The DOI matches its Crossref record; 74 of the 75 references it cites were found in a registry or an index.
A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice
Open accessAbstract
Objective: The increasing prevalence of obesity and type 2 diabetes (T2D) demonstrates the failure of conventional treatments to curb these diseases. The gut microbiota has been put forward as a key player in the pathophysiology of diet-induced T2D. Importantly, cranberry (Vaccinium macrocarpon Aiton) is associated with a number of beneficial health effects. We aimed to investigate the metabolic impact of a cranberry extract (CE) on high fat/high sucrose (HFHS)-fed mice and to determine whether its consequent antidiabetic effects are related to modulations in the gut microbiota. Design: C57BL/6J mice were fed either a chow or a HFHS diet. HFHS-fed mice were gavaged daily either with vehicle (water) or CE (200 mg/kg) for 8 weeks. The composition of the gut microbiota was assessed by analysing 16S rRNA gene sequences with 454 pyrosequencing. Results: CE treatment was found to reduce HFHS-induced weight gain and visceral obesity. CE treatment also decreased liver weight and triglyceride accumulation in association with blunted hepatic oxidative stress and inflammation. CE administration improved insulin sensitivity, as revealed by improved insulin tolerance, lower homeostasis model assessment of insulin resistance and decreased glucose-induced hyperinsulinaemia during an oral glucose tolerance test. CE treatment was found to lower intestinal triglyceride content and to alleviate intestinal inflammation and oxidative stress. Interestingly, CE treatment markedly increased the proportion of the mucin-degrading bacterium Akkermansia in our metagenomic samples. Conclusions: CE exerts beneficial metabolic effects through improving HFHS diet-induced features of the metabolic syndrome, which is associated with a proportional increase in Akkermansia spp. population.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Researchers have confirmed that a polyphenol-rich cranberry extract and metformin attenuate diet-induced metabolic syndrome in mice in a gut microbiota-dependent manner (16, 17).”
In the citing paper
“These improvements were coupled to dramatic 7-to-10-fold blooms of Akkermansia muciniphila”
From The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism (2016) · cites this paper as [96]
In the citing paper
“Mice fed high-fat diets supplemented with polyphenols showed reduced diet-induced weight gain and adiposity, improved insulin sensitivity, and diminished markers of intestinal inflammation and oxidative stress compared to controls20, 96.”
From The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism (2016) · cites this paper as [96]
In the citing paper
“Furthermore, the metabolic benefits of dietary polyphenol, cranberry extract, and metformin are associated with increased amount of this bacterial species in the gut.”
From Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe −/− Mice (2016) · cites this paper as [37]
In the citing paper
“Increased Akkermansia abundance has been linked with reduced intestinal permeability and gut-to-blood leakage of endotoxins (eg, lipopolysaccharides), thereby alleviating diet-induced obesity and insulin resistance (49).”
From Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice (2021) · cites this paper as [49]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice
Caricilli, A. M., Picardi, P. K., de Abreu, L. L., Ueno, M., Prada, P. O., Ropelle, E. R., Hirabara, S. M., Castoldi, Â., Moraes‐Vieira, P. M., Câmara, N. O. S., et al. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001212 · Cited by 285
RetractedApple Peel Polyphenols and Their Beneficial Actions on Oxidative Stress and Inflammation
Denis, M. C., Fürtös, A., Dudonné, S., Montoudis, A., Garofalo, C., Desjardins, Y., DELVIN, E. E., & Levy, E. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053725 · Cited by 124
Self-citationRetractedMcCord, J. M., & Fridovich, I. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63504-5 · Cited by 12,952
An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
Obesity is associated with macrophage accumulation in adipose tissue
Weisberg, S. P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R. L., & Ferrante, A. W. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319246 · Cited by 10,041
Human gut microbes associated with obesity
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760
Metabolic Endotoxemia Initiates Obesity and Insulin Resistance
Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., et al. (2007) · Diabetes · doi:10.2337/db06-1491 · Cited by 6,638
Dose translation from animal to human studies revisited.
Reagan‐Shaw, S., Nihal, M., & Ahmad, N. (2008) · The FASEB Journal · doi:10.1096/fj.07-9574lsf · Cited by 6,524
Eckel, R. H., Alberti, K., Grundy, S. M., & Zimmet, P. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61794-3 · Cited by 6,317
Research works printed but not linked: 2
- 10.1172/JCI200525102 · DOI · Paper page
- 10.1096/fj.10-164921 · DOI · Paper page
Cited by
Sorted by citations
Items 301–400 of 1,000
Power, K. A., Lepp, D., Zarepoor, L., Monk, J. M., Wu, W., Tsao, R., & Liu, R. (2015) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2015.09.028 · Cited by 70
Westfall, S., Lomis, N., & Prakash, S. (2018) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2018.1458731 · Cited by 70
Liu, D., Wen, B., Zhu, K., Luo, Y. L., Li, J., Li, Y., Lin, H., Huang, J., & Liu, Z. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-019-09764-5 · Cited by 70
Polyphenols as modulators of pre‐established gut microbiota dysbiosis: State‐of‐the‐art
Molinari, R., Merendino, N., & Costantini, L. (2021) · BioFactors · doi:10.1002/biof.1772 · Cited by 72
Wang, R., Zhang, L., Zhang, Q., Zhang, J., Liu, S., Li, C., & Wang, L. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c07441 · Cited by 68
Su, L., Zeng, Y., Li, G., Chen, J., & Chen, X. (2022) · Phytotherapy Research · doi:10.1002/ptr.7575 · Cited by 71
Metformin, Cognitive Function, and Changes in the Gut Microbiome
Rosell-Díaz, M., & Fernández‐Real, J. M. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnad029 · Cited by 68
Targeted Approaches for In Situ Gut Microbiome Manipulation
Lee, H. L., Shen, H., Hwang, I. Y., Ling, H., Yew, W. S., Lee, Y. S., & Chang, M. W. (2018) · Genes · doi:10.3390/genes9070351 · Cited by 68
Flux, M. C., & Lowry, C. A. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104578 · Cited by 70
Therapeutic Efficacy of Antioxidants in Ameliorating Obesity Phenotype and Associated Comorbidities
Tun, S., Spainhower, C. J., Cottrill, C. L., Lakhani, H. V., Pillai, S. S., Dilip, A., Chaudhry, H., Shapiro, J. I., & Sodhi, K. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01234 · Cited by 69
Moorthy, M., Sundralingam, U., & Palanisamy, U. D. (2021) · Foods · doi:10.3390/foods10020299 · Cited by 67
Bai, X., Fu, R., Duan, Z., Wang, P., Zhu, C., & Fan, D. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110465 · Cited by 67
Guo, X., Cao, X., Fang, X., Guo, A., & Li, E. (2021) · Food & Function · doi:10.1039/d0fo03423a · Cited by 68
The emerging role of dark berry polyphenols in human health and nutrition
Higbee, J., Solverson, P. M., Zhu, M. J., & Carbonero, F. G. (2022) · Food Frontiers · doi:10.1002/fft2.128 · Cited by 69
Wang, K., Jin, X., You, M., Tian, W., Leu, R. K. L., Topping, D. L., Conlon, M. A., Wu, L., & Hu, F. (2017) · Nutrients · doi:10.3390/nu9080875 · Cited by 67
Rocha, D. M. U. P., Caldas, A. P. S., da Silva, B. P., Hermsdorff, H. H. M., & Alfenas, R. D. C. G. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1430019 · Cited by 67
Mehmood, A., Zhao, L., Wang, Y., Pan, F., Hao, S., Zhang, H., Iftikhar, A., & Usman, M. A. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110180 · Cited by 67
Zheng, S., Huang, K., Zhao, C., Xu, W., Sheng, Y., Luo, Y., & He, X. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.09.007 · Cited by 68
Li, Y., Bai, D., Lu, Y., Chen, J., Yang, H., Mu, Y., Xu, J., Huang, X., & Li, L. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.05.130 · Cited by 66
Han, X., Guo, J., Yin, M., Liu, Y., You, Y., Zhan, J., & Huang, W. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000149 · Cited by 68
Diabetes and the Gut Microbiome
Lau, W. L., Tran, T., Rhee, C. M., Kalantar-Zadeh, K., & Vaziri, N. D. (2021) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2021.03.005 · Cited by 65
Diet-Derived Phytochemicals Targeting Colon Cancer Stem Cells and Microbiota in Colorectal Cancer
Ganesan, K., Jayachandran, M., & Xu, B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21113976 · Cited by 65
Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats
Bhaswant, M., Fanning, K., Netzel, M. E., Mathai, M. L., Panchal, S. K., & Brown, L. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.10.006 · Cited by 66
Different subtype strains of Akkermansia muciniphila abundantly colonize in southern China
Guo, X., Zhang, J., Wu, F., Zhang, M., Yi, M., & Peng, Y. (2015) · Journal of Applied Microbiology · doi:10.1111/jam.13022 · Cited by 70
Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats
Bhaswant, M., Shafie, S. R., Mathai, M. L., Mouatt, P., & Brown, L. (2016) · Nutrition · doi:10.1016/j.nut.2016.12.009 · Cited by 70
Guo, C., Han, L., Li, M., & Yu, L. (2020) · Nutrients · doi:10.3390/nu12010265 · Cited by 65
Morand, C., de Roos, B., García‐Conesa, M., Gibney, E. R., Landberg, R., Manach, C., Milenković, D., Rodriguez‐Mateos, A., de Wiele, T. V., & Tomás-Barberán, F. A. (2020) · Proceedings of The Nutrition Society · doi:10.1017/s0029665120000014 · Cited by 65
Effects of an acute exercise bout on serum hepcidin levels
Domínguez, R., Sánchez-Oliver, A., Mata-Ordoñez, F., Feria-Madueño, A., Grimaldi-Puyana, M., López-Samanes, Á., & Pérez-López, A. (2018) · Nutrients · doi:10.3390/nu10020209 · Cited by 64
“Flavonoids are an abundant nutraceutical compound of cranberries that have been shown to promote oxidative [89], antioxidant, and anti-inflammatory effects [90,91].”
BackgroundEfficacy and Mechanisms of Oleuropein in Mitigating Diabetes and Diabetes Complications
Zheng, S., Huang, K., & Tong, T. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c01404 · Cited by 64
Wang, L., Gao, M., Kang, G., & Huang, H. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.798038 · Cited by 66
Le Barz, M., Daniel, N., Varin, T. V., Naimi, S., Demers‐Mathieu, V., Pilon, G., Audy, J., Laurin, É., Roy, D., Urdaci, M. C., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201801672r · Cited by 63
Self-citationWu, T., Grootaert, C., Pitart, J., Kardum, N., Kamiloğlu, S., Possemiers, S., Glibetić, M., Smagghe, G. J., Raes, K., de Wiele, T. V., et al. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800607 · Cited by 63
Zhu, L., Ye, C., Hu, B., Xia, H., Bian, Q., Liu, Y., Kong, M., Zhou, S., & Liu, H. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109019 · Cited by 62
Wang, R., Yao, L., Meng, T., Li, C., & Wang, L. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.133438 · Cited by 62
Singh, D. P., Singh, S., Bijalwan, V., Kumar, V., Khare, P., Baboota, R. K., Singh, P., Boparai, R. K., Singh, J., Kondepudi, K. K., et al. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1561-5 · Cited by 63
Faheem, S. A., Saeed, N. M., El‐Naga, R. N., Ayoub, I. M., & Azab, S. S. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00218 · Cited by 62
Klurfeld, D. M., Davis, C. D., Karp, R. W., Allen-Vercoe, E., Chang, E. B., Chassaing, B., Fahey, G. C., Hamaker, B. R., Holscher, H. D., Lampe, J. W., et al. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00058.2018 · Cited by 61
Self-citationBatista, Â. G., da Silva-Maia, J. K., Mendonça, M. C. P., Soares, E. S., Lima, G. C., Bogusz, S., da Cruz‐Höfling, M. A., & Maróstica, M. R. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.07.020 · Cited by 61
Han, R., Qiu, H., Zhong, J., Zheng, N., Li, B., Hong, Y., Ma, J., Wu, G., Chen, L., Sheng, L., et al. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153544 · Cited by 61
Zhang, W., Qi, S., Xue, X., Naggar, Y. A., Wu, L., & Wang, K. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.671150 · Cited by 65
Martinou, E., Stefanova, I., Iosif, E., & Angelidi, A. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063339 · Cited by 64
Weh, K. M., Clarke, J., & Kresty, L. A. (2016) · Antioxidants · doi:10.3390/antiox5030027 · Cited by 61
Xu, J., Liu, T., Li, Y., Liu, W., Ding, Z., Ma, H., Seeram, N. P., Mu, Y., Huang, X., & Li, L. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801307 · Cited by 61
Song, H., Shen, X., Chu, Q., & Zheng, X. (2021) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.11535 · Cited by 61
Wang, Z., Sun, Y., Han, Y., Chen, X., Gong, P., Zhai, P., Yao, W., Ba, Q., & Wang, H. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154652 · Cited by 60
Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin
Sun, W., Hua, S., Li, X., Shen, L., Wu, H., & Ji, H. (2023) · Nature Communications · doi:10.1038/s41467-023-36079-x · Cited by 60
Kowalska, K., & Olejnik, A. M. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.11.001 · Cited by 62
Debnath, S. C., & Goyali, J. C. (2020) · Molecules · doi:10.3390/molecules25040788 · Cited by 62
Yin, J., Zhang, B., Yu, Z., Hu, Y., Lv, H., Ji, X., Wang, J., Peng, B., & Wang, S. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.1c00706 · Cited by 61
The anti-obesogenic effects of dietary berry fruits: A review
Jiang, H., Zhang, W., Li, X., Xü, Y., Cao, J., & Jiang, W. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110539 · Cited by 60
Zhao, T., Zhan, L., Zhou, W., Chen, W., Luo, J., Zhang, L., Weng, Z., Zhao, C., & Liu, S. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.647529 · Cited by 61
Cao, Y., Yao, G., Sheng, Y., Li, Y., Wang, Z., Yang, Z. Y., Zhuang, P., & Zhang, Y. (2019) · Journal of Diabetes Research · doi:10.1155/2019/1872134 · Cited by 59
Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue
Luo, C., Wei, X., Song, J., Xu, X., Huang, H., Fan, S., Zhang, D., Han, L., & Lin, J. (2022) · Molecules · doi:10.3390/molecules27217377 · Cited by 61
American cranberries and health benefits – an evolving story of 25 years
Zhao, S., Liu, H., & Gu, L. (2018) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.8882 · Cited by 61
Bellenger, J., Bellenger, S., Escoula, Q., Bidu, C., & Narce, M. (2019) · Biochimie · doi:10.1016/j.biochi.2019.01.017 · Cited by 59
Garcinol Reduces Obesity in High‐Fat‐Diet‐Fed Mice by Modulating Gut Microbiota Composition
Lee, P., Teng, C., Nagabhushanam, K., Ho, C., & Pan, M. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800390 · Cited by 58
Host–Microbe Interplay in the Cardiometabolic Benefits of Dietary Polyphenols
Anhê, F. F., Choi, B. S.-Y., Dyck, J. R. B., Schertzer, J. D., & Marette, A. (2019) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2019.04.002 · Cited by 60
Self-citationNaito, Y., Ushiroda, C., Mizushima, K., Inoüe, R., Yasukawa, Z., Abe, A., & Takagi, T. (2020) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.20-39 · Cited by 58
Polyphenols, the new frontiers of prebiotics
Nazzaro, F., Fratianni, F., Feo, V. D., Battistelli, A., da Cruz, A. G., & Coppola, R. (2020) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2020.06.002 · Cited by 58
Effects of Ramadan and Non-ramadan Intermittent Fasting on Gut Microbiome
Mousavi, S. N., Rayyani, E., Heshmati, J., Tavasolian, R., & Rahimlou, M. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.860575 · Cited by 57
Gut microbiota is a potential goalkeeper of dyslipidemia
Lei, L., Zhao, N., Zhang, L., Chen, J., Liu, X., & Piao, S. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.950826 · Cited by 62
Pang, J., Raka, F., Heirali, A., Shao, W., Liu, D., Gu, J., Feng, J. N., Mineo, C., Shaul, P. W., Qian, X., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-38259-1 · Cited by 58
Li, F., Zeng, K., & Ming, J. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2278169 · Cited by 58
Gut Microbiota-Derived Metabolites in the Development of Diseases
Shen, G., Wu, J., Ye, B., & Qi, N. (2021) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2021/6658674 · Cited by 58
Ai, X., Wu, C., Yin, T., Zhur, O., Liu, C., Yan, X., Yi, C., Liu, D., Xiao, L., Li, W., et al. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.682290 · Cited by 56
Shao, G., Liu, Y., Lu, L., Wang, L., Ji, G., & Xu, H. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.117999 · Cited by 59
Kang, I., Espı́n, J. C., Carr, T. P., Tomás-Barberán, F. A., & Chung, S. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.02.006 · Cited by 57
Li, T., Gao, J., Du, ., & Mao, X. (2019) · Food & Function · doi:10.1039/c8fo01967c · Cited by 56
Yang, Y., Zhang, J., & Zhou, Q. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1835819 · Cited by 56
Anti-obesity natural products and gut microbiota
Li, S., Zeng, S.-L., & Liu, E. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110819 · Cited by 56
The Role of the Gut Microbiome and Trimethylamine Oxide in Atherosclerosis and Age-Related Disease
Hage, R. E., Al-Arawe, N., & Hinterseher, I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032399 · Cited by 56
Bioactive Dairy-Fermented Products and Phenolic Compounds: Together or Apart
Wróblewska, B., Kuliga, A., & Wnorowska, K. (2023) · Molecules · doi:10.3390/molecules28248081 · Cited by 55
Heo, J.-Y., Seo, M., Park, H., Lee, W. K., Guan, L. L., Yoon, J. H., Caetano-Anollés, K., Ahn, H., Kim, S., Kang, Y.-M., et al. (2016) · Scientific Reports · doi:10.1038/srep33566 · Cited by 56
Zhou, J., & Zhang, X. (2019) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(19)30101-3 · Cited by 55
Altered gut bacterial–fungal interkingdom networks in patients with current depressive episode
Jiang, H., Pan, L., Zhang, X., Zhang, Z., Zhou, Y., & Ruan, B. (2020) · Brain and Behavior · doi:10.1002/brb3.1677 · Cited by 55
Strauch, R. C., & Lila, M. A. (2021) · Food Science & Nutrition · doi:10.1002/fsn3.2335 · Cited by 55
Insights on β-glucan as a prebiotic coadjuvant in the treatment of diabetes mellitus: A review
Sivieri, K., de Oliveira, S. M., Marquez, A. D. S., Pérez‐Jiménez, J., & Diniz, S. N. (2022) · Food Hydrocolloids for Health · doi:10.1016/j.fhfh.2022.100056 · Cited by 57
Tu, P., Bian, X., Chi, L., Gao, B., Ru, H., Knobloch, T. J., Weghorst, C. M., & Lü, K. (2018) · ACS Omega · doi:10.1021/acsomega.8b00064 · Cited by 54
Role of flavonoids in controlling obesity: molecular targets and mechanisms
Mahboob, A., Samuel, S. M., Mohamed, A., Wani, M. Y., Ghorbel, S., Miled, N., Büsselberg, D., & Châari, A. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1177897 · Cited by 60
Denis, M.-C., Roy, D., Yeganeh, P. R., Desjardins, Y., Varin, T. V., Haddad, N. E., Amre, D. K., Sané, A. T., Garofalo, C., Fürtös, A., et al. (2016) · Clinical Science · doi:10.1042/cs20160524 · Cited by 57
Self-citationThe role of nutrition in influencing mechanisms involved in environmentally mediated diseases
Hennig, B., Petriello, M. C., Gamble, M. V., Surh, Y., Kresty, L. A., Frank, N., Rangkadilok, N., Ruchirawat, M., & Suk, W. A. (2018) · Reviews on Environmental Health · doi:10.1515/reveh-2017-0038 · Cited by 54
Sandoval-Ramírez, B. A., Catalán, Ú., Pedret, A., Valls, R. M., Motilva, M., Rubió, L., & Solà, R. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.09.027 · Cited by 54
He, X.-Q., Liu, D., Liu, H., Wu, D., Li, H., Zhang, X.-S., & Gan, R. (2022) · Nutrients · doi:10.3390/nu14112208 · Cited by 56
Tingler, A. M., & Engevik, M. A. (2025) · Infection and Immunity · doi:10.1128/iai.00503-24 · Cited by 58
Phylogenetic profile of gut microbiota in healthy adults after moderate intake of red wine
Barroso, E., Muñoz‐González, I., Jiménez, E., Bartolomé, B., Moreno-Arribas, M. V., Peláez, C., Martínez‐Cuesta, M. C., & Requena, T. (2016) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600620 · Cited by 55
Bekiares, N., Krueger, C. G., Meudt, J. J., Shanmuganayagam, D., & Reed, J. D. (2017) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2016.0167 · Cited by 53
Kumar, S., Patial, V., Soni, S., Sharma, S., Pratap, K., Kumar, D., & Padwad, Y. S. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00537 · Cited by 53
Effect of raw potato starch on the gut microbiome and metabolome in mice
Bang, S.-J., Lee, E., Song, E., Nam, Y., Seo, M., Kim, H., Park, C., Lim, M. Y., & Seo, D. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.04.085 · Cited by 53
Li, L., Lu, C., Zhang, X., Ning, Z., Mayne, J., Ye, Y., Stintzi, A., Liu, J., & Figeys, D. (2020) · Gut Microbes · doi:10.1080/19490976.2020.1755413 · Cited by 53
Song, H., Shen, X., Wang, F., Li, Y., & Zheng, X. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202001090 · Cited by 52
Wang, Y., Ablimit, N., Zhang, Y., Li, J., Wang, X., Liu, J., Miao, T., Wu, L., Wang, H., Wang, Z., et al. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.09.150 · Cited by 53
The Emerging Biotherapeutic Agent: Akkermansia
Kalia, V. C., Gong, C., Shanmugam, R., Lin, H. M., Zhang, L., & Lee, J.-K. (2021) · Indian Journal of Microbiology · doi:10.1007/s12088-021-00993-9 · Cited by 53
de Oliveira, F. L., Arruda, T. Y. P., Morzelle, M. C., Pereira, A. P. A., & Neves, S. J. F. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111841 · Cited by 55
Roquetto, A. R., Monteiro, N. E. S., Moura, C. S., Toreti, V. C., de Pace, F., Santos, A., Park, Y. K., & Amaya‐Farfán, J. (2015) · Food Research International · doi:10.1016/j.foodres.2015.07.026 · Cited by 52
Roles of Commensal Microbiota in Pancreas Homeostasis and Pancreatic Pathologies
Leal‐Lopes, C., Velloso, F. J., Campopiano, J. C., Sogayar, M. C., & Correa, R. G. (2015) · Journal of Diabetes Research · doi:10.1155/2015/284680 · Cited by 54
Dudonné, S., Varin, T. V., Anhê, F. F., Dubé, P., Roy, D., Pilon, G., Marette, A., Levy, E. H., Jacquot, C., Urdaci, M. C., et al. (2015) · PharmaNutrition · doi:10.1016/j.phanu.2015.04.002 · Cited by 52
Self-citationRokhsefat, S., Lin, A., & Comelli, E. M. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4032-6 · Cited by 54
Kim, N.-H., Jegal, J., Kim, N.-H., Heo, J., Rho, J., Yang, M. H., & Jeong, E. J. (2018) · Nutrients · doi:10.3390/nu10111734 · Cited by 52
Zhang, P., Jiao, H., Wang, C., Lin, Y., & You, S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00325 · Cited by 52
Yang, X., Dong, B., An, L., Zhang, Q., Chen, Y., Wang, H., & Song, Z. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.756491 · Cited by 52
Metadata
- Authors
- Anhê, F. F., Roy, D., Pilon, G., Dudonné, S., Matamoros, S., Varin, T. V., Garofalo, C., Moine, Q., Desjardins, Y., Levy, E., & Marette, A.
- Affiliations
- Institut universitaire de cardiologie et de pneumologie de Québec (CA)
- Université Laval (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Corresponding author
- Marette, André
- ORCID
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2014-07-30
- Volume
- 64
- Issue
- 6
- Pages
- 872-883
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W2099456560
- Cited by
- 1,137
- References
- 75
- Citations by year
- 2026: 53 · 2025: 85 · 2024: 86 · 2023: 98 · 2022: 128 · 2021: 175 · 2020: 134 · 2019: 117 · 2018: 83 · 2017: 71 · 2016: 62 · 2015: 45
- FWCI
- 24.34
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Université Laval
- Ministère du Développement Économique, de l’Innovation et de l’Exportation
- Agence Universitaire de la Francophonie
- Institut sur la Nutrition et les Aliments Fonctionnels
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- cranberry extract, cranberry, polyphenols, diet-induced obesity, insulin resistance, type 2 diabetes, gut microbiota, Akkermansia, high-fat high-sugar diet, visceral obesity, hepatic steatosis, hepatic oxidative stress, intestinal inflammation, metabolic syndrome, mucin-degrading bacteria
- MeSH terms
- Animals, Enteritis, Hepatitis, Homeostasis, Insulin Resistance, Intestines, Lipids, Lipopolysaccharides, Liver, Male, Mice, Inbred C57BL, Organ Size, Plant Extracts, Triglycerides, Endotoxemia, Vaccinium macrocarpon, Lipid Metabolism, Mice, Obesity, Abdominal, Diet, High-Fat, Polyphenols, Verrucomicrobia, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review