Stem and Progenitor Cells: Origins, Phenotypes, Lineage Commitments, and Transdifferentiations

Multilineage potential of adult human mesenchymal stem cells

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Bonnet, D. A., & Dick, J. E. (1997) · Nature Medicine · doi:10.1038/nm0797-730 · Cited by 7,197

Neurogenesis in the adult human hippocampus

Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369

Bone marrow cells regenerate infarcted myocardium

Orlic, D., Kajstura, J., Chimenti, S., Jakoniuk, I., Anderson, S. M., Li, B., Pickel, J. M., McKay, R. D. G., Nadal‐Ginard, B., Bodine, D. M., et al. (2001) · Nature · doi:10.1038/35070587 · Cited by 5,149

Mammalian neural stem cells.

Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 4,786

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

Reynolds, B. A., & Weiss, S. (1992) · Science · doi:10.1126/science.1553558 · Cited by 4,482

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells1

Till, J. E., & McCulloch, E. A. (2010) · Radiation Research · doi:10.1667/rrxx28.1 · Cited by 4,036

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

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More hippocampal neurons in adult mice living in an enriched environment

Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,586

Purification and Characterization of Mouse Hematopoietic Stem Cells

Spangrude, G. J., Heimfeld, S., & Weissman, I. L. (1988) · Science · doi:10.1126/science.2898810 · Cited by 2,908

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo.

Goodell, M. A., Brose, K., Paradis, G. A., Conner, A. N., & Mulligan, R. C. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.4.1797 · Cited by 2,902

Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors

Ferrari, G., Cusella, G., Angelis, D., Coletta, M., Paolucci, E., Stornaiuolo, A., Cossu, G., & Mavilio, F. (1998) · Science · doi:10.1126/science.279.5356.1528 · Cited by 2,721

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Akashi, K., Traver, D., Miyamoto, T., & Weissman, I. L. (2000) · Nature · doi:10.1038/35004599 · Cited by 2,617

Bone Marrow as a Potential Source of Hepatic Oval Cells

Petersen, B. E., Bowen, W. C., Patrene, K. D., Mars, W. M., Sullivan, A. K., Murase, N., Boggs, S. S., Greenberger, J. S., & Goff, J. P. (1999) · Science · doi:10.1126/science.284.5417.1168 · Cited by 2,377

Long-Distance Neuronal Migration in the Adult Mammalian Brain

Lois, C., & Álvarez-Buylla, A. (1994) · Science · doi:10.1126/science.8178174 · Cited by 2,331

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo

Lagasse, E., Connors, H., Al-Dhalimy, M., Reitsma, M., Dohse, M., Osborne, L., Wang, X., Finegold, M., Weissman, I. L., & Grompe, M. (2000) · Nature Medicine · doi:10.1038/81326 · Cited by 2,314

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

Kondo, M., Weissman, I. L., & Akashi, K. (1997) · Cell · doi:10.1016/s0092-8674(00)80453-5 · Cited by 2,253

Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

Johansson, C. B., Momma, S., Clarke, D. L., Risling, M., Lendahl, U., & Frisén, J. (1999) · Cell · doi:10.1016/s0092-8674(00)80956-3 · Cited by 1,875

Direct isolation of human central nervous system stem cells

Uchida, N., Buck, D. W., He, D., Reitsma, M. J., Masek, M., Phan, T. V., Tsukamoto, A. S., Gage, F. H., & Weissman, I. L. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.26.14720 · Cited by 1,829

Stem Cells

Weissman, I. L. (2000) · Cell · doi:10.1016/s0092-8674(00)81692-x · Cited by 1,827

Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow

Mezey, É., Chandross, K. J., Harta, G., Maki, R. A., & McKercher, S. R. (2000) · Science · doi:10.1126/science.290.5497.1779 · Cited by 1,814

Dystrophin expression in the mdx mouse restored by stem cell transplantation

Gussoni, E., Soneoka, Y., Strickland, C. D., Buzney, E. A., Khan, M. K., Flint, A., Kunkel, L. M., & Mulligan, R. C. (1999) · Nature · doi:10.1038/43919 · Cited by 1,800

From Marrow to Brain: Expression of Neuronal Phenotypes in Adult Mice

Brazelton, T. R., Rossi, F. M. V., Keshet, G. I., & Blau, H. M. (2000) · Science · doi:10.1126/science.290.5497.1775 · Cited by 1,666

Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains

Kopen, G. C., Prockop, D. J., & Phinney, D. G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.19.10711 · Cited by 1,643

Cytological Demonstration of the Clonal Nature of Spleen Colonies Derived from Transplanted Mouse Marrow Cells

Becker, A., Mcculloch, E., & Till, J. (1963) · Nature · doi:10.1038/197452a0 · Cited by 1,570

Turning Brain into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells in Vivo

Bjornson, C. R. R., Rietze, R. L., Reynolds, B. A., Magli, M. C., & Vescovi, A. L. (1999) · Science · doi:10.1126/science.283.5401.534 · Cited by 1,412

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

Morshead, C. M., Reynolds, B. A., Craig, C. G., McBurney, M. W., Staines, W. A., Morassutti, D., Weiss, S., & van der Kooy, D. (1994) · Neuron · doi:10.1016/0896-6273(94)90046-9 · Cited by 1,403

Clonal and Population Analyses Demonstrate That an EGF-Responsive Mammalian Embryonic CNS Precursor Is a Stem Cell

Reynolds, B. A., & Weiss, S. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0090 · Cited by 1,368

Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.

Lois, C., & Álvarez-Buylla, A. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.5.2074 · Cited by 1,339

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

Kuhn, H. G., Winkler, J., Kempermann, G., Thal, L. J., & Gage, F. H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-15-05820.1997 · Cited by 1,214

Liver from bone marrow in humans

Theise, N. D., Nimmakayalu, M., Gardner, R., Illei, P. B., Morgan, G., Teperman, L., Henegariu, O., & Krause, D. S. (2000) · Hepatology · doi:10.1053/jhep.2000.9124 · Cited by 1,210

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.Preprint

Johe, K. K., Hazel, T. G., Müller, T. H., Dugich‐Djordjevic, M. M., & McKay, R. D. G. (1996) · Genes & Development · doi:10.1101/gad.10.24.3129 · Cited by 1,154

The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

Morrison, S. J., & Weissman, I. L. (1994) · Immunity · doi:10.1016/1074-7613(94)90037-x · Cited by 1,116

The Adult Rat Hippocampus Contains Primordial Neural Stem Cells

Palmer, T. D., TAKAHASHI, J. C., & Gage, F. H. (1997) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1996.0595 · Cited by 1,103

Isolation of a candidate human hematopoietic stem-cell population.

Baum, C. M., Weissman, I. L., Tsukamoto, A. S., Buckle, A., & Péault, B. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.7.2804 · Cited by 1,084

Generalized Potential of Adult Neural Stem Cells

Clarke, D. L., Johansson, C. B., Wilbertz, J. H., Veress, B., Nilsson, E. D., Karlström, H., Lendahl, U., & Frisén, J. (2000) · Science · doi:10.1126/science.288.5471.1660 · Cited by 1,057

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

Gritti, A., Parati, E. A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., Morassutti, D. J., Roisen, F. J., Nickel, D. D., et al. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-03-01091.1996 · Cited by 1,029

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

Metcalf, D. (1989) · Nature · doi:10.1038/339027a0 · Cited by 1,023

Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain.

Goldman, S. A., & Nottebohm, F. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.8.2390 · Cited by 995

Embryonic Stem Cell-Derived Glial Precursors: A Source of Myelinating Transplants

Brüstle, O., Jones, K. N., Learish, R. D., Karram, K., Choudhary, K., Wiestler, O. D., Duncan, I. D., & McKay, R. D. G. (1999) · Science · doi:10.1126/science.285.5428.754 · Cited by 976

Are New Neurons Formed in the Brains of Adult Mammals?

Altman, J. (1962) · Science · doi:10.1126/science.135.3509.1127 · Cited by 975

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation

Theise, N. D., Badve, S., Saxena, R., Henegariu, O., Sell, S., Crawford, J. M., & Krause, D. S. (2000) · Hepatology · doi:10.1002/hep.510310135 · Cited by 965

Hematopoietic potential of stem cells isolated from murine skeletal muscle

Jackson, K. A., Mi, T., & Goodell, M. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.25.14482 · Cited by 953

Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.

Pereira, R. F., Halford, K. W., O’Hara, M. D., Leeper, D. B., Sokolov, B. P., Pollard, M. D., Bagasra, O., & Prockop, D. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.4857 · Cited by 925

Autoradiographic and histological studies of postnatal neurogenesis. I. A longitudinal investigation of the kinetics, migration and transformation of cells incoorporating tritiated thymidine in neonate rats, with special reference to postnatal neurogenesis in some brain regions

Altman, J., & Das, G. D. (1966) · The Journal of Comparative Neurology · doi:10.1002/cne.901260302 · Cited by 921

Oligodendrocyte Precursor Cells Reprogrammed to Become Multipotential CNS Stem Cells

Kondo, T., & RAFF, M. C. (2000) · Science · doi:10.1126/science.289.5485.1754 · Cited by 880

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

Cheshier, S. H., Morrison, S. J., Liao, X., & Weissman, I. L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.6.3120 · Cited by 858

Translating Stem and Progenitor Cell Biology to the Clinic: Barriers and Opportunities

Weissman, I. L. (2000) · Science · doi:10.1126/science.287.5457.1442 · Cited by 852

Isolation of a stem cell for neurons and glia from the mammalian neural crest

Stemple, D. L., & Anderson, D. J. (1992) · Cell · doi:10.1016/0092-8674(92)90393-q · Cited by 800

Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members

Shah, N. M., Groves, A. K., & Anderson, D. J. (1996) · Cell · doi:10.1016/s0092-8674(00)81112-5 · Cited by 779

Engraftable human neural stem cells respond to development cues, replace neurons, and express foreign genes

Flax, J. D., Aurora, S., Yang, C., Simonin, C., Wills, A. M., Billinghurst, L. L., Jendoubi, M., Sidman, R. L., Wolfe, J. H. N., Kim, S. U., et al. (1998) · Nature Biotechnology · doi:10.1038/3473 · Cited by 766

Prospective Identification, Isolation by Flow Cytometry, and In Vivo Self-Renewal of Multipotent Mammalian Neural Crest Stem Cells

Morrison, S. J., White, P. M., Zock, C., & Anderson, D. J. (1999) · Cell · doi:10.1016/s0092-8674(00)80583-8 · Cited by 749

Transient Notch Activation Initiates an Irreversible Switch from Neurogenesis to Gliogenesis by Neural Crest Stem Cells

Morrison, S. J., Perez, S. E., Zhou, Q., Verdi, J. M., Hicks, C. D., Weinmaster, G., & Anderson, D. J. (2000) · Cell · doi:10.1016/s0092-8674(00)80860-0 · Cited by 721

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.

Ikuta, K., & Weissman, I. L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.4.1502 · Cited by 637

A self-renewing multipotential stem cell in embryonic rat cerebral cortex

Davis, A. A., & Temple, S. (1994) · Nature · doi:10.1038/372263a0 · Cited by 577

Site-Specific Migration and Neuronal Differentiation of Human Neural Progenitor Cells after Transplantation in the Adult Rat Brain

Fricker, R. A., Carpenter, M. K., Winkler, C., Greco, C., Gates, M. A., & Björklund, A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-14-05990.1999 · Cited by 558

De novo generation of neuronal cells from the adult mouse brain.

Richards, L. J., Kilpatrick, T. J., & Bartlett, P. F. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.18.8591 · Cited by 544

In Vitro Expansion of a Multipotent Population of Human Neural Progenitor Cells

Carpenter, M. K., Xia, C., Hu, Z., Jackson, J. E., Sherman, S., Seiger, Å., & Wahlberg, L. U. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7098 · Cited by 500

EXPERIMENTAL STUDIES ON THE DEVELOPMENT OF THE THYMUS

Moore, M. A. S., & Owen, J. J. T. (1967) · The Journal of Experimental Medicine · doi:10.1084/jem.126.4.715 · Cited by 495

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

Shah, N. M. (1994) · Cell · doi:10.1016/0092-8674(94)90150-3 · Cited by 491

Can stem cells cross lineage boundaries?

Anderson, D. J., Gage, F. H., & Weissman, I. L. (2001) · Nature Medicine · doi:10.1038/86439 · Cited by 489

Identification of a lineage of multipotent hematopoietic progenitors

Morrison, S. J., Wandycz, A. M., Hemmati, H. D., Wright, D. E., & Weissman, I. L. (1997) · Development · doi:10.1242/dev.124.10.1929 · Cited by 482

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

Miyamoto, T., Weissman, I. L., & Akashi, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.13.7521 · Cited by 465

Proliferation, differentiation, and long-term culture of primary hippocampal neurons.

Ray, J., Peterson, D. A., Schinstine, M., & Gage, F. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3602 · Cited by 457

CYTOLOGICAL EVIDENCE FOR A RELATIONSHIP BETWEEN NORMAL HEMATOPOIETIC COLONY-FORMING CELLS AND CELLS OF THE LYMPHOID SYSTEM

Wu, A. M., Till, J. E., Siminovitch, L., & McCulloch, E. A. (1968) · The Journal of Experimental Medicine · doi:10.1084/jem.127.3.455 · Cited by 445

Stem cells in the adult mammalian central nervous system

Temple, S., & Álvarez-Buylla, A. (1999) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(99)80017-8 · Cited by 440

Development of CD8α-Positive Dendritic Cells from a Common Myeloid Progenitor

Traver, D. J., Akashi, K., Manz, M. G., Mérad, M., Miyamoto, T., Engleman, E. G., & Weissman, I. L. (2000) · Science · doi:10.1126/science.290.5499.2152 · Cited by 392

Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines

Kondo, M., Scherer, D. C., Miyamoto, T., King, A. G., Akashi, K., Sugamura, K., & Weissman, I. L. (2000) · Nature · doi:10.1038/35030112 · Cited by 382

Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation

Kilpatrick, T. J., & Bartlett, P. F. (1993) · Neuron · doi:10.1016/0896-6273(93)90316-j · Cited by 373

Isolation of Lineage-Restricted Neuronal Precursors from Multipotent Neuroepithelial Stem Cells

Mayer‐Pröschel, M., Kalyani, A. J., Mujtaba, T., & Rao, M. S. (1997) · Neuron · doi:10.1016/s0896-6273(00)80960-5 · Cited by 369

Searching for hematopoietic stem cells: evidence that Thy-1.1lo Lin- Sca-1+ cells are the only stem cells in C57BL/Ka-Thy-1.1 bone marrow.

Uchida, N., & Weissman, I. L. (1992) · The Journal of Experimental Medicine · doi:10.1084/jem.175.1.175 · Cited by 359

Isolation of two early B lymphocyte progenitors from mouse marrow: A committed Pre-Pre-B cell and a clonogenic Thy-1lo hematopoietic stem cell

Müller‐Sieburg, C. E., Whitlock, C. A., & Weissman, I. L. (1986) · Cell · doi:10.1016/0092-8674(86)90274-6 · Cited by 325

Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization

Morrison, S. J., Wright, D. E., & Weissman, I. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.5.1908 · Cited by 314

Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I

Grompe, M., Lindstedt, S., Al-Dhalimy, M., Kennaway, N. G., Papaconstantinou, J., Torres-Ramos, C. A., Ou, C.-N., & Finegold, M. (1995) · Nature Genetics · doi:10.1038/ng0895-453 · Cited by 312

Stem Cells and Pattern Formation in the Nervous System

Anderson, D. J. (2001) · Neuron · doi:10.1016/s0896-6273(01)00260-4 · Cited by 300

Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats

Brüstle, O., Choudhary, K., Karram, K., Huttner, A. J., Murray, K., Dubois-Dalcq, M. E., & McKay, R. D. G. (1998) · Nature Biotechnology · doi:10.1038/3481 · Cited by 299

Neuroepithelial Stem Cells from the Embryonic Spinal Cord: Isolation, Characterization, and Clonal Analysis

Kalyani, A. J., Hobson, K., & Rao, M. S. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8592 · Cited by 297

Bone marrow stromal cell lines with lymphopoietic activity express high levels of a pre-B neoplasia-associated molecule

Whitlock, C. A., Tidmarsh, G. F., Müller‐Sieburg, C. E., & Weissman, I. L. (1987) · Cell · doi:10.1016/0092-8674(87)90709-4 · Cited by 246

Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF

Kilpatrick, T. J., & Bartlett, P. F. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03653.1995 · Cited by 235

Experimental analysis of the origin of cell types in the development of the mouse thymus

Auerbach, R. (1961) · Developmental Biology · doi:10.1016/0012-1606(61)90051-3 · Cited by 223

Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle

Wright, D. E., Cheshier, S. H., Wagers, A. J., Randall, T. D., Christensen, J. L., & Weissman, I. L. (2001) · Blood · doi:10.1182/blood.v97.8.2278 · Cited by 208

Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer

Negrin, R. S., Atkinson, K., Leemhuis, T., Hanania, E. G., Juttner, C. A., Tierney, K., Hu, W. W., Johnston, L., Shizuru, J. A., Stockerl-Goldstein, K. E., et al. (2000) · Transplantation and Cellular Therapy · doi:10.1016/s1083-8791(00)70008-5 · Cited by 167

Bone marrow cells give rise to distinct cell clones within the thymus

Ezine, S., Weissman, I. L., & Rouse, R. V. (1984) · Nature · doi:10.1038/309629a0 · Cited by 143

Neural Crest Stem Cells Undergo Cell-Intrinsic Developmental Changes in Sensitivity to Instructive Differentiation Signals

White, P. M., Morrison, S. J., Orimoto, K., Kubu, C. J., Verdi, J. M., & Anderson, D. J. (2001) · Neuron · doi:10.1016/s0896-6273(01)00180-5 · Cited by 136

Integration of multiple instructive cues by neural crest stem cells reveals cell-intrinsic biases in relative growth factor responsiveness

Shah, N. M., & Anderson, D. J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11369 · Cited by 133

High doses of purified stem cells cause early hematopoietic recovery in syngeneic and allogeneic hosts.

Uchida, N., Tsukamoto, A., He, D., Friera, A. M., Scollay, R. G., & Weissman, I. L. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1681 · Cited by 132

Stem cell potential: Can anything make anything?

Morrison, S. J. (2001) · Current Biology · doi:10.1016/s0960-9822(00)00033-6 · Cited by 125

Transplantation of purified hematopoietic stem cells: requirements for overcoming the barriers of allogeneic engraftment.

Shizuru, J. A., Jerabek, L., Taylor-Edwards, C., & Weissman, I. L. (1996) · PubMed · Cited by 118

Transplantation with selected autologous peripheral blood CD34+Thy1+ hematopoietic stem cells (HSCs) in multiple myeloma

Michallet, M., Philip, T. O., Philip, I., Godinot, H., Sebban, C., Salles, G., Thiébaut, A., Biron, P., Lopez, F., Mazars, P., et al. (2000) · Experimental Hematology · doi:10.1016/s0301-472x(00)00169-7 · Cited by 111

Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: influence of colony-stimulating factors.

Metcalf, D. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.24.11310 · Cited by 109

Clonal remissions in acute nonlymphocytic leukemia: evidence for a multistep pathogenesis of the malignancy

Fialkow, P., Janssen, J. W. G., & Bartram, C. (1991) · Blood · doi:10.1182/blood.v77.7.1415.1415 · Cited by 97

Isolated rat cortical progenitor cells are maintained in division in vitro by membrane-associated factors

Temple, S., & Davis, A. A. (1994) · Development · doi:10.1242/dev.120.4.999 · Cited by 95

Grafting immortalized neurons to the CNS

Snyder, E. Y. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90018-3 · Cited by 92

Should Polymerase Chain Reaction Analysis to Detect Minimal Residual Disease in Patients With Chronic Myelogenous Leukemia Be Used in Clinical Decision Making?

Faderl, S. H., Talpaz, M., Kantarjian, H. M., & Estrov, Z. E. (1999) · Blood · doi:10.1182/blood.v93.9.2755.409a45_2755_2759 · Cited by 90

Purified hematopoietic stem cell grafts induce tolerance to alloantigens and can mediate positive and negative T cell selection

Shizuru, J. A., Weissman, I. L., Kernoff, R., Masek, M., & Scheffold, Y. C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.170279297 · Cited by 87

Translocation (8;21)(q22;q22) in Acute Nonlymphocytic Leukemia

Hagemeijer, A., Garson, O. M., & Kondo, K. (1984) · Cancer Genetics and Cytogenetics · doi:10.1016/s0165-4608(84)80007-2 · Cited by 75

Mechanisms of cell injury and death in cholestasis and hepatoprotection by ursodeoxycholic acid

Gores, G. J. (2000) · Journal of Hepatology · doi:10.1016/s0168-8278(00)80435-3 · Cited by 69

In vivo transplantation of mammalian neural crest cells into chick hosts reveals a new autonomic sublineage restriction

White, P. M., & Anderson, D. J. (1999) · Development · doi:10.1242/dev.126.19.4351 · Cited by 66

TOLERANCE OF ALLOGENEIC HEART GRAFTS IN MICE SIMULTANEOUSLY RECONSTITUTED WITH PURIFIED ALLOGENEIC HEMATOPOIETIC STEM CELLS1

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Quantification of PML‐RARα transcripts in acute promyelocytic leukaemia: explanation for the lack of sensitivity of RT‐PCR for the detection of minimal residual disease and induction of the leukaemia‐specific mRNA by alpha interferon

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