British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis
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These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included medical representatives from hepatology and gastroenterology groups as well as patient representatives from PSC Support. The guidelines aim to support general physicians, gastroenterologists and surgeons in managing adults with PSC or those presenting with similar cholangiopathies which may mimic PSC, such as IgG4 sclerosing cholangitis. It also acts as a reference for patients with PSC to help them understand their own management. Quality of evidence is presented using the AGREE II format. Guidance is meant to be used as a reference rather than for rigid protocol-based care as we understand that management of patients often requires individual patient-centred considerations.
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MRI/MRC is the best non-invasive tool to assess large bile duct changes in PSC.
“As universally agreed, MRI/MRC is the best non-invasive tool to assess large bile duct changes in PSC.[20][21][22]”
From EASL Clinical Practice Guidelines on sclerosing cholangitis (2022) · cites this paper as [22]
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Flagged first, then by citations
Research works printed but not linked: 2
- funding from British Liver Trust, PSC Partners, PSC Support, EASL, SMR - Involvement in clinical trials in PSC and sits on the advisory board for FALK and Intercept. GH -medical adviser for PSC Support, speaker fees and educational support from Falk Pharma. on August 2, 2023 by guest. Protected by copyright. http://gut.bmj.com/ Gut: first published as 10.1136/gutjnl-2018-317993 on 1 June 2019. Downloaded from RefeRences
- Al Mamari S, Djordjevic J, Halliday JS, et al. Improvement of serum alkaline phosphatase to. J Hepatol 2013;58:329-34.
Cited by
Sorted by citations
EASL Clinical Practice Guidelines on sclerosing cholangitis
Chazouilleres, O., Beuers, U., Bergquist, A., Karlsen, T. H., Levy, C., Samyn, M., Schramm, C., & Trauner, M. (2022) · Journal of Hepatology · doi:10.1016/j.jhep.2022.05.011 · Cited by 419 · see citing works
Ponsioen, C. Y., Assis, D. N., Boberg, K. M., Bowlus, C. L., Deneau, M., Thorburn, D., Aabakken, L., Färkkilä, M., Petersen, B., Rupp, C., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.07.046 · Cited by 95 · see citing works
Self-citationThe Role of B Cells and B Cell Therapies in Immune-Mediated Liver Diseases
Cargill, T., & Culver, E. L. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.661196 · Cited by 46 · see citing works
Erichsen, R., Olén, O., Sachs, M. C., Pedersen, L., Halfvarson, J., Askling, J., Ekbom, A., Ludvigsson, J. F., & Sørensen, H. T. (2021) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-20-1241 · Cited by 31 · see citing works
Wannhoff, A., Brune, M., Knierim, J., Weiss, K. H., Rupp, C., & Gotthardt, D. N. (2019) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.15146 · Cited by 17 · see citing works
- Authors
- Chapman, M. H., Thorburn, D., Hirschfield, G. M., Webster, G. G. J., Rushbrook, S. M., Alexander, G., Collier, J., Dyson, J. K., Jones, D. E., Patanwala, I., Thain, C., Walmsley, M., & Pereira, S. P.
- Affiliations
- Royal Free London NHS Foundation Trust (GB)
- University Health Network (CA)
- Norfolk and Norwich University Hospital (GB)
- John Radcliffe Hospital (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Newcastle University (GB)
- University of Liverpool (GB)
- PBC Foundation (GB)
- PSC Support (GB)
- University College London (GB)
- Corresponding author
- Pereira, Stephen P
- ORCID
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2019-06-01
- Volume
- 68
- Issue
- 8
- Pages
- 1356-1378
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC6691863
- OpenAlex
- W2947046480
- Cited by
- 284
- References
- 294
- Citations by year
- 2026: 25 · 2025: 40 · 2024: 44 · 2023: 47 · 2022: 46 · 2021: 43 · 2020: 33 · 2019: 5
- FWCI
- 20.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- UEA Digital Repository (University of East Anglia) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Funders
- National Institute for Health and Care Research (NIHR200243)
- Topics
- Health Sciences › Medicine › Hepatology › Liver Diseases and Immunity
- Health Sciences › Medicine › Surgery › Pediatric Hepatobiliary Diseases and Treatments
- Health Sciences › Medicine › Rheumatology › IgG4-Related and Inflammatory Diseases
- Keywords
- primary sclerosing cholangitis, diagnosis, management, cholangiopathy, patient-centered care
- MeSH terms
- Immunoglobulin G4-Related Disease, Biliary Tract Neoplasms, Diagnosis, Differential, Diagnostic Techniques, Digestive System, United Kingdom, Humans, Patient Care Management, Prognosis, Cholangitis, Sclerosing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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