Understanding the Chemical Exposome During Fetal Development and Early Childhood: A Review

Complementing the Genome with an “Exposome”: The Outstanding Challenge of Environmental Exposure Measurement in Molecular Epidemiology

Wild, C. P. (2005) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0456 · Cited by 2,562 · see citing works

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Fenton, S. E., Ducatman, A., Boobis, A., DeWitt, J. C., Lau, C., Ng, C., Smith, J. S., & Roberts, S. M. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4890 · Cited by 2,445 · see citing works

Evolution of the immune system in humans from infancy to old age

Simon, A. K., Hollander, G. A., & McMichael, A. (2015) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2014.3085 · Cited by 1,796 · see citing works

Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects

Rubin, B. S. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2011.05.002 · Cited by 1,420 · see citing works

The exposome: from concept to utility

Wild, C. P. (2012) · International Journal of Epidemiology · doi:10.1093/ije/dyr236 · Cited by 1,416 · see citing works

A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome

Perez-Muñoz, M. E., Arrieta, M.-C., Ramer-Tait, A. E., & Walter, J. (2017) · Microbiome · doi:10.1186/s40168-017-0268-4 · Cited by 1,096 · see citing works

Some traditional herbal medicines, some mycotoxins, naphthalene and styrene.

(2002) · PubMed Central · Cited by 1,079 · see citing works

Early Life Exposure to Endocrine Disrupting Chemicals and Childhood Obesity and Neurodevelopment

Braun, J. M. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.186 · Cited by 837 · see citing works

OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies

Roth, M. E., Obaidat, A., & Hagenbuch, B. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01724.x · Cited by 764 · see citing works

Trophoblast organoids as a model for maternal–fetal interactions during human placentation

Turco, M. Y., Gardner, L., Kay, R. G., Hamilton, R. S., Prater, M., Hollinshead, M. S., McWhinnie, A., Esposito, L., Fernando, R. C., Skelton, H. E., et al. (2018) · Nature · doi:10.1038/s41586-018-0753-3 · Cited by 700 · see citing works

Integrated omics: tools, advances and future approaches

Misra, B. B., Langefeld, C., Olivier, M., & Cox, L. A. (2019) · Journal of Molecular Endocrinology · doi:10.1530/jme-18-0055 · Cited by 686 · see citing works

Metabolism of phthalates in humans

Frederiksen, H., Skakkebaek, N. E., & Andersson, A. (2007) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200600243 · Cited by 652 · see citing works

Development of the gut microbiota in infancy and its impact on health in later life

Tanaka, M., & Nakayama, J. (2017) · Allergology International · doi:10.1016/j.alit.2017.07.010 · Cited by 639 · see citing works

Effects of trichothecene mycotoxins on eukaryotic cells: A review

Rocha, O., Ansari, K. I., & Doohan, F. M. (2005) · Food Additives & Contaminants · doi:10.1080/02652030500058403 · Cited by 591 · see citing works

Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems

Sifakis, S., Androutsopoulos, V. P., Tsatsakis, A. M., & Spandidos, D. A. (2017) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2017.02.024 · Cited by 439 · see citing works

Endocrine disruptors and obesity

Heindel, J. J., Newbold, R. R., & Schug, T. T. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.163 · Cited by 429 · see citing works

Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta

Haider, S., Meinhardt, G., Saleh, L., Kunihs, V., Gamperl, M., Kaindl, U., Ellinger, A., Burkard, T. R., Fiala, C., Pollheimer, J., et al. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.07.004 · Cited by 417 · see citing works

Some industrial chemicals.

McManus, M. (1994) · PubMed · Cited by 386 · see citing works

Occurrence and toxicity of a fusarium mycotoxin, zearalenone

Rai, A., Das, M., & Tripathi, A. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1655388 · Cited by 380 · see citing works

Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants

Calafat, A. M., Weuve, J., Ye, X., Jia, L. T., Hu, H., Ringer, S., Huttner, K., & Hauser, R. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800265 · Cited by 374 · see citing works

Environmental Phthalate Exposure and Preterm Birth

Ferguson, K. K., McElrath, T. F., & Meeker, J. D. (2013) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2013.3699 · Cited by 362 · see citing works

Data analysis strategies for targeted and untargeted LC-MS metabolomic studies: Overview and workflow

Gorrochategui, E., Jaumot, J., Lacorte, S., & Tauler, R. (2016) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2016.07.004 · Cited by 352 · see citing works

An Updated Review of Ciguatera Fish Poisoning: Clinical, Epidemiological, Environmental, and Public Health Management

Friedman, M., Fernandez, M., Backer, L. C., DICKEY, R. W., Bernstein, J. N., Schrank, K. S., Kibler, S. R., Stephan, W., Gribble, M. O., Bienfang, P. K., et al. (2017) · Marine Drugs · doi:10.3390/md15030072 · Cited by 347 · see citing works

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS

Bian, Y., Zheng, R., Bayer, F. P., Wong, C. J., Chang, Y.-C., Meng, C., Zolg, D. P., Reinecke, M., Zecha, J., Wiechmann, S., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13973-x · Cited by 342 · see citing works

Neurotoxicity in acute and repeated organophosphate exposure

Naughton, S. X., & Terry, A. V. (2018) · Toxicology · doi:10.1016/j.tox.2018.08.011 · Cited by 335 · see citing works

An Introduction to Terminology and Methodology of Chemical Synergy—Perspectives from Across Disciplines

Roell, K. R., Reif, D. M., & Motsinger‐Reif, A. A. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00158 · Cited by 299 · see citing works

Advances in mass spectrometry-based metabolomics for investigation of metabolites

Ren, J., Zhang, A., Kong, L. D., & Wang, X. (2018) · RSC Advances · doi:10.1039/c8ra01574k · Cited by 298 · see citing works

Low Doses of Bisphenol A Promote Human Seminoma Cell Proliferation by Activating PKA and PKG via a Membrane G-Protein–Coupled Estrogen Receptor

Bouskine, A., Nebout, M., Brücker-Davis, F., Benahmed, M., & Fénichel, P. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0800367 · Cited by 284 · see citing works

Dry cleaning, some chlorinated solvents and other industrial chemicals.

(1995) · PubMed Central · Cited by 278 · see citing works

Placenta-on-a-chip: a novel platform to study the biology of the human placenta

Lee, J. S., Romero, R. J., Han, Y. M., Kim, H. C., Kim, C. J., Hong, J., & Huh, D. (2015) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2015.1038518 · Cited by 272 · see citing works

Human placental explants in culture: Approaches and assessments

Miller, R. K., Genbačev, O., Turner, M. A., Aplin, J., Caniggia, I., & Huppertz, B. (2004) · Placenta · doi:10.1016/j.placenta.2004.10.002 · Cited by 257 · see citing works

A microphysiological model of the human placental barrier

Blundell, C., Tess, E. R., Schanzer, A., Coutifaris, C., Su, E. J., Parry, S. I., & Huh, D. (2016) · Lab on a Chip · doi:10.1039/c6lc00259e · Cited by 253 · see citing works

Occurrence of and Dietary Exposure to Parabens in Foodstuffs from the United States

Liao, C., Liu, F., & Kannan, K. (2013) · Environmental Science & Technology · doi:10.1021/es400724s · Cited by 249 · see citing works

Potential estrogenic effect(s) of parabens at the prepubertal stage of a postnatal female rat model

Vo, T. T. B., Yoo, Y., Choi, K., & Jeung, E. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.01.013 · Cited by 245 · see citing works

Parental Transfer of Polybrominated Diphenyl Ethers (PBDEs) and Thyroid Endocrine Disruption in Zebrafish

Yu, L., Lam, J. C. W., Guo, Y., Wu, R. S. S., Lam, P. K. S., & Zhou, B. (2011) · Environmental Science & Technology · doi:10.1021/es2026592 · Cited by 208 · see citing works

Ontogeny of drug metabolizing enzymes in the neonate

Blake, M. J., Castro, L., Leeder, J. S., & Kearns, G. L. (2005) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2004.11.001 · Cited by 200 · see citing works

Syncytin-2 Plays an Important Role in the Fusion of Human Trophoblast Cells

Vargas, A., Moreau, J., Landry, S., Bellego, F. L., Toufaily, C., Rassart, É., Lafond, J., & Barbeau, B. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.07.025 · Cited by 200 · see citing works

The Human Placental Perfusion Model: A Systematic Review and Development of a Model to Predict In Vivo Transfer of Therapeutic Drugs

Hutson, J. R., Garcia-Bournissen, F., Davis, A., & Koren, G. (2011) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2011.66 · Cited by 199 · see citing works

P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages

Mathias, A. A., Hitti, J. E., & Unadkat, J. D. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00173.2005 · Cited by 191 · see citing works

Environmental mixtures of nanomaterials and chemicals: The Trojan-horse phenomenon and its relevance for ecotoxicity

Naasz, S., Altenburger, R., & Kühnel, D. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.04.180 · Cited by 182 · see citing works

Placental Drug Transport‐on‐a‐Chip: A Microengineered In Vitro Model of Transporter‐Mediated Drug Efflux in the Human Placental Barrier

Blundell, C., Yi, Y., Ma, L., Tess, E. R., Farrell, M. J., Georgescu, A., Aleksunes, L. M., & Huh, D. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700786 · Cited by 178 · see citing works

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

Evseenko, D. A., Paxton, J. W., & Keelan, J. A. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00630.2005 · Cited by 175 · see citing works

Environmental toxicants in breast milk of Norwegian mothers and gut bacteria composition and metabolites in their infants at 1 month

Iszatt, N., Janssen, S., Lenters, V. C., Dahl, C., Stigum, H., Knight, R. D., Mandal, S., Peddada, S., González, A., Midtvedt, T., et al. (2019) · Microbiome · doi:10.1186/s40168-019-0645-2 · Cited by 173 · see citing works

Molecular mechanism(s) of endocrine‐disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors

Lee, H., Jeung, E., Cho, M., Kim, T., Leung, P. C. K., & Choi, K. (2013) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2012.01649.x · Cited by 171 · see citing works

Mechanisms of Fetal T Cell Tolerance and Immune Regulation

Rackaityte, E., & Halkias, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00588 · Cited by 171 · see citing works

Low risk posed by engineered and incidental nanoparticles in drinking water

Westerhoff, P. K., Atkinson, A. J., Fortner, J. D., Wong, M. S., Zimmerman, J. B., Gardea-Torresdey, J. L., Ranville, J. F., & Herckès, P. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0217-9 · Cited by 158 · see citing works

Medication Use in the Neonatal Intensive Care Unit and Changes from 2010 to 2018

Stark, A., Smith, P. B., Hornik, C. P. V., Zimmerman, K. O., Hornik, C. D., Pradeep, S., Clark, R. H., Benjamin, D. K., Laughon, M. M., & Greenberg, R. G. (2021) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2021.08.075 · Cited by 153 · see citing works

Nanoparticle Transport Across the Placental Barrier: Pushing the Field Forward!

Muoth, C., Aengenheister, L., Kucki, M., Wick, P., & Buerki-Thurnherr, T. (2016) · Nanomedicine · doi:10.2217/nnm-2015-0012 · Cited by 146 · see citing works

Function and organization of the human cytosolic sulfotransferase (SULT) family

Coughtrie, M. W. H. (2016) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2016.05.005 · Cited by 142 · see citing works

An overview of the toxic effect of potential human carcinogen Microcystin-LR on testis

Lone, Y., Koiri, R. K., & Bhide, M. (2015) · Toxicology Reports · doi:10.1016/j.toxrep.2015.01.008 · Cited by 141 · see citing works

Aflatoxin B1 Transfer and Metabolism in Human Placenta

Partanen, H., El-Nezami, H. S., Leppänen, J. M., Myllynen, P. K., Woodhouse, H. J., & Vähäkangas, K. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp257 · Cited by 139 · see citing works

Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies

Bongaerts, E., Nawrot, T. S., Pee, T. V., Ameloot, M. M., & Bové, H. (2020) · Particle and Fibre Toxicology · doi:10.1186/s12989-020-00386-8 · Cited by 136 · see citing works

Presence of mycotoxin in commercial infant formulas and baby foods from Italian market

Juan, C., Raiola, A., Mañes, J., & Ritieni, A. (2013) · Food Control · doi:10.1016/j.foodcont.2013.10.036 · Cited by 132 · see citing works

The early-life exposome: Description and patterns in six European countries

Tamayo, I., Maître, L., Thomsen, C., Nieuwenhuijsen, M. J., Chatzi, L., Siroux, V., Aasvang, G. M., Agier, L., Andrušaitytė, S., Casas, M., et al. (2018) · Environment International · doi:10.1016/j.envint.2018.11.067 · Cited by 132 · see citing works

Exposure Levels of Environmental Endocrine Disruptors in Mother-Newborn Pairs in China and Their Placental Transfer Characteristics

Li, L.-X., Chen, L., Meng, X., Chen, B., Chen, S., Zhao, Y., Zhao, L.-F., Liang, Y., & Zhang, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062526 · Cited by 126 · see citing works

Human biomonitoring initiative (HBM4EU) - Strategy to derive human biomonitoring guidance values (HBM-GVs) for health risk assessment

Apel, P., Rousselle, C., Lange, R., Sissoko, F., Kolossa‐Gehring, M., & Ougier, E. (2020) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2020.113622 · Cited by 125 · see citing works

Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Bhatt, D. K., Mehrotra, A., Gaedigk, A., Chapa, R., Basit, A., Zhang, H., Choudhari, P., Boberg, M., Pearce, R. E., Gaedigk, R., et al. (2018) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1109 · Cited by 124 · see citing works

An update on expression and function of P-gp/ABCB1 and BCRP/ABCG2 in the placenta and fetus

Han, L. W., Gao, C., & Mao, Q. (2018) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2018.1499726 · Cited by 123 · see citing works

An advanced human in vitro co-culture model for translocation studies across the placental barrier

Aengenheister, L., Keevend, K., Muoth, C., Schönenberger, R., Diener, L., Wick, P., & Buerki‐Thurnherr, T. (2018) · Scientific Reports · doi:10.1038/s41598-018-23410-6 · Cited by 121 · see citing works

The Endocrine Disruption of Prenatal Phthalate Exposure in Mother and Offspring

Qian, Y., Shao, H., Ying, X., Huang, W., & Hua, Y. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.00366 · Cited by 121 · see citing works

Environmental Chemicals in Breast Milk and Formula: Exposure and Risk Assessment Implications

Lehmann, G. M., LaKind, J. S., Davis, M. H., Hines, E. P., Marchitti, S. A., Alcala, C. S., & Lorber, M. (2018) · Environmental Health Perspectives · doi:10.1289/ehp1953 · Cited by 117 · see citing works

Placental transfer and metabolism: An overview of the experimental models utilizing human placental tissue

Myllynen, P., & Vähäkangas, K. (2013) · Toxicology in Vitro · doi:10.1016/j.tiv.2012.08.027 · Cited by 115 · see citing works

Transplacental transfer of polycyclic aromatic hydrocarbons in paired samples of maternal serum, umbilical cord serum, and placenta in Shanghai, China

Zhang, X., Li, X., Ye, J., Fang, X., Zhang, X., Lei, B., & Yu, Y. (2016) · Environmental Pollution · doi:10.1016/j.envpol.2016.12.046 · Cited by 115 · see citing works

Recent insights on indirect mechanisms in developmental toxicity of nanomaterials

Dugershaw, B. B., Aengenheister, L., Hansen, S. S. K., ­Hougaard, K. S., & Buerki‐Thurnherr, T. (2020) · Particle and Fibre Toxicology · doi:10.1186/s12989-020-00359-x · Cited by 114 · see citing works

Perfluoroalkyl substances (PFASs) in breast milk from Korea: Time-course trends, influencing factors, and infant exposure

Lee, S., Kim, S., Park, J., Kim, H., Choi, G., Choi, S., Kim, S., Kim, S. Y., Kim, S., Choi, K., et al. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.08.094 · Cited by 112 · see citing works

Expression profiling of human fetal cytosolic sulfotransferases involved in steroid and thyroid hormone metabolism and in detoxification

Stanley, E. L., Hume, R., & Coughtrie, M. W. H. (2005) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2005.06.003 · Cited by 111 · see citing works

Placental control of drug delivery

Al-Enazy, S., Ali, S., Albekairi, N. A., El-Tawil, M., & Rytting, E. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.08.002 · Cited by 110 · see citing works

Fabrication of biomimetic placental barrier structures within a microfluidic device utilizing two-photon polymerization

Mandt, D., Gruber, P., Marković, M., Tromayer, M., Rothbauer, M., Kratz, S. R. A., Ali, S. F., Hoorick, J. V., Holnthoner, W., Mühleder, S., et al. (2018) · International Journal of Bioprinting · doi:10.18063/ijb.v4i2.144 · Cited by 103 · see citing works

Assessment of an in vitro transport model using BeWo b30 cells to predict placental transfer of compounds

Li, H., van Ravenzwaay, B., Rietjens, I. M. C. M., & Louisse, J. (2013) · Archives of Toxicology · doi:10.1007/s00204-013-1074-9 · Cited by 99 · see citing works

An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

Bocato, M. Z., Ximenez, J. P. B., Hoffmann, C., & Barbosa, F. (2019) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2019.1661588 · Cited by 92 · see citing works

Bridging Targeted and Untargeted Mass Spectrometry-Based Metabolomics via Hybrid Approaches

Chen, L., Zhong, F., & Zhu, J. (2020) · Metabolites · doi:10.3390/metabo10090348 · Cited by 90 · see citing works

Environmental contaminants in human milk

Anderson, H. A., & Wolff, M. S. (2000) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/sj.jea.7500133 · Cited by 89 · see citing works

Prenatal exposure to phthalates and neurocognitive development in children at two years of age

Qian, X., Li, J., Xu, S., Wan, Y., Li, Y., Jiang, Y., Zhao, H., Zhou, Y. R., Liao, J., Liu, H., et al. (2019) · Environment International · doi:10.1016/j.envint.2019.105023 · Cited by 88 · see citing works

Developmental and Neurotoxicity of Acrylamide to Zebrafish

Park, J., Samanta, P., Lee, S., Lee, J., Cho, J., Chun, H., Yoon, S., & Kim, W. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073518 · Cited by 87 · see citing works

Piperidine alkaloids: Human and food animal teratogens

Green, B. T., Lee, S. T., Panter, K. E., & Brown, D. R. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.03.049 · Cited by 86 · see citing works

Atropa belladonna neurotoxicity: Implications to neurological disorders

Kwakye, G. F., Jiménez, J., Jiménez, J. A., & Aschner, M. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.04.022 · Cited by 80 · see citing works

Transfer and Metabolism of the Xenoestrogen Zearalenone in Human Perfused Placenta

Warth, B., Preindl, K., Manser, P., Wick, P., Marko, D., & Buerki‐Thurnherr, T. (2019) · Environmental Health Perspectives · doi:10.1289/ehp4860 · Cited by 79 · see citing works

Non-Genomic Effects of Xenoestrogen Mixtures

Viñas, R., Jeng, Y., & Watson, C. S. (2012) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph9082694 · Cited by 77 · see citing works

Levels and profiles of long-chain perfluorinated carboxylic acids in human breast milk and infant formulas in East Asia

Fujii, Y., Yan, J., Harada, K. H., Hitomi, T., Yang, H., Wang, P., & Koizumi, A. (2011) · Chemosphere · doi:10.1016/j.chemosphere.2011.10.035 · Cited by 76 · see citing works

A 3D co-culture microtissue model of the human placenta for nanotoxicity assessment

Muoth, C., Wichser, A., Monopoli, M. P., Correia, M., Ehrlich, N., Loeschner, K., Gallud, A., Kucki, M., Diener, L., Manser, P., et al. (2016) · Nanoscale · doi:10.1039/c6nr06749b · Cited by 76 · see citing works

Perfluoroalkyl Acids (PFAAs) in Serum from 2–4-Month-Old Infants: Influence of Maternal Serum Concentration, Gestational Age, Breast-Feeding, and Contaminated Drinking Water

Gyllenhammar, I., Benskin, J. P., Sandblom, O., Berger, U., Ahrens, L., Lignell, S., Wiberg, K., & Glynn, A. W. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.8b00770 · Cited by 75 · see citing works

A scalable workflow to characterize the human exposome

Hu, X. Y., Walker, D. I., Liang, Y., Smith, M. R., Orr, M. L., Juran, B. D., Ma, C., Uppal, K., Koval, M. H., Martin, G. S., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25840-9 · Cited by 75 · see citing works

Next-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Jamnik, T., Flasch, M., Braun, D., Fareed, Y., Wasinger, D., Seki, D., Berry, D., Berger, A., Wisgrill, L., & Warth, B. (2022) · Nature Communications · doi:10.1038/s41467-022-30204-y · Cited by 74 · see citing works

Robust Microflow LC-MS/MS for Proteome Analysis: 38 000 Runs and Counting

Bian, Y., Bayer, F. P., Chang, Y.-C., Meng, C., Höfer, S., Deng, N., Zheng, R., Boychenko, O., & Küster, B. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c00257 · Cited by 73 · see citing works

Distribution of Silver Nanoparticles to Breast Milk and Their Biological Effects on Breast-Fed Offspring Mice

Morishita, Y., Yoshioka, Y., Takimura, Y., Shimizu, Y., Namba, Y., Nojiri, N., Ishizaka, T., Takao, K., Yamashita, F., Takuma, K., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b01782 · Cited by 72 · see citing works

Mycotoxin exposure biomonitoring in breastfed and non-exclusively breastfed Nigerian children

Ezekiel, C. N., Abia, W. A., Braun, D., Šarkanj, B., Ayeni, K. I., Oyedele, O. A., Michael-Chikezie, E. C., Ezekiel, V. C., Mark, B. N., Ahuchaogu, C. P., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106996 · Cited by 69 · see citing works

Establishment of a confluent monolayer model with human primary trophoblast cells: novel insights into placental glucose transport

Huang, X. B., Lüthi, M., Ontsouka, E. C., Kallol, S., Baumann, M. U., Surbek, D., & Albrecht, C. (2016) · Molecular Human Reproduction · doi:10.1093/molehr/gaw018 · Cited by 64 · see citing works

Role of Microglial Activation and Neuroinflammation in Neurotoxicity of Acrylamide in Vivo and in Vitro

Zong, C., Hasegawa, R., Urushitani, M., Zhang, L., Nagashima, D., Sakurai, T., Ichihara, S., Ohsako, S., & Ichihara, G. (2019) · Archives of Toxicology · doi:10.1007/s00204-019-02471-0 · Cited by 64 · see citing works

Fetal exposure to environmental chemicals; insights from placental perfusion studies

Mathiesen, L., Buerki‐Thurnherr, T., Pastuschek, J., Aengenheister, L., & Knudsen, L. E. (2021) · Placenta · doi:10.1016/j.placenta.2021.01.025 · Cited by 63 · see citing works

Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats

Vyskočilová, E., Szotáková, B., Skálová, L., Bártíková, H., Hlaváčová, J., & Boušová, I. (2013) · BioMed Research International · doi:10.1155/2013/408573 · Cited by 62 · see citing works

Mycotoxins in infant/toddler foods and breakfast cereals in the US retail market

Zhang, K., Flannery, B. M., Oles, C. J., & Adeuya, A. (2018) · Food Additives and Contaminants Part B · doi:10.1080/19393210.2018.1451397 · Cited by 61 · see citing works

Sources of clinically significant neonatal intensive care unit phthalate exposure

Stroustrup, A., Bragg, J. B., Busgang, S. A., Andra, S. S., Curtin, P. C. P., Spear, E. A., Just, A. C., Arora, M., & Gennings, C. (2018) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-018-0069-2 · Cited by 60 · see citing works

A Longitudinal Study of Urinary Phthalate Excretion in 58 Full-Term and 67 Preterm Infants from Birth through 14 Months

Frederiksen, H. W., Kuiri‐Hänninen, T., Main, K. M., Dunkel, L., & Sankilampi, U. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307569 · Cited by 59 · see citing works

Pathogenesis and preventive treatment for animal disease due to locoweed poisoning

Wu, C., Wenlong, W., Xiaoxue, L., Feng, M., Dandan, C., Xiaowen, Y., Shanshan, W., Pengshuai, G., Lu, H., & Baoyu, Z. (2013) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2013.11.013 · Cited by 59 · see citing works

Some chemicals that cause tumours of the urinary tract in rodents

Grosse, Y., LOOMIS, D. P., Guyton, K. Z., Ghissassi, F. E., Bouvard, V., Benbrahim‐Tallaa, L., Mattock, H., & Straíf, K. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(17)30505-3 · Cited by 59 · see citing works

A lab-on-a-chip system with an embedded porous membrane-based impedance biosensor array for nanoparticle risk assessment on placental Bewo trophoblast cells

Schuller, P., Rothbauer, M., Kratz, S. R. A., Höll, G., Taus, P., Schinnerl, M., Genser, J., Bastús, N. G., Moriones, O. H., Puntes, V., et al. (2020) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2020.127946 · Cited by 59 · see citing works

Cytochrome P450 and flavin-containing monooxygenase families: age-dependent differences in expression and functional activity

Zane, N. R., Chen, Y., Wang, M. Z., & Thakker, D. R. (2017) · Pediatric Research · doi:10.1038/pr.2017.226 · Cited by 57 · see citing works

Inspired by the human placenta: a novel 3D bioprinted membrane system to create barrier models

Kreuder, A.-E., Bolaños-Rosales, A., Palmer, C. P., Thomas, A., Geiger, M., Lam, T., Amler, A.-K., Markert, U. R., Lauster, R., & Kloke, L. (2020) · Scientific Reports · doi:10.1038/s41598-020-72559-6 · Cited by 57 · see citing works

Mycotoxin Occurrence, Exposure and Health Implications in Infants and Young Children in Sub-Saharan Africa: A Review

Chilaka, C. A., & Mally, A. (2020) · Foods · doi:10.3390/foods9111585 · Cited by 57 · see citing works

Fate of the teratogenic and carcinogenic ochratoxin A in human perfused placenta

Woo, C. S. J., Partanen, H., Myllynen, P. K., Vähäkangas, K., & El-Nezami, H. S. (2011) · Toxicology Letters · doi:10.1016/j.toxlet.2011.10.013 · Cited by 56 · see citing works

Dioxins/furans and PCBs in Canadian human milk: 2008–2011

Rawn, D. F. K., Sadler, A. R., Casey, V. A., Breton, F., Sun, W., Arbuckle, T. E., & Fraser, W. D. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.03.157 · Cited by 55 · see citing works

Drug–Exposome Interactions: The Next Frontier in Precision Medicine

Pristner, M., & Warth, B. (2020) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2020.09.012 · Cited by 54 · see citing works

The nano cocktail: Ecotoxicological effects of engineered nanoparticles in chemical mixtures

Hartmann, N. B., & Baun, A. (2010) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.39 · Cited by 53 · see citing works

The paradox of caspase 8 in human villous trophoblast fusion

Gauster, M., & Huppertz, B. (2009) · Placenta · doi:10.1016/j.placenta.2009.12.007 · Cited by 52 · see citing works

Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk

Lehmann, G. M., Verner, M.-A., Luukinen, B., Henning, C. C., Assimon, S. A., LaKind, J. S., McLanahan, E. D., Phillips, L. J., Davis, M. H., Powers, C. M., et al. (2014) · Critical Reviews in Toxicology · doi:10.3109/10408444.2014.926306 · Cited by 52 · see citing works

Comparison of urinary aflatoxin M1 and aflatoxin albumin adducts as biomarkers for assessing aflatoxin exposure in Tanzanian children

Chen, G., Gong, Y. Y., Kimanya, M. E., Shirima, C. P., & Routledge, M. N. (2017) · Biomarkers · doi:10.1080/1354750x.2017.1285960 · Cited by 52 · see citing works

Developmental toxicity, oxidative stress, and related gene expression induced by dioxin-like PCB 126 in zebrafish (Danio rerio)

Liu, H., Nie, F., Lin, H., Ma, Y., Ju, X., Chen, J., & Gooneratne, R. (2014) · Environmental Toxicology · doi:10.1002/tox.22044 · Cited by 51 · see citing works

Natural contaminants in infant food: The case of regulated and emerging mycotoxins

Braun, D., Eiser, M., Puntscher, H., Marko, D., & Warth, B. (2020) · Food Control · doi:10.1016/j.foodcont.2020.107676 · Cited by 50 · see citing works

Paediatric Medicines in Europe: The Paediatric Regulation—Is It Time for Reform?

Toma, M., Felisi, M., Bonifazi, D., Bonifazi, F., Giannuzzi, V., Reggiardo, G., de Wildt, S. N., & Ceci, A. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.593281 · Cited by 50 · see citing works

Occurrence of Melamine and Its Derivatives in Breast Milk from the United States and Its Implications for Exposure in Infants

Zhu, H., & Kannan, K. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b02040 · Cited by 49 · see citing works

Prenatal Exposure to Nonpersistent Chemical Mixtures and Fetal Growth: A Population-Based Study

van den Dries, M. A., Keil, A. P., Tiemeier, H. W., Pronk, A., Spaan, S., Santos, S., Asimakopoulos, A. G., Kannan, K., Gaillard, R., Guxens, M., et al. (2021) · Environmental Health Perspectives · doi:10.1289/ehp9178 · Cited by 49 · see citing works

In vitro simulation of placental transport: Part I. Biological model of the placental barrier

Levkovitz, R., Zaretsky, U., Gordon, Z., Jaffa, A. J., & Elad, D. (2013) · Placenta · doi:10.1016/j.placenta.2013.03.014 · Cited by 47 · see citing works

P-Glycoprotein-Mediated Drug Interactions in Pregnancy and Changes in the Risk of Congenital Anomalies: A Case-Reference Study

Daud, A. N. A., Bergman, J. E. H., Bakker, M. K., Wang, H., Kerstjens-Frederikse, W. S., de Walle, H. E. K., Groen, H., Bos, J. H. J., Hak, E., & Wilffert, B. (2015) · Drug Safety · doi:10.1007/s40264-015-0299-3 · Cited by 46 · see citing works

Microfluidic Co‐Culture Platform to Recapitulate the Maternal–Placental–Embryonic Axis

Boos, J. A., Misun, P. M., Brunoldi, G., Furer, L. A., Aengenheister, L., Modena, M. M., Rousset, N., Buerki‐Thurnherr, T., & Hierlemann, A. R. (2021) · Advanced Biology · doi:10.1002/adbi.202100609 · Cited by 46 · see citing works

Dose- and Time-Dependent Epigenetic Changes in the Livers of Fisher 344 Rats Exposed to Furan

de Conti, A., Kobets, T., Escudero‐Lourdes, C., Montgomery, B. A., Tryndyak, V., Beland, F. A., Doerge, D. R., & Pogribny, I. P. (2014) · Toxicological Sciences · doi:10.1093/toxsci/kfu044 · Cited by 43 · see citing works

Phthalate-associated hypertension in premature infants: a prospective mechanistic cohort study

Jenkins, R., Tackitt, S., Gievers, L., Iragorri, S., Sage, K., Cornwall, T., O’Riordan, D., Merchant, J., & Rozansky, D. (2019) · Pediatric Nephrology · doi:10.1007/s00467-019-04244-4 · Cited by 42 · see citing works

Transplacental transfer of organochlorine pesticides: Concentration ratio and chiral properties

Yin, S., Zhang, J., Guo, F., Zhao, L., Poma, G., Covaci, A., & Liu, W. (2019) · Environment International · doi:10.1016/j.envint.2019.104939 · Cited by 42 · see citing works

Exploring associations between prenatal exposure to multiple endocrine disruptors and birth weight with exposure continuum mapping

Pearce, J. L., Neelon, B., Bloom, M. S., Buckley, J. P., Ananth, C. V., Perera, F. P., Vena, J. E., & Hunt, K. J. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111386 · Cited by 42 · see citing works

Exposure of nursing mothers to polycyclic aromatic hydrocarbons: Levels of un-metabolized and metabolized compounds in breast milk, major sources of exposure and infants’ health risks

Oliveira, M., Duarte, S. C., Delerue-Matos, C. M., Pena, A., & Morais, S. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.115243 · Cited by 41 · see citing works

Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment

Buratti, F. M., Darney, K., Vichi, S., Turco, L., Consiglio, E. D., Lautz, L. S., Béchaux, C., Dorne, J. L. C. M., & Testai, E. (2020) · Toxicology Letters · doi:10.1016/j.toxlet.2020.11.007 · Cited by 40 · see citing works

Placenta and trophoblast : methods and protocols

Soares, M. J., & Hunt, J. S. (2006) · Cited by 39 · see citing works

Unravelling the chemical exposome in cohort studies: routes explored and steps to become comprehensive

Hühn, S., Escher, B. I., Krauss, M. K. V., Scholz, S., Hackermüller, J., & Altenburger, R. (2021) · Environmental Sciences Europe · doi:10.1186/s12302-020-00444-0 · Cited by 39 · see citing works

Comparison of polycyclic aromatic hydrocarbon metabolite concentrations in urine of mothers and their newborns

Urbancová, K., Dvořáková, D., Gramblička, T., Šrám, R. J., Hajšlová, J., & Pulkrábová, J. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138116 · Cited by 37 · see citing works

Tooth biomarkers to characterize the temporal dynamics of the fetal and early-life exposome

Yu, M., Tu, P., Dolios, G., Dassanayake, P. S., Volk, H. E., Newschaffer, C. J., Fallin, M. D., Croen, L., Lyall, K., Schmidt, R. J., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106849 · Cited by 36 · see citing works

Developmental Expression of the Cytosolic Sulfotransferases in Human Liver

Dubaisi, S., Caruso, J. A., Gaedigk, R., Vyhlidal, C. A., Smith, P. C., Hines, R. N., Kocarek, T. A., & Runge‐Morris, M. (2019) · Drug Metabolism and Disposition · doi:10.1124/dmd.119.086363 · Cited by 35 · see citing works

Dose Addition in the Induction of Craniofacial Malformations in Zebrafish Embryos Exposed to a Complex Mixture of Food-Relevant Chemicals with Dissimilar Modes of Action

van der Ven, L. T. M., Ommeren, P. V., Zwart, E., Gremmer, E. R., Hodemaekers, H. M., Heusinkveld, H. J., van Klaveren, J. D., & Rorije, E. (2022) · Environmental Health Perspectives · doi:10.1289/ehp9888 · Cited by 33 · see citing works

Assessment of dually labelled PEGylated liposomes transplacental passage and placental penetration using a combination of two ex-vivo human models: the dually perfused placenta and the suspended villous explants

Valéro, L., Alhareth, K., Gil, S., Simasotchi, C., Roques, C., Scherman, D., Mignet, N., Fournier, T., & Andrieux, K. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.07.076 · Cited by 32 · see citing works

Early life exposure to phthalates in the Canadian Healthy Infant Longitudinal Development (CHILD) study: a multi-city birth cohort

Navaranjan, G., Takaro, T. K., Wheeler, A. J., Diamond, M. L., Shu, H., Azad, M. B., Becker, A. B., Dai, R., Harris, S. A., Lefebvre, D. L., et al. (2019) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-019-0182-x · Cited by 31 · see citing works

Infant and young child feeding

OECD, & World Health Organization (2022) · Health at a glance. Asia/Pacific · doi:10.1787/cf999c59-en · Cited by 31 · see citing works

Hidden Toxicity in Neonatal Intensive Care Units: Phthalate Exposure in Very Low Birth Weight Infants

Demırel, A., Çoban, A. Ç., Yıldırım, Ş., Doğan, C., Sancı, R., & İnce, Z. (2016) · Journal of Clinical Research in Pediatric Endocrinology · doi:10.4274/jcrpe.3027 · Cited by 30 · see citing works

Relationship between serum dioxin-like polychlorinated biphenyls and post-testicular maturation in human sperm

Paul, R., Moltó, J., Ortuño, N., Romero, A., Bezos, C., Aizpurúa, J., & Gómez‐Torres, M. J. (2017) · Reproductive Toxicology · doi:10.1016/j.reprotox.2017.07.004 · Cited by 30 · see citing works

Maternal exposure to endocrine disruptors and placental transmission: a pilot study

Caserta, D., Pegoraro, S., Mallozzi, M., Benedetto, L. D., Colicino, E., Lionetto, L., & Simmaco, M. (2018) · Gynecological Endocrinology · doi:10.1080/09513590.2018.1473362 · Cited by 30 · see citing works

Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish

Brun, N. R., Panlilio, J. M., Zhang, K., Zhao, Y., Ivashkin, E. G., Stegeman, J. J., & Goldstone, J. V. (2021) · Communications Biology · doi:10.1038/s42003-021-02626-9 · Cited by 30 · see citing works

The road (not) taken – Placental transfer and interspecies differences

Schmidt, A., Schmidt, A., & Markert, U. R. (2021) · Placenta · doi:10.1016/j.placenta.2021.09.011 · Cited by 30 · see citing works

Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo

Leonetti, C. P., Butt, C. M., & Stapleton, H. M. (2017) · Chemosphere · doi:10.1016/j.chemosphere.2017.12.172 · Cited by 29 · see citing works

Age-associated changes in GSH S-transferase gene/proteins in livers of rats

Xu, S., Hou, D.-S., Liu, J., & Ji, L. (2018) · Redox Report · doi:10.1080/13510002.2018.1546985 · Cited by 29 · see citing works

Analytical strategies for chemical exposomics: exploring limits and feasibility

Vitale, C. M., Price, E. J., Miller, G. W., David, A., Antignac, J., Barouki, R., & Klánová, J. (2021) · Exposome · doi:10.1093/exposome/osab003 · Cited by 28 · see citing works

Dendritic polyglycerol nanoparticles show charge dependent bio-distribution in early human placental explants and reduce hCG secretion

Juch, H., Nikitina, L., Reimann, S., Gauster, M., Dohr, G., Obermayer-Pietsch, B. M., Hoch, D., Kornmueller, K., & Haag, R. (2018) · Nanotoxicology · doi:10.1080/17435390.2018.1425496 · Cited by 26 · see citing works

Human biomonitoring in Australian children: Brominated flame retardants decrease from 2006 to 2015

Drage, D. S., Harden, F. A., Jeffery, T., Mueller, J. F., Hobson, P., & Toms, L.-M. L. (2018) · Environment International · doi:10.1016/j.envint.2018.11.044 · Cited by 24 · see citing works

FAIRifying the exposome journal: Templates for chemical structures and transformations

Schymanski, E., & Bolton, E. (2021) · Exposome · doi:10.1093/exposome/osab006 · Cited by 23 · see citing works

Derivation of exposure factors for infant lactational exposure to persistent organic pollutants (POPs)

Haddad, S., Ayotte, P., & Verner, M.-A. (2014) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2014.12.003 · Cited by 20 · see citing works

Urinary metabolites of phthalates and di-iso-nonyl cyclohexane-1,2-dicarboxylate (DINCH)–Czech mothers' and newborns' exposure biomarkers

Urbancová, K., Lanková, D., Šrám, R. J., Hajšlová, J., & Pulkrábová, J. (2019) · Environmental Research · doi:10.1016/j.envres.2019.03.067 · Cited by 20 · see citing works

Systematic Investigation of LC Miniaturization to Increase Sensitivity in Wide-Target LC-MS-Based Trace Bioanalysis of Small Molecules

Fitz, V., Abiead, Y. E., Berger, D., & Koellensperger, G. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.857505 · Cited by 20 · see citing works

Transfer of Deoxynivalenol (DON) through Placenta, Colostrum and Milk from Sows to Their Offspring during Late Gestation and Lactation

Sayyari, A., Uhlig, S., Fæste, C. K., Framstad, T., & Sivertsen, T. (2018) · Toxins · doi:10.3390/toxins10120517 · Cited by 19 · see citing works

Oxidative and nitrosative stress in the neurotoxicity of polybrominated diphenyl ether-153: possible mechanism and potential targeted intervention

Zhang, H., Yang, X., Li, X., Cheng, Y., Zhang, H., Chang, L., Sun, M., Zhang, Z., Wang, Z., Niu, Q. L., et al. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.124602 · Cited by 19 · see citing works

Frequency and levels of aflatoxin M1 in urine of children in Bogota, Colombia

Sánchez, E., & Díaz, G. J. (2019) · Mycotoxin Research · doi:10.1007/s12550-019-00355-x · Cited by 16 · see citing works

Prenatal exposure to pyrrolizidine alkaloids induced hepatotoxicity and pulmonary injury in fetal rats

Guo, Y., Xiao, D., Yang, X., Zheng, J., Hu, S., Wu, P., Li, X., Kou, H., & Wang, H. (2019) · Reproductive Toxicology · doi:10.1016/j.reprotox.2019.02.006 · Cited by 15 · see citing works

An improved in vitro model simulating the feto-maternal interface to study developmental effects of potentially toxic compounds: The example of titanium dioxide nanoparticles

Lacconi, V., Massimiani, M., Paglione, L., Messina, A., Battistini, B., Filippis, P. D., Magrini, A., Pietroiusti, A., & Campagnolo, L. (2022) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2022.116056 · Cited by 11 · see citing works

Brain structural and functional outcomes in the offspring of women experiencing psychological distress during pregnancy

Wu, Y., De Asis-Cruz, J., & Limperopoulos, C. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02449-0 · Cited by 124 · see citing works

A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

Tahir, I., & Alkheraije, K. A. (2023) · Frontiers in Veterinary Science · doi:10.3389/fvets.2023.1149720 · Cited by 96 · see citing works

Exposure to PFOA, PFOS, and PFHxS induces Alzheimer's disease-like neuropathology in cerebral organoids

Lu, S., Zhu, X., Zeng, P., Hu, L., Huang, Y., Guo, X., Chen, Q., Wang, Y., Lai, L., Xue, A., et al. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.125098 · Cited by 61 · see citing works

Studying the Impact of Persistent Organic Pollutants Exposure on Human Health by Proteomic Analysis: A Systematic Review

Guillotin, S., & Delcourt, N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232214271 · Cited by 52 · see citing works

Sample preparation strategies for mass spectrometry analysis in human exposome research: Current status and future perspectives

Gu, Y., Peach, J. T., & Warth, B. (2023) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2023.117151 · Cited by 40 · see citing works

The potential mediating role of the gut microbiome and metabolites in the association between PFAS and kidney function in young adults: A proof-of-concept study

Hampson, H. E., Li, S., Walker, D. I., Wang, H., Jia, Q., Rock, S., Costello, E. J., Bjornstad, P., Pyle, L. L., Nelson, J. W., et al. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.176519 · Cited by 31 · see citing works

Nervonic acid improves liver inflammation in a mouse model of Parkinson's disease by inhibiting proinflammatory signaling pathways and regulating metabolic pathways

Wang, X., Liang, T., Mao, Y. Q., Li, Z., Li, X., Zhu, X., Cao, F., & Zhang, J. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154911 · Cited by 30 · see citing works

Biomonitoring of Dietary Mycotoxin Exposure and Associated Impact on the Gut Microbiome in Nigerian Infants

Ayeni, K. I., Seki, D., Pjevac, P., Hausmann, B., Krausová, M., Braun, D., Wisgrill, L., Berry, D., Warth, B., & Ezekiel, C. N. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.3c07786 · Cited by 23 · see citing works

High-Throughput Solid Phase Extraction for Targeted and Nontargeted Exposomics

Gu, Y., Feuerstein, M. L., & Warth, B. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.4c06177 · Cited by 23 · see citing works

The exposome approach to study children's health

Handakas, E., Robinson, O., & Laine, J. E. (2023) · Current Opinion in Environmental Science & Health · doi:10.1016/j.coesh.2023.100455 · Cited by 21 · see citing works

Multi-omics and gut microbiome: Unveiling the pathogenic mechanisms of early-life pesticide exposure

Yue, Y., Sun, X., Tian, S., Yan, S., Sun, W., Miao, J., Huang, S., Diao, J., Zhou, Z., & Zhu, W. (2024) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2024.105770 · Cited by 17 · see citing works

The Austrian children's biomonitoring survey 2020 Part B: Mycotoxins, phytotoxins, phytoestrogens and food processing contaminants

Ayeni, K. I., Jamnik, T., Fareed, Y., Flasch, M., Braun, D., Uhl, M., Hartmann, C., & Warth, B. (2023) · Food and Chemical Toxicology · doi:10.1016/j.fct.2023.114173 · Cited by 16 · see citing works

Dried blood spots analysis for targeted and non-targeted exposomics

Hernandes, V. V., Zeyda, M., Wisgrill, L., & Warth, B. (2025) · Environment International · doi:10.1016/j.envint.2025.109814 · Cited by 15 · see citing works

A Critical Review on the Opportunity to Use Placenta and Innovative Biomonitoring Methods to Characterize the Prenatal Chemical Exposome

Contini, T., Béranger, R., Multigner, L., Klánová, J., Price, E. J., & David, A. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.3c04845 · Cited by 15 · see citing works

Rapid Screening of Chemicals with Placental Transfer Risk Using Interpretable Machine Learning

Chen, X., Yao, J., Ma, Y., Fang, Y., Wang, W., Deng, X., Tan, L., Fan, Y., & Fang, M. (2024) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.4c00413 · Cited by 13 · see citing works

Metabolomics-enabled biomarker discovery in breast cancer research

Füreder, J., Schernhammer, E. S., Eliassen, A. H., Sieri, S., & Warth, B. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.04.008 · Cited by 12 · see citing works

Exposures to Contemporary and Emerging Chemicals among Children Aged 2 to 4 Years in the United States Environmental Influences on the Child Health Outcome (ECHO) Cohort

Oh, J., Buckley, J. P., Kannan, K., Pellizzari, E. D., Miller, R., Bastain, T. M., Dunlop, A. L., Douglas, C. E., Gilliland, F. D., Herbstman, J. B., et al. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.4c13605 · Cited by 12 · see citing works

Insights into the early-life chemical exposome of Nigerian infants and potential correlations with the developing gut microbiome

Oesterle, I., Ayeni, K. I., Ezekiel, C. N., Berry, D., Rompel, A., & Warth, B. (2024) · Environment International · doi:10.1016/j.envint.2024.108766 · Cited by 12 · see citing works

High lead contamination in Mother's breastmilk in Bihar (India): Health risk assessment of the feeding children

Agarwal, R., Kumar, A. J., Pandey, T., Chayal, N. K., Verma, K. S., Kumar, D., Kumar, K., Aryal, S., Singh, P. K., Ali, M., et al. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.143064 · Cited by 11 · see citing works

Maternal exposure to phthalates and nanoplastics, isolated or combined: Impacts on placental structure, development, and antioxidant defense as a trigger for maternal-fetal adversities

Magosso, N. S. S., de Souza, P. V., Moreira, M. F., Rocha, V. A., Fioretto, M. N., Pinha, V. C., Maia, G. A., Maria, V. L. R. S., Barata, L. A., Frigoli, G. F., et al. (2025) · Reproductive Toxicology · doi:10.1016/j.reprotox.2025.108930 · Cited by 11 · see citing works

Urinary biomarker-based seasonal mycotoxin exposure assessment in rural resident populations of North-central Nigeria

Ezekiel, C. N., Ayeni, K. I., Šarkanj, B., Sulyok, M., Akinyemi, M. O., Ogara, I. M., Turner, P. C., Warth, B., & Krska, R. (2025) · Environment International · doi:10.1016/j.envint.2025.109713 · Cited by 9 · see citing works

Advances in the Use of Residual Newborn Dried Blood Spots Within Environmental Epidemiology

Doung, R. A., Garrick, J. M., & Marsillach, J. (2023) · Current Epidemiology Reports · doi:10.1007/s40471-023-00338-8 · Cited by 7 · see citing works

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Chen, Z., Sun, X., Liu, Y., Zhao, X., Guo, Y., & Wang, H. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116980 · Cited by 7 · see citing works

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Moyer, H. L., Kim, S., Lam, B. P., Richardson, L., Tsai, H.-H. D., Ford, L. C., Lin, H.-C. C., Chiu, W. A., Menon, R., Han, A., et al. (2025) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2025.111782 · Cited by 6 · see citing works

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Gonzalez, B., Bartels, K., & Talyn, B. (2025) · Food and Chemical Toxicology · doi:10.1016/j.fct.2025.115621 · Cited by 6 · see citing works

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Jobst, M., Guerreiro, I., Payros, D., Oswald, I. P., Fernandes, A. S., Warth, B., & Favero, G. D. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118649 · Cited by 6 · see citing works

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Scher, M. S., Agarwal, S., & Venkatesen, C. (2024) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2024.101521 · Cited by 6 · see citing works

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Yang, S., Im, H., Kim, Y., Kim, H., Kim, J., Yeom, J., Yoo, H. J., Kim, M. J., Seong, H. J., Oh, H. Y., et al. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118533 · Cited by 5 · see citing works

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Ng, S., Chen, L., Chen, Z.-Y., Chen, M., Chu, A. H. Y., Godfrey, K. M., Tan, K. H., Gluckman, P. D., Eriksson, J. G., Yap, F. K. P., et al. (2025) · Environmental Health · doi:10.1186/s12940-025-01202-6 · Cited by 5 · see citing works

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Paulsen, M. M., Haug, L. S., Sakhi, A. K., Thomsen, C., & Brantsæter, A. L. (2025) · Environmental Research · doi:10.1016/j.envres.2025.121871 · Cited by 5 · see citing works

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Hossain, M. Z., Feuerstein, M. L., & Warth, B. (2025) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70105 · Cited by 5 · see citing works

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Raghavan, R., & Ahamad, S. (2025) · IGI Global eBooks · doi:10.4018/979-8-3373-2165-3.ch001 · Cited by 5 · see citing works

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Nair, S. R., Nihad, M., Sudheer Shenoy, P., Gupta, S., & Bose, B. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.101954 · Cited by 4 · see citing works

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Chen, W.-R., Huang, Y., Zhou, W., Yang, J., Ren, T., Zhang, L., Zhu, T., Shan, X., Du, Y., Zhou, G., et al. (2026) · Environment International · doi:10.1016/j.envint.2026.110233 · Cited by 3 · see citing works

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Feuerstein, M. L., Hossain, M. Z., Kyei, N. N. A., Gabrysch, S., & Warth, B. (2025) · Environment International · doi:10.1016/j.envint.2025.110029 · Cited by 3 · see citing works

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Zhang, J., Jiang, W. J., Tao, F., Ding, G., Li, F., Tian, Y., & Tao, S. (2025) · Eco-Environment & Health · doi:10.1016/j.eehl.2025.01.001 · Cited by 3 · see citing works

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Ambrož, A., Kléma, J., Rössnerová, A., Milcová, A., Pastorková, A., Pulkrábová, J., Parizek, O., Gomersall, V., Gramblička, T., Zelenka, J., et al. (2025) · Frontiers in Toxicology · doi:10.3389/ftox.2025.1572486 · Cited by 3 · see citing works

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Goutelle, A., Viseur, J., Boudjeltia, K. Z., Nuyens, V., Cavatorta, E., Antwerpen, P. V., & Marechal, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e32350 · Cited by 3 · see citing works

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Fattahi, P., Younesi, M., Lee, W. D., Whang, K., Kim, S., Kang, T., Aleksunes, L. M., & Huh, D. (2026) · Nature Biomedical Engineering · doi:10.1038/s41551-026-01801-9 · Cited by 3 · see citing works

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Gheisary, Z., & Thompson, J. A. (2025) · Pediatric Research · doi:10.1038/s41390-025-04609-6 · Cited by 2 · see citing works

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Siskos, A., Keun, H. C., Warth, B., Kelly, R. S., & Maître, L. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1188673 · Cited by 2 · see citing works

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Andonotopo, W., Bachnas, M. A., Dewantiningrum, J., Pramono, B. A., Bernolian, N., Yeni, C. M., Wiradnyana, A. A. G. P., Sanjaya, I. N. H., Akbar, M. I. A., Darmawan, E., et al. (2025) · Journal of Perinatal Medicine · doi:10.1515/jpm-2025-0231 · Cited by 1 · see citing works

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Ngoungoure, L. V. N., Abia, W. A., Owona, B. A., Foupouapouognigni, Y., Elombo, F. K., Njitoyap, H. P. N., Ntungwe, E. N., Njayou, F. N., Tchana, A. N., & Moundipa, P. F. (2025) · Developmental Neurobiology · doi:10.1002/dneu.23000 · Cited by 2 · see citing works

The Neural Exposome and Environmental Neuroscience

Scher, M. S., & Wing, S. E. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-10944-7.00033-0

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Elamrani, F. E., Loqman, S., & Belbachir, A. (2025) · IGI Global eBooks · doi:10.4018/979-8-3373-2165-3.ch006

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Hanson, M. A., Bustreo, F., Renzo, G. C. D., Gilmore, A., Kihara, A., Maani, N., Malamitsi‐Puchner, A., Rowland, D., & Modi, N. (2025) · npj Women s Health · doi:10.1038/s44294-025-00090-y

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Li, J., Chen, S., Wu, P., & Li, Y. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5467259

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Román, A. S., Musatadi, M., Ayala-Cabrera, J. F., González-Gaya, B., Irizar, A., Abilleira, E., & Etxebarría, N. (2026) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2026.114855

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Linguo, P., Zhang, Y., Zhang, W. T., Wei, W., Dazeng, X., & Wenyu, J. (2026) · Toxicology Research · doi:10.1093/toxres/tfag053

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Braeuer, S., Feuerstein, M. L., Buerki‐Thurnherr, T., Warth, B., & Koellensperger, G. (2026) · Talanta · doi:10.1016/j.talanta.2026.130499

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Nishanthini, B., Yazhini, A., Kumar, P., Saravanan, P., Rajeshkannan, R., Rajasimman, M., & Kumar, S. V. (2026) · Environmental Research · doi:10.1016/j.envres.2026.125878

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Wei, H., 温素威, Tan, B., Qiu, X., Li, P., Li, J., Xia, T., Wang, A., Gao, H., & Zhang, S. (2026) · Environmental Pollution · doi:10.1016/j.envpol.2026.129440

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Orešič, M., McGlinchey, A. J., Wheelock, C. E., & Hyötyläinen, T. (2020) · Metabolites · doi:10.3390/metabo10110454 · Cited by 49 · see citing works

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