Search for natural products related to regeneration of the neuronal network

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., Hansen, L. A., & Katzman, R. (1991) · Annals of Neurology · doi:10.1002/ana.410300410 · Cited by 4,397 · see citing works

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Games, D., Adams, D., Alessandrini, R., Barbour, R., Borthelette, P., Blackwell, C., Carr, T., Clemens, J., Donaldson, T., Gillespie, F., et al. (1995) · Nature · doi:10.1038/373523a0 · Cited by 2,516 · see citing works

Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

DeKosky, S. T., & Scheff, S. W. (1990) · Annals of Neurology · doi:10.1002/ana.410270502 · Cited by 2,376 · see citing works

Amyloid β protein forms ion channels: implications for Alzheimer's disease pathophysiology

LIN, H., Bhatia, R., & Lal, R. (2001) · The FASEB Journal · doi:10.1096/fj.01-0377com · Cited by 641 · see citing works

DEGRADATION OF GINSENOSIDES IN HUMANS AFTER ORAL ADMINISTRATION

Tawab, M. A., Bahr, U., Karas, M., Wurglics, M., & Schubert‐Zsilavecz, M. (2003) · Drug Metabolism and Disposition · doi:10.1124/dmd.31.8.1065 · Cited by 440 · see citing works

Neuritic regeneration and synaptic reconstruction induced by withanolide A

Kuboyama, T., Tohda, C., & Komatsu, K. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706122 · Cited by 339 · see citing works

The morphological phenotype of β-amyloid plaques and associated neuritic changes in Alzheimer’s disease

Dickson, T. C., & Vickers, J. C. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00169-5 · Cited by 294 · see citing works

Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide _1–42 - and Lipopolysaccharide-Activated Microglia

Xie, Z., Wei, M., Morgan, T. E., Fabrizio, P., Han, D., Finch, C. E., & Longo, V. D. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03484.2002 · Cited by 272 · see citing works

β-Amyloid Fragment 25–35 Causes Mitochondrial Dysfunction in Primary Cortical Neurons

Casley, C. S., Land, J. M., Sharpe, M. A., Clark, J. B., Duchen, M. R., & Canevari, L. (2002) · Neurobiology of Disease · doi:10.1006/nbdi.2002.0516 · Cited by 205 · see citing works

Withanolide Derivatives from the Roots of Withania somnifera and Their Neurite Outgrowth Activities.

Zhao, J., Nakamura, N., Hattori, M., Kuboyama, T., Tohda, C., & Komatsu, K. (2002) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.50.760 · Cited by 194 · see citing works

Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in alzheimer's disease

Heinonen, O., Soininen, H., Sorvari, H., Kosunen, O., Paljärvi, L., Koivisto, E., & Riekkinen, P. J. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00422-2 · Cited by 186 · see citing works

Role of Human IntestinalPrevotella orisin Hydrolyzing Ginseng Saponins

Hasegawa, H., Sung, J.-H., & Benno, Y. (1997) · Planta Medica · doi:10.1055/s-2006-957729 · Cited by 171 · see citing works

Caffeine attenuates scopolamine-induced memory impairment in humans

Reidel, W., Hogervorst, E., Leboux, R., Verhey, F., van Praag, H., & Jolles, J. (1995) · Psychopharmacology · doi:10.1007/bf02246090 · Cited by 152 · see citing works

Characterization of neuronal dystrophy induced by fibrillar amyloid β: implications for Alzheimer’s disease

Grace, E. A., Rabiner, C. A., & Busciglio, J. A. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00241-5 · Cited by 151 · see citing works

Studies on Absorption, Distribution, Excretion and Metabolism of Ginseng Saponins. VII. Comparison of the Decomposition Modes of Ginsenoside-Rb1 and -Rb2 in the Digestive Tract of Rats.

Karikura, M., Miyase, T., Tanizawa, H., TANIYAMA, T., & Takino, Y. (1991) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.39.2357 · Cited by 148 · see citing works

Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha

Kuboyama, T., Tohda, C., Zhao, J., Nakamura, N., Hattori, M., & Komatsu, K. (2002) · Neuroreport · doi:10.1097/00001756-200210070-00005 · Cited by 146 · see citing works

Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice

Mook‐Jung, I., Hong, H., Boo, J. H., Lee, K. H., Yun, S. H., Cheong, M. Y., Joo, I.-S., Huh, K., & Jung, M. W. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1045 · Cited by 144 · see citing works

Aβ(25–35)-Induced Memory Impairment, Axonal Atrophy, and Synaptic Loss are Ameliorated by M1, A Metabolite of Protopanaxadiol-Type Saponins

Tohda, C., Matsumoto, N., Zou, K., Meselhy, M. R., & Komatsu, K. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300388 · Cited by 139 · see citing works

Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. II. The absorption, distribution and excretion of ginsenoside Rg1 in the rat.

Odani, T., Tanizawa, H., & Takino, Y. (1983) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.31.292 · Cited by 124 · see citing works

Aberrant Activation of Focal Adhesion Proteins Mediates Fibrillar Amyloid β-Induced Neuronal Dystrophy

Grace, E. A., & Busciglio, J. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-02-00493.2003 · Cited by 113 · see citing works

Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells

Tohda, C., Kuboyama, T., & Komatsu, K. (2000) · Neuroreport · doi:10.1097/00001756-200006260-00035 · Cited by 109 · see citing works

Comparative Study on Triterpene Saponins of Ginseng Drugs

Zhu, S., Zou, K., Fushimi, H., Cai, S., & Komatsu, K. (2004) · Planta Medica · doi:10.1055/s-2004-827192 · Cited by 98 · see citing works

Neuritic degeneration in the hippocampus and amygdala in Parkinson’s disease in relation to Alzheimer pathology

Mattila, P., Rinne, J., Helenius, H., & Röyttä, M. (1999) · Acta Neuropathologica · doi:10.1007/s004010051064 · Cited by 95 · see citing works

Neurotrophic activity of honokiol on the cultures of fetal rat cortical neurons

Fukuyama, Y., Nakade, K., Minoshima, Y., Yokoyama, R., Zhai, H., & Mitsumoto, Y. (2002) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(02)00112-9 · Cited by 93 · see citing works

Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. III. The absorption, distribution and excretion of ginsenoside Rb1 in the rat.

Odani, T., Tanizawa, H., & Takino, Y. (1983) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.31.1059 · Cited by 92 · see citing works

The cortical neuritic pathology of Huntington's disease

Jackson, M., Gentleman, S. M., Lennox, G. G., Ward, L., Gray, T. B., Randall, K., Morrell, K., & Lowe, J. S. (1995) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1995.tb01024.x · Cited by 89 · see citing works

Donepezil, a centrally acting acetylcholinesterase inhibitor, alleviates learning deficits in hypocholinergic models in rats

Ogura, H., Kosasa, T., Kuriya, Y., & Yamanishi, Y. (2000) · Methods and Findings in Experimental and Clinical Pharmacology · doi:10.1358/mf.2000.22.2.796070 · Cited by 81 · see citing works

Neuritogenic Effect of Natural Iridoid Compounds on PC12h Cells and Its Possible Relation to Signaling Protein Kinases.

Yamazaki, M., Chiba, K., & Mohri, T. (1996) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.19.791 · Cited by 80 · see citing works

Dammarane-type Triterpene Saponins from Panax japonicus

Zou, K., Zhu, S., Tohda, C., Cai, & Komatsu, K. (2002) · Journal of Natural Products · doi:10.1021/np010354j · Cited by 67 · see citing works

Trigonelline-Induced Neurite Outgrowth in Human Neuroblastoma SK-N-SH Cells.

Tohda, C., Nakamura, N., Komatsu, K., & Hattori, M. (1999) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.22.679 · Cited by 62 · see citing works

Dammarane-Type Saponins from Panax japonicus and Their Neurite Outgrowth Activity in SK-N-SH Cells

Zou, K., Zhu, S., Meselhy, M. R., Tohda, C., Cai, S., & Komatsu, K. (2002) · Journal of Natural Products · doi:10.1021/np0201117 · Cited by 61 · see citing works

Potentiation of nerve growth factor-action by picrosides I and II, natural iridoids, in PC12D cells

Li, P., Matsunaga, K., Yamakuni, T., & Ohizumi, Y. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00662-2 · Cited by 57 · see citing works

Substrate‐Bound β‐Amyloid Peptides Inhibit Cell Adhesion and Neurite Outgrowth in Primary Neuronal Cultures

Postuma, R. B., He, W., Nunan, J., Beyreuther, K. T., Masters, C. L., Barrow, C. J., & Small, D. H. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.741122.x · Cited by 56 · see citing works

Ginseng improves strategic learning by normal and brain-damaged rats

Zhao, R., & McDaniel, W. F. (1998) · Neuroreport · doi:10.1097/00001756-199805110-00066 · Cited by 56 · see citing works

Red ginseng ameliorated place navigation deficits in young rats with hippocampal lesions and aged rats

Zhong, Y., Nishijo, H., Uwano, T., Tamura, R., Kawanishi, K., & Ono, T. (2000) · Physiology & Behavior · doi:10.1016/s0031-9384(00)00206-7 · Cited by 55 · see citing works

Neuroaxonal pathology in Creutzfeldt-Jakob disease

Liberski, P. P., & Budka, H. (1999) · Acta Neuropathologica · doi:10.1007/s004010050995 · Cited by 55 · see citing works

Proliferative effect of ginseng saponin on neurite extension of primary cultured neurons of the rat cerebral cortex

Sugaya, A., Yuzurihara, M., Tsuda, T., Yasuda, K., Kajiwara, K., & Sugaya, E. (1988) · Journal of Ethnopharmacology · doi:10.1016/0378-8741(88)90125-0 · Cited by 48 · see citing works

Nardosinone, a novel enhancer of nerve growth factor in neurite outgrowth from PC12D cells

Li, P., Matsunaga, K., Yamamoto, K., Yoshikawa, R., Kawashima, K., & Ohizumi, Y. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00629-1 · Cited by 47 · see citing works

Malonylginsenoside Rb1 Potentiates Nerve Growth Factor (NGF)-Induced Neurite Outgrowth of Cultured Chick Embryonic Dorsal Root Ganglia.

Nishiyama, N., Cho, S.-I., KITAGAWA, I., & Saito, H. (1994) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.17.509 · Cited by 47 · see citing works

Axonal and Dendritic Extension by Protopanaxadiol-Type Saponins From Ginseng Drugs in SK-N-SH Cells

Tohda, C., Matsumoto, N., Zou, K., Meselhy, M. R., & Komatsu, K. (2002) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.90.254 · Cited by 46 · see citing works

POTENTIATION OF THE NGF-MEDIATED NERVE FIBER OUTGROWTH BY GINSENOSIDE Rb1 IN ORGAN CULTURES OF CHICKEN DORSAL ROOT GANGLIA

Saitō, H., Suda, K., Schwab, M. E., & Thoenen, H. (1977) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.27.445 · Cited by 31 · see citing works

(−)-3,5-Dicaffeoyl-muco-quinic acid isolated from Aster scaber contributes to the differentiation of PC12 cells: through tyrosine kinase cascade signaling

Hur, J. Y., Lee, P., Kim, H., Kang, I., Lee, K. R., & Kim, S. Y. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.178 · Cited by 31 · see citing works

Kaffee und Gesundheit

Czok, G. (1977) · Zeitschrift für Ernährungswissenschaft · doi:10.1007/bf02023704 · Cited by 10 · see citing works

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

Mirjalili, M. H., Moyano, E., Bonfill, M., Cusido, R. M., & Palazón, J. (2009) · Molecules · doi:10.3390/molecules14072373 · Cited by 657 · see citing works

Coffee and its Consumption: Benefits and Risks

Butt, M. S., & Sultan, M. T. (2011) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390903586412 · Cited by 614 · see citing works

Coffee: Biochemistry and Potential Impact on Health

Ludwig, I. A., Clifford, M. N., Lean, M. E. J., Ashihara, H., & Crozier, A. (2014) · Food Funct. · doi:10.1039/c4fo00042k · Cited by 537 · see citing works

Withania somnifera: an Indian ginseng

Kulkarni, S. K., & Dhir, A. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.09.011 · Cited by 416 · see citing works

Trigonelline: A Plant Alkaloid with Therapeutic Potential for Diabetes and Central Nervous System Disease

Zhou, J., Chan, L., & Zhou, S. (2012) · Current Medicinal Chemistry · doi:10.2174/092986712801323171 · Cited by 395 · see citing works

Coffee Constituents

Farah, A. (2012) · Coffee · doi:10.1002/9781119949893.ch2 · Cited by 330 · see citing works

Plants traditionally used in age related brain disorders—A survey of ethnobotanical literature

Adams, M. A., Gmünder, F., & Hamburger, M. O. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.07.016 · Cited by 328 · see citing works

Neuroprotective Effects of Coffee Bioactive Compounds: A Review

Socała, K., Szopa, A., Serefko, A., Poleszak, E., & Właź, P. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms22010107 · Cited by 263 · see citing works

Panax Ginseng Enhances Cognitive Performance in Alzheimer Disease

Lee, S., Chu, K., Sim, J.-Y., Heo, J., & Kim, M. (2008) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e31816c92e6 · Cited by 244 · see citing works

Neuroprotective Herbs for the Management of Alzheimer’s Disease

Gregory, J., Vengalasetti, Y. V., Bredesen, D. E., & Rao, R. V. (2021) · Biomolecules · doi:10.3390/biom11040543 · Cited by 238 · see citing works

Ayurvedic medicinal plants for Alzheimer’s disease: A review

Rao, R. V., Descamps, O., John, V., & Bredesen, D. E. (2012) · Alzheimer's Research & Therapy · doi:10.1186/alzrt125 · Cited by 213 · see citing works

Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease

Agis-Torres, A., Sollhuber, M., Fernandez, M., & Sanchez-Montero, J. M. (2014) · Current Neuropharmacology · doi:10.2174/1570159x113116660047 · Cited by 202 · see citing works

Fast simultaneous analysis of caffeine, trigonelline, nicotinic acid and sucrose in coffee by liquid chromatography–mass spectrometry

Perrone, D., Donangelo, C. M., & Farah, A. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.03.012 · Cited by 190 · see citing works

The Role of Phytochemicals in the Treatment and Prevention of Dementia

Howes, M. R., & Perry, E. K. (2011) · Drugs & Aging · doi:10.2165/11591310-000000000-00000 · Cited by 187 · see citing works

Withanoside IV and its active metabolite, sominone, attenuate Aβ(25–35)‐induced neurodegeneration

Kuboyama, T., Tohda, C., & Komatsu, K. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04664.x · Cited by 171 · see citing works

Diosgenin is an exogenous activator of 1,25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice

Tohda, C., Urano, T., Umezaki, M., Nemere, I., & Kuboyama, T. (2012) · Scientific Reports · doi:10.1038/srep00535 · Cited by 167 · see citing works

Medicinal Plants and Dementia Therapy: Herbal Hopes for Brain Aging?

Perry, E. K., & Howes, M. R. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00202.x · Cited by 160 · see citing works

Reductions in levels of the Alzheimer's amyloid β peptide after oral administration of ginsenosides

Chen, F., Eckman, E. A., & Eckman, C. B. (2006) · The FASEB Journal · doi:10.1096/fj.05-5530fje · Cited by 160 · see citing works

Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse

Rajasankar, S., Manivasagam, T., Venkatachalam, S., Prakash, S., Muthusamy, R., Krishnamurti, A., & Surendran, S. (2009) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2009.08.003 · Cited by 161 · see citing works

Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection

Chaurasiya, N. D., Uniyal, G. C., Lal, P., Misra, L., Sangwan, R. S., Tuli, R., & Sangwan, R. S. (2007) · Phytochemical Analysis · doi:10.1002/pca.1029 · Cited by 146 · see citing works

Establishment of cell suspension cultures of Withania somnifera for the production of withanolide A

Nagella, P., & Murthy, H. N. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.03.078 · Cited by 143 · see citing works

Ashwagandha leaf extract: A potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease

Rajasankar, S., Manivasagam, T., & Surendran, S. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.02.044 · Cited by 140 · see citing works

Flavors of the future: Health benefits of flavor precursors and volatile compounds in plant foods

Ayseli, M. T., & Ayseli, Y. I. (2015) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2015.11.005 · Cited by 136 · see citing works

Neuroprotective role of Withania somnifera root extract in maneb-paraquat induced mouse model of parkinsonism

Prakash, J., Yadav, S. K., Chouhan, S., & Singh, S. P. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1005-4 · Cited by 128 · see citing works

Neurotrophic Natural Products: Chemistry and Biology

Xu, J., Lacoske, M. H., & Theodorakis, E. A. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201302268 · Cited by 124 · see citing works

A Review on Biosynthesis, Analytical Techniques, and Pharmacological Activities of Trigonelline as a Plant Alkaloid

Mohamadi, N., Sharififar, F., Pournamdari, M., & Ansari, M. (2017) · Journal of Dietary Supplements · doi:10.1080/19390211.2017.1329244 · Cited by 126 · see citing works

Withanolide A Biogeneration in in Vitro Shoot Cultures of Ashwagandha (Withania somnifera DUNAL), a Main Medicinal Plant in Ayurveda

Sangwan, R. S., Chaurasiya, N. D., Lal, P., Misra, L., Uniyal, G. C., Tuli, R., & Sangwan, R. S. (2007) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.55.1371 · Cited by 118 · see citing works

Trigonelline Is a Novel Phytoestrogen in Coffee Beans ,

Allred, K. F., Yackley, K. M., Vanamala, J. K. P., & Allred, C. D. (2009) · Journal of Nutrition · doi:10.3945/jn.109.108001 · Cited by 117 · see citing works

Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus

Tohda, C., Tamura, T., Matsuyama, S., & Komatsu, K. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706865 · Cited by 115 · see citing works

Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera’s key metabolite withaferin A

Grover, A., Shandilya, A., Punetha, A., Bisaria, V. S., & Sundar, D. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-s4-s25 · Cited by 113 · see citing works

Trigonelline and related nicotinic acid metabolites: occurrence, biosynthesis, taxonomic considerations, and their roles in planta and in human health

Ashihara, H., Ludwig, I. A., Katahira, R., Yokota, T., Fujimura, T., & Crozier, A. (2015) · Phytochemistry Reviews · doi:10.1007/s11101-014-9375-z · Cited by 110 · see citing works

Determination of withaferin A and withanolide A in mice plasma using high-performance liquid chromatography-tandem mass spectrometry: Application to pharmacokinetics after oral administration of Withania somnifera aqueous extract

Patil, D., Gautam, M., Mishra, S. K., Suresh, K., Gairola, S., Jadhav, S. S., Pawar, S., & Patwardhan, B. (2013) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2013.03.001 · Cited by 108 · see citing works

Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents

Satheeshkumar, N., Mukherjee, P. K., Bhadra, S., & Saha, B. P. (2009) · Phytomedicine · doi:10.1016/j.phymed.2009.06.006 · Cited by 107 · see citing works

Pyridine alkaloids with activity in the central nervous system

Lin, S. X., Curtis, M. A., & Sperry, J. (2020) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2020.115820 · Cited by 106 · see citing works

Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture

Chan, W. S., Durairajan, S. S. K., Lu, J., Wang, Y., Xie, L., Kum, W.-F., Koo, I., Yung, K. K. L., & Li, M. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.04.012 · Cited by 107 · see citing works

W ithania somnifera (Ashwagandha) in neurobehavioural disorders induced by brain oxidative stress in rodents: a systematic review and meta-analysis

Durg, S., Dhadde, S. B., Vandal, R., Shivakumar, B. S., & Charan, C. S. (2015) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12398 · Cited by 110 · see citing works

A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway Engineering

Dhar, N., Razdan, S., Rana, S., Bhat, W. W., Vishwakarma, R. A., & Lattoo, S. K. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.01031 · Cited by 102 · see citing works

Withanolides and Related Steroids

Misico, R. I., Nicotra, V. E., Oberti, J. C., Barboza, G. E., Gil, R. R., & Burton, G. (2011) · Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products · doi:10.1007/978-3-7091-0748-5_3 · Cited by 99 · see citing works

Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses

Widodo, N., Takagi, Y., Shrestha, B. G., Ishii, T., Kaul, S. C., & Wadhwa, R. (2008) · Cancer Letters · doi:10.1016/j.canlet.2007.11.037 · Cited by 96 · see citing works

Water Extract of Ashwagandha Leaves Has Anticancer Activity: Identification of an Active Component and Its Mechanism of Action

Wadhwa, R., Singh, R., Gao, R., Shah, N., Widodo, N., Nakamoto, T., Ishida, Y., Terao, K., & Kaul, S. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077189 · Cited by 90 · see citing works

The Role of Bioactive Compounds on the Promotion of Neurite Outgrowth

More, S. V., Koppula, S., Kim, I., Kumar, H., Kim, B.-W., & Choi, D. (2012) · Molecules · doi:10.3390/molecules17066728 · Cited by 89 · see citing works

Risk Assessment of Trigonelline in Coffee and Coffee By-Products

Konstantinidis, N., Franke, H., Schwarz, S., & Lachenmeier, D. W. (2023) · Molecules · doi:10.3390/molecules28083460 · Cited by 88 · see citing works

A Unified Approach for the Stereoselective Total Synthesis of Pyridone Alkaloids and Their Neuritogenic Activity

Jessen, H. J., Schumacher, A., Shaw, T. W., Pfaltz, A., & Gademann, K. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007671 · Cited by 87 · see citing works

A Potential Alternative against Neurodegenerative Diseases: Phytodrugs

Pérez‐Hernández, J., Zaldívar-Machorro, V. J., David, V.-P., Vega‐Avila, E., & Chavarría, A. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/8378613 · Cited by 86 · see citing works

Anti-neuroinflammation effect of ginsenoside Rbl in a rat model of Alzheimer disease

Wang, Y., Liu, J., Zhang, Z., Bi, P., Qi, Z., & Zhang, C. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.09.076 · Cited by 86 · see citing works

Hsp90/Cdc37 Chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A

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Trigonelline mitigates lipopolysaccharide-induced learning and memory impairment in the rat due to its anti-oxidative and anti-inflammatory effect

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Inflammatory responses bridge comorbid cardiac disorder in experimental model of IBD induced by DSS: protective effect of the trigonelline

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Withanolide A production from Withania somnifera hairy root cultures with improved growth by altering the concentrations of macro elements and nitrogen source in the medium

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Trigonelline-loaded chitosan nanoparticles prompted antitumor activity on glioma cells and biocompatibility with pheochromocytoma cells

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Neuroprotective and Antiapoptotic Potential of Trigonelline in a Striatal 6-Hydroxydopamine Rat Model of Parkinson’s Disease

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Development of New Therapies for Neurodegenerative Diseases via Axonal Growth

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New Age Therapy for Alzheimer’s Disease by Neuronal Network Reconstruction

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Aβ(25–35)-Induced Memory Impairment, Axonal Atrophy, and Synaptic Loss are Ameliorated by M1, A Metabolite of Protopanaxadiol-Type Saponins

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Axonal and Dendritic Extension by Protopanaxadiol-Type Saponins From Ginseng Drugs in SK-N-SH Cells

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