Cited by 284Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and TreatmentsIgG4-Related and Inflammatory Diseases

British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis

Open access
Chapman, Michael Huw, Thorburn, Douglas, Hirschfield, Gideon M, Webster, George G J, Rushbrook, Simon M, Alexander, Graeme, Collier, Jane, Dyson, Jessica K +5 more·2019·Gut

Abstract

These guidelines on the management of primary sclerosing cholangitis (PSC) were commissioned by the British Society of Gastroenterology liver section. The guideline writing committee included medical representatives from hepatology and gastroenterology groups as well as patient representatives from PSC Support. The guidelines aim to support general physicians, gastroenterologists and surgeons in managing adults with PSC or those presenting with similar cholangiopathies which may mimic PSC, such as IgG4 sclerosing cholangitis. It also acts as a reference for patients with PSC to help them understand their own management. Quality of evidence is presented using the AGREE II format. Guidance is meant to be used as a reference rather than for rigid protocol-based care as we understand that management of patients often requires individual patient-centred considerations.

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Registry

Crossref · 10.1136/gutjnl-2018-317993

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  • MRI/MRC is the best non-invasive tool to assess large bile duct changes in PSC.

    “As universally agreed, MRI/MRC is the best non-invasive tool to assess large bile duct changes in PSC.[20][21][22]”

    From EASL Clinical Practice Guidelines on sclerosing cholangitis (2022) · cites this paper as [22]

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Cites

1 retracted

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Research works printed but not linked: 2

  1. funding from British Liver Trust, PSC Partners, PSC Support, EASL, SMR - Involvement in clinical trials in PSC and sits on the advisory board for FALK and Intercept. GH -medical adviser for PSC Support, speaker fees and educational support from Falk Pharma. on August 2, 2023 by guest. Protected by copyright. http://gut.bmj.com/ Gut: first published as 10.1136/gutjnl-2018-317993 on 1 June 2019. Downloaded from RefeRences
  2. Al Mamari S, Djordjevic J, Halliday JS, et al. Improvement of serum alkaline phosphatase to. J Hepatol 2013;58:329-34.

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Authors
Chapman, M. H., Thorburn, D., Hirschfield, G. M., Webster, G. G. J., Rushbrook, S. M., Alexander, G., Collier, J., Dyson, J. K., Jones, D. E., Patanwala, I., Thain, C., Walmsley, M., & Pereira, S. P.
Affiliations
  • Royal Free London NHS Foundation Trust (GB)
  • University Health Network (CA)
  • Norfolk and Norwich University Hospital (GB)
  • John Radcliffe Hospital (GB)
  • Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
  • Newcastle University (GB)
  • University of Liverpool (GB)
  • PBC Foundation (GB)
  • PSC Support (GB)
  • University College London (GB)
Corresponding author
Pereira, Stephen P
Venue
Gut
Publisher
BMJ
Published
2019-06-01
Volume
68
Issue
8
Pages
1356-1378
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2947046480
Cited by
284
References
294
Citations by year
2026: 25 · 2025: 40 · 2024: 44 · 2023: 47 · 2022: 46 · 2021: 43 · 2020: 33 · 2019: 5
FWCI
20.23
Type
journal article
Language
en
Open access
Locations
  • Gut (publishedVersion)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
  • UEA Digital Repository (University of East Anglia) (submittedVersion)
  • Newcastle University ePrints (Newcastle Univesity)
Funders
National Institute for Health and Care Research (NIHR200243)
Topics
  • Health Sciences › Medicine › Hepatology › Liver Diseases and Immunity
  • Health Sciences › Medicine › Surgery › Pediatric Hepatobiliary Diseases and Treatments
  • Health Sciences › Medicine › Rheumatology › IgG4-Related and Inflammatory Diseases
Keywords
primary sclerosing cholangitis, diagnosis, management, cholangiopathy, patient-centered care
MeSH terms
Immunoglobulin G4-Related Disease, Biliary Tract Neoplasms, Diagnosis, Differential, Diagnostic Techniques, Digestive System, United Kingdom, Humans, Patient Care Management, Prognosis, Cholangitis, Sclerosing

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