Regulation of Homologous Recombination in Eukaryotes

Genome maintenance mechanisms for preventing cancer

Hoeijmakers, J. H. J. (2001) · Nature · doi:10.1038/35077232 · Cited by 3,939

Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae

Pâques, F., & Haber, J. E. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.2.349-404.1999 · Cited by 2,120

Rates of spontaneous mutation

Drake, J. W., Charlesworth, B., Charlesworth, D., & Crow, J. F. (1998) · Genetics · doi:10.1093/genetics/148.4.1667 · Cited by 1,932

Mechanism of Eukaryotic Homologous Recombination

Filippo, J. S., Sung, P., & Klein, H. L. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061306.125255 · Cited by 1,766

Human CtIP promotes DNA end resection

Sartori, A. A., Lukas, C., Coates, J., Mistrik, M., Fu, S., Bartek, J., Baer, R., Lukas, J., & Jackson, S. P. (2007) · Nature · doi:10.1038/nature06337 · Cited by 1,362

Mammalian cyclin-dependent kinases

Malumbres, M., & Barbacid, M. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.09.005 · Cited by 1,333

Regulation of DNA double-strand break repair pathway choice

Shrivastav, M., De Haro, L. P., & Nickoloff, J. A. (2008) · Cell Research · doi:10.1038/cr.2007.111 · Cited by 1,329

Regulation of DNA repair throughout the cell cycle

Branzei, D., & Foiani, M. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2351 · Cited by 1,228

Homologous recombination in DNA repair and DNA damage tolerance

Li, X., & Heyer, W. (2008) · Cell Research · doi:10.1038/cr.2008.1 · Cited by 1,203

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

Zhu, Z., Chung, W.-H., Shim, E. Y., Lee, S. E., & Ira, G. (2008) · Cell · doi:10.1016/j.cell.2008.08.037 · Cited by 1,108

Selenium Toxicity toward Yeast as Assessed by Microarray Analysis and Deletion Mutant Library Screen: A Role for DNA Repair

Mániková, D., Vlasáková, D., Letavayová, L., Klobučnı́ková, V., Griač, P., & Chovanec, M. (2012) · Chemical Research in Toxicology · doi:10.1021/tx300061n · Cited by 22

CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish

Gonzãlez, F. (2016) · Developmental Dynamics · doi:10.1002/dvdy.24414 · Cited by 22

Applications of CRISPR/Cas9 in retinal degenerative diseases

Peng, Y., Tang, L.-S., Yoshida, S., & Zhou, Y. (2017) · International Journal of Ophthalmology · doi:10.18240/ijo.2017.04.23 · Cited by 25

Frequent template switching in postreplication gaps: suppression of deleterious consequences by the Escherichia coli Uup and RadD proteins

Romero, Z. J., Armstrong, T. J., Henrikus, S. S., Chen, S. H., Glass, D. J., Ferrazzoli, A. E., Wood, E. A., Chitteni‐Pattu, S., van Oijen, A. M., Lovett, S. T., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz960 · Cited by 20

Two auxiliary factors promote Dmc1-driven DNA strand exchange via stepwise mechanisms

Tsubouchi, H., Argunhan, B., Ito, K., Takahashi, M., & Iwasaki, H. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1917419117 · Cited by 21

RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis

Sanchez-Rebato, M. H., Bouatta, A. M., Gallego, M. E., White, C., & Ines, O. D. (2020) · bioRxiv · doi:10.1371/journal.pgen.1008919 · Cited by 19

Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing

Vlashi, R., Zhang, X., Li, H., & Chen, G. (2023) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09860-y · Cited by 24

E2F-7 couples DNA damage-dependent transcription with the DNA repair process

Zalmas, L., Coutts, A. S., Helleday, T., & Thangue, N. B. L. (2013) · Cell Cycle · doi:10.4161/cc.26078 · Cited by 22

Is the role of human RNase H2 restricted to its enzyme activity?

Feng, S., & Cao, Z. (2015) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2015.11.001 · Cited by 22

CRISPR‐Cas9: A cornerstone for the evolution of precision medicine

Razzouk, S. (2018) · Annals of Human Genetics · doi:10.1111/ahg.12271 · Cited by 22

A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo

Chien, J. C.-Y., Tabet, E. I., Pinkham, K., da Hora, C. C., Chang, J. C.-Y., Lin, S., Badr, C. E., & Lai, C. P. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa669 · Cited by 21

ATM-dependent activation of SIM2s regulates homologous recombination and epithelial–mesenchymal transition

Pearson, S. J., Sarkar, T. R., McQueen, C. M., Epps, J. L., Schmitt, E. E., Wall, S. W., Scribner, K. C., Wyatt, G. L., Barhoumi, R., Behbod, F., et al. (2018) · Oncogene · doi:10.1038/s41388-018-0622-4 · Cited by 22

Gene therapy for inherited retinal diseases: exploiting new tools in genome editing and nanotechnology

Carvalho, C., Lemos, L., Antas, P., & Seabra, M. C. (2023) · Frontiers in Ophthalmology · doi:10.3389/fopht.2023.1270561 · Cited by 21

Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast

North, M. R., Gaytán, B. D., Romero, C., Rosa, V. Y. D. L., Loguinov, A. V., Smith, M. T., Zhang, L., & Vulpe, C. D. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00200 · Cited by 21

Non-Recombinogenic Functions of Rad51, BRCA2, and Rad52 in DNA Damage Tolerance

Prado, F. (2021) · Genes · doi:10.3390/genes12101550 · Cited by 23

ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition

Bakr, A., Hey, J., Sigismondo, G., Liu, C.-S., Sadik, A., Goyal, A., Cross, A., Iyer, R. L., Müller, P., Trauernicht, M., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab964 · Cited by 24

Single‐strand annealing: Molecular mechanisms and potential applications in CRISPR‐Cas‐based precision genome editing

Vu, T. V., Das, S., Nguyen, C. C., Kim, J., & Kim, J. (2021) · Biotechnology Journal · doi:10.1002/biot.202100413 · Cited by 22

CRISPR/Cas gene editing in the human germline

Bekaert, B., Boel, A., Cosemans, G., Witte, L. D., Menten, B., & Heindryckx, B. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.03.012 · Cited by 21

Development of non-viral vectors for neuronal-targeted delivery of CRISPR-Cas9 RNA-proteins as a therapeutic strategy for neurological disorders

Shalaby, K. E., Aouida, M., Gupta, V., Abdesselem, H., & El‐Agnaf, O. M. A. (2022) · Biomaterials Science · doi:10.1039/d2bm00368f · Cited by 21

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD

Hanson, B., Stenler, S., Ahlskog, N., Chwalenia, K., Svrzikapa, N., Coenen-Stass, A. M. L., Weinberg, M. S., Wood, M. J. A., & Roberts, T. C. (2022) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2022.10.010 · Cited by 18

Break‐induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?

Gómez‐González, B., & Aguilera, A. (2023) · EMBO Reports · doi:10.15252/embr.202357801 · Cited by 23

ATXN3: a multifunctional protein involved in the polyglutamine disease spinocerebellar ataxia type 3

Hernández-Carralero, E., Quinet, G., & Freire, R. (2024) · Expert Reviews in Molecular Medicine · doi:10.1017/erm.2024.10 · Cited by 21

Single-molecule views on homologous recombination

Candelli, A., Modesti, M., Peterman, E. J. G., & Wuite, G. J. L. (2013) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583513000073 · Cited by 21

Long-range heterochromatin association is mediated by silencing and double-strand DNA break repair proteins

Kirkland, J. G., & Kamakaka, R. T. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201211105 · Cited by 21

A Non-Synonymous Single Nucleotide Polymorphism in the HJURP Gene Associated with Susceptibility to Hepatocellular Carcinoma among Chinese

Huang, W., Zhang, H., Hao, Y., Xu, X., Zhai, Y., Wang, S., Li, Y., Ma, F., Li, Y., Wang, Z., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148618 · Cited by 21

Use of CRISPR/Cas9 to model brain diseases

Yan, S., Tu, Z., Li, S., & Li, X. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.04.003 · Cited by 20

The relationship between histone posttranslational modification and DNA damage signaling and repair

Sharma, A. K., & Hendzel, M. J. (2018) · International Journal of Radiation Biology · doi:10.1080/09553002.2018.1516911 · Cited by 20

Synthetic Virus-Derived Nanosystems (SVNs) for Delivery and Precision Docking of Large Multifunctional DNA Circuitry in Mammalian Cells

Aulicino, F., Capin, J., & Berger, I. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12080759 · Cited by 21

Targeted Inter-Homologs Recombination in Arabidopsis Euchromatin and Heterochromatin

Hayut, S. F., Kniazev, K., Melamed‐Bessudo, C., & Levy, A. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212096 · Cited by 21

Nonrandom Distribution of Interhomolog Recombination Events Induced by Breakage of a Dicentric Chromosome inSaccharomyces cerevisiae

Song, W., Gaweł, M., Dominska, M., Greenwell, P. W., Hazkani‐Covo, E., Bloom, K., & Petes, T. D. (2013) · Genetics · doi:10.1534/genetics.113.150144 · Cited by 20

In Silico Screening Identifies a Novel Potential PARP1 Inhibitor Targeting Synthetic Lethality in Cancer Treatment

Li, J., Zhou, N., Cai, P., & Bao, J. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17020258 · Cited by 21

Response and adaptation of Chlorella pyrenoidosa to 6PPD: Physiological and genetic mechanisms

Chen, Y., Lei, Y., Chen, J., Gao, A., Hu, J., Wang, H., & Zhang, X. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.136122 · Cited by 20

Crop Quality Improvement Through Genome Editing Strategy

Yang, Y., Xu, C., Shen, Z., & Yan, C. (2022) · Frontiers in Genome Editing · doi:10.3389/fgeed.2021.819687 · Cited by 20

Interactions between miRNAs and Double-Strand Breaks DNA Repair Genes, Pursuing a Fine-Tuning of Repair

Peraza-Vega, R. I., Valverde, M., & Rojas, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063231 · Cited by 20

Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice

Tsuji, S., Stephens, C. J., Bortolussi, G., Zhang, F., Baj, G., Jang, H., de Alencastro, G., Muro, A. F., Pekrun, K., & Kay, M. A. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01240-2 · Cited by 23

To the Rescue: The Fanconi Anemia Genome Stability Pathway Salvages Replication Forks

Moldovan, G., & D’Andrea, A. D. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.06.006 · Cited by 22

ovoD Co-selection: A Method for Enriching CRISPR/Cas9-Edited Alleles in Drosophila

Ewen‐Campen, B., & Perrimon, N. (2018) · G3 Genes Genomes Genetics · doi:10.1534/g3.118.200498 · Cited by 20

Dynamic interactions of the homologous pairing 2 (Hop2)–meiotic nuclear divisions 1 (Mnd1) protein complex with meiotic presynaptic filaments in budding yeast

Crickard, J. B., Kwon, Y., Sung, P., & Greene, E. C. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.006146 · Cited by 23

Efficient correction of a deleterious point mutation in primary horse fibroblasts with CRISPR-Cas9

Pinzón-Arteaga, C. A., Snyder, M. D., Lazzarotto, C. R., Moreno, N. F., Juras, R., Raudsepp, T., Golding, M. C., Varner, D. D., & Long, C. R. (2020) · Scientific Reports · doi:10.1038/s41598-020-62723-3 · Cited by 21

FOXK1 Participates in DNA Damage Response by Controlling 53BP1 Function

Tang, M., Feng, X., Pei, G., Srivastava, M., Wang, C., Chen, Z., Li, S., Zhang, H., Zhao, Z., Li, X., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108018 · Cited by 21

Multiple Pathways Suppress Non-Allelic Homologous Recombination during Meiosis in Saccharomyces cerevisiae

Shinohara, M., & Shinohara, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063144 · Cited by 20

AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts

Xu, H., Zhou, Y., Coughlan, K. A., Ding, Y., Wang, S., Wu, Y., Song, P., & Zou, M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.10.002 · Cited by 21

LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair

Hirakawa, T., Kuwata, K., Gallego, M. E., White, C. I., Nomoto, M., Tada, Y., & Matsunaga, S. (2019) · PLANT PHYSIOLOGY · doi:10.1104/pp.19.00530 · Cited by 20

Telomere length analysis on leukocytes derived from patients with Huntington Disease

PerezGrovas-Saltijeral, A., Ochoa-Morales, A., Miranda-Duarte, A., Martínez-Ruano, L., Jara-Prado, A., Camacho-Molina, A., & Hidalgo-Bravo, A. (2020) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2019.111189 · Cited by 19

Homologous Recombination Deficiency in Ovarian and Breast Cancers: Biomarkers, Diagnosis, and Treatment

Shah, B. A., Hussain, M. S., & Seth, A. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47080638 · Cited by 28

Application of genome editing technologies to the study and treatment of hematological disease

Pellagatti, A., Dolatshad, H., Yip, B. H., Valletta, S., & Boultwood, J. (2015) · Advances in Biological Regulation · doi:10.1016/j.jbior.2015.09.005 · Cited by 20

Ubiquitylation in DNA double-strand break repair

Tang, M., Li, S., & Chen, J. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103129 · Cited by 24

Interplay between the DNA Damage Response and Immunotherapy Response in Cancer

Lee, E. C. Y., Kok, J. S.-T., Teh, B. T., & Lim, K. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113356 · Cited by 22

Elevated APE1 Dysregulates Homologous Recombination and Cell Cycle Driving Genomic Evolution, Tumorigenesis, and Chemoresistance in Esophageal Adenocarcinoma

Kumar, S., Zhao, J., Talluri, S., Buon, L., Mu, S., Potluri, L. B., Liao, C., Shi, J., Chakraborty, C., Gonzalez, G. B., et al. (2023) · Gastroenterology · doi:10.1053/j.gastro.2023.04.035 · Cited by 18

A Versatile Scaffold Contributes to Damage Survival via Sumoylation and Nuclease Interactions

Sarangi, P., Altmannová, V., Holland, C., Bartošová, Z., Hao, F., Anrather, D., Ammerer, G., Lee, S. E., Krejčí, L., & Zhao, X. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.054 · Cited by 19

Nonsense-mediated decay regulates key components of homologous recombination

Janke, R., Kong, J., Braberg, H., Cantin, G. T., Yates, J. R., Krogan, N. J., & Heyer, W. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw182 · Cited by 19

Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 endonuclease complex are not genetically separable

Jensen, K. L., & Russell, P. R. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw557 · Cited by 19

Rice RAD 51 paralogs play essential roles in somatic homologous recombination for DNA repair

Xu, Z., Zhang, J., Xu, M., Ji, W., Yu, M., Tao, Y., Gong, Z., Gu, M., & Yu, H. (2018) · The Plant Journal · doi:10.1111/tpj.13949 · Cited by 19

Establishment of gene‐edited pigs expressing human blood‐coagulation factor VII and albumin for bioartificial liver use

Li, L., Meng, H., Zou, Q., Zhang, J., Cai, L., Yang, B., Weng, J., Lai, L., Yang, H., & Gao, Y. (2019) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14666 · Cited by 19

Evaluation of DNA double-strand break repair capacity in human cells: Critical overview of current functional methods

Tatin, X., Muggiolu, G., Sauvaigo, S., & Breton, J. (2021) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2021.108388 · Cited by 19

Mismatch repair disturbs meiotic class I crossover controlPreprint

Cooper, T. J., Crawford, M. R., Hunt, L. J., Marsolier‐Kergoat, M., Llorente, B., & Neale, M. J. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/480418 · Cited by 19

Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks

Davé, A., Pai, C., Durley, S. C., Hulme, L., Sarkar, S., Wee, B.-Y., Prudden, J., Tinline-Purvis, H., Cullen, J. K., Walker, C. A., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz1109 · Cited by 18

Beta Human Papillomavirus 8E6 Attenuates Non-Homologous End Joining by Hindering DNA-PKcs Activity

Hu, C., Bugbee, T., Gamez, M., & Wallace, N. A. (2020) · Cancers · doi:10.3390/cancers12092356 · Cited by 21

Generation and Repair of Postreplication Gaps in Escherichia coli

Cox, M. M., Goodman, M. F., Keck, J. L., van Oijen, A. M., Lovett, S. T., & Robinson, A. (2023) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00078-22 · Cited by 18

The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations

Pallaseni, A., Peets, E. M., Girling, G., Crepaldi, L., Kuzmin, I., Moor, M., Muñoz-Subirana, N., Schimmel, J., Serçin, Ö., Mardin, B. R., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54566-7 · Cited by 18

Therapeutic Intervention by the Simultaneous Inhibition of DNA Repair and Type I or Type II DNA Topoisomerases: One Strategy, Many Outcomes

Węsierska‐Gądek, J., & Składanowski, A. (2011) · Future Medicinal Chemistry · doi:10.4155/fmc.11.175 · Cited by 17

Leishmania major and Trypanosoma cruzi present distinct DNA damage responses

Garcia, J. B. F., Vieira‐da‐Rocha, J. P., Costa-Silva, H. M., Alves, C. L., Machado, C. R., & Cruz, Â. K. (2016) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2016.05.004 · Cited by 18

CRISPR/Cas9 therapeutics for liver diseases

Aravalli, R. N., & Steer, C. J. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26627 · Cited by 19

Immunotherapy perspectives in the new era of B-cell editing

Ueda, N., Cahen, M., Danger, Y., Moreaux, J., Sirac, C., & Cogné, M. (2021) · Blood Advances · doi:10.1182/bloodadvances.2020003792 · Cited by 19

Generation of targeted mouse mutants by embryo microinjection of TALENs

Wefers, B., Ortiz, O., Wurst, W., & Kühn, R. (2014) · Methods · doi:10.1016/j.ymeth.2014.01.002 · Cited by 18

The Role of Gene Editing in Neurodegenerative Diseases

Fan, H.-C., Chi, C.-S., Lee, Y.-J., Tsai, J., Lin, S., & Harn, H.-J. (2018) · Cell Transplantation · doi:10.1177/0963689717753378 · Cited by 18

Principles of gene editing techniques and applications in animal husbandry

Jiang, S., & Shen, Q. W. (2019) · 3 Biotech · doi:10.1007/s13205-018-1563-x · Cited by 18

CRISPR/Cas: An intriguing genomic editing tool with prospects in treating neurodegenerative diseases

Rahman, S., Datta, M., Kim, J., & Jan, A. T. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.05.014 · Cited by 19

FANCJ helicase controls the balance between short- and long-tract gene conversions between sister chromatids

Nath, S., Somyajit, K., Mishra, A., Scully, R., & Nagaraju, G. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx586 · Cited by 17

Targeting Defects in the Cellular DNA Damage Response for the Treatment of Pancreatic Ductal Adenocarcinoma

Schmitt, A., Feldmann, G., Zander, T., & Reinhardt, H. C. (2018) · Oncology Research and Treatment · doi:10.1159/000493401 · Cited by 18

Application of genome-editing systems to enhance available pig resources for agriculture and biomedicine

Lee, K., Farrell, K., & Uh, K. (2019) · Reproduction Fertility and Development · doi:10.1071/rd19273 · Cited by 18

多样化CRISPR技术在动物体内基因编辑研究中的应用和进展

马迅, Ma, X., 黄芯渝, 谭晞彦, 崔雍建, 钟礼瞬, 冯波, Wong, A. S.-Y., Tam, H.-Y., Tsui, S. Y.-K., et al. (2018) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2017.012 · Cited by 17

Human SIRT2 and SIRT3 deacetylases function in DNA homologous recombinational repair

Yasuda, T., Takizawa, K., Ui, A., Hama, M., Kagawa, W., Sugasawa, K., & Tajima, K. (2021) · Genes to Cells · doi:10.1111/gtc.12842 · Cited by 18

Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside–Nucleoside Analogue Radiosensitization

Magin, S., Papaioannou, M., Saha, J., Staudt, C., & Iliakis, G. E. (2015) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-14-0682 · Cited by 17

Single-Molecule DNA Analysis Reveals That Yeast Hop1 Protein Promotes DNA Folding and Synapsis: Implications for Condensation of Meiotic Chromosomes

Khan, K., Karthikeyan, U., Li, Y., Yan, J., & Muniyappa, K. (2012) · ACS Nano · doi:10.1021/nn3038258 · Cited by 17

DNA Double Strand Break Repair - Related Synthetic Lethality

Toma, M. M., Skórski, T., & Śliwiński, T. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180201114306 · Cited by 17

New Directions in Pulmonary Gene Therapy

Vu, A., & McCray, P. B. (2020) · Human Gene Therapy · doi:10.1089/hum.2020.166 · Cited by 19

Dual regulation of Dmc1-driven DNA strand exchange by Swi5–Sfr1 activation and Rad22 inhibitionPreprint

Murayama, Y., Kurokawa, Y., Tsutsui, Y., & Iwasaki, H. (2013) · Genes & Development · doi:10.1101/gad.218693.113 · Cited by 17

Precise base editing without unintended indels in human cells and mouse primary myoblasts

Yoon, D. E., Kim, N., Park, S.-J., Jeong, T. Y., Eun, B., Cho, Y., Lim, S., Lee, H., Seong, J. K., & Kim, K. (2023) · Experimental & Molecular Medicine · doi:10.1038/s12276-023-01128-4 · Cited by 15

Impact of Manganese and Chromate on Specific DNA Double-Strand Break Repair Pathways

Haberland, V. M. M., Magin, S., Iliakis, G. E., & Hartwig, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210392 · Cited by 16

CRISPR/Cas9 as a Mutagenic Factor

Shumega, A. R., Pavlov, Y. I., Chirinskaite, A. V., Rubel, A. A., Inge-Vechtomov, S. G., & Stepchenkova, E. I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25020823 · Cited by 18

Genome editing and its role in vaccine, diagnosis, and therapeutic advancement

Bisht, D., Salave, S., Desai, N., Gogoi, P., Rana, D., Biswal, P., Sarma, G., Benival, D. M., Kommineni, N., & Desai, D. N. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.131802 · Cited by 16

Genome editing: An insight into disease resistance, production efficiency, and biomedical applications in livestock

Yuan, Y., Liu, S.-Z., Farhab, M., Lv, M.-Y., Zhang, T., & Cao, S.-X. (2024) · Functional & Integrative Genomics · doi:10.1007/s10142-024-01364-5 · Cited by 18

The GATAD2B-NuRD complex drives DNA:RNA hybrid-dependent chromatin boundary formation upon DNA damage

Liu, Z., Ajit, K., Wu, Y., Zhu, W., & Gullerová, M. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00111-7 · Cited by 16

Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries

Payero, L., & Alani, E. (2024) · Trends in Genetics · doi:10.1016/j.tig.2024.09.009 · Cited by 17

The Role of Blm Helicase in Homologous Recombination, Gene Conversion Tract Length, and Recombination Between Diverged Sequences in Drosophila melanogaster

Ertl, H. A., Russo, D., Srivastava, N., Brooks, J. T., Dao, T. N., & LaRocque, J. R. (2017) · Genetics · doi:10.1534/genetics.117.300285 · Cited by 16

Histone chaperone ASF1 acts with RIF1 to promote DNA end joining in BRCA1-deficient cells

Tang, M., Chen, Z., Wang, C., Feng, X., Lee, N., Huang, M., Zhang, H., Li, S., Xiong, Y., & Chen, J. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.101979 · Cited by 16

Functional Relationship of ATP Hydrolysis, Presynaptic Filament Stability, and Homologous DNA Pairing Activity of the Human Meiotic Recombinase DMC1

Chang, H.-Y., Liao, C.-Y., Su, G.-C., Lin, S., Wang, H., & Chi, P. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.666289 · Cited by 16

Physical and genetic-interaction density reveals functional organization and informs significance cutoffs in genome-wide screens

Dittmar, J. C., Pierce, S. E., Rothstein, R. J., & Reid, R. J. D. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219582110 · Cited by 16

I-SceI enzyme mediated integration (SEMI) for fast and efficient gene targeting in Trichoderma reesei

Ouedraogo, J., Arentshorst, M., Nikolaev, I., Barends, S., & Ram, A. F. J. (2016) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2016.02.012 · Cited by 16

The spindle assembly checkpoint: More than just keeping track of the spindle.

Lawrence, K. S., & Engebrecht, J. (2015) · PubMed · Cited by 16

Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinasesPreprint

Anzalone, A. V., Gao, X. D., Podracky, C. J., Nelson, A. T., Koblan, L. W., Raguram, A., Levy, J. M., Mercer, J. A. M., & Liu, D. R. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.11.01.466790 · Cited by 16

Gene Editing to Tackle Facioscapulohumeral Muscular Dystrophy

Mariot, V., & Dumonceaux, J. (2022) · Frontiers in Genome Editing · doi:10.3389/fgeed.2022.937879 · Cited by 16

The function and evolution of a genetic switch controlling sexually dimorphic eye differentiation in honeybees

Netschitailo, O., Wang, Y., Wagner, A., Sommer, V., Verhulst, E. C., & Beye, M. (2023) · Nature Communications · doi:10.1038/s41467-023-36153-4 · Cited by 16

GMP-manufactured CRISPR/Cas9 technology as an advantageous tool to support cancer immunotherapy

Caforio, M., Iacovelli, S., Quintarelli, C., Locatelli, F., & Folgiero, V. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-02993-1 · Cited by 15

Upregulation of RAD51 expression is associated with progression of thyroid carcinoma

Sarwar, R., Sheikh, A. K., Mahjabeen, I., Bashir, K., Saeed, S., & Kayani, M. A. (2017) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2017.05.001 · Cited by 15

Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells

Salisbury-Ruf, C. T., & Larochelle, A. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10030513 · Cited by 15

Genetic instability is prevented by Mrc1‐dependent spatio‐temporal separation of replicative and repair activities of homologous recombination

Prado, F. (2014) · BioEssays · doi:10.1002/bies.201300161 · Cited by 17

Alteration of genetic recombination and double-strand break repair in human cells by progerin expression

Komari, C. J., Guttman, A. O., Carr, S. R., Trachtenberg, T. L., Orloff, E. A., Haas, A. V., Patrick, A. R., Chowdhary, S., Waldman, B. C., & Waldman, A. S. (2020) · DNA repair · doi:10.1016/j.dnarep.2020.102975 · Cited by 17

Engineering delivery platforms for CRISPR-Cas and their applications in healthcare, agriculture and beyond

Bharti, N., Modi, U., Bhatia, D. D., & Solanki, R. (2026) · Nanoscale Advances · doi:10.1039/d5na00535c · Cited by 15

Homologous Recombination in Mammals

Barascu, A., Grabarz, A., & López, B. S. (2012) · Topics in current genetics · doi:10.1007/978-94-007-4531-5_4 · Cited by 1

Homologous Recombination in Eukaryotes

Amunugama, R., & Fishel, R. A. (2012) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-387665-2.00007-9 · Cited by 39

Mechanism and significance of chromosome damage repair by homologous recombination

Kawale, A. S., & Sung, P. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190093 · Cited by 33

Homologous recombination in mammalian cells: From molecular mechanisms to pathology

Ragu, S., Matos-Rodrigues, G. E., THOMAS, M. L., & López, B. S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85679-9.00020-9 · Cited by 2

SURVEY AND SUMMARY Homologous recombination and its regulation

Krejčí, L., Altmannová, V., Špı́rek, M., & Zhao, X. (2012)