Cited by 530Neuroscience and Neuropharmacology ResearchDeep Brain Stimulation and Movement DisordersNeural dynamics and brain function

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Physiology and Pharmacology of Striatal Neurons

Kreitzer, Anatol C.·2009·Annual Review of Neuroscience

DOI 10.1146/annurev.neuro.051508.135422

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Abstract

The basal ganglia occupy the core of the forebrain and consist of evolutionarily conserved motor nuclei that form recurrent circuits critical for motivation and motor planning. The striatum is the main input nucleus of the basal ganglia and a key neural substrate for procedural learning and memory. The vast majority of striatal neurons are spiny GABAergic projection neurons, which exhibit slow but temporally precise spiking in vivo. Contributing to this precision are several different types of interneurons that constitute only a small fraction of total neuron number but play a critical role in regulating striatal output. This review examines the cellular physiology and modulation of striatal neurons that give rise to their unique properties and function.

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Yin, H. H., & Knowlton, B. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1919 · Cited by 2,402
Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop
Parent, A., & Hazrati, L.-N. (1995) · Brain Research Reviews · doi:10.1016/0165-0173(94)00007-c · Cited by 2,161
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Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E., et al. (2003) · Nature · doi:10.1038/nature02033 · Cited by 2,108
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Piomelli, D. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1247 · Cited by 1,957
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Schultz, W. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135722 · Cited by 1,415
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McGeorge, A. J., & Faull, R. L. M. (1989) · Neuroscience · doi:10.1016/0306-4522(89)90128-0 · Cited by 1,360

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Background
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Authors: Kreitzer, A. C.
Affiliations: University of California, San Francisco (US)
Corresponding author: Kreitzer, Anatol C.
ORCID: Kreitzer, Anatol C.
Venue: Annual Review of Neuroscience
Publisher: Annual Reviews
Published: 2009-06-01
Volume: 32
Issue: 1
Pages: 127-147
ISSN: 0147-006X (ISSN-L)
1545-4126
DOI: 10.1146/annurev.neuro.051508.135422
OpenAlex: W2110925924
Cited by: 530
References: 183
Citations by year: 2026: 15 · 2025: 18 · 2024: 33 · 2023: 47 · 2022: 31 · 2021: 33 · 2020: 41 · 2019: 36 · 2018: 31 · 2017: 42 · 2016: 28 · 2015: 33 · 2014: 36 · 2013: 25 · 2012: 29
FWCI: 2.28
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Neuroscience (publishedVersion)
PubMed (publishedVersion)
Funders: Pew Charitable Trusts
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords: striatum, basal ganglia, striatal neurons, medium spiny neurons, striatal interneurons, neuronal physiology, pharmacology, GABAergic neurons, striatal output, procedural learning, motor control, recurrent circuits
MeSH terms: Action Potentials, Animals, Basal Ganglia Diseases, Corpus Striatum, Humans, Interneurons, Neural Pathways, Neurons, Neuropeptides, Neurotransmitter Agents, Neuropil

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