Bile Acids as Hormones: The FXR-FGF15/19 Pathway

Identification of a nuclear receptor for bile acids

Makishima, M., Okamoto, A. Y., Repa, J. J., Tu, H., Learned, R. M., Luk, A., Hull, M. V., Lustig, K. D., Mangelsdorf, D. J., & Shan, B. (1999) · Science · doi:10.1126/science.284.5418.1362 · Cited by 2,714

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

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Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

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Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR

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A G Protein-coupled Receptor Responsive to Bile Acids

Kawamata, Y., Fujii, R., Hosoya, M., Harada, M., Yoshida, H., Miwa, M., Fukusumi, S., Habata, Y., Itoh, T., Shintani, Y., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209706200 · Cited by 1,628

Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors

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Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

渡辺, 光., Houten, S. M., Wang, L., Moschetta, A., Mangelsdorf, D. J., Heyman, R. A., Moore, D. D., & Auwerx, J. H. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21025 · Cited by 1,425

Identification of a nuclear receptor that is activated by farnesol metabolites

Forman, B. M., Goode, E., Chen, J., Oro, A. E., Bradley, D. J., Perlmann, T., Noonan, D. J., Burka, L. T., McMorris, T., Lamph, W. W., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90530-8 · Cited by 1,210

Parenteral nutrition-associated liver injury: clinical relevance and mechanistic insights

Mihajlovic, M., Rosseel, Z., Waele, E. D., & Vinken, M. (2024) · Toxicological Sciences · doi:10.1093/toxsci/kfae020 · Cited by 23

Making Way for Suppressing the FGF19/FGFR4 Axis in Cancer

Prieto‐Domínguez, N., Shull, A. Y., & Teng, Y. (2018) · Future Medicinal Chemistry · doi:10.4155/fmc-2018-0099 · Cited by 21

Discovery of Orally Active and Nonsteroidal Farnesoid X Receptor (FXR) Antagonist with Propensity for Accumulation and Responsiveness in Ileum

Teno, N., Iguchi, Y., Oda, K., Yamashita, Y., Masuda, A., Fujimori, K., Une, M., & Gohda, K. (2021) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.0c00640 · Cited by 21

Hidden in the Fat: Unpacking the Metabolic Tango Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Syndrome

Boulos, M., Mousa, R. S., Jeries, N., Simaan, E., Alam, K., Bulus, B., & Assy, N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073448 · Cited by 22

Metabolic-Associated Fatty Liver Disease and Insulin Resistance: A Review of Complex Interlinks

Barber, T. M., Kabisch, S., Pfeiffer, A. F. H., & Weickert, M. O. (2023) · Metabolites · doi:10.3390/metabo13060757 · Cited by 22

Multiple therapeutic targets in rare cholestatic liver diseases: Time to redefine treatment strategies

Gerussi, A., D’Amato, D., Cristoferi, L., O’Donnell, S. E., Carbone, M., & Invernizzi, P. (2019) · Annals of Hepatology · doi:10.1016/j.aohep.2019.09.009 · Cited by 20

No Gut No Gain! Enteral Bile Acid Treatment Preserves Gut Growth but Not Parenteral Nutrition–Associated Liver Injury in a Novel Extensive Short Bowel Animal Model

Villalona, G. A., Price, A., Blomenkamp, K., Manithody, C., Saxena, S., Ratchford, T. L., Westrich, M., Kakarla, V., Pochampally, S., Phillips, W., et al. (2018) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1167 · Cited by 21

Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease

Hylemon, P. B., Su, L., Zheng, P., Bajaj, J. S., & Zhou, H. (2021) · Comprehensive physiology · doi:10.1002/cphy.c210024 · Cited by 29

Perfluoropolyether-Based Gut-Liver-on-a-Chip for the Evaluation of First-Pass Metabolism and Oral Bioavailability of Drugs

Wang, M., Sasaki, Y., Sakagami, R., Minamikawa, T., Tsuda, M., Ueno, R., Deguchi, S., Negoro, R., So, K., Higuchi, Y., et al. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c00605 · Cited by 20

IBAT inhibitors in pediatric cholestatic liver diseases: Transformation on the horizon?

Sutton, H., Sokol, R. J., & Kamath, B. M. (2024) · Hepatology · doi:10.1097/hep.0000000000001032 · Cited by 19

GPCR-mediated effects of fatty acids and bile acids on glucose homeostasis

Oteng, A., & Liu, L. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1206063 · Cited by 22

Farnesoid X receptor (FXR) activation induces the antioxidant protein metallothionein 1 expression in mouse liver

Wang, B., Zhang, H., Luan, Z., Xu, H., Wei, Y., Zhao, X., Xing, M., Huo, X., Zhang, J., Su, W., et al. (2020) · Experimental Cell Research · doi:10.1016/j.yexcr.2020.111949 · Cited by 18

Deletion of Intestinal SHP Impairs Short-term Response to Cholic Acid Challenge in Male Mice

Nguyen, J. T., Riessen, R., Zhang, T., Kieffer, C., & Anakk, S. (2021) · Endocrinology · doi:10.1210/endocr/bqab063 · Cited by 18

Apple Polyphenol Extracts Attenuated Depressive-Like Behaviors of High-Sucrose Diet Feeding Mice by Farnesoid X Receptor-Mediated Modulation of Bile Acid Circulation within the Liver–Gut–Brain Axis

Xie, Y., Shang, S., Luan, W., Ma, J., Yang, H., Qian, Q., Wu, Z., & Li, X. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c07035 · Cited by 18

Modulation of bile acids and farnesoid X receptor by dietary Polysaccharides: Critical roles in health and disease

Han, Y., Guo, X., Du, H., Guo, Y., Ding, Q., Li, F., Meng, Y., & Xiao, H. (2025) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2025.105075 · Cited by 20

Present and emerging pharmacotherapies for non-alcoholic steatohepatitis in adults

Ogawa, Y., Yoneda, M., Kobayashi, T., Honda, Y., Kessoku, T., Imajo, K., Saito, S., & Nakajima, A. (2018) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2018.1543403 · Cited by 18

Bile acids as novel enhancers of CNS targeting antitumor drugs: a comprehensive review

Gvoic, M., Vukmirović, S., Al‐Salami, H., Mooranian, A., Mikov, M., & Stankov, K. (2021) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2021.1916032 · Cited by 17

Bile Acid Supplementation Improves Murine Pancreatitis in Association With the Gut Microbiota

Wan, Y., Zhu, R., Pan, X., & Sun, T. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00650 · Cited by 17

What's eating you? An update on Giardia, the microbiome and the immune response

Singer, S. M., Angelova, V. V., DeLeon, H., & Miskovsky, E. (2020) · Current Opinion in Microbiology · doi:10.1016/j.mib.2020.09.006 · Cited by 17

Black bean protein concentrate ameliorates hepatic steatosis by decreasing lipogenesis and increasing fatty acid oxidation in rats fed a high fat-sucrose diet

Hernández-Velázquez, I., Sánchez‐Tapia, M., Ordáz‐Nava, G., Torres, N., Tovar, A. R., & Mariscal, A. G. (2020) · Food & Function · doi:10.1039/d0fo02258f · Cited by 17

Interaction between gut-heart axis in sepsis-induced cardiomyopathy

Zhou, Z.-K., Yu, M., Shou, S., Chai, Y., & Liu, Y. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107806 · Cited by 18

Biological functions and pharmacological behaviors of bile acids in metabolic diseases

Zhuang, T., Wang, X., Wang, Z., Gu, L., Yue, D., Wang, Z., Li, X., Yang, L., Huang, W., & Ding, L. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.11.003 · Cited by 23

Bacillus amyloliquefaciens TL Downregulates the Ileal Expression of Genes Involved in Immune Responses in Broiler Chickens to Improve Growth Performance

Hong, Y., Yang, C. X., Guan, L. L., Zhou, Z., Li, X., Shi, D., & Xiao, Y. (2021) · Microorganisms · doi:10.3390/microorganisms9020382 · Cited by 17

Duodenal-jejunal lining increases postprandial unconjugated bile acid responses and disrupts the bile acid-FXR-FGF19 axis in humans

van Nierop, F. S., de Jonge, C., Kulik, W., Bouvy, N. D., Schaap, F. G., Damink, S. W. M. O., Rensen, S. S., Romijn, J. A., Greve, J. W. M., & Soeters, M. R. (2019) · Metabolism · doi:10.1016/j.metabol.2018.12.009 · Cited by 17

FXR overexpression alleviates cholestasis via NLRC4 inflammasome suppression and bile acid homeostasis regulation.

Wang, W., Li, L., Li, X., Chen, J.-Q., Wang, R., Yang, Q., Qu, Y.-F., Wang, C.-Y., Fu, T., & Meng, Q. (2025) · Free Radical Biology & Medicine · doi:10.1016/j.freeradbiomed.2025.06.039 · Cited by 13

Bile acids in liver and gastrointestinal cancer

Monte, M. J., Fàbrega, L., Romero, M. R., Temprano, Á. G., Kaplowitz, N., García‐Ruiz, C., Marı́n, J. J. G., & Fernández-Checa, J. C. (2025) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2025.09.002 · Cited by 16

FXR-targeted drug discovery: Recent advances and therapeutic perspectives

Li, Q., Liu, Z., Shang, W., Zhou, X., Mao, W., Cao, Y., & Shan, L. (2025) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2025.118332 · Cited by 19

Protective Mechanism of Eurotium amstelodami from Fuzhuan Brick Tea against Colitis and Gut-Derived Liver Injury Induced by Dextran Sulfate Sodium in C57BL/6 Mice

Wang, X., Liu, J., Wei, J., Zhang, Y., Xu, Y., Yue, T., & Yuan, Y. (2024) · Nutrients · doi:10.3390/nu16081178 · Cited by 15

Association of serum fibroblast growth factor 19 levels with arteriosclerosis parameters assessed by arterial stiffness and atherogenic index of plasma in patients with type 2 diabetes

Liu, W., Tang, M., Xu, T., Su, J., Wang, X., Xu, F., Zhang, D., Zhu, Q. X., Cao, J. J., & Wang, H. (2020) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-020-00552-0 · Cited by 15

Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC–MS/MS in Humans, Mice, and Pigs—A Qualitative Analysis

Babu, A. F., Koistinen, V., Turunen, S., Solano-Aguilar, G. I., Urban, J. F., Zarei, I., & Hanhineva, K. (2022) · Metabolites · doi:10.3390/metabo12010049 · Cited by 15

Smooth muscle cells, interstitial cells and neurons in the gallbladder (GB): Functional syncytium of electrical rhythmicity and GB motility (Review)

Ding, F., Hu, Q., Wang, Y., Jiang, M., Cui, Z.-Y., Guo, R., Liu, L., Chen, F., HU, H. X., & Zhao, G. (2023) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2023.5236 · Cited by 17

Emerging drugs for the treatment of non-alcoholic steatohepatitis: a focused review of farnesoid X receptor agonists

Shah, R. A., Alkhouri, N., & Kowdley, K. V. (2020) · Expert Opinion on Emerging Drugs · doi:10.1080/14728214.2020.1796968 · Cited by 15

Gut microbiome and bile acid metabolism in liver disease: Mechanisms, clinical implications, and therapeutic opportunities

Zhou, H., Huang, Y., Chen, C., Song, M., & Hylemon, P. B. (2026) · Pharmacological Reviews · doi:10.1016/j.pharmr.2026.100120 · Cited by 17

Regulation of Energy Homeostasis After Gastric Bypass Surgery

Yarmush, M. L., D'Alessandro, M. R., & Saeidi, N. (2017) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071813-105140 · Cited by 14

Bile Acids as a New Type of Steroid Hormones Regulating Nonspecific Energy Expenditure of the Body (Review)

Загоскин, П. П., & Erlykina, E. I. (2020) · Современные технологии в медицине · doi:10.17691/stm2020.12.5.13 · Cited by 16

Western Diet Aggravated Carbon Tetrachloride‐Induced Chronic Liver Injury by Disturbing Gut Microbiota and Bile Acid Metabolism

Yang, L., Li, Y., Wang, S., Bian, X., Jiang, X., Wu, J., Wang, K., Wang, Q., Xia, J., Jiang, S., et al. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000811 · Cited by 14

Cholesterol-lowering effects of taurine through the reduction of ileal FXR signaling due to the alteration of ileal bile acid composition

Miyata, M., Tanaka, T., Takahashi, K., Funaki, A., & Sugiura, Y. (2021) · Amino Acids · doi:10.1007/s00726-021-03068-7 · Cited by 14

Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer

Tang, Q., & Evans, R. M. (2021) · Essays in Biochemistry · doi:10.1042/ebc20210038 · Cited by 14

New advances in novel pharmacotherapeutic candidates for the treatment of metabolic dysfunction-associated steatohepatitis (MASH) between 2022 and 2024

Wong, S. W., Yang, Y., Chen, H., Xie, L. H., Shen, X., Zhang, N., & Wu, J. H. (2025) · Acta Pharmacologica Sinica · doi:10.1038/s41401-024-01466-7 · Cited by 14

Clinical management of autoimmune liver diseases: juncture, opportunities, and challenges ahead

Chen, Y., Chen, R., Li, H., & Shuai, Z. (2025) · Immunologic Research · doi:10.1007/s12026-025-09622-9 · Cited by 14

The Microbial Bile Acid Metabolite 3-Oxo-LCA Inhibits Colorectal Cancer Progression

Sun, F., Wang, K., Dong, X., Secaira-Morocho, H., Hui, A., Cai, C., Sze, J., Low, B., Udgata, S., Pasch, C. A., et al. (2025) · Cancer Research · doi:10.1158/0008-5472.can-24-3898 · Cited by 17

Implications of the Liver-Gut Axis in Liver Disease: From Mechanisms to Therapeutic Targets

Ramírez-Mejía, M. M., Ponciano‐Rodríguez, G., & Méndez‐Sánchez, N. (2025) · Archives of Medical Research · doi:10.1016/j.arcmed.2025.103335 · Cited by 15

Salt and Gut Microbiota in Heart Failure

Masenga, S. K., & Kirabo, A. (2023) · Current Hypertension Reports · doi:10.1007/s11906-023-01245-5 · Cited by 13

Dysbiosis of gut microbiota after cholecystectomy is associated with non‐alcoholic fatty liver disease in mice

Wang, Q., Lu, Q.-F., Shao, W.-T., Jiang, Z.-Y., & Hu, H. (2021) · FEBS Open Bio · doi:10.1002/2211-5463.13243 · Cited by 12

Gender and gut microbiota composition determine hepatic bile acid, metabolic and inflammatory response to a single fast-food meal in healthy adults

Figge, A., Sydor, S., Wenning, C., Manka, P. P., Aßmuth, S., Vilchez‐Vargas, R., Link, A., Jähnert, A., Brodesser, S., Lucas, C., et al. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.04.008 · Cited by 14

Evaluation of FGF-19 and β-klotho as biomarkers in patients with intrahepatic cholestasis of pregnancy

Tayyar, A. T., Tayyar, A., Kozalı, Ş., Karakuş, R., Köroğlu, N., Yüksel, İ. T., Yıldırım, G. Y., Dağ, İ., & Eroğlu, M. (2018) · Archives of Medical Science · doi:10.5114/aoms.2017.72424 · Cited by 13

Pediatric metabolic dysfunction–associated steatotic liver disease and the gut microbiome: from research landscape to targeted modulation

Jiang, L., Du, L.-D., Zeng, J., Chu, H., Peng, Z., & Fan, J. (2025) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2025.0718 · Cited by 12

FXR crosstalk with other nuclear receptors

Mohammed, T. A., & Zalzala, M. H. (2025) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-025-01118-2 · Cited by 14

The Therapeutic Role of Xenobiotic Nuclear Receptors Against Metabolic Syndrome

Pu, S., Wu, X., Yang, X., Zhang, Y., Dai, Y., Zhang, Y., Wu, X., Liu, Y., Cui, X., Jin, H., et al. (2018) · Current Drug Metabolism · doi:10.2174/1389200219666180611083155 · Cited by 12

Association of FGF19, FGF21 and FGF23 with carbohydrate metabolism parameters and insulin resistance in patients with chronic kidney disease

Marchelek‐Myśliwiec, M., Dziedziejko, V., Dołęgowska, K., Pawlik, A., Safranow, K., Stępniewska, J., Wiśniewska, M., Małyszko, J., & Ciechanowski, K. (2020) · Journal of Applied Biomedicine · doi:10.32725/jab.2020.005 · Cited by 12

Bile Acid Receptor Farnesoid X Receptor: A Novel Therapeutic Target for Metabolic Diseases

Fang, S. (2017) · Journal of Lipid and Atherosclerosis · doi:10.12997/jla.2017.6.1.1 · Cited by 12

Developmental regulation of the intestinal FGF19 system in domestic pigs

Gavaldà‐Navarro, A., Pastor, J. J., Mereu, A., Villarroya, F., & Ipharraguerre, I. R. (2018) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00312.2017 · Cited by 12

Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation

Weber, A. A., Mennillo, E., Yang, X., van der Schoor, L. W. E., Jonker, J. W., Chen, S., & Tukey, R. H. (2020) · Drug Metabolism and Disposition · doi:10.1124/dmd.120.000240 · Cited by 12

Determination of Bile Acids in Canine Biological Samples: Diagnostic Significance

Németh, K., Sterczer, Á., Kiss, D. S., Lányi, R. K., Hemző, V., Vámos, K., Bartha, T., Buzás, A., & Lányi, K. (2024) · Metabolites · doi:10.3390/metabo14040178 · Cited by 12

Lactobacillus johnsonii CCFM1376 improves hypercholesterolemia in mice by regulating the composition of bile acids

Chen, K., Dang, D., Li, H., Ross, R. P., Stanton, C., Chen, W., & Yang, B. K. (2024) · Microbiome Research Reports · doi:10.20517/mrr.2024.38 · Cited by 13

Endocrine pheromones couple fat rationing to dauer diapause through HNF4α nuclear receptors

Gao, C., Li, Q., Yu, J., Li, S., Cui, Q., Hu, X., Chen, L., & Zhang, S. O. (2021) · Science China Life Sciences · doi:10.1007/s11427-021-2016-9 · Cited by 11

Non-invasive evaluation of NAFLD and the contribution of genes: an MRI-PDFF-based cross-sectional study

Yang, A., Zhu, X., Zhang, L., Zhang, Y., Zhang, D., Jin, M., Niu, J., Zhang, H., Ding, Y., & Lv, G. (2022) · Hepatology International · doi:10.1007/s12072-022-10355-2 · Cited by 11

Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease

Kim, Y., Qi, M., Dong, X., Seok, S., Sun, H., KEMPER, B. W., Fu, T., & Kemper, J. K. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104946 · Cited by 11

Endocrine FGFs and their signaling in the brain: Relevance for energy homeostasis

Zangerolamo, L., Carvalho, M. U. W. B. D., Velloso, L. A., & Barbosa, H. C. L. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176248 · Cited by 11

Molecular regulators of lipid metabolism in the intestine – Underestimated therapeutic targets for obesity?

Dávalos-Salas, M., Mariadason, J. M., Watt, M. J., & Montgomery, M. K. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114091 · Cited by 11

Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

Kozuka, C., Efthymiou, V., Sales, V., Zhou, L., Osataphan, S. A., Yuchi, Y., CHIMENE-WEISS, J. I., Mulla, C. M., ISGANAITIS, E. M., Desmond, J., et al. (2022) · Diabetes · doi:10.2337/db21-0574 · Cited by 11

Lysine tRNA fragments and miR-194-5p co-regulate hepatic steatosis via β-Klotho and perilipin 2

Tzur, Y., Winek, K., Madrer, N., Dubnov, S., Bennett, E. R., Greenberg, D., Hanin, G., Gammal, A., Tam, J., Arkin, I. T., et al. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101856 · Cited by 10

New advances in drug development for metabolic dysfunction-associated diseases and alcohol-associated liver disease

Zhang, J., Li, Y., Liu, Y., Ma, N., Qian, S., Chen, Y., Duan, Y., Xiang, X., & He, Y. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01267-9 · Cited by 10

A Narrative Review: Immunometabolic Interactions of Host–Gut Microbiota and Botanical Active Ingredients in Gastrointestinal Cancers

Li, S., Feng, W., Wu, J., Cui, H., Wang, Y., Liang, T., An, J., Chen, W., Guo, Z., & Lei, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25169096 · Cited by 10

Farnesoid X Receptor Regulated Sepsis‐Induced Abnormal Bile Acid Metabolism via the Fibroblast Growth Factor 15/Fibroblast Growth Factor Receptor 4 Pathway

Zhou, Z., Xu, D., Huang, L., Cui, Y., Chen, H., & Tang, J. (2025) · Immunity Inflammation and Disease · doi:10.1002/iid3.70155 · Cited by 10

Bile Acids in Control of the Gut-Liver-Axis

Hild, B., Heinzow, H. S., Schmidt, H., & Maschmeier, M. (2021) · Zeitschrift für Gastroenterologie · doi:10.1055/a-1330-9644 · Cited by 10

The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis

Liu, S.-M., Ifebi, B., Johnson, F., Xu, A., Ho, J., Yang, Y., Schwartz, G. J., Jo, Y., & Chua, S. C. (2023) · Journal of Clinical Investigation · doi:10.1172/jci164185 · Cited by 10

Skin advanced glycation end-products as indicators of the metabolic profile in diabetes mellitus: correlations with glycemic control, liver phenotypes and metabolic biomarkers

Christidis, G., Küppers, F., Karataylı, S. C., Karataylı, E., Weber, S. N., Lammert, F., & Krawczyk, M. J. (2024) · BMC Endocrine Disorders · doi:10.1186/s12902-024-01558-9 · Cited by 10

Gut dysbiosis impairs intestinal renewal and lipid absorption in Scarb2 deficiency-associated neurodegeneration

Li, Y., Liu, X., Sun, X., Li, H., Wang, S., Tian, W., Chen, X., Zhang, X., Zheng, J., Wang, H., et al. (2024) · Protein & Cell · doi:10.1093/procel/pwae016 · Cited by 10

Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.

Miyata, M., Shinno, K., Kinoshita, T., Kinoshita, Y., & Sugiura, Y. (2017) · Journal of Toxicological Sciences · doi:10.2131/jts.42.671 · Cited by 9

A Villin-Driven Fxr Transgene Modulates Enterohepatic Bile Acid Homeostasis and Response to an n-6-Enriched High-Fat Diet

Wren, S. N., Donovan, M. G., Selmin, O. I., Doetschman, T. C., & Romagnolo, D. F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21217829 · Cited by 10

New insights into the regulation of bile acids synthesis during the early stages of liver regeneration: A human and experimental study

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Simiao Wan attenuates high-fat diet-induced hyperlipidemia in mice by modulating the gut microbiota–bile acid axis

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