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Addiction Circuitry in the Human Brain
Open accessAbstract
A major challenge in understanding substance-use disorders lies in uncovering why some individuals become addicted when exposed to drugs, whereas others do not. Although genetic, developmental, and environmental factors are recognized as major contributors to a person's risk of becoming addicted, the neurobiological processes that underlie this vulnerability are still poorly understood. Imaging studies suggest that individual variations in key dopamine-modulated brain circuits, including circuits involved in reward, memory, executive function, and motivation, contribute to some of the differences in addiction vulnerability. A better understanding of the main circuits affected by chronic drug use and the influence of social stressors, developmental trajectories, and genetic background on these circuits is bound to lead to a better understanding of addiction and to more effective strategies for the prevention and treatment of substance-use disorders.
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“Reductions in executive functions have considered both as vulnerability factors and consequences of addictive behaviors including substance-use disorders (Volkow et al., 2012).”
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“The primary subcortical brain target is the nucleus accumbens (NAc) which is considered the center of the reward circuitry and heavily implicated in substance use and craving [18–22].”
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Citations
Cites
The Brain's Default Network: Anatomy, Function, and Relevance to Disease
Buckner, R. L., Andrews‐Hanna, J. R., & Schacter, D. L. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.011 · Cited by 9,761
Di Chiara, G., & Imperato, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5274 · Cited by 4,733
Bardo, M. T., & Hammer, R. P. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90226-e · Cited by 3,229
Wandering minds: the default network and stimulus-independent thought
Mason, M. F., Norton, M. I., Van Horn, J. D., Wegner, D. M., Grafton, S. T., & Macrae, C. N. (2007) · Science · doi:10.1126/science.1131295 · Cited by 2,792
Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667
Self-citationThe debate over dopamine’s role in reward: the case for incentive salience
Berridge, K. C. (2007) · Psychopharmacology · doi:10.1007/s00213-006-0578-x · Cited by 2,347
A default mode of brain function: a brief history of an evolving idea
Raichle, M. E., & Snyder, A. Z. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.02.041 · Cited by 2,173
Limbic Activation During Cue-Induced Cocaine Craving
Childress, A. R., Mozley, P. D., McElgin, W., Fitzgerald, J., Reivich, M., & O’Brien, C. P. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.1.11 · Cited by 1,513
The primate basal ganglia: Parallel and integrative networks
Haber, S. N. (2003) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2003.10.003 · Cited by 1,479
Synaptic plasticity and addiction
Kauer, J. A., & Malenka, R. C. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2234 · Cited by 1,397
Research works printed but not linked: 3
- 10.1176/appi.ajp.164.4.622 · DOI · Paper page
- Wang GJ, 2010, J. Nucl. Med., 51, 269
- Hommer DW, 1999, Alcohol Res. Health, 23, 187
Cited by
Sorted by citations
Brand, M., Young, K. S., Laier, C., Wölfling, K., & Potenza, M. N. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.033 · Cited by 2,416
“…that both internal and xternal stimuli may be conditioned within an addiction process vioral Reviews 71 (2016) 252–266 (Kalivas and Volkow, 2005; Volkow et al., 2012) and may then trigger affective and cognitive processes resulting in the decision to use the Internet application/site of choice.”
Brand, M., Wegmann, E., Stark, R., Müller, A., Wölfling, K., Robbins, T. W., & Potenza, M. N. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.06.032 · Cited by 2,126
“Reductions in stimuli-specific inhibitory control may develop based on cue-reactivity and craving and be accompanied by functional brain changes in addiction-related circuits (Ersche et al., 2012; Koob & Volkow, 2010; Volkow & Morales, 2015; Volkow et al., 2012).”
The behavioral economics of substance use disorders: reinforcement pathologies and their repair
Bickel, W. K., Johnson, M. W., Koffarnus, M. N., MacKillop, J., & Murphy, J. G. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153724 · Cited by 655
The clinical significance of drug craving
Tiffany, S. T., & Wray, J. M. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06298.x · Cited by 556
Volkow, N. D., & Blanco, C. (2023) · World psychiatry · doi:10.1002/wps.21073 · Cited by 503
Self-citationObesity and the brain: how convincing is the addiction model?
Ziauddeen, H., Farooqi, I. S., & Fletcher, P. C. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3212 · Cited by 462
Model-based and model-free Pavlovian reward learning: Revaluation, revision, and revelation
Dayan, P., & Berridge, K. C. (2014) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/s13415-014-0277-8 · Cited by 357
What is the evidence for “food addiction?” A systematic review
Gordon, E., Ariel-Donges, A., Bauman, V., & Merlo, L. (2018) · Nutrients · doi:10.3390/nu10040477 · Cited by 316
Burkett, J. P., & Young, L. J. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2794-x · Cited by 307
Cooper, S., Robison, A. J., & Mazei‐Robison, M. S. (2017) · Neurotherapeutics · doi:10.1007/s13311-017-0525-z · Cited by 293
Zhang, M. X., & Wu, A. M. S. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2020.106552 · Cited by 265
Krueger, R. F., Hobbs, K. A., Conway, C., Dick, D. M., Dretsch, M. N., Eaton, N. R., Forbes, M. K., Forbush, K. T., Keyes, K. M., Latzman, R. D., et al. (2021) · World Psychiatry · doi:10.1002/wps.20844 · Cited by 294
Definition of Substance and Non-substance Addiction
Zou, Z., Wang, H., d’Oleire Uquillas, F., Wang, X., Ding, J., & Chen, H. (2017) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-10-5562-1_2 · Cited by 252
Compulsivity in obsessive–compulsive disorder and addictions
Figee, M., Pattij, T., Willuhn, I., Luigjes, J., van den Brink, W., Goudriaan, A. E., Potenza, M. N., Robbins, T. W., & Denys, D. A. J. P. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.12.003 · Cited by 258
Neural substrates of cue reactivity: association with treatment outcomes and relapse
Courtney, K. E., Schacht, J. P., Hutchison, K. E., Roche, D. J. O., & Ray, L. A. (2015) · Addiction Biology · doi:10.1111/adb.12314 · Cited by 256
Localization of PPAR isotypes in the adult mouse and human brain
Warden, A. S., Truitt, J., Merriman, M., Ponomareva, O. Y., Jameson, K. G., Ferguson, L. B., Mayfield, R. D., & Harris, R. A. (2016) · Scientific Reports · doi:10.1038/srep27618 · Cited by 243
Biomarkers in Parkinson’s disease (recent update)
Sharma, S. K., Moon, C. S., Khogali, A., Haidous, A., Chabenne, A., Ojo, C., Jelebinkov, M., Kurdi, Y., & Ebadi, M. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.06.005 · Cited by 249
Circuitry of self-control and its role in reducing addiction
Tang, Y.-Y., Posner, M. I., Rothbart, M. K., & Volkow, N. D. (2015) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2015.06.007 · Cited by 236
Self-citationHsu, D. T., Kirouac, G. J., Zubieta, J.-K., & Bhatnagar, S. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00073 · Cited by 238
Hall, W., Carter, A., & Forlini, C. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00126-6 · Cited by 259
Striatocortical pathway dysfunction in addiction and obesity: differences and similarities
Tomasi, D. G., & Volkow, N. D. (2012) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2012.735642 · Cited by 236
Self-citationVolkow, N. D., Wang, G., Telang, F., Fowler, J. S., Alexoff, D. L., Logan, J., Jayne, M. C., Wong, C., & Tomasi, D. G. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411228111 · Cited by 230
Self-citationChapter 1. Neurocircuitry of Addiction
Koob, G. F., & Volkow, N. D. (2021) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615373970.kb01 · Cited by 236
Self-citationIntracranial Self-Stimulation to Evaluate Abuse Potential of Drugs
Negus, S. S., & Miller, L. L. (2014) · Pharmacological Reviews · doi:10.1124/pr.112.007419 · Cited by 216
Neuropathology of substance use disorders
Cadet, J. L., Bisagno, V., & Milroy, C. M. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1221-7 · Cited by 217
Brain size, sex, and the aging brain
Jäncke, L., Mérillat, S., Liem, F., & Hänggi, J. (2014) · Human Brain Mapping · doi:10.1002/hbm.22619 · Cited by 204
Social “wanting” dysfunction in autism: neurobiological underpinnings and treatment implications
Kohls, G., Chevallier, C., Troiani, V., & Schultz, R. T. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-10 · Cited by 197
Musical pleasure and reward: mechanisms and dysfunction
Zatorre, R. J. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12677 · Cited by 214
The role of reward circuitry and food addiction in the obesity epidemic: An update
Leigh, S.-J., & Morris, M. J. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2016.12.013 · Cited by 191
The research domain criteria framework: The case for anterior cingulate cortex
Holroyd, C. B., & Umemoto, A. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.09.021 · Cited by 187
Structural and functional correlates of smartphone addiction
Horvath, J., Mundinger, C., Schmitgen, M. M., Wolf, N. D., Sambataro, F., Hirjak, D., Kubera, K. M., Koenig, J., & Christian Wolf, R. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2020.106334 · Cited by 190
Kaye, W. H., Wierenga, C. E., Bailer, U. F., Simmons, A. N., Wagner, A., & Bischoff‐Grethe, A. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.002 · Cited by 171
Caffeine Increases Striatal Dopamine D2/D3 Receptor Availability in the Human Brain
Volkow, N. D., Wang, G.-J., Logan, J., Alexoff, D., Fowler, J. S., Thanos, P. K., Wong, C., Casado, V, Ferre, S., & Tomasi, D. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.46 · Cited by 163
Self-citationDual role of nicotine in addiction and cognition: A review of neuroimaging studies in humans
Jasinska, A. J., Zorick, T. S., Brody, A. L., & Stein, E. A. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.02.015 · Cited by 170
Davis, C. A. (2016) · Appetite · doi:10.1016/j.appet.2016.11.001 · Cited by 155
Dalsgaard, S., Mortensen, P. B., Frydenberg, M., & Thomsen, P. H. (2014) · Addictive Behaviors · doi:10.1016/j.addbeh.2013.09.002 · Cited by 144
Compulsivity in anorexia nervosa: a transdiagnostic concept
Godier-McBard, L. R., & Park, R. J. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.00778 · Cited by 157
Chandler, D. J., Waterhouse, B. D., & Gao, W. (2014) · Frontiers in Neural Circuits · doi:10.3389/fncir.2014.00053 · Cited by 143
Deep Brain Stimulation Surgery for Alcohol Addiction
Voges, J., Müller, U., Bogerts, B., Münte, T. F., & Heinze, H. (2012) · World Neurosurgery · doi:10.1016/j.wneu.2012.07.011 · Cited by 146
Gender-related Differences in Food Craving and Obesity.
Hallam, J., Boswell, R. G., DeVito, E. E., & Hedy Kober, A. (2016) · PubMed · Cited by 156
Buisman‐Pijlman, F. T. A., Sumracki, N. M., Gordon, J. J., Hull, P. R., Carter, C. S., & Tops, M. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.09.005 · Cited by 147
The importance of nutrition in aiding recovery from substance use disorders: a review
Jeynes, K. D., & Gibson, E. L. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.07.006 · Cited by 142
Wilcox, M. V., Carlson, V. C. C., Sherazee, N., Sprow, G. M., Bock, R., Thiele, T. E., Lovinger, D. M., & Alvarez, V. A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.230 · Cited by 140
Witteman, J., Post, H., Tarvainen, M. P., de Bruijn, A., Perna, E. B. D. S. F., Ramaekers, J. G., & Wiers, R. W. H. J. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4027-6 · Cited by 151
Immunomodulatory Effects Mediated by Dopamine
Arreola, R., Álvarez-Herrera, S., Pérez‐Sánchez, G., Becerril‐Villanueva, E., Cruz-Fuentes, C. S., Flores-Gutiérrez, E. O., Garcés-Alvarez, M. E., de la Cruz-Aguilera, D. L., Medina‐Rivero, E., Hurtado‐Alvarado, G., et al. (2016) · Journal of Immunology Research · doi:10.1155/2016/3160486 · Cited by 141
Stimulant-induced dopamine increases are markedly blunted in active cocaine abusers
Volkow, N. D., Tomasi, D., Wang, G.-J., Logan, J., Alexoff, D. L., Jayne, M., Fowler, J. S., Wong, C., Yin, P., & Du, C. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.58 · Cited by 134
Self-citation21st century neurobehavioral theories of decision making in addiction: Review and evaluation
Bickel, W. K., Mellis, A. M., Snider, S. E., Athamneh, L. N., Stein, J. S., & Pope, D. A. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2017.09.009 · Cited by 134
Krasnova, I. N., Chiflikyan, M., Justinová, Z., McCoy, M. T., Ladenheim, B., Jayanthi, S., Quintero, C. M., Brannock, C., Barnes, C., Adair, J. E., et al. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.05.009 · Cited by 134
Ray, N. J., Miyasaki, J. M., Zurowski, M., Ko, J. H., Cho, S. S., Pellecchia, G., Antonelli, F., Houle, S., Lang, A. E., & Strafella, A. P. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.06.021 · Cited by 131
A neural network for information seeking
White, J. K., Bromberg-Martin, E. S., Heilbronner, S. R., Zhang, K., Pai, J., Haber, S. N., & Monosov, I. E. (2019) · Nature Communications · doi:10.1038/s41467-019-13135-z · Cited by 129
Recent advances in quantitative neuroproteomics
Craft, G. E., Chen, A., & Nairn, A. C. (2013) · Methods · doi:10.1016/j.ymeth.2013.04.008 · Cited by 127
Efficacy of invasive and non-invasive brain modulation interventions for addiction
Luigjes, J., Segrave, R., de Joode, N., Figee, M., & Denys, D. (2019) · Neuropsychology Review · doi:10.1007/s11065-018-9393-5 · Cited by 125
Mahoney, J. J., Hanlon, C. A., Marshalek, P. J., Rezai, A. R., & Krinke, L. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.117149 · Cited by 121
The thalamus in drug addiction: from rodents to humans
Huang, A., Mitchell, J. A., Haber, S. N., Alia‐Klein, N., & Goldstein, R. Z. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2017.0028 · Cited by 120
The Genetics of Substance Dependence
Wang, J.-C., Kapoor, M., & Goate, A. (2012) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090711-163844 · Cited by 125
Gluskin, B. S., & Mickey, B. J. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.22 · Cited by 119
Remembering the forgotten non-communicable diseases
Lopez, A. D., Williams, T. N., Levin, A., Tonelli, M., Singh, J. A., Burney, P. G., Rehm, J., Volkow, N. D., Koob, G., & Ferri, C. P. (2014) · BMC Medicine · doi:10.1186/s12916-014-0200-8 · Cited by 108
Self-citationYu, J. J., Kim, H., & Hay, I. (2013) · Computers in Human Behavior · doi:10.1016/j.chb.2013.06.045 · Cited by 115
Campos, A., Port, J. D., & Acosta, A. J. (2022) · Brain Sciences · doi:10.3390/brainsci12040431 · Cited by 126
Ceccarini, J., Hompes, T., Verhaeghen, A., Casteels, C., Peuskens, H., Bormans, G., Claes, S., & Van Laere, K. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.0849-13.2014 · Cited by 111
Overlapping patterns of brain activation to food and cocaine cues in cocaine abusers
Tomasi, D. G., Wang, G., Wang, R., Caparelli, E. C., Logan, J., & Volkow, N. D. (2014) · Human Brain Mapping · doi:10.1002/hbm.22617 · Cited by 115
Self-citationNeuropsychological Consequences of Chronic Drug Use: Relevance to Treatment Approaches
Cadet, J. L., & Bisagno, V. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2015.00189 · Cited by 110
Görlich, A., Antolin‐Fontes, B., Ables, J. L., Frahm, S., Ślimak, M. A., Dougherty, J. D., & Ibáñez-Tallon, I. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1313103110 · Cited by 119
YOUNG, K. S., & Brand, M. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01853 · Cited by 117
Zack, M., Featherstone, R. E., Mathewson, S., & Fletcher, P. J. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00036 · Cited by 108
Physician Education in Addiction Medicine
Wood, E., Samet, J. H., & Volkow, N. D. (2013) · JAMA · doi:10.1001/jama.2013.280377 · Cited by 106
Self-citationDeleuze, J., Nuyens, F., Rochat, L., Rothen, S., Maurage, P., & Billieux, J. (2017) · Journal of Behavioral Addictions · doi:10.1556/2006.6.2017.074 · Cited by 102
Sympathoneural and Adrenomedullary Responses to Mental Stress
Carter, J. R., & Goldstein, D. S. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140030 · Cited by 119
Nusslock, R., Walden, K., & Harmon-Jones, E. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.06.004 · Cited by 95
PET imaging reveals brain functional changes in internet gaming disorder
Tian, M., Chen, Q., Zhang, Y., Du, F., Hou, H., Chao, F., & Zhang, H. (2014) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-014-2708-8 · Cited by 108
Villalba, R. M., & Smith, Y. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.07.011 · Cited by 97
The Role of Adenosine Receptors in Psychostimulant Addiction
Ballesteros‐Yáñez, I., Castillo, C. A., Merighi, S., & Gessi, S. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00985 · Cited by 99
Reichelt, A. C. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00189 · Cited by 101
Neural and Behavioral Effects of a Novel Mu Opioid Receptor Antagonist in Binge-Eating Obese People
Cambridge, V. C., Ziauddeen, H., Nathan, P. J., Subramaniam, N., Dodds, C., Chamberlain, S. R., Koch, A., Maltby, K., Skeggs, A. L., Napolitano, A., et al. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.10.022 · Cited by 92
Effects of Age and Sex on Subcortical Volumes
Wang, Y., Xu, Q., Luo, J., Hu, M., & Zuo, C. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00259 · Cited by 95
Unexpected global impact of VTA dopamine neuron activation as measured by opto-fMRI
Lohani, S., Poplawsky, A. J., Kim, S.-G., & Moghaddam, B. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.102 · Cited by 89
Luca, M. A. D., Bimpisidis, Z., Melis, M., Marti, M., Caboni, P., Valentini, V., Margiani, G., Pintori, N., Polis, I. Y., Marsicano, G., et al. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.08.041 · Cited by 88
Li, X., Du, L., Sahlem, G. L., Badran, B. W., Henderson, S., & George, M. S. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.02.002 · Cited by 90
Cheetham, A., Allen, N. B., Whittle, S., Simmons, J. G., Yücel, M., & Lubman, D. I. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3483-8 · Cited by 89
Food Cues and Obesity: Overpowering Hormones and Energy Balance Regulation
Belfort-DeAguiar, R., & Seo, D. (2018) · Current Obesity Reports · doi:10.1007/s13679-018-0303-1 · Cited by 84
The Neuroscience of Adolescence
Galván, A. (2017) · Cambridge University Press eBooks · doi:10.1017/9781316106143 · Cited by 82
Dopamine Receptor Activation Increases HIV Entry into Primary Human Macrophages
Gaskill, P. J., Yano, H., Kalpana, G. V., Javitch, J. A., & Berman, J. W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108232 · Cited by 82
Park, K., Volkow, N. D., Pan, Y., & Du, C. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.1935-13.2013 · Cited by 83
Self-citationShumay, E., Fowler, J. S., Wang, G.-J., Logan, J., Alia-Klein, N., Goldstein, R. Z., Maloney, T., Wong, C., & Volkow, N. D. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.11 · Cited by 79
Self-citationCadet, J. L., Brannock, C., Krasnova, I. N., Jayanthi, S., Ladenheim, B., McCoy, M. T., Walther, D. M., Godino, A., Pirooznia, M., & Lee, R. S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.48 · Cited by 79
The Functional Anatomy of Impulse Control Disorders
Probst, C. C., & van Eimeren, T. (2013) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-013-0386-8 · Cited by 77
Weber, S. C., Beck‐Schimmer, B., Kajdi, M.-E., Müller, D., Tobler, P. N., & Quednow, B. B. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.113 · Cited by 76
Altered default mode, fronto-parietal and salience networks in adolescents with Internet addiction
Wang, L., Shen, H., Lei, Y., Zeng, L., Cao, F., Su, L., Zheng, Y., Yao, S., & Hu, D. (2017) · Addictive Behaviors · doi:10.1016/j.addbeh.2017.01.021 · Cited by 77
Reducing Ventral Tegmental Dopamine D2 Receptor Expression Selectively Boosts Incentive Motivation
de Jong, J. W., Roelofs, T. J. M., Mol, F., Hillen, A. E. J., Meijboom, K. E., Luijendijk, M. C. M., van der Eerden, H. A. M., Garner, K. M., Vanderschuren, L. J. M. J., & Adan, R. A. H. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.60 · Cited by 77
Ravichandran, S., Bhatt, R. R., Pandit, B., Osadchiy, V., Alaverdyan, A., Vora, P. P., Stains, J., Naliboff, B. D., Mayer, E. A., & Gupta, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-83116-0 · Cited by 82
Neurobiological findings related to I nternet use disorders
Park, B., Han, D. H., & Roh, S. (2016) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12422 · Cited by 74
Aberrant mesolimbic dopamine–opiate interaction in obesity
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Metadata
- Authors
- Volkow, N. D., Wang, G.-J., Fowler, J. S., & Tomasi, D.
- Affiliations
- National Institutes of Health (US)
- Brookhaven National Laboratory (US)
- Venue
- Annual Review of Pharmacology and Toxicology
- Publisher
- Annual Reviews
- Published
- 2012-02-10
- Volume
- 52
- Issue
- 1
- Pages
- 321-336
- ISSN
- 0362-1642 (ISSN-L)
- 1545-4304
- PMC
- PMC3477468
- OpenAlex
- W2111986556
- Cited by
- 592
- References
- 91
- Citations by year
- 2026: 28 · 2025: 47 · 2024: 18 · 2023: 28 · 2022: 28 · 2021: 24 · 2020: 50 · 2019: 42 · 2018: 46 · 2017: 42 · 2016: 58 · 2015: 59 · 2014: 52 · 2013: 50 · 2012: 19
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Annual Review of Pharmacology and Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism (ZIAAA000550)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- addiction, substance use disorders, dopamine, reward systems, brain circuits, chronic drug use, social stress, developmental trajectories, genetic background, memory, executive function, motivation, addiction prevention, addiction treatment
- MeSH terms
- Affect, Brain, Dopamine, Humans, Memory, Stress, Psychological, Behavior, Addictive, Substance-Related Disorders, Executive Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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