The DOI matches its Crossref record, with a small difference in title or year; 129 of the 129 references it cites were found in a registry or an index.
Depression as a Risk Factor for Poor Prognosis Among Patients With Acute Coronary Syndrome: Systematic Review and Recommendations: A Scientific Statement From the American Heart Association
Open accessAbstract
Background—: Although prospective studies, systematic reviews, and meta-analyses have documented an association between depression and increased morbidity and mortality in a variety of cardiac populations, depression has not yet achieved formal recognition as a risk factor for poor prognosis in patients with acute coronary syndrome by the American Heart Association and other health organizations. The purpose of this scientific statement is to review available evidence and recommend whether depression should be elevated to the status of a risk factor for patients with acute coronary syndrome. Methods and Results—: Writing group members were approved by the American Heart Association’s Scientific Statement and Manuscript Oversight Committees. A systematic literature review on depression and adverse medical outcomes after acute coronary syndrome was conducted that included all-cause mortality, cardiac mortality, and composite outcomes for mortality and nonfatal events. The review assessed the strength, consistency, independence, and generalizability of the published studies. A total of 53 individual studies (32 reported on associations with all-cause mortality, 12 on cardiac mortality, and 22 on composite outcomes) and 4 meta-analyses met inclusion criteria. There was heterogeneity across studies in terms of the demographic composition of study samples, definition and measurement of depression, length of follow-up, and covariates included in the multivariable models. Despite limitations in some individual studies, our review identified generally consistent associations between depression and adverse outcomes. Conclusions—: Despite the heterogeneity of published studies included in this review, the preponderance of evidence supports the recommendation that the American Heart Association should elevate depression to the status of a risk factor for adverse medical outcomes in patients with acute coronary syndrome.
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“Elevated depressive and anxiety symptoms increase the risk for recurrent cardiac events and mortality after ACS [2].”
From Lower distress tolerance is associated with greater anxiety and depression symptoms among patients after acute coronary syndrome (2021) · cites this paper as [2]
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“One in five patients with ischaemic heart disease (IHD) develop comorbid depression or anxiety.”
From Efficacy and cost-effectiveness of a therapist-assisted web-based intervention for depression and anxiety in patients with ischemic heart disease attending cardiac rehabilitation [eMindYourHeart trial]: a randomised controlled trial protocol (2021) · cites this paper as [3]
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Citations
Cites
The environment and disease: association or causation?
Hill, A. B. (2015) · Journal of the Royal Society of Medicine · doi:10.1177/0141076814562718 · Cited by 7,804
The Environment and Disease: Association or Causation?
Hill, A. B. (1965) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591576505800503 · Cited by 6,974
Pearlin, L. I., Menaghan, E. G., Lieberman, M. A., & Mullan, J. T. (1981) · Journal of Health and Social Behavior · doi:10.2307/2136676 · Cited by 6,289
Heart Disease and Stroke Statistics—2014 Update
Go, A. S., Mozaffarian, D., Roger, V. L., Benjamin, E. J., Berry, J. D., Blaha, M. J., Dai, S., Ford, E. S., Fox, C. S., Franco, S., et al. (2013) · Circulation · doi:10.1161/01.cir.0000441139.02102.80 · Cited by 5,264
Self-citationDepression Following Myocardial Infarction
Frasure‐Smith, N. (1993) · JAMA · doi:10.1001/jama.1993.03510150053029 · Cited by 2,039
Self-citation(2003) · JAMA · doi:10.1001/jama.289.23.3106 · Cited by 1,870
Self-citationSmith, S. C., Benjamin, E. J., Bonow, R. O., Braun, L. T., Creager, M. A., Franklin, B. A., Gibbons, R. J., Grundy, S. M., Hiratzka, L. F., Jones, D. W., et al. (2011) · Circulation · doi:10.1161/cir.0b013e318235eb4d · Cited by 1,759
Depression and 18-Month Prognosis After Myocardial Infarction
Frasure‐Smith, N., Lespérance, F., & Talajic, M. R. (1995) · Circulation · doi:10.1161/01.cir.91.4.999 · Cited by 1,546
Self-citationLichtman, J. H., Bigger, J. T., Blumenthal, J. A., Frasure-Smith, N., Kaufmann, P. G., Lespérance, F., Mark, D. B., Sheps, D. S., Taylor, C. B., & Froelicher, E. S. (2008) · Circulation · doi:10.1161/circulationaha.108.190769 · Cited by 1,482
Self-citationComing to terms with the terms of risk
Kraemer, H. C. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830160065009 · Cited by 1,432
Research works printed but not linked: 4
- 10.1097/00006842-200405000-00004 · DOI
- Centers for Disease Control and Prevention. Current depression among adults: United States, 2006 and 2008 [published correction appears in MMWR Morb Mortal Wkly Rep. 2011;60:518]. MMWR Morb Mortal Wkly Rep. 2010;59:1229–1235.
- 10.1037/0278-6133.14.5.388 · DOI
- 10.1176/ajp.2006.163.7.1295a · DOI
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Crawshaw, J., Auyeung, V., Norton, S., & Weinman, J. (2016) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2016.09.003 · Cited by 97
Papasavvas, T., Bonow, R. O., Alhashemi, M., & Micklewright, D. P. (2015) · Sports Medicine · doi:10.1007/s40279-015-0409-5 · Cited by 86
“Furthermore, comorbid depression is associated with a poor prognosis of the underlying disease, such as DM [6] or heart failure [7], while also increasing the mortality risk after myocardial infarction [8].”
BackgroundGraham, N., Ward, J., Mackay, D., Pell, J. P., Cavanagh, J., Padmanabhan, S., & Smıth, D. J. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-024433 · Cited by 84
“admission CVD, as previous studies show depression may result from CVD(45) 46 and worsen prognosis.(46)”
MethodPersistent psychological distress and mortality in patients with stable coronary artery disease
Stewart, R., Colquhoun, D. M., Marschner, S. L., Kirby, A. C., Simes, J. R., Nestel, P. J., Glozier, N., O'Neil, A. E., Oldenburg, B. F., White, H. D., et al. (2017) · Heart · doi:10.1136/heartjnl-2016-311097 · Cited by 83
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Allgulander, C. (2015) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000217 · Cited by 81
Pederson, J. L., Warkentin, L. M., Majumdar, S. R., & McAlister, F. A. (2016) · Journal of Hospital Medicine · doi:10.1002/jhm.2547 · Cited by 81
“Some studies have suggested that depression is associated with metabolic abnormalities, including alterations in glucose transport(42,48) and increased vulnerability to obesity, type 2 diabetes mellitus, and/ or diabetic complications, common conditions among hospitalized patients that also adversely affect postdischa…”
BackgroundYoung, Q., Nguyen, M., Roth, S., Broadberry, A., & Mackay, M. (2014) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515114548649 · Cited by 79
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Polityńska, B., Pokorska, O., Wojtukiewicz, A. M., Sawicka, M., Mysliwiec, M., Honn, K. V., Tucker, S. C., & Wojtukiewicz, M. Z. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108293 · Cited by 83
May, H. T., Horne, B. D., Knight, S., Knowlton, K. U., Bair, T. L., LAPPE, D. L., Le, V. T., & Muhlestein, J. B. (2017) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcx017 · Cited by 79
Daniel, M., Agewall, S., Berglund, F., Caidahl, K., Collste, O., Ekenbäck, C., Frick, M., Henareh, L., Jernberg, T., Malmqvist, K. K., et al. (2018) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.04.040 · Cited by 78
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Teply, R. M., Packard, K. A., White, N. D., Hilleman, D. E., & DiNicolantonio, J. J. (2015) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2015.11.003 · Cited by 78
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“Although not currently listed among the conventional risk factors for heart disease, a recent scientific statement by the AHA recommends that depression should be elevated to risk factor status in patients with ACS because of its profound impact on prognosis.(100) This statement closely followed an earlier AHA Science…”
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Huang, M., Shah, A. J., Su, S., Goldberg, J. H., Lampert, R. J., Levantsevych, O. M., Shallenberger, L. H., Pimple, P. M., Bremner, J. D., & Vaccarino, V. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.0747 · Cited by 76
Self-citationOlsen, S. J., Schirmer, H., Wilsgaard, T., Bønaa, K. H., & Hanssen, T. A. (2018) · European Journal of Preventive Cardiology · doi:10.1177/2047487318778088 · Cited by 72
Barlinn, K., Kepplinger, J., Puetz, V., Illigens, B., Bodechtel, U., & Siepmann, T. (2014) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s63904 · Cited by 72
“According to our formulated PICOS (participants, interventions, comparators, outcomes, and study design) question, 12 an original epidemiological study was included if 1) participants were nonhospitalized adults with no history of stroke or transient ischemic attack (TIA) at the time of study initiation, 2) the exposu…”
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Xu, L., Zhai, X., Shi, D., & Zhang, Y. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1328048 · Cited by 86
Gokhale, R. H., Weiser, J. K., Sullivan, P. S., Luo, Q., Shu, F., & Bradley, H. M. (2019) · AIDS and Behavior · doi:10.1007/s10461-019-02613-6 · Cited by 71
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Millstein, R. A., Celano, C. M., Beale, E. E., Beach, S. R., Suarez, L. S. K., Belcher, A. M., Januzzi, J. L., & Huffman, J. C. (2016) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2016.08.006 · Cited by 70
Shivappa, N., Hébert, J. R., Veronese, N., Caruso, M. G., Notarnicola, M., Maggi, S., Stubbs, B., Firth, J., Fornaro, M., & Solmi, M. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.014 · Cited by 75
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Huang, M., Su, S., Goldberg, J. H., Miller, A. H., Levantsevych, O. M., Shallenberger, L. H., Pimple, P. M., Pearce, B. D., Bremner, J. D., & Vaccarino, V. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.10.007 · Cited by 66
Self-citationSki, C. F., Taylor, R. S., McGuigan, K., Long, L., Lambert, J. D., Richards, S. H., & Thompson, D. R. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013508.pub3 · Cited by 85
Gauci, S., Cartledge, S. H., Redfern, J., Gallagher, R. D., Huxley, R., Lee, C., Vassallo, A. J., & O'Neil, A. E. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01046-2 · Cited by 71
Sobolewska-Nowak, J., Wachowska, K., Nowak, A., Orzechowska, A., Szulc, A., Płaza, O., & Gałecki, P. (2023) · Biomedicines · doi:10.3390/biomedicines11071903 · Cited by 72
“In March 2014, the AHA recommended elevating depression to a risk factor for adverse outcomes in patients with acute coronary syndrome [26].”
BackgroundBDNFVal66met polymorphism: a potential bridge between depression and thrombosis
Amadio, P., Colombo, G. I., Tarantino, E., Gianellini, S., Ieraci, A., Brioschi, M., Banfi, C., Werba, J. P., Parolari, A., Lee, F. S., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv655 · Cited by 68
“A recent review suggests that depression should be included among the risk factors (RFs) for adverse medical outcomes in patients with ACS.(1) The depressive status, resulting in an increased prevalence of cardiovascular RFs and in potential non-adherence to secondary prevention measures, is associated with an unhealt…”
BackgroundCelano, C. M., Albanese, A. M., Millstein, R. A., Mastromauro, C. A., Chung, W.-J., Campbell, K. A., Legler, S. R., Park, E. R., Healy, B. C., Collins, L. M., et al. (2018) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000584 · Cited by 78
Wright, C. D., Tiani, A. G., Billingsley, A. L., Steinman, S. A., Larkin, K. T., & McNeil, D. W. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02498 · Cited by 76
Fernandes, N., Prada, L., Rosa, M. M., Ferreira, J. J., Costa, J. N., Pinto, F. J., & Caldeira, D. (2020) · Clinical Research in Cardiology · doi:10.1007/s00392-020-01697-8 · Cited by 69
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Jackson, J. L., Leslie, C. E., & Hondorp, S. N. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.07.015 · Cited by 67
Selected psychological comorbidities in coronary heart disease: Challenges and grand opportunities.
Davidson, K. W., Alcántara, C., & Miller, G. E. (2018) · American Psychologist · doi:10.1037/amp0000239 · Cited by 68
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Tully, P. J., Ang, S. Y., Lee, E. J., Bendig, E., Bauereiß, N., Bengel, J., & Baumeister, H. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008012.pub4 · Cited by 71
Bipolar Disorder and the Vascular System: Mechanisms and New Prevention Opportunities
Goldstein, B. I. (2017) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2017.10.006 · Cited by 65
Depression and increased risk of non-alcoholic fatty liver disease in individuals with obesity
Cho, I. Y., Chang, Y., Sung, E., Kang, J., Wild, S. H., Byrne, C. D., Shin, H. C., & Ryu, S. (2021) · Epidemiology and Psychiatric Sciences · doi:10.1017/s204579602000116x · Cited by 63
“All of these comorbidities are also commonly accompanied by NAFLD (Luppino et al., 2010; Dong et al., 2012; Cuijpers et al., 2014; Lichtman et al., 2014).”
BackgroundCoronary Heart Disease and Depression or Anxiety: A Bibliometric Analysis
Zhou, Y., Zhu, X., Shi, J., Yuan, G., Yao, Z.-A., Chu, Y., Shi, S., Jia, Q., Chen, T., & Hu, Y. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.669000 · Cited by 66
“Psychometric properties of instruments for assessing depression and anxiety in patients with CHD In as early as 2004, researchers investigated the psychometric properties of the Hospital Anxiety and Depression Scale (HADS) as a screening instrument for patients with ACS and confirmed that the HADS was useful in assess…”
BackgroundInfluentialWillis, B. L., Leonard, D., Barlow, C. E., Martin, S. B., DeFina, L. F., & Trivedi, M. H. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.1467 · Cited by 62
Kupper, N. H. M., & Denollet, J. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.09.006 · Cited by 63
Jóźwik, S., Cieślik, B., Gajda, R., & Szczepańska-Gieracha, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10102148 · Cited by 60
“Keywords: cardiovascular disease; CVD; depression; anxiety; cardiac rehabilitation; virtual reality”
BackgroundInfluentialOptimism and Recovery After Acute Coronary Syndrome
Ronaldson, A., Molloy, G. J., Wikman, A., Poole, L., Kaski, J. C., & Steptoe, A. (2015) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000155 · Cited by 63
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BackgroundKronish, I. M., Moise, N., Cheung, Y. K., Clarke, G. N., Dolor, R. J., Duer-Hefele, J., Margolis, K. L., St Onge, T., Parsons, F., Retuerto, J., et al. (2020) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2019.4518 · Cited by 62
Drudi, L. M., Ades, M., Turkdogan, S., Huynh, C., Lauck, S., Webb, J. G., Piazza, N., Martucci, G. J., Langlois, Y., Perrault, L. P., et al. (2018) · JAMA Cardiology · doi:10.1001/jamacardio.2017.5064 · Cited by 58
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Vance, M. C., Wiitala, W. L., Sussman, J. B., Pfeiffer, P., & Hayward, R. A. (2019) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.119.005563 · Cited by 57
Nijjar, P. S., Connett, J. E., Lindquist, R. A., Brown, R. Z., Burt, M. A., Pergolski, A., Wolfe, A. G., Balaji, P., Chandiramani, N. V., Yu, X., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-54932-2 · Cited by 57
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Andonian, C., Beckmann, J., Biber, S., Ewert, P., Freilinger, S., Kaemmerer, H. M., Oberhoffer, R., Pieper, L., & Neidenbach, R. C. (2018) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt.2018.12.06 · Cited by 57
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BackgroundCardiovascular Care in Women Veterans
Han, J. K., Yano, E. M., Watson, K. E., & Ebrahimi, R. (2019) · Circulation · doi:10.1161/circulationaha.118.037748 · Cited by 57
Wang, Q., Chair, S. Y., & Wong, E. M. L. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.12.084 · Cited by 56
Fenger‐Grøn, M., Vestergaard, M., Pedersen, H. S., Frost, L., Parner, E. T., Ribe, A. R., & Davydow, D. S. (2018) · European Journal of Preventive Cardiology · doi:10.1177/2047487318811184 · Cited by 55
Anxiety and prognosis of patients with myocardial infarction: A meta‐analysis
Wen, Y., Yang, Y., Shen, J., & Luo, S.-X. (2021) · Clinical Cardiology · doi:10.1002/clc.23605 · Cited by 49
Bunevičienė, I., Bunevičius, R., Bagdonas, Š., & Bunevičius, A. (2021) · Journal of Public Health · doi:10.1093/pubmed/fdab248 · Cited by 57
Uhlenbusch, N., Swaydan, J., Höller, A., Löwe, B., & Depping, M. K. (2021) · Psychological Medicine · doi:10.1017/s0033291721003792 · Cited by 58
Pinter, A., Szatmari Jr, S., Horvath, T., Penzlin, A. I., Barlinn, K., Siepmann, M., & Siepmann, T. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s200360 · Cited by 53
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BackgroundRoberge, P., Hudon, C., Pavilanis, A., Beaulieu, M., Benoît, A., Brouillet, H., Boulianne, I., Pauw, A. D., Frigon, S., Gaboury, I., et al. (2016) · BMC Family Practice · doi:10.1186/s12875-016-0531-y · Cited by 75
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Albus, C., Waller, C. F., Fritzsche, K., Gunold, H., Haass, M., Hamann, B., Kindermann, I., Köllner, V., Leithäuser, B., Marx, N., et al. (2018) · Der Kardiologe · doi:10.1007/s12181-018-0271-4 · Cited by 53
Murri, M. B., Folesani, F., Zerbinati, L., Nanni, M. G., Ounalli, H., Caruso, R., & Grassi, L. G. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17155545 · Cited by 58
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BackgroundKarlsen, H. R., Matejschek, F., Saksvik‐Lehouillier, I., & Langvik, E. (2021) · Health Psychology Open · doi:10.1177/2055102920987462 · Cited by 53
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BackgroundResultAnxiety and clinical outcomes of patients with acute coronary syndrome: a meta-analysis
Li, J., Ji, F., Song, J., Gao, X., Jiang, D., Chen, G., Chen, S., Lin, X., & Zhuo, C. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-034135 · Cited by 61
Chen, Y., Cui, P. Y., Pan, Y., Waili, N., Waili, N., & Li, Y. (2021) · BMC Geriatrics · doi:10.1186/s12877-021-02207-9 · Cited by 52
Achttien, R. J., van Lieshout, J., Wensing, M., der Sanden, M. W. G. N., & Staal, J. B. (2019) · BMC Cardiovascular Disorders · doi:10.1186/s12872-019-1065-8 · Cited by 59
Anxiety and Depression in Adults With Congenital Heart Disease
Kovacs, A. H., Luyckx, K., Thomet, C., Budts, W., Enomoto, J., Sluman, M. A., Lu, C., Jackson, J. L., Khairy, P., Cook, S. C., et al. (2024) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.10.043 · Cited by 51
Palacios, J. E., Khondoker, M. R., Achilla, E., Tylee, A. T., & Hotopf, M. H. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158163 · Cited by 51
“It is both a causal factor [3,4] and poor prognostic indicator [5], being associated with a range of adverse outcomes, including mortality [6,7], but mechanisms for such associations are incompletely understood [8].”
BackgroundAgmatine, a potential novel therapeutic strategy for depression
Freitas, A. E., Neis, V. B., & Rodrigues, A. L. S. (2016) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.10.013 · Cited by 54
Bunevičius, A., Deltuva, V. P., & Tamašauskas, A. (2017) · Oncotarget · doi:10.18632/oncotarget.15743 · Cited by 51
“Untreated depression can increase risk for cardiovascular and cerebrovascular disorders that become increasingly common with advancing age [29, 30].”
BackgroundOuyang, P., WENGER, N. K., Taylor, D. A., Rich-Edwards, J. W., Steiner, M. S., Shaw, L. J., Berga, S. L., Miller, V. M., & Merz, C. N. B. (2016) · Biology of Sex Differences · doi:10.1186/s13293-016-0073-y · Cited by 54
“The AHA has recognized depression as a risk factor for poor prognosis among patients with acute coronary syndrome [236]”
BackgroundDepression and chest pain in patients with coronary artery disease
Hayek, S. S., Ko, Y.-A., Awad, M., Soto, A. D. M., Ahmed, H., Patel, K., Yuan, M., Maddox, S., Gray, B., Hajjari, J., et al. (2016) · International Journal of Cardiology · doi:10.1016/j.ijcard.2016.12.091 · Cited by 46
Self-citationComparison of treatment options for depression in heart failure: A network meta-analysis
Das, A., Roy, B., Schwarzer, G., Silverman, M. G., Ziegler, O., Bandyopadhyay, D., Philpotts, L. L., Sinha, S., Blumenthal, J. A., & Das, S. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.10.007 · Cited by 50
Self-citationMuse, E. D., & Topol, E. J. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.02.002 · Cited by 50
Depression increased risk of coronary heart disease: A meta-analysis of prospective cohort studies
Cao, H., Zhao, H., & Shen, L. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.913888 · Cited by 47
Desai, U., Martis, R. J., Nayak, C. G., Seshikala, G., Sarika, K., & Ranjan Shetty, K. (2016) · Journal of Mechanics in Medicine and Biology · doi:10.1142/s0219519416400121 · Cited by 50
Jain, R., Stone, J. A., Agarwal, G., Andrade, J. G., Bacon, S., BAJAJ, H. S., Baker, B., Cheng, G., Dannenbaum, D. A., Gelfer, M., et al. (2022) · Canadian Medical Association Journal · doi:10.1503/cmaj.220138 · Cited by 50
Wu, Q., Miao, X.-Y., Cao, Y.-Y., Chi, A.-P., & Xiao, T. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1243213 · Cited by 46
Psychological distress in adults with congenital heart disease: focus beyond depression
Gleason, L. P., Deng, L. X., Khan, A. M., Drajpuch, D. B., Fuller, S., Ludmir, J., Mascio, C. E., Partington, S. L., Tobin, L., Kim, Y. Y., et al. (2019) · Cardiology in the Young · doi:10.1017/s1047951118002068 · Cited by 48
“This likely reflects the known link between depression and poorer prognosis among adults with acquired heart disease.(8) However, as the connections between stress and anxiety with cardiovascular disease are further elucidated,(9,10) a broader definition of psychological distress among adults with CHD becomes necessar…”
BackgroundAssociations between depression and cardiometabolic health: A 27-year longitudinal study
Ditmars, H. L., Logue, M. W., Toomey, R., McKenzie, R. E., Franz, C. E., Panizzon, M. S., Reynolds, C. A., Cuthbert, K., Vandiver, R. A., Gustavson, D. E., et al. (2021) · Psychological Medicine · doi:10.1017/s003329172000505x · Cited by 48
“Additionally, current clinical recommendations acknowledge that depression may confer risk for poor prognosis among patients with acute coronary syndrome (Lichtman et al., 2014).”
Holdgaard, A., Eckhardt-Hansen, C., Lassen, C. F., Kjesbu, I. E., Dall, C. H., Michaelsen, K. L., Sibilitz, K. L., Prescott, E., & Rasmusen, H. K. (2022) · European Heart Journal · doi:10.1093/eurheartj/ehac792 · Cited by 47
Liu, H., Zhou, Z., Fan, X., Shen, C., Ma, Y., Sun, H., & Xu, Z. (2023) · International Journal of Public Health · doi:10.3389/ijph.2023.1605572 · Cited by 47
Ernstsen, L., Rangul, V., Nauman, J., Nes, B. M., Dalen, H., Krokstad, S., Lavie, C. J., Blair, S. N., & Wisløff, U. (2015) · The American Journal of Medicine · doi:10.1016/j.amjmed.2015.08.012 · Cited by 47
Nurse-Led Multidisciplinary Heart Failure Group Clinic Appointments
Smith, C. E., Piamjariyakul, U., Dalton, K. M., Russell, C., Wick, J., & Ellerbeck, E. F. (2015) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000255 · Cited by 49
Meneghetti, C. C., Guidolin, B. L., Zimmermann, P. R., & Sfoggia, A. (2017) · Trends in Psychiatry and Psychotherapy · doi:10.1590/2237-6089-2016-0004 · Cited by 52
Huffman, J. C., Adams, C. N., & Celano, C. M. (2017) · Psychosomatics · doi:10.1016/j.psym.2017.09.003 · Cited by 49
Bryson, E. O., Aloysi, A. S., Farber, K. G., & Kellner, C. H. (2017) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000001873 · Cited by 51
Kahl, K. G., Stapel, B., & Frieling, H. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.09.004 · Cited by 47
“, 2009), so that WHO and the American Heart Association consider depression as a major risk factor for coronary heart disease, similar to hyperlipidemia, diabetes, hypertension, and smoking (Lichtman et al., 2014; Chaddha et al., 2016).”
Brain–heart communication in health and diseases
Liu, W., Zhang, X., Wu, Z., Huang, K., Yang, C., & Yang, L. (2022) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2022.02.012 · Cited by 49
Levine, G. N., Carney, R. M., Cohen, B. E., Dunn, S. L., Gaffey, A. E., Kronish, I. M., Olsson, E. M. G., & Huffman, J. C. (2025) · Circulation · doi:10.1161/cir.0000000000001381 · Cited by 52
Self-citationPaine, N. J., Watkins, L. L., Blumenthal, J. A., Kuhn, C. M., & Sherwood, A. (2015) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000144 · Cited by 48
“In addition to traditional CVD risk factors, including smoking, obesity, and physical inactivity, accumulating evidence now exists indicating that depression is a risk factor for the development and exacerbation of CVD (2,3) and other acute coronary syndromes (4).”
BackgroundSelf-citationde Jager, T. A. J., Dulfer, K., Radhoe, S. P., Bergmann, M. J., Daemen, J., van Domburg, R. T., Lenzen, M. J., & Utens, E. M. W. J. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.10.005 · Cited by 46
Wei, J., Pimple, P. M., Shah, A. J., Rooks, C. R., Bremner, J. D., Nye, J. A., Ibeanu, I., Murrah, N. V., Shallenberger, L. H., Raggi, P., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102986 · Cited by 45
“Depression is a prevalent, debilitating, and underdiagnosed condition that affects approximately 20% of patients with recent myocardial infarction (MI), and is associated with increased risk of recurrent cardiac events [1].”
BackgroundSelf-citationThe association between heart diseases and suicide: a nationwide cohort study
Petersen, B. D., Stenager, E. N., Mogensen, C. B., & Erlangsen, A. (2020) · Journal of Internal Medicine · doi:10.1111/joim.13025 · Cited by 45
Cardiac Rehabilitation: A Bibliometric Review From 2001 to 2020
Yuan, G., Shi, J., Jia, Q., Shi, S., Zhu, X., Zhou, Y., Shi, S., & Hu, Y. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.672913 · Cited by 47
Sariaslan, A., Sharpe, M., Larsson, H., Wolf, A., Lichtenstein, P., & Fazel, S. (2022) · PLoS Medicine · doi:10.1371/journal.pmed.1003864 · Cited by 47
Metadata
- Authors
- Lichtman, J. H., Froelicher, E. S., Blumenthal, J. A., Carney, R. M., Doering, L. V., Frasure-Smith, N., Freedland, K. E., Jaffe, A. S., Leifheit-Limson, E. C., Sheps, D. S., Vaccarino, V., & Wulsin, L.
- ORCID
- Venue
- Circulation
- Published
- 2014-03-25
- Volume
- 129
- Issue
- 12
- Pages
- 1350-1369
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2137977071
- Cited by
- 1,208
- References
- 129
- Citations by year
- 2026: 65 · 2025: 87 · 2024: 95 · 2023: 106 · 2022: 107 · 2021: 100 · 2020: 108 · 2019: 105 · 2018: 112 · 2017: 90 · 2016: 113 · 2015: 86 · 2014: 32
- FWCI
- 17.24
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- depression, acute coronary syndrome, cardiovascular risk factors, prognosis, all-cause mortality, cardiac mortality
- MeSH terms
- American Heart Association, Cardiology, Depression, Humans, Prognosis, Risk Factors, United States, Practice Guidelines as Topic, Evidence-Based Medicine, Acute Coronary Syndrome
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