Regulation of Homologous Recombination in Eukaryotes

Genome maintenance mechanisms for preventing cancer

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Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae

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Rates of spontaneous mutation

Drake, J. W., Charlesworth, B., Charlesworth, D., & Crow, J. F. (1998) · Genetics · doi:10.1093/genetics/148.4.1667 · Cited by 1,932

Mechanism of Eukaryotic Homologous Recombination

Filippo, J. S., Sung, P., & Klein, H. L. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061306.125255 · Cited by 1,766

Human CtIP promotes DNA end resection

Sartori, A. A., Lukas, C., Coates, J., Mistrik, M., Fu, S., Bartek, J., Baer, R., Lukas, J., & Jackson, S. P. (2007) · Nature · doi:10.1038/nature06337 · Cited by 1,362

Mammalian cyclin-dependent kinases

Malumbres, M., & Barbacid, M. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.09.005 · Cited by 1,333

Regulation of DNA double-strand break repair pathway choice

Shrivastav, M., De Haro, L. P., & Nickoloff, J. A. (2008) · Cell Research · doi:10.1038/cr.2007.111 · Cited by 1,329

Regulation of DNA repair throughout the cell cycle

Branzei, D., & Foiani, M. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2351 · Cited by 1,228

Homologous recombination in DNA repair and DNA damage tolerance

Li, X., & Heyer, W. (2008) · Cell Research · doi:10.1038/cr.2008.1 · Cited by 1,203

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

Zhu, Z., Chung, W.-H., Shim, E. Y., Lee, S. E., & Ira, G. (2008) · Cell · doi:10.1016/j.cell.2008.08.037 · Cited by 1,108

Speciation and adaptation research meets genome editing

Ansai, S., & Kitano, J. (2022) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2020.0516 · Cited by 16

Characterization of the interactome profiling of Mycoplasma fermentans DnaK in cancer cells reveals interference with key cellular pathways

Curreli, S., Benedetti, F., Yuan, W., Munawwar, A., Cocchi, F., Gallo, R. C., Sherman, N. E., & Zella, D. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1022704 · Cited by 14

Clinical and Therapeutic Evaluation of the Ten Most Prevalent CRB1 Mutations

da Costa, B. L., Kolesnikova, M., Levi, S. R., Cabral, T., Tsang, S. H., Maumenee, I. H., & Quinn, P. M. J. (2023) · Biomedicines · doi:10.3390/biomedicines11020385 · Cited by 15

High-efficiency targeted transgene integration via primed micro-homologues

Wang, C., Fang, S., Chen, Y., Tang, N., Jiao, G., Hu, Y., Li, J., Shan, Q., Wang, X., Feng, G., et al. (2023) · Cell Discovery · doi:10.1038/s41421-023-00552-0 · Cited by 14

Targeting Polymerase Theta (POLθ) for Cancer Therapy

Patterson-Fortin, J., & D’Andrea, A. D. (2023) · Cancer treatment and research · doi:10.1007/978-3-031-30065-3_15 · Cited by 16

Rad59 regulates association of Rad52 with DNA double‐strand breaks

Pannunzio, N. R., Manthey, G. M., Liddell, L. C., Fu, B. X. H., Roberts, C. M., & Bailis, A. M. (2012) · MicrobiologyOpen · doi:10.1002/mbo3.31 · Cited by 14

Essential Domains ofSchizosaccharomyces pombeRad8 Required for DNA Damage Response

Ding, L., & Forsburg, S. L. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.011346 · Cited by 14

CRISPR-Mediated Ophthalmic Genome Surgery

Cho, G. Y., Abdulla, Y. L., Sengillo, J. D., Justus, S., Schaefer, K. A., Bassuk, A. G., Tsang, S. H., & Mahajan, V. B. (2017) · Current Ophthalmology Reports · doi:10.1007/s40135-017-0144-1 · Cited by 14

Inhibitors of DNA double-strand break repair at the crossroads of cancer therapy and genome editing

Ray, U., & Raghavan, S. C. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114195 · Cited by 14

Age-associated deficient recruitment of 53BP1 in G1 cells directs DNA double-strand break repair to BRCA1/CtIP-mediated DNA-end resection

Anglada, T., Genescà, A., & Martı́n, M. (2020) · Aging · doi:10.18632/aging.202419 · Cited by 14

Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells

Carley, A. C., Jalan, M., Subramanyam, S., Roy, R., Borgstahl, G. E. O., & Powell, S. N. (2021) · Molecular and Cellular Biology · doi:10.1128/mcb.00524-21 · Cited by 13

Development and expansion of the CRISPR/Cas9 toolboxes for powerful genome engineering in yeast

Guang, C., Lin, Z., & Shi, S. (2022) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2022.110056 · Cited by 14

Analysis of BRCT5 domain-containing proteins reveals a new component of DNA damage repair in Arabidopsis

Vladejić, J., Yang, F., Tomaštíková, E. D., Doležel, J., Palecek, J. J., & Pečinka, A. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.1023358 · Cited by 13

The RecA-directed recombination pathway of natural transformation initiates at chromosomal replication forks in the pneumococcus

Johnston, C., Hope, R., Soulet, A., Dewailly, M., Lemos, D. D., & Polard, P. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2213867120 · Cited by 14

Telomere Maintenance in Organisms without Telomerase

James, M., Hemakumar, M., & Capkova, R. (2011) · InTech eBooks · doi:10.5772/19348 · Cited by 15

Mutator Phenotype and DNA Double-Strand Break Repair in BLM Helicase-Deficient Human Cells

Suzuki, T., Yasui, M., & Honma, M. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.00443-16 · Cited by 14

Women’s cancers: how the discovery of BRCA genes is driving current concepts of cancer biology and therapeutics

Murthy, P., & Muggia, F. M. (2019) · ecancermedicalscience · doi:10.3332/ecancer.2019.904 · Cited by 19

CNOT6: A Novel Regulator of DNA Mismatch Repair

Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, D., Duan, S., de Wind, N., Ye, Z., Vakhrushev, S. Y., Scheibye‐Knudsen, M., et al. (2022) · Cells · doi:10.3390/cells11030521 · Cited by 13

SIAH2 regulates DNA end resection and replication fork recovery by promoting CtIP ubiquitination

Jeong, S.-Y., Hariharasudhan, G., Kim, M., Lim, J., Jung, S. M., Choi, E.-J., Chang, I. Y., Kee, Y., You, H. J., & Lee, J.-H. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac808 · Cited by 13

NUDT16 regulates CtIP PARylation to dictate homologous recombination repair

Zhang, Z., Samsa, W. E., & Gong, Z. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae064 · Cited by 13

RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes

Dixit, S., Nagraj, T., Bhattacharya, D., Saxena, S., Sahoo, S., Chittela, R. K., Somyajit, K., & Nagaraju, G. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114594 · Cited by 12

A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair

Phùng, H. T. T., Nguyen, T. A., Munashingha, P. R., Kwon, B., Van, Q. D., & Seo, Y. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv025 · Cited by 13

DNA double-strand break repair in mammals

Raghavan, S., & Pandey, M. (2017) · Journal of Radiation and Cancer Research · doi:10.4103/jrcr.jrcr_18_17 · Cited by 13

Lack of superoxide dismutase in a rad51 mutant exacerbates genomic instability and oxidative stress-mediated cytotoxicity in Saccharomyces cerevisiae

Choi, J. E., Heo, S.-H., Kim, M. J., & Chung, W. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.015 · Cited by 13

Essential Roles for Polymerase Theta-Mediated End Joining in Repair of Chromosome Breaks

Wyatt, D. W. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/5jdw-e446 · Cited by 13

Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum

Küçükyıldırım, S., Behringer, M. G., Sung, W., Brock, D. A., Doak, T. G., Mergen, H., Queller, D. C., Strassmann, J. E., & Lynch, M. (2020) · G3 Genes Genomes Genetics · doi:10.1534/g3.120.401578 · Cited by 12

Expanding the Editing Window of Cytidine Base Editors With the Rad51 DNA-Binding Domain in Rice

Wei, C., Liu, H., Wang, W., Luo, P., Chen, Q., Li, R., Wang, C., Botella, J. R., & Zhang, H. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.865848 · Cited by 13

The MRN complex and topoisomerase IIIa–RMI1/2 synchronize DNA resection motor proteins

Soniat, M. M., Nguyen, G., Kuo, H., & Finkelstein, I. J. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102802 · Cited by 13

Recombination products suggest the frequent occurrence of aberrant gene replacement in the moss Physcomitrella patens

Wendeler, E., Zobell, O., Chrost, B., & Reiss, B. (2014) · The Plant Journal · doi:10.1111/tpj.12749 · Cited by 13

Application of CRISPR-Cas system in gene therapy: Pre-clinical progress in animal model

Guan, L., Han, Y., Zhu, S., & Lin, J. (2016) · DNA repair · doi:10.1016/j.dnarep.2016.07.004 · Cited by 13

Increased levels of RECQ5 shift DNA repair from canonical to alternative pathways

Olson, H., Davis, L., Kiianitsa, K., Khoo, K. J., Liu, Y., Knijnenburg, T., & Maizels, N. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky727 · Cited by 13

Controlling the balance between chromosome break repair pathways

Jimeno, S., Mejías-Navarro, F., Prados‐Carvajal, R., & Huertas, P. (2018) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2018.10.004 · Cited by 17

Homology-independent multiallelic disruption via CRISPR/Cas9-based knock-in yields distinct functional outcomes in human cells

Zhang, C., He, X., Kwok, Y. K. Y., Wang, F., Xue, J., Zhao, H., Suen, K. W., Wang, C. C., Ren, J., Chen, G. G., et al. (2018) · BMC Biology · doi:10.1186/s12915-018-0616-2 · Cited by 13

Cell and Gene Therapies for Mucopolysaccharidoses: Base Editing and Therapeutic Delivery to the CNS

Christensen, C. L., Ashmead, R. E., & Choy, F. Y. M. (2019) · Diseases · doi:10.3390/diseases7030047 · Cited by 13

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools

Fox, K., Rallapalli, K. L., & Komor, A. C. (2020) · Genes · doi:10.3390/genes11010088 · Cited by 13

Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells

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DNA double-strand break genetic variants in patients with premature ovarian insufficiency

Ding, X., Gong, X., Fan, Y., Cao, J., Zhao, J., Zhang, Y., Wang, X., & Meng, K. (2023) · Journal of Ovarian Research · doi:10.1186/s13048-023-01221-2 · Cited by 15

WD Repeat and HMG Box DNA Binding Protein 1: An Oncoprotein at the Hub of Tumorigenesis and a Novel Therapeutic Target

Zhang, Z., & Zhu, Q. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512494 · Cited by 13

The separation pin distinguishes the pro– and anti–recombinogenic functions of Saccharomyces cerevisiae Srs2

Meir, A., Raina, V. B., Rivera, C. E., Marie, L., Symington, L. S., & Greene, E. C. (2023) · Nature Communications · doi:10.1038/s41467-023-43918-4 · Cited by 14

Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation

Chadda, R., Kaushik, V., Ahmad, I. M., Deveryshetty, J., Holehouse, A. S., Sigurdsson, S. T., Biswas, G., Levy, Y., Bothner, B. B., Cooley, R. B., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae584 · Cited by 12

CRISPR/Cas9-based knockout pipeline for reverse genetics in mammalian cell culture

Spiegel, A., Bachmann, M., Jiménez, G. J., & Sarov, M. (2019) · Methods · doi:10.1016/j.ymeth.2019.04.016 · Cited by 12

The Importance of ATM and ATR in Physcomitrella patens DNA Damage Repair, Development, and Gene Targeting

Martens, M., Horres, R., Wendeler, E., & Reiss, B. (2020) · Genes · doi:10.3390/genes11070752 · Cited by 12

Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells

Benitez, E. K., Lomova, A., Cervantes, L., Clark, D. N., Ayoub, P. G., Senadheera, S., Osborne, K. S., Sanchez, J. M., Crisostomo, R. V., Wang, X., et al. (2020) · Frontiers in Genome Editing · doi:10.3389/fgeed.2020.601541 · Cited by 13

Take a Break to Repair: A Dip in the World of Double-Strand Break Repair Mechanisms Pointing the Gaze on Archaea

Falco, M. D., & Felice, M. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413296 · Cited by 16

N-Terminal Disordered Domain of Saccharomyces cerevisiae Hop1 Protein Is Dispensable for DNA Binding, Bridging, and Synapsis of Double-Stranded DNA Molecules But Is Necessary for Spore Formation

Khan, K., Madhavan, T. P. V., Kshirsagar, R., Boosi, K. N., Sadhale, P. P., & Muniyappa, K. (2013) · Biochemistry · doi:10.1021/bi4005528 · Cited by 12

Dss1 Release Activates DNA Binding Potential in Brh2

Zhou, Q., Kojić, M., & Holloman, W. K. (2012) · Biochemistry · doi:10.1021/bi3011187 · Cited by 12

Activation of DNA Damage Response Induced by the Kaposi’s Sarcoma-Associated Herpes Virus

Domenico, E. G. D., Toma, L., Bordignon, V., Trento, E., D’Agosto, G., Cordiali‐Fei, P., & Ensoli, F. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060854 · Cited by 12

Cleavage of Ku80 by caspase-2 promotes non-homologous end joining-mediated DNA repair

Yan, Q., Zhu, H., Lan, L., Yi, J., & Yang, J. (2017) · DNA repair · doi:10.1016/j.dnarep.2017.10.001 · Cited by 12

PARI functions as a new transcriptional target of FOXM1 involved in gastric cancer development

Zhang, Y., Ye, X.-J., Chen, L., Wu, Q., Gao, Y., & Li, Y. (2018) · International Journal of Biological Sciences · doi:10.7150/ijbs.23945 · Cited by 12

Enhanced homologous recombination by the modulation of targeting vector ends

Hirotsune, S., Kiyonari, H., Jin, M., Kumamoto, K., Yoshida, K., Shinohara, M., Watanabe, H., Wynshaw-Boris, A. J., & Matsuzaki, F. (2020) · Scientific Reports · doi:10.1038/s41598-020-58893-9 · Cited by 12

Microcephaly family protein MCPH1 stabilizes RAD51 filaments

Chang, H.-Y., Lee, C., Lu, C., Lee, W., Yang, H., Yeh, H., Li, H., & Chi, P. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa636 · Cited by 12

Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination

Deveryshetty, J., Mistry, A., Pangeni, S., Ghoneim, M., Tokmina‐Lukaszewska, M., Gore, S. K., Liu, J., Kaushik, V., Karunakaran, S., Taddei, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61811-0 · Cited by 12

Pds5A and Pds5B Display Non-redundant Functions in Mitosis and Their Loss Triggers Chk1 Activation

Al-Jomah, N. A., Mukololo, L., Anjum, A., Madadha, M. E. A., & Patel, R. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00531 · Cited by 11

Recent advancements in CRISPR-Cas toolbox for imaging applications

Singh, V., & Jain, M. (2021) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2021.1950608 · Cited by 11

Comparison of PARPi efficacy according to homologous recombination deficiency biomarkers in patients with ovarian cancer: a systematic review and meta-analysis

Batalini, F., da Silva, L. L., Campoverde, L., Comini, A. C. M., Carvalho, B. M., Nogueira, W., Silveira, H. C. A., Ernst, B. J., & Mina, L. A. (2023) · Chinese Clinical Oncology · doi:10.21037/cco-22-114 · Cited by 12

The biological principles and advanced applications of DSB repair in CRISPR-mediated yeast genome editing

Bai, W., Huang, M., Li, C., & Li­, ­. (2023) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2023.08.007 · Cited by 10

Optimizing CRISPR/Cas9 approaches in the polymorphic tunicate Ciona intestinalis

Pennati, A., Jakobi, M., Zeng, F., Ciampa, L., & Rothbächer, U. (2024) · Developmental Biology · doi:10.1016/j.ydbio.2024.03.003 · Cited by 11

Chronic low‐dose chromium VI exposure induces oxidative stress and apoptosis with altered expressions of DNA repair genes and promoter hypermethylation in the liver of Swiss albino mice

Islam, S., Sarkar, O., Mukherjee, S., Kamila, S., Bhowmik, A. D., & Chattopadhyay, A. (2024) · Journal of Applied Toxicology · doi:10.1002/jat.4600 · Cited by 13

Chromosome Preference During Homologous Recombination Repair of DNA Double-Strand Breaks inDrosophila melanogaster

Fernandez, J., Bloomer, H., Kellam, N., & LaRocque, J. R. (2019) · G3 Genes Genomes Genetics · doi:10.1534/g3.119.400607 · Cited by 11

CDK6 inhibition targeted by miR-378a-3p protects against intestinal injury induced by ionizing radiation

Chu, X., Zheng, W., Wang, J., Zhang, J., Pan, Y., & Shao, C. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.07.093 · Cited by 11

Collaborations between chromatin and nuclear architecture to optimize DNA repair fidelity

Mackenroth, B., & Alani, E. (2020) · DNA repair · doi:10.1016/j.dnarep.2020.103018 · Cited by 11

A Living Organism in your CRISPR Toolbox: Caenorhabditis elegans Is a Rapid and Efficient Model for Developing CRISPR-Cas Technologies

Vicencio, J., & Cerón, J. (2021) · The CRISPR Journal · doi:10.1089/crispr.2020.0103 · Cited by 12

Small-molecule enhancers of CRISPR-induced homology-directed repair in gene therapy: A medicinal chemist’s perspective

Lee, A. B. C., Tan, M. H., & Chai, C. L. L. (2022) · Drug Discovery Today · doi:10.1016/j.drudis.2022.06.006 · Cited by 13

Strategies to improve homology-based repair outcomes following CRISPR-based gene editing in mosquitoes: lessons in how to keep any repair disruptions local

Finney, M., Romanowski, J. S., & Adelman, Z. N. (2022) · Virology Journal · doi:10.1186/s12985-022-01859-2 · Cited by 11

CRISPR-Based Tools for Fighting Rare Diseases

Li, Q., Gao, Y., & Wang, H. (2022) · Life · doi:10.3390/life12121968 · Cited by 11

A Rehabilitation Walker with a Standing Assistance Device

Chugo, D., & Takase, K. (2009) · InTech eBooks · doi:10.5772/7390 · Cited by 11

Nascent DNA Synthesis During Homologous Recombination Is Synergistically Promoted by the Rad51 Recombinase and DNA Homology

Mundia, M. M., Desai, V., Magwood, A. C., & Baker, M. D. (2014) · Genetics · doi:10.1534/genetics.114.161455 · Cited by 12

A Single-Molecule View of Genome Editing Proteins: Biophysical Mechanisms for TALEs and CRISPR/Cas9

Cuculis, L., & Schroeder, C. M. (2017) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-060816-101603 · Cited by 12

New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells

He, X., Li, Y., & Feng, B. (2018) · Stem Cells International · doi:10.1155/2018/9465028 · Cited by 11

Distinct Functions in Regulation of Meiotic Crossovers for DNA Damage Response Clamp Loader Rad24(Rad17) and Mec1(ATR) Kinase

Shinohara, M., Bishop, D. K., & Shinohara, A. (2019) · Genetics · doi:10.1534/genetics.119.302427 · Cited by 11

Disassembly of the Shieldin Complex by TRIP13

Sarangi, P., Clairmont, C. S., & D’Andrea, A. D. (2020) · Cell Cycle · doi:10.1080/15384101.2020.1758435 · Cited by 13

Beta human papillomavirus 8 E6 allows colocalization of non-homologous end joining and homologous recombination repair factors

Hu, C., Bugbee, T., Dacus, D., Palinski, R. M., & Wallace, N. A. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010275 · Cited by 13

Polycomb‐group histone methyltransferase CLF is required for proper somatic recombination in Arabidopsis

Chen, N., Zhou, W., Wang, Y., Dong, A., & Yu, Y. (2014) · Journal of Integrative Plant Biology · doi:10.1111/jipb.12157 · Cited by 11

Relaxed Chromatin Formation and Weak Suppression of Homologous Pairing by the Testis-Specific Linker Histone H1T

Machida, S., Hayashida, R., Takaku, M., Fukuto, A., Sun, J., Kinomura, A., Tashiro, S., & Kurumizaka, H. (2016) · Biochemistry · doi:10.1021/acs.biochem.5b01126 · Cited by 11

Roles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities

Gómez‐Escoda, B., & Wu, P.-Y. J. (2017) · Genes · doi:10.3390/genes8030105 · Cited by 11

Stable Nuclei of Nucleoprotein Filament and High ssDNA Binding Affinity Contribute to Enhanced RecA E38K Recombinase Activity

Lu, C., Chang, T.-T., Cho, C.-C., Lin, H.-C., & Li, H. (2017) · Scientific Reports · doi:10.1038/s41598-017-15088-z · Cited by 11

Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts

Tian, X., Liu, C., Wang, X., Wang, F., Wang, L., Xu, L., Ma, J., Gao, Y., Bao, Y., Wang, F., et al. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0362-y · Cited by 11

A predictive chromatin architecture nexus regulates transcription and DNA damage repair

Bhat, A., Bhan, S., Kabiraj, A., PANDITA, R. K., Ramos, K. S., Nandi, S., Sopori, S., Sarkar, P. S., Dhar, A., Pandita, S., et al. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.108300 · Cited by 12

Regulation of mitotic chromosome architecture and resolution of ultrafine anaphase bridges by PICH

Chanboonyasitt, P., & Chan, Y. W. (2021) · Cell Cycle · doi:10.1080/15384101.2021.1970877 · Cited by 10

Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System

Wefers, B., Wurst, W., & Kühn, R. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2990-1_8 · Cited by 12

Structural and mechanistic insights into the MCM8/9 helicase complex

Weng, Z., Zheng, J., Zhou, Y., Lu, Z., Wu, Y., Xu, D., Li, H., Liang, H., & Liu, Y. (2023) · eLife · doi:10.7554/elife.87468.3 · Cited by 10

SUMO Wrestles with Recombination

Altmannová, V., Kolesár, P., & Krejčí, L. (2012) · Biomolecules · doi:10.3390/biom2030350 · Cited by 12

Intrachromosomal recombination between highly diverged DNA sequences is enabled in human cells deficient in Bloom helicase

Wang, Y., Shen, L., Smith, K., Waldman, B. C., & Waldman, A. S. (2016) · DNA repair · doi:10.1016/j.dnarep.2016.03.005 · Cited by 10

DNA Metabolism in Balance: Rapid Loss of a RecA-Based Hyperrec Phenotype

Bakhlanova, I. V., Dudkina, A. V., Wood, E. A., Lanzov, V. A., Cox, M. M., & Baitin, D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154137 · Cited by 10

RAD51 paralogs promote genomic integrity and chemoresistance in cancer by facilitating homologous recombination

Harris, J. L., Rabellino, A., & Khanna, K. K. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.12.30 · Cited by 10

Gene editing and modulation for Duchenne muscular dystrophy

Stephenson, A. A., & Flanigan, K. M. (2021) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2021.01.029 · Cited by 10

Dual DNA-binding domains shape the interaction of Brh2 with DNA

Zhou, Q., & Holloman, W. K. (2014) · DNA repair · doi:10.1016/j.dnarep.2014.07.013 · Cited by 10

Remodeling and Control of Homologous Recombination by DNA Helicases and Translocases that Target Recombinases and Synapsis

Northall, S. J., Ivančić-Baće, I., Soultanas, P., & Bolt, E. L. (2016) · Genes · doi:10.3390/genes7080052 · Cited by 11

Assaying Repair at DNA Nicks

Davis, L., Zhang, Y., & Maizels, N. (2018) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2017.12.001 · Cited by 10

Association of Promoter Polymorphisms in Xrcc2 Gene Involved in DNA Double Strand Break Repair and Increased Susceptibility to Thyroid Cancer Risk in Pakistani Population

Sarwar, R., & Bashir, K. (2016) · Journal of Carcinogenesis & Mutagenesis · doi:10.4172/2157-2518.1000265 · Cited by 8

Advances in the role of long non‑coding RNAs and RNA‑binding proteins in regulating DNA damage repair in cancer cells

Zou, S., Gou, X., & Wen, K. (2023) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2023.5296 · Cited by 10

DNA repair pathways in ovarian cancer: Implications for therapy and resistance

Miras, I., Gutiérrez, I. V., Estévez-García, P., & Muñoz-Galván, S. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118719 · Cited by 10

Small RNAs: Emerging key players in DNA double-strand break repair

Ba, Z., & Qi, Y. (2013) · Science China Life Sciences · doi:10.1007/s11427-013-4552-7 · Cited by 9

Biochemical Activities and Genetic Functions of the Drosophila melanogaster Fancm Helicase in DNA Repair

Romero, N.-E., Matson, S. W., & Sekelsky, J. J. (2016) · Genetics · doi:10.1534/genetics.116.192534 · Cited by 9

In Utero Gene Therapy and Genome Editing

Hartman, H. A., Rossidis, A. C., & Peranteau, W. H. (2018) · Current Stem Cell Reports · doi:10.1007/s40778-018-0117-9 · Cited by 9

Role of homologous recombination genesRAD51,RAD52, andRAD59in the repair of lesions caused by γ-radiation to cycling and G2/M-arrested cells ofCandida albicans

Bellido, A., Hermosa, B., Ciudad, T., & Larriba, G. (2018) · Cellular Microbiology · doi:10.1111/cmi.12950 · Cited by 10

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging

O’Sullivan, J., Mersaoui, S. Y., Poirier, G. G., & Masson, J. (2021) · Journal of Visualized Experiments · doi:10.3791/62553 · Cited by 10

Identification of Nanog as a novel inhibitor of Rad51

Xin, Y., Wang, J., Wu, Y., Li, Q., Dong, M., Liu, C., He, Q., Wang, R., Wang, D., Jiang, S., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04644-9 · Cited by 9

Corruption of DNA End-Joining in Mammalian Chromosomes by Progerin Expression as Revealed by a Model Cell Culture System

Joudeh, L. A., DiCintio, A. J., Ries, M. R., Gasperson, A. S., Griffin, K. E., Robbins, V. P., Bonner, M. G., Nolan, S., Black, E. P., & Waldman, A. S. (2022) · DNA repair · doi:10.1016/j.dnarep.2023.103491 · Cited by 13

Stress Activated Protein Kinase Pathway Modulates Homologous Recombination in Fission Yeast

Bellini, A., Girard, P.-M., Lambert, S., Tessier, L., Sage, É., & Francesconi, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047987 · Cited by 9

Homologous Recombination in Mammals

Barascu, A., Grabarz, A., & López, B. S. (2012) · Topics in current genetics · doi:10.1007/978-94-007-4531-5_4 · Cited by 1

Homologous Recombination in Eukaryotes

Amunugama, R., & Fishel, R. A. (2012) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-387665-2.00007-9 · Cited by 39

Mechanism and significance of chromosome damage repair by homologous recombination

Kawale, A. S., & Sung, P. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190093 · Cited by 33

Homologous recombination in mammalian cells: From molecular mechanisms to pathology

Ragu, S., Matos-Rodrigues, G. E., THOMAS, M. L., & López, B. S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85679-9.00020-9 · Cited by 2

SURVEY AND SUMMARY Homologous recombination and its regulation

Krejčí, L., Altmannová, V., Špı́rek, M., & Zhao, X. (2012)