, J., Wu, X., Chen, X., Zeng, K., & Yang, L. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.125129 · Cited by 12

Tetrahydrocurcumin Alleviates Metabolic Dysfunction-Associated Steatohepatitis in Mice by Regulating Serum Lipids, Bile Acids, and Gut Microbiota

Peng, S., Moran, M., Luo, P., Liu, J., Wang, J., & Chen, Y. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26030895 · Cited by 12

Akkermansia muciniphila MucT harnesses dietary polyphenols as xenosiderophores for enhanced iron uptake

Rodríguez-Daza, M.-C., Boeren, S. A., Tytgat, H. L. P., Desjardins, Y., & de Vos, W. M. (2025) · Nature Communications · doi:10.1038/s41467-025-64477-w · Cited by 12

Effect of Red Orange and Lemon Extract-Enriched Diet in Suckling Lambs’ Fecal Microbiota

Ferrara, M., Sgarro, M. F., Maggiolino, A., Damiano, S., Iannaccone, F., Mulè, G., & Palo, P. D. (2021) · Agriculture · doi:10.3390/agriculture11070572 · Cited by 12

A Freeze-Dried Cranberry Powder Consistently Enhances SCFA Production and Lowers Abundance of Opportunistic Pathogens In Vitro

Khoo, C., Duysburgh, C., Marzorati, M., den Abbeele, P. V., & Zhang, D. (2022) · BioTech · doi:10.3390/biotech11020014 · Cited by 12

TOTUM ‐63, a plant‐based polyphenol‐rich extract, improves glycaemic control in subjects with prediabetes or early stage newly‐diagnosed type 2 diabetes in a randomized, double‐blind, placebo‐controlled trial

Sirvent, P., Chavanelle, V., Otero, Y. F., Bargetto, M., Joubioux, F. L., Boisseau, N., Maugard, T., Cazaubiel, M., Pereira, B., Guigas, B., et al. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14817 · Cited by 12

A triptan too far?

Goadsby, P. J. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.64.2.143 · Cited by 94

A polyphenol-rich cranberry extract reverses insulin resistance and hepatic steatosis independently of body weight loss

Anhê, F. F., Nachbar, R. T., Varin, T. V., Vilela, V. R., Dudonné, S., Pilon, G., Fournier, M., Lecours, M.-A., Desjardins, Y., Roy, D., et al. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.10.003 · Cited by 191

Triggering Akkermansia with dietary polyphenols: A new weapon to combat the metabolic syndrome?

Anhê, F. F., Pilon, G., Roy, D., Desjardins, Y., Levy, E. H., & Marette, A. (2016) · Gut Microbes · doi:10.1080/19490976.2016.1142036 · Cited by 155

Rhubarb Supplementation Prevents Diet-Induced Obesity and Diabetes in Association with Increased Akkermansia muciniphila in Mice

Régnier, M., Rastelli, M., Morissette, A., Suriano, F., Roy, T. L., Pilon, G., Delzenne, N. M., Marette, A., Hul, M. V., & Cani, P. D. (2020) · Nutrients · doi:10.3390/nu12102932 · Cited by 77

Proanthocyanidin‐Rich Cranberry Extract Lowers Glycemia in Established Obesity by Delaying Glucose Absorption

Beji, S., Mouchiroud, M., Tribouillard, L., Efole, B., Perazza, L. R., Favereaux, L., Poirier, A., Idris, W., Gélinas, Y., Varin, T., et al. (2026) · The FASEB Journal · doi:10.1096/fj.202601382r