The DOI matches its Crossref record; 90 of the 91 references it cites were found in a registry or an index.
Addiction Circuitry in the Human Brain
Open accessAbstract
A major challenge in understanding substance-use disorders lies in uncovering why some individuals become addicted when exposed to drugs, whereas others do not. Although genetic, developmental, and environmental factors are recognized as major contributors to a person's risk of becoming addicted, the neurobiological processes that underlie this vulnerability are still poorly understood. Imaging studies suggest that individual variations in key dopamine-modulated brain circuits, including circuits involved in reward, memory, executive function, and motivation, contribute to some of the differences in addiction vulnerability. A better understanding of the main circuits affected by chronic drug use and the influence of social stressors, developmental trajectories, and genetic background on these circuits is bound to lead to a better understanding of addiction and to more effective strategies for the prevention and treatment of substance-use disorders.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Reductions in executive functions have considered both as vulnerability factors and consequences of addictive behaviors including substance-use disorders (Volkow et al., 2012).”
In the citing paper
“The primary subcortical brain target is the nucleus accumbens (NAc) which is considered the center of the reward circuitry and heavily implicated in substance use and craving [18–22].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Brain's Default Network: Anatomy, Function, and Relevance to Disease
Buckner, R. L., Andrews‐Hanna, J. R., & Schacter, D. L. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.011 · Cited by 9,761
Di Chiara, G., & Imperato, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5274 · Cited by 4,733
Bardo, M. T., & Hammer, R. P. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90226-e · Cited by 3,229
Wandering minds: the default network and stimulus-independent thought
Mason, M. F., Norton, M. I., Van Horn, J. D., Wegner, D. M., Grafton, S. T., & Macrae, C. N. (2007) · Science · doi:10.1126/science.1131295 · Cited by 2,792
Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667
Self-citationThe debate over dopamine’s role in reward: the case for incentive salience
Berridge, K. C. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0578-x · Cited by 2,347
A default mode of brain function: a brief history of an evolving idea
Raichle, M. E., & Snyder, A. Z. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.02.041 · Cited by 2,173
Limbic Activation During Cue-Induced Cocaine Craving
Childress, A. R., Mozley, P. D., McElgin, W., Fitzgerald, J., Reivich, M., & O’Brien, C. P. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.1.11 · Cited by 1,513
The primate basal ganglia: Parallel and integrative networks
Haber, S. N. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.10.003 · Cited by 1,479
Synaptic plasticity and addiction
Kauer, J. A., & Malenka, R. C. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2234 · Cited by 1,397
Research works printed but not linked: 3
- 10.1176/appi.ajp.164.4.622 · DOI · Paper page
- Wang GJ, 2010, J. Nucl. Med., 51, 269
- Hommer DW, 1999, Alcohol Res. Health, 23, 187
Cited by
Sorted by citations
Items 301–400 of 592
Default mode network mechanisms of repeated transcranial magnetic stimulation in heroin addiction
Jin, L. H., Yuan, M., Zhang, W., Wang, L., Chen, J., Wang, F., Zhu, J., Liu, T., Wei, Y., Li, Y., et al. (2022) · Brain Imaging and Behavior · doi:10.1007/s11682-022-00741-7 · Cited by 11
van Timmeren, T., Jansen, J. M., Caan, M. W. A., Goudriaan, A. E., & van Holst, R. J. (2016) · Addiction Biology · doi:10.1111/adb.12447 · Cited by 11
Extrinsic functional connectivity of the default mode network in crack-cocaine users
Martins, D. L. N., Valiatti, T. D. D. S., D'Ávila, J., Ferreira, L. F., Batista, E. K., Bazán, P. R., de Souza, R. S. M., & Nakamura-Palacios, E. M. (2018) · Radiologia Brasileira · doi:10.1590/0100-3984.2016.0115 · Cited by 11
GluA1 in Central Amygdala Promotes Opioid Use and Reverses Inhibitory Effect of Pain
Hou, Y.-Y., Cai, Y.-Q., & Pan, Z. Z. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.11.032 · Cited by 11
Kraiwattanapirom, N., Komlao, P., Harnpramukkul, A., Promyo, K., Ngampramuan, S., & Chetsawang, B. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112610 · Cited by 11
Dormal, V., Lannoy, S., Bollen, Z., D’Hondt, F., & Maurage, P. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05475-2 · Cited by 12
Li, X., Caulfield, K. A., Hartwell, K. J., Henderson, S., Brady, K. T., & George, M. S. (2023) · Brain Imaging and Behavior · doi:10.1007/s11682-023-00820-3 · Cited by 10
Oesterle, T., Bormann, N. L., Al‐Soleiti, M., Kung, S., Singh, B., McGinnis, M. T., da Costa, S. C., Rummans, T. A., Chauhan, M., Cabrera, J. M. R., et al. (2025) · Brain Sciences · doi:10.3390/brainsci15070723 · Cited by 10
García, S. D. O., Babarro, J. M., & Toldos-Romero, M. D. L. P. (2017) · Universal Journal of Psychology · doi:10.13189/ujp.2017.050204 · Cited by 10
Kuriki, S., Higuchi, S., Nakayama, H., Mihara, S., Okazaki, Y., Ono, Y., & Kobayashi, H. (2020) · PLoS ONE · doi:10.1371/journal.pone.0233780 · Cited by 12
Dopaminergic dysfunction: Role for genetic & epigenetic testing in the new psychiatry
Blum, K., Ashford, J. W., Kateb, B., Sipple, D., Braverman, E. R., Dennen, C. A., Baron, D. A., Badgaiyan, R. D., Elman, I., Cadet, J. L., et al. (2023) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2023.120809 · Cited by 15
The Ethics of Neuroenhancement
Wagner, N., Robinson, J., & Wiebking, C. (2015) · International Journal of Technoethics · doi:10.4018/ijt.2015010101 · Cited by 10
de la Villarmois, E. A., Gabach, L. A., Bianconi, S., Poretti, M. B., Occhieppo, V. B., Schiöth, H. B., Carlini, V. P., & Pérez, M. F. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-01725-3 · Cited by 10
Electrophysiology for addiction medicine
Stewart, J. L., & May, A. C. (2015) · Progress in brain research · doi:10.1016/bs.pbr.2015.07.013 · Cited by 10
Rosell‐Negre, P., Bustamante, J. C., Fuentes‐Claramonte, P., Costumero, V., Llácer, J. J. L., & Barrós‐Loscertales, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167400 · Cited by 10
Nicotine drug discrimination and nicotinic acetylcholine receptors in differentially reared rats
Bockman, C. S., Zeng, W., Hall, J., Mittelstet, B., Schwarzkopf, L., & Stairs, D. J. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4850-7 · Cited by 10
Levy, Y. Z., Levy, D. J., Barto, A. G., & Meyer, J. S. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00167 · Cited by 10
Brain stimulation therapeutics
Li, X., George, M. S., & Zangen, A. (2023) · Addiction Neuroscience · doi:10.1016/j.addicn.2023.100080 · Cited by 9
Brancato, A., Cavallaro, A., Lavanco, G., Plescia, F., & Cannizzaro, C. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881117725683 · Cited by 9
Sariah, A., Pu, W., Xue, Z., Liu, Z., & Huang, X. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00654 · Cited by 9
What Is It Like to Be an Addict?
Flanagan, O. (2025) · doi:10.1093/oso/9780199388929.001.0001 · Cited by 9
Assessing addiction vulnerability with different rat strains and place preference procedures
Salas, E., Bocos, C., Castillo, C. D., Pérez‐García, C., Morales, L., & Alguacil, L. F. (2013) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328364160a · Cited by 8
Goldstein, R. Z., Barrot, M., Everitt, B. J., & Foxe, J. J. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14544 · Cited by 8
Wang, L., Hu, F., Li, W., Li, Q., Li, Y., Zhu, J., Wei, X., Yang, J., Guo, J., Qin, Y., et al. (2021) · Psychological Medicine · doi:10.1017/s0033291721003937 · Cited by 8
Eskandari, K., Fattahi, M., Yazdanian, H., & Haghparast, A. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03818-3 · Cited by 7
Scientific and conceptual flaws of coercive treatment models in addiction
Uusitalo, S., & van der Eijk, Y. (2015) · Journal of Medical Ethics · doi:10.1136/medethics-2015-102910 · Cited by 9
Liu, T., Li, J., Huang, S., Zhao, Z., Yang, G., Pan, M., Li, C., Chen, F., & Pan, S. (2015) · PubMed Central · Cited by 8
Murray, D. E., Durazzo, T. C., Schmidt, T. P., Murray, T. A., Abé, C., Guydish, J. R., & Meyerhoff, D. J. (2017) · Addiction Biology · doi:10.1111/adb.12523 · Cited by 8
Antons, S., & Brand, M. (2019) · Suchttherapie · doi:10.1055/a-1018-4792 · Cited by 10
Robinson, K. J., Everett, N. A., Baracz, S. J., & Cornish, J. L. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06175-9 · Cited by 8
The Executive Functioning Paradox in Substance Use Disorders
Jakubiec, L., Chirokoff, V., Abdallah, M., Sanz‐Arigita, E., Dupuy, M., Swendsen, J. D., Berthoz, S., Gierski, F., Guionnet, S., Misdrahi, D., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10112728 · Cited by 8
Franklin, J. L., Mirzaei, M., Wearne, T. A., Homewood, J., Goodchild, A. K., Haynes, P. A., & Cornish, J. L. (2016) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b01043 · Cited by 8
Martins, B. S., Cáceda, R., Cisler, J. M., Kilts, C. D., & James, G. A. (2018) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2018.08.006 · Cited by 8
Zheng, H., Zhou, W., Wang, M., Dong, H., Lu, C., Zhang, J., Ma, X., Hu, Y., & Dong, G. (2023) · Psychoradiology · doi:10.1093/psyrad/kkad015 · Cited by 7
Effect of exercise on cravings levels in individuals with drug dependency: A systematic review
Ding, F., Jia, S., Wang, P., Liu, C., & Yu-zhang, L. (2024) · Addictive Behaviors · doi:10.1016/j.addbeh.2024.108127 · Cited by 8
Wang, P., Lin, H., Liu, T., Hsu, C., Yang, Y.-Y., Wu, H., & Yen, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.476205 · Cited by 7
Fu, L., Chen, H., Liu, T., Liu, L., Fu, Q., Huang, W., & Chen, F. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.830541 · Cited by 7
Webber, H. E., de Dios, C., Kessler, D. A., Schmitz, J. M., Lane, S. D., & Suchting, R. (2024) · Psychophysiology · doi:10.1111/psyp.14515 · Cited by 8
Brunelle, C., & Flood, M. (2015) · Journal of Substance Use · doi:10.3109/14659891.2014.884175 · Cited by 7
Wooditch, A., Sloas, L. B., & Taxman, F. S. (2016) · Journal of Drug Issues · doi:10.1177/0022042616678606 · Cited by 7
Functionally Relevant Brain Alterations in Polysubstance Users
Meyerhoff, D. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805373-7.00021-9 · Cited by 7
Association between the Intron 8 VNTR Polymorphism of the DAT1 Gene and Crack Cocaine Addiction
Stolf, A. R., Müller, D., Schuch, J. B., Akutagava‐Martins, G. C., Guimaraes, L. S. P., Szobot, C. M., Halpern, R., Kessler, F. H. P., Pechansky, F., & Roman, T. (2017) · Neuropsychobiology · doi:10.1159/000485128 · Cited by 7
Are addictions diseases or choices?
Leyton, M. (2013) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.130097 · Cited by 7
Neurobiology of chronic caffeine use and withdrawal: Mechanisms, effects and implications
Lee, Y. Z., Chua, K. N., Voon, F., Tham, C. L., Ho, Y., & Lee, M. T. (2025) · Food and Chemical Toxicology · doi:10.1016/j.fct.2025.115817 · Cited by 7
Kuo, H., Yang, Y.-H., Chen, S., Kuo, T.-H., Lin, W.-T., & Liu, F. (2023) · eNeuro · doi:10.1523/eneuro.0366-22.2023 · Cited by 7
Bounoua, N., Stumps, A. D., Church, L. D., Spielberg, J. M., & Sadeh, N. (2025) · Human Brain Mapping · doi:10.1002/hbm.70137 · Cited by 12
The Societal Hazards of Neuroenhancement Technologies
Wagner, N., Robinson, J., & Wiebking, C. (2018) · Advances in information security, privacy, and ethics book series · doi:10.4018/978-1-5225-5094-5.ch010 · Cited by 5
Bittencourt, A. M. L., da Silveira, B. L. B., Tondo, L. P., Rothmann, L. M., Franco, A. R., Ferreira, P. E., Viola, T. W., & Grassi‐Oliveira, R. (2022) · Acta Neuropsychiatrica · doi:10.1017/neu.2022.33 · Cited by 6
Liu, J.-L., Sun, J.-T., Hu, H.-L., Wang, H.-Y., Kang, Y.-X., Chen, T.-Q., Chen, Z., Shang, Y., Li, Y.-T., Hu, B., et al. (2023) · Psychiatry Investigation · doi:10.30773/pi.2021.0383 · Cited by 6
Genetic and epigenetic studies of opioid abuse disorder – the potential for future diagnostics
Abdulmalek, S., & Hardiman, G. (2023) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2023.2190022 · Cited by 9
Komlao, P., Kraiwattanapirom, N., Promyo, K., Hein, Z. M., & Chetsawang, B. (2023) · NeuroToxicology · doi:10.1016/j.neuro.2023.11.006 · Cited by 7
Farrokhi, A. M., Moshrefi, F., Eskandari, K., Azizbeigi, R., & Haghparast, A. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111025 · Cited by 7
Can Neuroscience Improve Addiction Treatment and Policies?
Nutt, D., & McLellan, A. T. (2013) · Public health reviews · doi:10.1007/bf03391704 · Cited by 6
Cognitive dysfunction and underlying neural basis in substance addiction
Zhao, H., Huang, X., & He, Q. (2016) · Chinese Science Bulletin (Chinese Version) · doi:10.1360/n972016-00533 · Cited by 5
Modeling neurocognitive and neurobiological recovery in addiction
Meyerhoff, D. J., & Durazzo, T. C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815298-0.00028-9 · Cited by 6
Dysfunction of the Prefrontal Cortex in Betel-Quid–Dependent Chewers
Kong, L., Zeng, C., Yuan, F., Liu, S., Wang, D., Jiang, C., Zhan, Z., Qian, Z., & Zhu, X. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.558367 · Cited by 6
Clinical Outcomes of Severe Forms of Early Social Stress
Berhe, O., Gerhardt, S., & Schmahl, C. G. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_261 · Cited by 7
Duncan, P. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781139025515 · Cited by 8
Ramdave, S., Dawson, A., Carter, A., & Dissanayaka, N. N. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00041-7 · Cited by 6
Malnutrition in Substance Use Disorders: A Critical Issue in Their Treatment and Recovery
Garcı́a‐Estrada, J., Luquı́n, S., Pesqueda-Cendejas, K., Ruiz-Ballesteros, A. I., Campos-López, B., Meza-Meza, M. R., Parra‐Rojas, I., González-Castañeda, R. E., Ramos-López, O., & la Cruz-Mosso, U. D. (2025) · Healthcare · doi:10.3390/healthcare13080868 · Cited by 5
Brand, M., Brandtner, A., Antons, S., Müller, A., Stark, R. M., Fineberg, N. A., Potenza, M. N., Steins‐Loeber, S., Wegmann, E., & Müller, S. M. (2026) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2026.152697 · Cited by 6
Imaging of impulse control disorders in Parkinson's disease
Prange, S., & Thobois, S. (2024) · Revue Neurologique · doi:10.1016/j.neurol.2024.09.004 · Cited by 5
Picone, J. A., Hassan, A., Kim, R. K., Lira, D. P., Silva, G. M., Truby, N. L., Johnson, H. A., Teague, C. D., Neve, R. L., Banks, M. L., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02852-7 · Cited by 5
Structural Cerebellar and Lateral Frontoparietal Networks are altered in CUD: An SBM Analysis
Lacomba‐Arnau, E., Martínez‐Molina, A., & Barrós‐Loscertales, A. (2025) · Addiction Biology · doi:10.1111/adb.70021 · Cited by 5
Antidepressant Treatment Quality of Depressed Youth: A National Evaluation of Medicaid Patients
Fontanella, C. A., Hyer, J. M., Steelesmith, D. L., Campo, J. V., Fristad, M. A., Bridge, J. A., dosReis, S., Brock, G. N., & Olfson, M. (2025) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2025.05.011 · Cited by 5
Sex, drugs and Parkinson’s disease
Ushe, M., & Perlmutter, J. S. (2013) · Brain · doi:10.1093/brain/awt022 · Cited by 5
Weng, J., Chuang, Y.-C., Zheng, L.-B., Lee, M., & Ho, M. (2022) · Brain Imaging and Behavior · doi:10.1007/s11682-022-00647-4 · Cited by 5
Vanderhasselt, M.-A., Vergauwe, R., Baeken, C., Pulopulos, M. M., & Raedt, R. D. (2025) · Clinical Psychology Review · doi:10.1016/j.cpr.2025.102611 · Cited by 6
Oortmerssen, K. V. E., Konstenius, M., & Schoevers, R. A. (2014) · Springer eBooks · doi:10.1007/978-3-642-45375-5_13 · Cited by 5
Precision therapeutic opioid dosing implications from genetic biomarkers and craving score
Chang, H.-W., Ho, W., Huang, C., & Wang, R. (2020) · Medicine · doi:10.1097/md.0000000000020429 · Cited by 5
Higher Trait Impulsivity and Altered Frontostriatal Connectivity in Betel-Quid Dependent Individuals
Qian, Z., Liu, S., Zhu, X., Kong, L., Liu, N., Wang, D., Jiang, C., Zhan, Z., & Yuan, F. (2020) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2020.578913 · Cited by 5
Nall, R. W., Chalhoub, R., & Kalivas, P. W. (2022) · Journal of the Experimental Analysis of Behavior · doi:10.1002/jeab.752 · Cited by 5
Dopamine challenge reveals neuroadaptive changes in marijuana abusers
Madras, B. K. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1412314111 · Cited by 5
“Turning the tide” in Treatment of substance use: A nursing response
Worley, J., & Delaney, K. R. (2017) · Journal of Nursing Education and Practice · doi:10.5430/jnep.v8n2p116 · Cited by 5
Drug Testing of Health Care Professionals to Improve Overall Wellness and Patient Care
Merlo, L. J. (2014) · The American Journal of Bioethics · doi:10.1080/15265161.2014.964990 · Cited by 5
The Invisible Abuser: Attachment, Victimization, and Perpetrator Perception in Repeat Abuse
Lesiak, M., & Gelsthorpe, L. R. (2025) · Violence Against Women · doi:10.1177/10778012251379423 · Cited by 4
Guerrero‐Aranda, A., Alvarado-Rodríguez, F. J., Enríquez-Zaragoza, A., Carmona-Huerta, J., & González‐Garrido, A. A. (2023) · Clinical EEG and Neuroscience · doi:10.1177/15500594231208245 · Cited by 4
Astrocyte-Neuron Interactions in Substance Use Disorders
Harder, E. V., Franklin, J. P., VanRyzin, J. W., & Reissner, K. J. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-64839-7_7 · Cited by 5
Peeters, L. D., Wills, L. J., Cuozzo, A. M., Ahmed, C. D., Massey, S. R., Chen, W., Chen, Z., Wang, C., Gass, J. T., & Brown, R. W. (2024) · Journal of Psychopharmacology · doi:10.1177/02698811241292902 · Cited by 4
Neuroimaging in clinical studies of craving: Importance of reward and control networks.
Thayer, R. E., & Hutchison, K. E. (2013) · Psychology of Addictive Behaviors · doi:10.1037/a0030275 · Cited by 4
Tunstall, B. J., Verendeev, A., & Kearns, D. N. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.08.029 · Cited by 4
Peris‐Sampedro, F., Guardia-Escote, L., Basaure, P., Cabré, M., & Colomina, M. T. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112552 · Cited by 5
Alcoholic Beverage Advertising: An Integrative Interdisciplinary Review
Hovland, R. (2015) · Journal of Current Issues & Research in Advertising · doi:10.1080/10641734.2014.912598 · Cited by 4
The Influence of Pain on Reward Processing: Current Literature and Prospects
Gandhi, W., Becker, S., & Schweinhardt, P. (2014) · Contemporary clinical neuroscience · doi:10.1007/978-1-4939-1856-0_3 · Cited by 4
Dezhakam, A., Dezhakam, H., & Haghighatfard, A. (2022) · Research Square · doi:10.21203/rs.3.rs-1663207/v1 · Cited by 4
Wang, K., Li, Y., Zhang, T., Liu, H., & Luo, J. (2025) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2025.01.001 · Cited by 4
Genome-wide association study of cocaine self-administration behavior in Heterogeneous Stock rats
Lara, M. K., Carrette, L. L. G., Sanches, T. M., Polesskaya, O., Avelar, A., Beeson, A., Beldjoud, H., Boomhower, B., Brennan, M., Chen, D., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-73694-w · Cited by 5
Cocaine seeking and consumption are oppositely regulated by mesolimbic dopamine in male rats
Burgeno, L. M., Farero, R. D., Murray, N. L., Panayi, M. C., Steger, J. S., Soden, M. E., Evans, S. B., Sandberg, S. G., Willuhn, I., Zweifel, L. S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64885-y · Cited by 9
Azahar, Q., & Mansor, S. (2026) · Brain Imaging and Behavior · doi:10.1007/s11682-026-01132-y · Cited by 3
Liu, Y., Zhang, M., Tian, Y., Zhou, S., Shen, Y., Ma, L., Mei, B., Wang, W., Han, S., & Zhang, Y. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111703 · Cited by 3
Miki, T., Kusaka, T., YOKOYAMA, T., Ohta, K., Suzuki, S., Warita, K., Jamal, M., Wang, Z., Ueki, M., Liu, J., et al. (2013) · Journal of Neural Transmission · doi:10.1007/s00702-013-1085-y · Cited by 3
Guo, W., Zhang, W., Zhang, J., Li, Z., & Zhu, W. (2023) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2023.111731 · Cited by 4
Brydevall, M., Albertella, L., Christensen, E., Suo, C., Yücel, M., & Lee, R. S. C. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.03.004 · Cited by 3
Koob, G. F., Arends, M. A., McCracken, M. L., & Moal, M. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816990-2.00001-6 · Cited by 4
Aberrant Reward Anticipating and Processing in Abstinent Heroin Addicts
Li, J., & Yao, H. (2023) · IEEE Transactions on Computational Social Systems · doi:10.1109/tcss.2023.3290969 · Cited by 3
Early Life Adversity as a Risk Factor for Alcohol Use Disorder
Schwandt, M. L. (2023) · Springer eBooks · doi:10.1007/978-3-031-32483-3_34 · Cited by 3
Tobacco and Positron-Emission Tomography (PET) of the Dopaminergic System: A Review of Human Studies
Chukwueke, C. C., & Foll, B. L. (2019) · Neuroscience of Nicotine · doi:10.1016/b978-0-12-813035-3.00014-9 · Cited by 4
Appetitive Motivation and Regulatory Processes in Adolescent Ketamine Users
Chang, H.-H., Huang, C.-L., & Ho, M. (2021) · Substance Use & Misuse · doi:10.1080/10826084.2021.1942055 · Cited by 3
Riondato, M., & Eckelman, W. C. (2016) · Springer eBooks · doi:10.1007/978-3-319-31614-7_4 · Cited by 3
Joseph, J. E., Bustos, N., Crum, K. I., Flanagan, J. C., Baker, N. L., Hartwell, K. J., Maria, M. M. M., Brady, K. T., & McRae‐Clark, A. L. (2022) · Comprehensive Psychoneuroendocrinology · doi:10.1016/j.cpnec.2022.100150 · Cited by 3
Metadata
- Authors
- Volkow, N. D., Wang, G.-J., Fowler, J. S., & Tomasi, D.
- Affiliations
- National Institutes of Health (US)
- Brookhaven National Laboratory (US)
- Venue
- Annual Review of Pharmacology and Toxicology
- Publisher
- Annual Reviews
- Published
- 2012-02-10
- Volume
- 52
- Issue
- 1
- Pages
- 321-336
- ISSN
- 0362-1642 (ISSN-L)
- 1545-4304
- PMC
- PMC3477468
- OpenAlex
- W2111986556
- Cited by
- 592
- References
- 91
- Citations by year
- 2026: 28 · 2025: 47 · 2024: 18 · 2023: 28 · 2022: 28 · 2021: 24 · 2020: 50 · 2019: 42 · 2018: 46 · 2017: 42 · 2016: 58 · 2015: 59 · 2014: 52 · 2013: 50 · 2012: 19
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Annual Review of Pharmacology and Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism (ZIAAA000550)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- addiction, substance use disorders, dopamine, reward systems, brain circuits, chronic drug use, social stress, developmental trajectories, genetic background, memory, executive function, motivation, addiction prevention, addiction treatment
- MeSH terms
- Affect, Brain, Dopamine, Humans, Memory, Stress, Psychological, Behavior, Addictive, Substance-Related Disorders, Executive Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
