Systemic Iron Homeostasis

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., & Kaplan, J. (2004) · Science · doi:10.1126/science.1104742 · Cited by 4,803

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

Nemeth, E., Rivera, S., Gabayan, V., Keller, C., Taudorf, S., Pedersen, B. K., & Ganz, T. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200420945 · Cited by 2,650 · cited 2×

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

Park, C. H., Valore, E. V., Waring, A. J., & Ganz, T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008922200 · Cited by 2,168

Two to tango: Regulation of Mammalian iron metabolism

Hentze, M. W., Muckenthaler, M. U., Galy, B., & Camaschella, C. (2010) · Cell · doi:10.1016/j.cell.2010.06.028 · Cited by 2,120

Identification of the haemoglobin scavenger receptor

Kristiansen, M., Graversen, J. H., Jacobsen, C., Sonne, O., Hoffman, H.-J., Law, S. K. A., & Moestrup, S. K. (2001) · Nature · doi:10.1038/35051594 · Cited by 1,712

A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload

Pigeon, C., Ilyin, G., Courselaud, B., Leroyer, P., Turlin, B., Brissot, P., & Loréal, O. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008923200 · Cited by 1,697

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., et al. (2000) · Nature · doi:10.1038/35001596 · Cited by 1,667

A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation

McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T. J., Farzaneh, F., et al. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80425-6 · Cited by 1,422

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

Nemeth, E., Valore, E. V., Territo, M., Schiller, G., Lichtenstein, A., & Ganz, T. (2003) · Blood · doi:10.1182/blood-2002-10-3235 · Cited by 1,417

Ferroptosis as a target for protection against cardiomyopathy

Fang, X., Wang, H., Han, D., Xie, E., Yang, X., Wei, J., Gu, S., Gao, F., Zhu, N., Yin, X., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1821022116 · Cited by 2,163

Anemia of inflammation

Weiss, G., Ganz, T., & Goodnough, L. T. (2019) · Blood · doi:10.1182/blood-2018-06-856500 · Cited by 1,219

Mechanisms of action of plant growth promoting bacteria

Olanrewaju, O. S., Glick, B. R., & Babalola, O. O. (2017) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-017-2364-9 · Cited by 1,203

The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease

Fang, X., Ardehali, H., Min, J., & Wang, F. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00735-4 · Cited by 1,121

Iron homeostasis in host defence and inflammation

Ganz, T., & Nemeth, E. (2015) · Nature Reviews Immunology · doi:10.1038/nri3863 · Cited by 843

Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis

Fang, X., Cai, Z., Wang, H., Han, D., Cheng, Q., Zhang, P., Gao, F., Yu, Y., Song, Z., Wu, Q., et al. (2020) · Circulation Research · doi:10.1161/circresaha.120.316509 · Cited by 779

Current understanding of iron homeostasis

Anderson, G. J., & Frazer, D. M. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.155804 · Cited by 688

Characterization of ferroptosis in murine models of hemochromatosis

Wang, H., An, P., Xie, E., Wu, Q., Fang, X., Gao, H., Zhang, Z., Li, Y., Wang, X., Zhang, J., et al. (2017) · Hepatology · doi:10.1002/hep.29117 · Cited by 662

Ironing out Ferroportin

Drakesmith, H., Nemeth, E., & Ganz, T. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.09.006 · Cited by 638

Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression

Bai, B., Wang, X., Li, Y., Chen, P.-C., Yu, K., Dey, K. K., Yarbro, J. M., Han, X., Lutz, B. M., Rao, S., et al. (2020) · Neuron · doi:10.1016/j.neuron.2019.12.015 · Cited by 565

Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis

Yu, Y., Jiang, L., Wang, H., Shen, Z., Cheng, Q., Zhang, P., Wang, J., Wu, Q., Fang, X., Duan, L., et al. (2020) · Blood · doi:10.1182/blood.2019002907 · Cited by 610

Anemia of Inflammation

Ganz, T. (2019) · New England Journal of Medicine · doi:10.1056/nejmra1804281 · Cited by 589

Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management

Cappellini, M. D., Comin‐Colet, J., de Francisco, A., Dignass, A., Doehner, W., Lam, C. S., Macdougall, I. C., Rogler, G., Camaschella, C., Kadir, R., et al. (2017) · American Journal of Hematology · doi:10.1002/ajh.24820 · Cited by 502

Overview of iron metabolism in health and disease

Dev, S., & Babitt, J. L. (2017) · Hemodialysis International · doi:10.1111/hdi.12542 · Cited by 499

Regulation of the Iron Homeostatic Hormone Hepcidin

Sangkhae, V., & Nemeth, E. (2017) · Advances in Nutrition · doi:10.3945/an.116.013961 · Cited by 454

Anemia of inflammation

Nemeth, E., & Ganz, T. (2014) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2014.04.005 · Cited by 401

Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease

Martín‐Bastida, A., Ward, R. J., Newbould, R. D., Piccini, P. P., Sharp, D. J., Kabba, C., Patel, M. C., Spino, M., Connelly, J., Tricta, F., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-01402-2 · Cited by 393

The IRP/IRE system in vivo: insights from mouse models

Wilkinson, N., & Pantopoulos, K. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00176 · Cited by 366

Targeting iron metabolism in drug discovery and delivery

Crielaard, B. J., Lammers, T., & Rivella, S. (2017) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.248 · Cited by 352

Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition

Rémond, D., Shahar, D. R., Gille, D., Pinto, P., Kachal, J., Peyron, M., dos Santos, C. N., Walther, B., Bordoni, A., Dupont, D., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.4030 · Cited by 351

Scientific Opinion on Dietary Reference Values for iron

EFSA Panel on Dietetic Products, N. A. A. (. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.4254 · Cited by 338

Iron metabolism: pathophysiology and pharmacology

Roemhild, K., von Maltzahn, F., Weiskirchen, R., Knüchel, R., von Stillfried, S. F., & Lammers, T. (2021) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2021.05.001 · Cited by 329

M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity

Khan, N., Downey, J., Sanz, J., Kaufmann, E., Blankenhaus, B., Pacis, A., Pernet, E., Ahmed, E. A., Cardoso, S., Nijnik, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.09.062 · Cited by 306

Iron mediated toxicity and programmed cell death: A review and a re-examination of existing paradigms

Eid, R., Arab, N. T. T., & Greenwood, M. T. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.12.002 · Cited by 297

Limitations of Serum Ferritin in Diagnosing Iron Deficiency in Inflammatory Conditions

Dignass, A. U., Farrag, K., & Stein, J. M. (2018) · International Journal of Chronic Diseases · doi:10.1155/2018/9394060 · Cited by 309

Anemia: progress in molecular mechanisms and therapies

Sankaran, V. G., & Weiss, M. J. (2015) · Nature Medicine · doi:10.1038/nm.3814 · Cited by 290

Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis

Wu, A., Feng, B., Yu, J., Yan, L., Che, L., Zhuo, Y., Luo, Y., Yu, B., Wu, D., & Chen, D. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102131 · Cited by 265

Iron Metabolism, Ferroptosis, and the Links With Alzheimer’s Disease

Yan, N., & Zhang, J. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.01443 · Cited by 256

Renal Clearable Ultrasmall Single-Crystal Fe Nanoparticles for Highly Selective and Effective Ferroptosis Therapy and Immunotherapy

Liang, H., Wu, X., Zhao, G., Feng, K., Ni, K., & Sun, X. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.1c07471 · Cited by 254

Hepcidin regulation in the anemia of inflammation

Wang, C., & Babitt, J. L. (2016) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000236 · Cited by 261

Mechanisms of red blood cell transfusion‐related immunomodulation

Remy, K. E., Hall, M. W., Cholette, J. M., Juffermans, N. P., Nicol, K. K., Doctor, A., Blumberg, N., Spinella, P. C., Norris, P. J., Dahmer, M. K., et al. (2018) · Transfusion · doi:10.1111/trf.14488 · Cited by 250

Oxidative Stress and the Homeodynamics of Iron Metabolism

Bresgen, N., & Eckl, P. (2015) · Biomolecules · doi:10.3390/biom5020808 · Cited by 247

Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway

Chen, Y., Zhang, P., Chen, W., & Chen, G. (2020) · Immunology Letters · doi:10.1016/j.imlet.2020.06.005 · Cited by 247

The cell biology of the hepatocyte: A membrane trafficking machine

Schulze, R. J., Schott, M. B., Casey, C. A., Tuma, P. L., & McNiven, M. A. (2019) · The Journal of Cell Biology · doi:10.1083/jcb.201903090 · Cited by 281

Mechanisms Linking Glucose Homeostasis and Iron Metabolism Toward the Onset and Progression of Type 2 Diabetes

Fernández‐Real, J. M., McClain, D. A., & Manco, M. (2015) · Diabetes Care · doi:10.2337/dc14-3082 · Cited by 245

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents

Aßhoff, M., Petzer, V., Warr, M. R., Haschka, D., Tymoszuk, P., Demetz, E., Seifert, M., Posch, W., Nairz, M., Maciejewski, P., et al. (2017) · Blood · doi:10.1182/blood-2016-09-740092 · Cited by 241

Impact of Inflammation on Ferritin, Hepcidin and the Management of Iron Deficiency Anemia in Chronic Kidney Disease

Ueda, N., & Takasawa, K. (2018) · Nutrients · doi:10.3390/nu10091173 · Cited by 251

A role of PIEZO1 in iron metabolism in mice and humans

Ma, S., Dubin, A. E., Zhang, Y., Mousavi, S. A. R., Wang, Y., Coombs, A. M., Loud, M., Andolfo, I., & Patapoutian, A. (2021) · Cell · doi:10.1016/j.cell.2021.01.024 · Cited by 232

The ins and outs of bacterial iron metabolism

Frawley, E. R., & Fang, F. C. (2014) · Molecular Microbiology · doi:10.1111/mmi.12709 · Cited by 234

Basics and principles of cellular and systemic iron homeostasis

Katsarou, A., & Pantopoulos, K. (2020) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2020.100866 · Cited by 234

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

Canali, S., Zumbrennen‐Bullough, K. B., Core, A. B., Wang, C., Nairz, M., Bouley, R., Świrski, F. K., & Babitt, J. L. (2016) · Blood · doi:10.1182/blood-2016-06-721571 · Cited by 226

Iron and copper: critical executioners of ferroptosis, cuproptosis and other forms of cell death

Li, Y., Du, Y., Zhou, Y., Chen, Q., Luo, Z., Ren, Y., Chen, X., & Chen, G. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01267-1 · Cited by 225

Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study

Verstovšek, S., Gerds, A. T., Vannucchi, A. M., Al‐Ali, H. K., Lavie, D., Kuykendall, A. T., Grosicki, S., Iurlo, A., Goh, Y. T., Lazaroiu, M. C., et al. (2023) · The Lancet · doi:10.1016/s0140-6736(22)02036-0 · Cited by 220

Effects of maternal iron status on placental and fetal iron homeostasis

Sangkhae, V., Fisher, A. L., Wong, S., Koenig, M. D., Tussing-Humphreys, L., Chu, A., Lelić, M., Ganz, T., & Nemeth, E. (2019) · Journal of Clinical Investigation · doi:10.1172/jci127341 · Cited by 198

General Overview of Klebsiella pneumonia: Epidemiology and the Role of Siderophores in Its Pathogenicity

Abbas, R., Chakkour, M., Dine, H. Z. E., Obaseki, E., Obeid, S. T., Jezzini, A., Ghssein, G., & Ezzeddine, Z. (2024) · Biology · doi:10.3390/biology13020078 · Cited by 227

Iron homeostasis in host and gut bacteria – a complex interrelationship

Seyoum, Y., Baye, K., & Humblot, C. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1874855 · Cited by 204

Iron Balance and the Role of Hepcidin in Chronic Kidney Disease

Ganz, T., & Nemeth, E. (2016) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2016.02.001 · Cited by 195

Modern iron replacement therapy: clinical and pathophysiological insights

Girelli, D., Ugolini, S., Busti, F., Marchi, G., & Castagna, A. (2017) · International Journal of Hematology · doi:10.1007/s12185-017-2373-3 · Cited by 196

Iron Overload, Oxidative Stress, and Ferroptosis in the Failing Heart and Liver

Mancardi, D., Mezzanotte, M., Arrigo, E., Barinotti, A., & Roetto, A. (2021) · Antioxidants · doi:10.3390/antiox10121864 · Cited by 188

Fluorescent probes for ferroptosis bioimaging: advances, challenges, and prospects

Yin, J., Zhan, J., Hu, Q., Huang, S., & Lin, W. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00454b · Cited by 183

Physiology and pathophysiology of iron in hemoglobin-associated diseases

Coates, T. D. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.03.039 · Cited by 184

Iron bioavailability from food fortification to precision nutrition. A review

Blanco-Rojo, R., & Vaquero, M. P. (2018) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2018.04.015 · Cited by 190

Ferroptosis and ferritinophagy in diabetes complications

He, J., Li, Z., Xia, P., Shi, A., FuChen, X., Zhang, J., & Yu, P. (2022) · Molecular Metabolism · doi:10.1016/j.molmet.2022.101470 · Cited by 187

Iron Accumulation and Lipid Peroxidation in the Aging Retina: Implication of Ferroptosis in Age-Related Macular Degeneration

Zhao, T., Guo, X., & Sun, Y. (2021) · Aging and Disease · doi:10.14336/ad.2020.0912 · Cited by 180

Iron overload inhibits osteogenic commitment and differentiation of mesenchymal stem cells via the induction of ferritin

Balogh, E., Szilágyi-Tolnai, E., Nagy, B., Nagy, B., Balla, G., Balla, J., & Jeney, V. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.06.003 · Cited by 176

Iron export through the transporter ferroportin 1 is modulated by the iron chaperone PCBP2

Yanatori, I., Richardson, D. R., Imada, K., & Kishi, F. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.721936 · Cited by 170

Iron transport proteins: Gateways of cellular and systemic iron homeostasis

Knutson, M. D. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r117.786632 · Cited by 177

Crossing the Iron Gate: Why and How Transferrin Receptors Mediate Viral Entry

Wessling‐Resnick, M. (2018) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-082117-051749 · Cited by 164

Bioinorganics and Wound Healing

Dalisson, B., & Barralet, J. E. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900764 · Cited by 168

The effect of iron deficiency and anaemia on women’s health

Benson, C. S., Shah, A., Stanworth, S. J., Frise, C., Spiby, H., Lax, S. J., Murray, J. A. H., & Klein, A. A. (2021) · Anaesthesia · doi:10.1111/anae.15405 · Cited by 161

Iron Metabolism in Cardiovascular Disease: Physiology, Mechanisms, and Therapeutic Targets

Sawicki, K. T., Jesus, A. D., & Ardehali, H. (2023) · Circulation Research · doi:10.1161/circresaha.122.321667 · Cited by 168

The Aging of Iron Man

Ashraf, A., Clark, M., & So, P. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00065 · Cited by 163

Intestinal DMT1 is critical for iron absorption in the mouse but is not required for the absorption of copper or manganese

Shawki, A., Anthony, S., Nose, Y., Engevik, M. A., Niespodzany, E. J., Barrientos, T., Öhrvik, H., Worrell, R. T., Thiele, D. J., & Mackenzie, B. (2015) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00160.2015 · Cited by 156

Iron Deficiency in Heart Failure: Mechanisms and Pathophysiology

Alnuwaysir, R. I. S., Hoes, M. F., van Veldhuisen, D. J., van der Meer, P., & Beverborg, N. G. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010125 · Cited by 175

Magnetic nanoparticles: material engineering and emerging applications in lithography and biomedicine

Bao, Y., Wen, T., Samia, A. C. S., Khandhar, A. P., & Krishnan, K. M. (2015) · Journal of Materials Science · doi:10.1007/s10853-015-9324-2 · Cited by 159

The role of iron in host–microbiota crosstalk and its effects on systemic glucose metabolism

Mayneris‐Perxachs, J., Moreno‐Navarrete, J. M., & Fernández‐Real, J. M. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-022-00721-3 · Cited by 161

Chemical tools for detecting Fe ions

Hirayama, T., & Nagasawa, H. (2016) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.16-70 · Cited by 154

Potentiation of hydrogen peroxide toxicity: From catalase inhibition to stable DNA-iron complexes

Mahaseth, T., & Kuzminov, A. (2016) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2016.08.006 · Cited by 159

Iron Homeostasis Disorder and Alzheimer’s Disease

Peng, Y., Chang, X., & Lang, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212442 · Cited by 146

Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin

Lim, P. J., Duarte, T. L., Arezes, J., Garcia-Santos, D., Hamdi, A., Pasricha, S.-R., Armitage, A. E., Mehta, H., Wideman, S., Santos, A. G., et al. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0063-6 · Cited by 147

Iron metabolism and type 2 diabetes mellitus: A meta‐analysis and systematic review

Liu, J., Li, Q., Yang, Y., & Ma, L. (2020) · Journal of Diabetes Investigation · doi:10.1111/jdi.13216 · Cited by 159

Dietary strategies for improving iron status: balancing safety and efficacy

Prentice, A. M., Mendoza, Y. A., Pereira, D. I. A., Cerami, C., Wegmüller, R., Constable, A., & Spieldenner, J. (2016) · Nutrition Reviews · doi:10.1093/nutrit/nuw055 · Cited by 150

Risk of Infection Associated With Administration of Intravenous Iron

Shah, A., Donovan, K., Seeley, C., Dickson, E. A., Palmer, A. J. R., Doree, C. J., Brunskill, S. J., Reid, J., Acheson, A. G., Sugavanam, A., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.33935 · Cited by 143

Ironing out mechanisms of iron homeostasis and disorders of iron deficiency

Koleini, N., Shapiro, J. S., Geier, J., & Ardehali, H. (2021) · Journal of Clinical Investigation · doi:10.1172/jci148671 · Cited by 161

Induction and application of ferroptosis in cancer therapy

Nie, Q. H., Hu, Y., Yu, X. H., Li, X., & Fang, X. (2022) · Cancer Cell International · doi:10.1186/s12935-021-02366-0 · Cited by 146

Iron deficiency in the elderly population, revisited in the hepcidin era

Busti, F., Campostrini, N., Martinelli, N., & Girelli, D. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00083 · Cited by 137

Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6

Canali, S., Wang, C., Zumbrennen‐Bullough, K. B., Bayer, A., & Babitt, J. L. (2017) · American Journal of Hematology · doi:10.1002/ajh.24888 · Cited by 133

Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc

Mitchell, C. J., Shawki, A., Ganz, T., Nemeth, E., & Mackenzie, B. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00348.2013 · Cited by 132

Intestinal Iron Absorption

McKie, A. T., & Simpson, R. J. (2011) · Humana Press eBooks · doi:10.1007/978-1-60327-485-2_6 · Cited by 133

Serum or plasma ferritin concentration as an index of iron deficiency and overload

Garcia‐Casal, M. N., Pasricha, S., Martinez, R. X., Lopez-Perez, L., & Peña‐Rosas, J. P. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011817.pub2 · Cited by 149

Ferric Carboxymaltose: A Review of Its Use in Iron Deficiency

Keating, G. M. (2014) · Drugs · doi:10.1007/s40265-014-0332-3 · Cited by 128

Pharmacological Targeting of the Hepcidin/Ferroportin Axis

Sebastiani, G., Wilkinson, N., & Pantopoulos, K. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00160 · Cited by 127

Iron metabolism and related genetic diseases: A cleared land, keeping mysteries

Brissot, P., & Loréal, O. (2015) · Journal of Hepatology · doi:10.1016/j.jhep.2015.11.009 · Cited by 131

Immunoassay for human serum erythroferrone

Ganz, T., Jung, G., Naeim, A., Ginzburg, Y., Pakbaz, Z., Walter, P. B., Kautz, L., & Nemeth, E. (2017) · Blood · doi:10.1182/blood-2017-04-777987 · Cited by 125

How we manage iron overload in sickle cell patients

Coates, T. D., & Wood, J. C. (2017) · British Journal of Haematology · doi:10.1111/bjh.14575 · Cited by 124

Impact and management of iron deficiency and iron deficiency anemia in women’s health

Mirza, F., Kadir, R. A., Breymann, C., Fraser, I. S., & Taher, A. T. (2018) · Expert Review of Hematology · doi:10.1080/17474086.2018.1502081 · Cited by 136

-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies

Rivella, S. (2015) · Haematologica · doi:10.3324/haematol.2014.114827 · Cited by 125

Systemic iron homeostasis and erythropoiesis

Papanikolaou, G. V., & Pantopoulos, K. (2017) · IUBMB Life · doi:10.1002/iub.1629 · Cited by 128

Iron deficiency anemia in celiac disease

Freeman, H. J. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i31.9233 · Cited by 122

Epidemiological associations between iron and cardiovascular disease and diabetes

Basuli, D., Stevens, R. G., Torti, F. M., & Torti, S. V. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00117 · Cited by 124

Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load

Fillebeen, C., Charlebois, E., Wagner, J., Katsarou, A., Mui, J., Vali, H., Garcia‐Santos, D., Ponka, P., Presley, J. F., & Pantopoulos, K. (2018) · Blood · doi:10.1182/blood-2018-05-850404 · Cited by 124

Iron supplementation and iron-fortified foods: a review

Man, Y., Xu, T., Adhikari, B., Zhou, C., Wang, Y., & Wang, B. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1876623 · Cited by 139

Iron and oxidative stress in cardiomyopathy in thalassemia

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