Regulation of Homologous Recombination in Eukaryotes

Genome maintenance mechanisms for preventing cancer

Hoeijmakers, J. H. J. (2001) · Nature · doi:10.1038/35077232 · Cited by 3,939

Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae

Pâques, F., & Haber, J. E. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.2.349-404.1999 · Cited by 2,120

Rates of spontaneous mutation

Drake, J. W., Charlesworth, B., Charlesworth, D., & Crow, J. F. (1998) · Genetics · doi:10.1093/genetics/148.4.1667 · Cited by 1,932

Mechanism of Eukaryotic Homologous Recombination

Filippo, J. S., Sung, P., & Klein, H. L. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061306.125255 · Cited by 1,766

Human CtIP promotes DNA end resection

Sartori, A. A., Lukas, C., Coates, J., Mistrik, M., Fu, S., Bartek, J., Baer, R., Lukas, J., & Jackson, S. P. (2007) · Nature · doi:10.1038/nature06337 · Cited by 1,362

Mammalian cyclin-dependent kinases

Malumbres, M., & Barbacid, M. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.09.005 · Cited by 1,333

Regulation of DNA double-strand break repair pathway choice

Shrivastav, M., De Haro, L. P., & Nickoloff, J. A. (2008) · Cell Research · doi:10.1038/cr.2007.111 · Cited by 1,329

Regulation of DNA repair throughout the cell cycle

Branzei, D., & Foiani, M. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2351 · Cited by 1,228

Homologous recombination in DNA repair and DNA damage tolerance

Li, X., & Heyer, W. (2008) · Cell Research · doi:10.1038/cr.2008.1 · Cited by 1,203

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

Zhu, Z., Chung, W.-H., Shim, E. Y., Lee, S. E., & Ira, G. (2008) · Cell · doi:10.1016/j.cell.2008.08.037 · Cited by 1,108

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

Wu, L., & Hickson, I. D. (2003) · Nature · doi:10.1038/nature02253 · Cited by 1,087

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

Sharan, S. K., Morimatsu, M., Albrecht, U., Lim, D., Regel, E., Dinh, C. Q., Sands, A., Gregor Eichele, C., Hasty, P., & Bradley, A. (1997) · Nature · doi:10.1038/386804a0 · Cited by 1,087

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

Mimitou, E. P., & Symington, L. S. (2008) · Nature · doi:10.1038/nature07312 · Cited by 1,060

EUKARYOTIC TRANSLESION SYNTHESIS DNA POLYMERASES: Specificity of Structure and Function

Prakash, S., Johnson, R. E., & Prakash, L. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133250 · Cited by 1,020

Cohesin: Its Roles and Mechanisms

Nasmyth, K., & Haering, C. H. (2009) · Annual Review of Genetics · doi:10.1146/annurev-genet-102108-134233 · Cited by 1,015

Molecular views of recombination proteins and their control

West, S. C. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1127 · Cited by 977

Choreography of the DNA Damage Response

Lisby, M., Barlow, J. H., Burgess, R. C., & Rothstein, R. (2004) · Cell · doi:10.1016/j.cell.2004.08.015 · Cited by 891

Comparative Gene Expression Profiles Following UV Exposure in Wild-Type and SOS-Deficient Escherichia coli

Courcelle, J., Khodursky, A., Peter, B., Brown, P. O., & Hanawalt, P. C. (2001) · Genetics · doi:10.1093/genetics/158.1.41 · Cited by 853

Recombination Proteins in Yeast

Krogh, B. O., & Symington, L. S. (2004) · Annual Review of Genetics · doi:10.1146/annurev.genet.38.072902.091500 · Cited by 814

Toward Maintaining the Genome: DNA Damage and Replication Checkpoints

Nyberg, K. A., Michelson, R. J., Putnam, C. W., & Weinert, T. A. (2002) · Annual Review of Genetics · doi:10.1146/annurev.genet.36.060402.113540 · Cited by 793

Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage

Lee, S. E., Moore, J. K., Holmes, A. M., Umezu, K., Kolodner, R. D., & Haber, J. E. (1998) · Cell · doi:10.1016/s0092-8674(00)81482-8 · Cited by 784

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

Ira, G., Pellicioli, A., Balijja, A., Wang, X., Fiorani, S., Carotenuto, W., Liberi, G., Bressan, D., Wan, L., Hollingsworth, N. M., et al. (2004) · Nature · doi:10.1038/nature02964 · Cited by 722

Role of BRCA2 in Control of the RAD51 Recombination and DNA Repair Protein

Davies, A. A., Masson, J., McIlwraith, M. J., Stasiak, A. Z., Stasiak, A., Venkitaraman, A. R., & West, S. C. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00175-7 · Cited by 720

Biological networks: the tinkerer as an engineer

Alon, U. (2003) · Science · doi:10.1126/science.1089072 · Cited by 706

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Sørensen, C. S., Hansen, L. T., Dziegielewski, J., Syljuåsen, R. G., Lundin, C., Bartek, J., & Helleday, T. (2005) · Nature Cell Biology · doi:10.1038/ncb1212 · Cited by 666

Reading protein modifications with interaction domains

Seet, B. T., Đikić, I., Zhou, M., & Pawson, T. J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1960 · Cited by 665

The Single-End Invasion

Hunter, N. M., & Kleckner, N. E. (2001) · Cell · doi:10.1016/s0092-8674(01)00430-5 · Cited by 663

SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase

Pfander, B., Moldovan, G., Sacher, M., Hoege, C., & Jentsch, S. (2005) · Nature · doi:10.1038/nature03665 · Cited by 626

DNA helicase Srs2 disrupts the Rad51 presynaptic filament

Krejčí, L., Komen, S. V., Li, Y., Villemain, J. L., Reddy, M. S., Klein, H. L., Ellenberger, T. E., & Sung, P. (2003) · Nature · doi:10.1038/nature01577 · Cited by 624

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments

Veaute, X., Jeusset, J., Soustelle, C., Kowalczykowski, S. C., Cam, É. L., & Fabre, F. (2003) · Nature · doi:10.1038/nature01585 · Cited by 612

DNA MISMATCH REPAIR AND GENETIC INSTABILITY

Harfe, B. D., & Jinks-Robertson, S. (2000) · Annual Review of Genetics · doi:10.1146/annurev.genet.34.1.359 · Cited by 605

How the Fanconi Anemia Pathway Guards the Genome

Moldovan, G., & D’Andrea, A. D. (2009) · Annual Review of Genetics · doi:10.1146/annurev-genet-102108-134222 · Cited by 601

DNA helicases Sgs1 and BLM promote DNA double-strand break resectionPreprint

Gravel, S., Chapman, J. R., Magill, C. P., & Jackson, S. P. (2008) · Genes & Development · doi:10.1101/gad.503108 · Cited by 595

A dynamic model for replication protein A (RPA) function in DNA processing pathways

Fanning, E. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl550 · Cited by 589

Srs2 and Sgs1–Top3 Suppress Crossovers during Double-Strand Break Repair in Yeast

Ira, G., Malkova, A., Liberi, G., Foiani, M., & Haber, J. E. (2003) · Cell · doi:10.1016/s0092-8674(03)00886-9 · Cited by 571

Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions

Lopes, M., Foiani, M., & Sogo, J. M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2005.11.015 · Cited by 563

CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle

Yun, M. H., & Hiom, K. (2009) · Nature · doi:10.1038/nature07955 · Cited by 556

Principles of ubiquitin and SUMO modifications in DNA repair

Bergink, S., & Jentsch, S. (2009) · Nature · doi:10.1038/nature07963 · Cited by 554

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair

Huertas, P., & Jackson, S. P. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808906200 · Cited by 545

Mus81-Eme1 Are Essential Components of a Holliday Junction Resolvase

Boddy, M. N., Gaillard, P.-H. L., McDonald, W. H., Shanahan, P., Yates, J. R., & Russell, P. R. (2001) · Cell · doi:10.1016/s0092-8674(01)00536-0 · Cited by 545

Crosstalk between histone modifications during the DNA damage response

van Attikum, H., & Gasser, S. M. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.03.001 · Cited by 542

Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase.

Sung, P. (1997) · Genes & Development · doi:10.1101/gad.11.9.1111 · Cited by 540

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

Galanty, Y., Belotserkovskaya, R., Coates, J., Polo, S. E., Miller, K. M., & Jackson, S. P. (2009) · Nature · doi:10.1038/nature08657 · Cited by 536

Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae.

Kadyk, L. C., & Hartwell, L. H. (1992) · Genetics · doi:10.1093/genetics/132.2.387 · Cited by 525

Crosstalk between SUMO and Ubiquitin on PCNA Is Mediated by Recruitment of the Helicase Srs2p

Papouli, E., Chen, S., Davies, A. A., Huttner, D., Krejčí, L., Sung, P., & Ulrich, H. D. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.06.001 · Cited by 522

Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends

de Jager, M., van Noort, J., van Gent, D. C., Dekker, C., Kanaar, R., & Wyman, C. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00381-1 · Cited by 512

CDK targets Sae2 to control DNA-end resection and homologous recombination

Huertas, P., Cortés‐Ledesma, F., Sartori, A. A., Aguilera, A., & Jackson, S. P. (2008) · Nature · doi:10.1038/nature07215 · Cited by 509

Genetic Steps of Mammalian Homologous Repair with Distinct Mutagenic Consequences

Stark, J. M., Pierce, A. J., Oh, J., Pastink, A., & Jasin, M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.21.9305-9316.2004 · Cited by 501

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

Esashi, F., Christ, N., Gannon, J., Liu, Y., Hunt, T., Jasin, M., & West, S. C. (2005) · Nature · doi:10.1038/nature03404 · Cited by 473

Maintenance of Genome Stability in Saccharomyces cerevisiae

Kolodner, R. D., Putnam, C. D., & Myung, K. (2002) · Science · doi:10.1126/science.1075277 · Cited by 470

Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95

Trujillo, K. M., Yuan, S. F., Lee, E. Y.-H. P., & Sung, P. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.34.21447 · Cited by 433

DNA Damage-Induced Cell Cycle Checkpoint Control Requires CtIP, a Phosphorylation-Dependent Binding Partner of BRCA1 C-Terminal Domains

Yu, X., & Chen, J. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.21.9478-9486.2004 · Cited by 410

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

Hanada, K., Budzowska, M., Davies, S. L., van Drunen, E., Onizawa, H., Beverloo, H. B., Maas, A., Essers, J., Hickson, I. D., & Kanaar, R. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1313 · Cited by 392

Genetic Requirements for the Single-Strand Annealing Pathway of Double-Strand Break Repair in Saccharomyces cerevisiae

Ivanov, E. L., Sugawara, N., Fishman‐Lobell, J., & Haber, J. E. (1996) · Genetics · doi:10.1093/genetics/142.3.693 · Cited by 390

The CDK regulates repair of double‐strand breaks by homologous recombination during the cell cycle

Aylon, Y., Liefshitz, B., & Kupiec, M. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600469 · Cited by 387

The Smc5–Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus

Torres‐Rosell, J., Šunjevarić, I., Piccoli, G. D., Sacher, M., Eckert‐Boulet, N., Reid, R. J. D., Jentsch, S., Rothstein, R. J., Aragón, L., & Lisby, M. (2007) · Nature Cell Biology · doi:10.1038/ncb1619 · Cited by 379

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

Morris, J. R., Boutell, C., Keppler, M., Densham, R., Weekes, D., Alamshah, A., Butler, L., Galanty, Y., Pangon, L., Kiuchi, T., et al. (2009) · Nature · doi:10.1038/nature08593 · Cited by 375

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

Barber, L. J., Youds, J. L., Ward, J. D., McIlwraith, M. J., O'Neil, N. J., Petalcorin, M. I. R., Martin, J. S., Collis, S. J., Cantor, S. B., Auclair, M., et al. (2008) · Cell · doi:10.1016/j.cell.2008.08.016 · Cited by 369

Homologous recombination is responsible for cell death in the absence of the Sgs1 and Srs2 helicases

Gangloff, S., Soustelle, C., & Fabre, F. (2000) · Nature Genetics · doi:10.1038/76055 · Cited by 363

Semidominant Suppressors of Srs2 Helicase Mutations of Saccharomyces cerevisiae Map in the RAD51 Gene, Whose Sequence Predicts a Protein with Similarities to Procaryotic RecA Proteins

Aboussekhra, A., Chanet, R., Adjiri, A., & Fabre, F. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.7.3224-3234.1992 · Cited by 358

Template switching during break-induced replication

Smith, C. E., Llorente, B., & Symington, L. S. (2007) · Nature · doi:10.1038/nature05723 · Cited by 355

In Vivo Roles of Rad52, Rad54, and Rad55 Proteins in Rad51-Mediated Recombination

Sugawara, N., Wang, X., & Haber, J. E. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00269-7 · Cited by 354

Mutational robustness can facilitate adaptation

Draghi, J. A., Parsons, T. L., Wagner, G. P., & Plotkin, J. B. (2010) · Nature · doi:10.1038/nature08694 · Cited by 336

The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA–ssDNA junction

Yang, H., Li, Q., Fan, J., Holloman, W. K., & Pavletich, N. P. (2005) · Nature · doi:10.1038/nature03234 · Cited by 335

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

Nimonkar, A. V., Özsoy, A. Z., Genschel, J., Modrich, P. L., & Kowalczykowski, S. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809380105 · Cited by 322

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filamentsPreprint

Hu, Y., Raynard, S. J., Sehorn, M. G., Lu, X., Bussen, W., Zheng, L., Stark, J. M., Barnes, E. L., Chi, P., Janščák, P., et al. (2007) · Genes & Development · doi:10.1101/gad.1609107 · Cited by 322

Replication fork reactivation downstream of a blocked nascent leading strand

Heller, R. C., & Marians, K. J. (2006) · Nature · doi:10.1038/nature04329 · Cited by 318

Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication

Fabre, F., Chan, A., Heyer, W., & Gangloff, S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.252652399 · Cited by 318

SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination

Myung, K., Datta, A., Chen, C., & Kolodner, R. D. (2001) · Nature Genetics · doi:10.1038/83673 · Cited by 316

Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex.

Lengsfeld, B., Rattray, A., Bhaskara, V., Ghirlando, R., & Paull, T. (2007) · Molecules and Cells · doi:10.1016/j.molcel.2007.11.001 · Cited by 316

The controlling role of ATM in homologous recombinational repair of DNA damage

Morrison, C., Sonoda, E., Takao, N., Shinohara, A., Yamamoto, K., & Takeda, S. (2000) · The EMBO Journal · doi:10.1093/emboj/19.3.463 · Cited by 312 · cited 1×

BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIPPreprint

Yu, X., Fu, S., Lai, M., Baer, R. J., & Chen, J. (2006) · Genes & Development · doi:10.1101/gad.1431006 · Cited by 302

Novel pro- and anti-recombination activities of the Bloom’s syndrome helicasePreprint

Bugreev, D. V., Yu, X., Egelman, E. H., & Mazin, A. V. (2007) · Genes & Development · doi:10.1101/gad.1609007 · Cited by 297

The RecQ DNA Helicases in DNA Repair

Bernstein, K. A., Gangloff, S., & Rothstein, R. J. (2010) · Annual Review of Genetics · doi:10.1146/annurev-genet-102209-163602 · Cited by 297

Potential Role for the BLM Helicase in Recombinational Repair via a Conserved Interaction with RAD51

Wu, L., Davies, S. L., Levitt, N. C., & Hickson, I. D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009471200 · Cited by 296

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins.

Hays, S. L., Firmenich, A. A., & Berg, P. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.15.6925 · Cited by 296

Ubc9- and Mms21-Mediated Sumoylation Counteracts Recombinogenic Events at Damaged Replication Forks

Branzei, D., Sollier, J., Liberi, G., Zhao, X., Maeda, D., Seki, M., Enomoto, T., Ohta, K., & Foiani, M. (2006) · Cell · doi:10.1016/j.cell.2006.08.050 · Cited by 291

The structure‐specific endonuclease Mus81–Eme1 promotes conversion of interstrand DNA crosslinks into double‐strands breaks

Hanada, K., Budzowska, M., Modesti, M., Maas, A., Wyman, C., Essers, J., & Kanaar, R. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601344 · Cited by 290

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

Davies, A. A., Huttner, D., Daigaku, Y., Chen, S., & Ulrich, H. D. (2008) · Molecular Cell · doi:10.1016/j.molcel.2007.12.016 · Cited by 281

Exo1 Processes Stalled Replication Forks and Counteracts Fork Reversal in Checkpoint-Defective Cells

Cotta‐Ramusino, C., Fachinetti, D., Lucca, C., Doksani, Y., Lopes, M., Sogo, J. M., & Foiani, M. (2005) · Molecular Cell · doi:10.1016/j.molcel.2004.11.032 · Cited by 281

BLM Ortholog, Sgs1, Prevents Aberrant Crossing-over by Suppressing Formation of Multichromatid Joint Molecules

Oh, S. D., Lao, J. P., Hwang, P. Y.-H., Taylor, A. F., Smith, G. R., & Hunter, N. (2007) · Cell · doi:10.1016/j.cell.2007.05.035 · Cited by 278

The Fanconi Anemia Protein FANCM Can Promote Branch Migration of Holliday Junctions and Replication Forks

Gari, K., Décaillet, C., Stasiak, A. Z., Stasiak, A., & Constantinou, A. (2008) · Molecular Cell · doi:10.1016/j.molcel.2007.11.032 · Cited by 274

Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombinationPreprint

Prakash, R., Satory, D., Dray, E. V., Papusha, A., Scheller, J., Kramer, W., Krejčí, L., Klein, H. L., Haber, J. E., Sung, P., et al. (2009) · Genes & Development · doi:10.1101/gad.1737809 · Cited by 270

SUMOylation regulates Rad18-mediated template switch

Branzei, D., Vanoli, F., & Foiani, M. (2008) · Nature · doi:10.1038/nature07587 · Cited by 256

Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs.

Worth, L., Clark, S., Radman, M., & Modrich, P. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3238 · Cited by 256

Rad54: the Swiss Army knife of homologous recombination?

Heyer, W., Li, X., Rolfsmeier, M. L., & Zhang, X. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl481 · Cited by 254

Drosophila BLM in Double-Strand Break Repair by Synthesis-Dependent Strand Annealing

Adams, M. D., McVey, M., & Sekelsky, J. J. (2003) · Science · doi:10.1126/science.1077198 · Cited by 246

Ca 2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity

Bugreev, D. V., & Mazin, A. V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402105101 · Cited by 245

Double Holliday junctions are intermediates of DNA break repair

Bzymek, M., Thayer, N. H., Oh, S. D., Kleckner, N. E., & Hunter, N. (2010) · Nature · doi:10.1038/nature08868 · Cited by 243

Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase

Bachrati, C. Z. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl258 · Cited by 242

Nucleases and helicases take center stage in homologous recombination

Mimitou, E. P., & Symington, L. S. (2009) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2009.01.010 · Cited by 238

Remodeling of DNA replication structures by the branch point translocase FANCM

Gari, K., Décaillet, C., Delannoy, M., Wu, L., & Constantinou, A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804777105 · Cited by 234

Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast

Datta, A., Hendrix, M. M., Lipsitch, M., & Jinks-Robertson, S. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.18.9757 · Cited by 229

Parameter Sensitivity as a Criterion for Evaluating and Comparing the Performance of Biochemical Systems

Savageau, M. A. (1971) · Nature · doi:10.1038/229542a0 · Cited by 222

Mitotic Crossovers between Diverged Sequences Are Regulated by Mismatch Repair Proteins in Saccharomyces cerevisiae

Datta, A., Adjiri, A., New, L., Crouse, G. F., & Jinks-Robertson, S. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.3.1085 · Cited by 214

Telomeric Strategies: Means to an End

Jain, D., & Cooper, J. P. (2010) · Annual Review of Genetics · doi:10.1146/annurev-genet-102108-134841 · Cited by 205

Heteroduplex rejection during single-strand annealing requires Sgs1 helicase and mismatch repair proteins Msh2 and Msh6 but not Pms1

Sugawara, N., Goldfarb, T., Studamire, B., Alani, E., & Haber, J. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305749101 · Cited by 200

Radiobiological and Genetic Studies on a Polyploid Series (Haploid to Hexaploid) of Saccharomyces cerevisiae

Mortimer, R. (1958) · Radiation Research · doi:10.2307/3570795 · Cited by 196

RADH, a gene ofSaccharomyces cerevisiaeencoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene

Aboussekhra, A., Chanet, R., Zgaga, Z., Cassier‐Chauvat, C., Heude, M., & Fabre, F. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.18.7211 · Cited by 195

Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths

Lee, S. E., Pâques, F., Sylvan, J. B., & Haber, J. E. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80339-x · Cited by 195

Transient Stability of DNA Ends Allows Nonhomologous End Joining to Precede Homologous Recombination

Frank-Vaillant, M., & Marcand, S. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00705-0 · Cited by 194

Control of Rad52 recombination activity by double-strand break-induced SUMO modification

Sacher, M., Pfander, B., Hoege, C., & Jentsch, S. (2006) · Nature Cell Biology · doi:10.1038/ncb1488 · Cited by 188

RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis

Youds, J. L., Mets, D. G., McIlwraith, M. J., Martin, J. S., Ward, J. D., O’Neil, N. J., Rose, A. M., West, S. C., Meyer, B. J., & Boulton, S. J. (2010) · Science · doi:10.1126/science.1183112 · Cited by 186

RAD51 -Dependent Break-Induced Replication Differs in Kinetics and Checkpoint Responses from RAD51 -Mediated Gene Conversion

Malkova, A., Naylor, M. L., Yamaguchi, M., Ira, G., & Haber, J. E. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.3.933-944.2005 · Cited by 181

The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channeling DNA lesions into the RAD52 DNA repair pathway.

Schiestl, R. H., Prakash, S., & Prakash, L. (1990) · Genetics · doi:10.1093/genetics/124.4.817 · Cited by 179

NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the Ligase IV pathwayPreprint

Frank-Vaillant, M., & Marcand, S. (2001) · Genes & Development · doi:10.1101/gad.206801 · Cited by 166

Regulation of Meiotic Recombination via Mek1-Mediated Rad54 Phosphorylation

Niu, H., Wan, L., Busygina, V., Kwon, Y., Allen, J. J., Li, X., Kunz, R. C., Kubota, K., Wang, B., Sung, P., et al. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.09.029 · Cited by 164

Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response

Morin, I., Ngo, H., Greenall, A., Zubko, M. K., Morrice, N., & Lydall, D. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.171 · Cited by 164

DNA repair protein Rad55 is a terminal substrate of the DNA damage checkpoints

Bashkirov, V. I., King, J. S., Bashkirova, E. V., Schmuckli-Maurer, J., & Heyer, W.-D. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.12.4393-4404.2000 · Cited by 164

Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification

Eladad, S., Ye, T.-Z., Hu, P., Leversha, M. A., Beresten, S. F., Matunis, M. J., & Ellis, N. A. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi145 · Cited by 158

Cdc2–cyclin B kinase activity links Crb2 and Rqh1–topoisomerase IIIPreprint

Caspari, T., Murray, J. M., & Carr, A. M. (2002) · Genes & Development · doi:10.1101/gad.221402 · Cited by 156

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M

Bakker, S. T., van de Vrugt, H. J., Rooimans, M. A., Oostra, A. B., Steltenpool, J., Delzenne‐Goette, E., van der Wal, A., van der Valk, M., Joenje, H., Riele, H. T., et al. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp297 · Cited by 154

Human and mouse homologs of the Saccharomyces cerevisiaeRAD54 DNA repair gene: evidence for functional conservation

Kanaar, R., Troelstra, C., Swagemakers, S. M. A., Essers, J., Smit, B., Franssen, J. H., Pastink, A., Bezzubova, O. Y., Buerstedde, J.-M., Clever, B., et al. (1996) · Current Biology · doi:10.1016/s0960-9822(02)00606-1 · Cited by 152

Mus81/Mms4 Endonuclease and Sgs1 Helicase Collaborate to Ensure Proper Recombination Intermediate Metabolism during Meiosis

Jessop, L., & Lichten, M. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.05.021 · Cited by 151

The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair

Sun, W., Nandi, S., Osman, F., Ahn, J. S., Jakovleska, J., Lorenz, A., & Whitby, M. C. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.08.024 · Cited by 147

Competition between the Rad50 Complex and the Ku Heterodimer Reveals a Role for Exo1 in Processing Double-Strand Breaks but Not Telomeres

Tomita, K., Matsuura, A., Caspari, T., Carr, A. M., Akamatsu, Y., Iwasaki, H., Mizuno, K., Ohta, K., Uritani, M., Ushimaru, T., et al. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5186-5197.2003 · Cited by 147

Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impairedPreprint

Tsubouchi, H., & Roeder, G. S. (2006) · Genes & Development · doi:10.1101/gad.1422506 · Cited by 145

Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stressPreprint

Kai, M., Boddy, M. N., Russell, P. R., & Wang, T. S. ‐. (2005) · Genes & Development · doi:10.1101/gad.1304305 · Cited by 144

ATP-dependent chromatin remodeling factors and DNA damage repair

Osley, M. A., Tsukuda, T., & Nickoloff, J. A. (2007) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2006.07.011 · Cited by 144

A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repairPreprint

Jain, S., Sugawara, N., Lydeard, J. R., Vaze, M. B., Gac, N. T. L., & Haber, J. E. (2009) · Genes & Development · doi:10.1101/gad.1751209 · Cited by 140

Cell cycle-dependent protein expression of mammalian homologs of yeast DNA double-strand break repair genes Rad51 and Rad52

Chen, F., Nastasi, A. J., Shen, Z., Brenneman, M. A., Crissman, H. A., & Chen, D. J. (1997) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(97)00020-7 · Cited by 131

SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks

Ouyang, K. J., Woo, L. L., Zhu, J., Huo, D., Matunis, M. J., & Ellis, N. A. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000252 · Cited by 128

Molecular Genetics of Recombination

Heyer, W.-D. (2007) · Topics in current genetics · doi:10.1007/978-3-540-71021-9 · Cited by 128

The Srs2 Helicase Activity Is Stimulated by Rad51 Filaments on dsDNA: Implications for Crossover Incidence during Mitotic Recombination

Pauline, D., Breton, C. L., Fabre, F., Gangloff, S., Cam, É. L., & Veaute, X. (2008) · Molecular Cell · doi:10.1016/j.molcel.2007.11.033 · Cited by 127

The Functions of Budding Yeast Sae2 in the DNA Damage Response Require Mec1- and Tel1-Dependent Phosphorylation

Baroni, E., Viscardi, V., Cartagena‐Lirola, H., Lucchini, G., & Longhese, M. P. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.10.4151-4165.2004 · Cited by 125

The F-Box DNA Helicase Fbh1 Prevents Rhp51-Dependent Recombination without Mediator Proteins

Osman, F., Dixon, J. E., Barr, A. R., & Whitby, M. C. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.18.8084-8096.2005 · Cited by 121

Yeast cell-type regulation of DNA repair

Åström, S. U., Okamura, S. M., & Rine, J. (1999) · Nature · doi:10.1038/16833 · Cited by 119

Molecular Dissection of Mitotic Recombination in the Yeast Saccharomyces cerevisiae

Aylon, Y., Liefshitz, B., Bitan-Banin, G., & Kupiec, M. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.4.1403-1417.2003 · Cited by 117

Regulation of Mitotic Homeologous Recombination in Yeast: Functions of Mismatch Repair and Nucleotide Excision Repair Genes

Nicholson, A. C., Hendrix, M. M., Jinks-Robertson, S., & Crouse, G. F. (2000) · Genetics · doi:10.1093/genetics/154.1.133 · Cited by 114

FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange

Sommers, J. A., Rawtani, N., Gupta, R., Bugreev, D. V., Mazin, A. V., Cantor, S. B., & Brosh, R. M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m809019200 · Cited by 112

Chromosomal Instability in Microsatellite-Unstable and Stable Colon Cancer

Trautmann, K., Terdiman, J. P., French, A. J., Roydasgupta, R., Sein, N., Kakar, S., Fridlyand, J., Snijders, A. M., Albertson, D. G., Thibodeau, S. N., et al. (2006) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-1248 · Cited by 112

Rad54 dissociates homologous recombination intermediates by branch migration

Bugreev, D. V., Hanaoka, F., & Mazin, A. V. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1268 · Cited by 111

RECQL, a Member of the RecQ Family of DNA Helicases, Suppresses Chromosomal Instability

Sharma, S., Stumpo, D. J., Balajee, A. S., Bock, C. B., Lansdorp, P. M., Brosh, R. M., & Blackshear, P. J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01620-06 · Cited by 111

Hed1 regulates Rad51-mediated recombination via a novel mechanismPreprint

Busygina, V., Sehorn, M. G., Shi, I. Y., Tsubouchi, H., Roeder, G. S., & Sung, P. (2008) · Genes & Development · doi:10.1101/gad.1638708 · Cited by 111

Mismatch Repair Proteins Regulate Heteroduplex Formation during Mitotic Recombination in Yeast

Chen, W., & Jinks-Robertson, S. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.11.6525 · Cited by 110

The FANCM family of DNA helicases/translocases

Whitby, M. C. (2010) · DNA repair · doi:10.1016/j.dnarep.2009.12.012 · Cited by 109

Human RECQ1 Is a DNA Damage Responsive Protein Required for Genotoxic Stress Resistance and Suppression of Sister Chromatid Exchanges

Sharma, S., & Brosh, R. M. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001297 · Cited by 106

Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

Fugger, K., Mistrík, M., Danielsen, J. M. R., Dinant, C., Falck, J., Bártek, J., Lukas, J., & Mailand, N. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200812138 · Cited by 106

DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair

Youds, J. L., Barber, L. J., Ward, J. D., Collis, S. J., O’Neil, N. J., Boulton, S. J., & Rose, A. M. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01641-07 · Cited by 100

Yeast MPH1 Gene Functions in an Error-Free DNA Damage Bypass Pathway That Requires Genes From Homologous Recombination, but Not From Postreplicative Repair

Schürer, K. A., Rudolph, C. J., Ulrich, H. D., & Kramer, W. (2004) · Genetics · doi:10.1534/genetics.166.4.1673 · Cited by 99

Overlapping Mechanisms Promote Postsynaptic RAD-51 Filament Disassembly during Meiotic Double-Strand Break Repair

Ward, J. D., Muzzini, D. M., Petalcorin, M. I. R., Martínez-Pérez, E., Martin, J. S., Plevani, P., Cassata, G., Marini, F., & Boulton, S. J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2009.12.026 · Cited by 97

Cellular Redistribution of Rad51 in Response to DNA Damage

Gildemeister, O. S., Sage, J. M., & Knight, K. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.024646 · Cited by 95

Phosphorylation of Rad55 on Serines 2, 8, and 14 Is Required for Efficient Homologous Recombination in the Recovery of Stalled Replication Forks

Herzberg, K., Bashkirov, V. I., Rolfsmeier, M., Haghnazari, E., McDonald, W. H., Anderson, S., Bashkirova, E. V., Yates, J. R., & Heyer, W.-D. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01317-06 · Cited by 95

Induced intragenic recombination in yeast can occur during the G1 mitotic phase

Fabre, F. (1978) · Nature · doi:10.1038/272795a0 · Cited by 92

Rad51 Protein Controls Rad52-mediated DNA Annealing

Wu, Y., Kantake, N., Sugiyama, T., & Kowalczykowski, S. C. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801097200 · Cited by 90

Examination of the Roles of Sgs1 and Srs2 Helicases in the Enforcement of Recombination Fidelity in Saccharomyces cerevisiae

Spell, R. M., & Jinks-Robertson, S. (2004) · Genetics · doi:10.1534/genetics.104.032771 · Cited by 89

Functional Interaction between the Bloom's Syndrome Helicase and the RAD51 Paralog, RAD51L3 (RAD51D)

Braybrooke, J. P., Li, J., Wu, L., Caple, F., Benson, F. E., & Hickson, I. D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m308838200 · Cited by 88

Cleavage of Stalled Forks by Fission Yeast Mus81/Eme1 in Absence of DNA Replication Checkpoint

Froget, B., Blaisonneau, J., Lambert, S., & Baldacci, G. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-07-0728 · Cited by 88

Semidominant Mutations in the Yeast Rad51 Protein and Their Relationships with the Srs2 Helicase

Chanet, R., Heude, M., Adjiri, A., Maloisel, L., & Fabre, F. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.9.4782 · Cited by 85

Budding Yeast Sae2 is an In Vivo Target of the Mec1 and Tel1 Checkpoint Kinases During Meiosis

Cartagena‐Lirola, H., Guerini, I., Viscardi, V., Lucchini, G., & Longhese, M. P. (2006) · Cell Cycle · doi:10.4161/cc.5.14.2916 · Cited by 85

ATR-dependent pathways control hEXO1 stability in response to stalled forks

El‐Shemerly, M., Heß, D., Pyakurel, A., Moselhy, S. S., & Ferrari, S. M. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm1052 · Cited by 82

Regulation of yeast sirtuins by NAD+ metabolism and calorie restriction

Lu, S.-P., & Lin, S.-J. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2009.09.030 · Cited by 77

Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatinPreprint

Holzen, T. M., Shah, P. P., Olivares, H. A., & Bishop, D. K. (2006) · Genes & Development · doi:10.1101/gad.1447106 · Cited by 77

The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair

Rosado, I. V., Niedźwiedź, W., Alpi, A. F., & Patel, K. J. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp365 · Cited by 77

RECQ1 Possesses DNA Branch Migration Activity

Bugreev, D. V., Brosh, R. M., & Mazin, A. V. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801582200 · Cited by 74

Regulated degradation of FANCM in the Fanconi anemia pathway during mitosisPreprint

Kee, Y., Kim, J. M., & D’Andrea, A. D. (2009) · Genes & Development · doi:10.1101/gad.1761309 · Cited by 74

Behind the wheel and under the hood: Functions of cyclin-dependent kinases in response to DNA damage

Wohlbold, L., & Fisher, R. P. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.04.009 · Cited by 67

Quality control of DNA break metabolism: in the ‘end’, it's a good thing

Kanaar, R., Wyman, C., & Rothstein, R. J. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.11 · Cited by 66

Failure to induce a DNA repair gene, RAD54, in Saccharomyces cerevisiae does not affect DNA repair or recombination phenotypes.

Cole, G. M., & Mortimer, R. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.8.3314 · Cited by 62

The Human F-Box DNA Helicase FBH1 Faces Saccharomyces cerevisiae Srs2 and Postreplication Repair Pathway Roles

Chiolo, I., Saponaro, M., Baryshnikova, A., Kim, J., Seo, Y., & Liberi, G. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00963-07 · Cited by 60

Esc2 and Sgs1 Act in Functionally Distinct Branches of the Homologous Recombination Repair Pathway in Saccharomyces cerevisiae

Mankouri, H. W., Ngo, H.-P., & Hickson, I. D. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-08-0877 · Cited by 59

Some disassembly required: role of DNA translocases in the disruption of recombination intermediates and dead-end complexesPreprint

Symington, L. S., & Heyer, W. (2006) · Genes & Development · doi:10.1101/gad.1477106 · Cited by 58

Influence of DNA Sequence Identity on Efficiency of Targeted Gene Replacement

Negritto, M. T., Wu, X., Kuo, T., Chu, S., & Bailis, A. M. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.1.278 · Cited by 57

Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination

Banerjee, S., Smith, S. N., Oum, J., Liaw, H., Hwang, J., Sikdar, N., Motegi, A., Lee, S. E., & Myung, K. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200711146 · Cited by 47

Multiple start codons and phosphorylation result in discrete Rad52 protein species

de Mayolo, A. A., Lisby, M., Erdeniz, N., Thybo, T., Mortensen, U. H., & Rothstein, R. J. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl280 · Cited by 39

Biochemistry of Eukaryotic Homologous Recombination

Heyer, W. (2006) · Springer eBooks · doi:10.1007/978-3-540-71021-9_4 · Cited by 39

Different Mating-Type-Regulated Genes Affect the DNA Repair Defects of SaccharomycesRAD51,RAD52andRAD55Mutants

Valencia‐Burton, M., Oki, M., Johnson, J., Seier, T., Kamakaka, R. T., & Haber, J. E. (2006) · Genetics · doi:10.1534/genetics.106.058685 · Cited by 38

Sequence Divergence Impedes Crossover More Than Noncrossover Events During Mitotic Gap Repair in Yeast

Welz-Voegele, C., & Jinks-Robertson, S. (2008) · Genetics · doi:10.1534/genetics.108.090233 · Cited by 38

Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates

Ehmsen, K. T., & Heyer, W. (2008) · Genome dynamics and stability · doi:10.1007/7050_2008_039 · Cited by 35

Nej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism

Carter, S. D., Vigašová, D., Chen, J., Chovanec, M., & Åström, S. U. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903869106 · Cited by 27

Meiotic recombination

Hunter, N. M. (2006) · Springer eBooks · doi:10.1007/4735_2006_0215 · Cited by 27

Sae2p phosphorylation is crucial for cooperation with Mre11p for resection of DNA double-strand break ends during meiotic recombination in Saccharomyces cerevisiae

Terasawa, M., Ogawa, T., Tsukamoto, Y., & Ogawa, H. (2008) · Genes & Genetic Systems · doi:10.1266/ggs.83.209 · Cited by 26

Genetic evidence for a role of Saccharomyces cerevisiae Mph1 in recombinational DNA repair under replicative stress

Panico, E. R., Ede, C., Schildmann, M., Schürer, K. A., & Kramer, W. (2009) · Yeast · doi:10.1002/yea.1727 · Cited by 26

Failure To Induce a DNA Repair Gene, RAD54 , in Saccharomyces cerevisiae Does Not Affect DNA Repair or Recombination Phenotypes

Cole, G. M., & Mortimer, R. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.8.3314-3322.1989 · Cited by 26

A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae

Janke, R., Herzberg, K., Rolfsmeier, M. L., Mar, J. S., Bashkirov, V. I., Haghnazari, E., Cantin, G. T., Yates, J. R., & Heyer, W. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkp1222 · Cited by 25

Mph1 requires mismatch repair-independent and -dependent functions of MutSα to regulate crossover formation during homologous recombination repair

Tay, Y. D., Sidebotham, J. M., & Wu, L. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkp1199 · Cited by 24

The Anaphase-Promoting Complex/Cyclosome Controls Repair and Recombination by Ubiquitylating Rhp54 in Fission Yeast

Trickey, M., Grimaldi, M., & Yamano, H. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.02116-07 · Cited by 23

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Anzalone, A. V., Koblan, L. W., & Liu, D. R. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-0561-9 · Cited by 2,237

Repair Pathway Choices and Consequences at the Double-Strand Break

Ceccaldi, R., Rondinelli, B., & D’Andrea, A. D. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.07.009 · Cited by 1,499

DNA double-strand break repair-pathway choice in somatic mammalian cells

Scully, R., Panday, A., Elango, R., & Willis, N. A. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0152-0 · Cited by 1,542

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

Lin, S., Staahl, B. T., Alla, R. K., & Doudna, J. A. (2014) · eLife · doi:10.7554/elife.04766 · Cited by 1,189

Double-strand break repair: 53BP1 comes into focus

Panier, S., & Boulton, S. J. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3719 · Cited by 1,168

Homologous Recombination in Mammals

Barascu, A., Grabarz, A., & López, B. S. (2012) · Topics in current genetics · doi:10.1007/978-94-007-4531-5_4 · Cited by 1

Homologous Recombination in Eukaryotes

Amunugama, R., & Fishel, R. A. (2012) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-387665-2.00007-9 · Cited by 39

Mechanism and significance of chromosome damage repair by homologous recombination

Kawale, A. S., & Sung, P. (2020) · Essays in Biochemistry · doi:10.1042/ebc20190093 · Cited by 33

Homologous recombination in mammalian cells: From molecular mechanisms to pathology

Ragu, S., Matos-Rodrigues, G. E., THOMAS, M. L., & López, B. S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85679-9.00020-9 · Cited by 2

SURVEY AND SUMMARY Homologous recombination and its regulation

Krejčí, L., Altmannová, V., Špı́rek, M., & Zhao, X. (2012)