High-Intensity Interval Training to Maximize Cardiac Benefits of Exercise Training?
Abstract
In Brief We hypothesized that high-intensity aerobic interval training results in a greater beneficial adaptation of the heart compared with that observed after low-to-moderate exercise intensity. This is supported by recent epidemiological, experimental, and clinical studies. Cellular and molecular mechanisms of myocardial adaptation to exercise training are discussed in this review. Health effects of exercise-induced cellular and molecular cardiovascular adaptation mechanisms are markedly larger in interval training at high relative intensity.
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HIIT promotes cardiometabolic adaptations that are often superior to moderate-intensity continuous training (MICT) across a range of clinical populations.
“HIIT has garnered attention in recent years because it promotes cardiometabolic adaptations that are often superior to moderate-intensity continuous training (MICT) across a range of clinical populations [10, 11].”
From High-Intensity Interval Training as an Efficacious Alternative to Moderate-Intensity Continuous Training for Adults with Prediabetes (2015) · cites this paper as [10]
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- Authors
- Wisløff, U., Ellingsen, Ø., & Kemi, O. J.
- Affiliations
- Norwegian University of Science and Technology (NO)
- University of Glasgow (GB)
- Corresponding author
- Wisløff, Ulrik
- Venue
- Exercise and Sport Sciences Reviews
- Published
- 2009-07
- Volume
- 37
- Issue
- 3
- Pages
- 139-146
- ISSN
- 0091-6331 (ISSN-L)
- OpenAlex
- W2067589291
- Cited by
- 330
- References
- 36
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 15 · 2023: 18 · 2022: 15 · 2021: 19 · 2020: 25 · 2019: 31 · 2018: 23 · 2017: 30 · 2016: 22 · 2015: 24 · 2014: 24 · 2013: 23 · 2012: 16
- FWCI
- 2.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Exercise and Sport Sciences Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- St. Olavs Hospital Universitetssykehuset i Trondheim
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- high-intensity interval training, aerobic exercise training, cardiac adaptation, myocardial adaptation, exercise intensity, cardiovascular health, cellular and molecular mechanisms, cardioprotection
- MeSH terms
- Adaptation, Physiological, Animals, Cardiovascular Diseases, Heart, Humans, Sports, Exercise
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