AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 Update: A Guideline From the American Heart Association and American College of Cardiology Foundation
Open accessAbstract
The American Heart Association makes every effort to avoid any actual or potential
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Written from the paper’s full text.
TL;DR
This 2011 AHA/ACCF guideline updates secondary prevention and risk reduction recommendations for patients with coronary and other atherosclerotic vascular disease, expanding the scope to include peripheral artery, atherosclerotic aortic, and carotid artery disease. It emphasizes comprehensive risk factor management and provides ACCF/AHA class/level-of-evidence recommendations for lipids, lifestyle, diabetes, antiplatelet/anticoagulant therapy, vaccination, depression, and cardiac rehabilitation.
Key findings
- For lipids, LDL-C should be <100 mg/dL for all patients with CHD and other clinical forms of atherosclerotic disease; treating very high-risk patients to LDL-C <70 mg/dL is reasonable; when triglycerides are ≥200 mg/dL, a non-HDL-C goal of <100 mg/dL is reasonable; if LDL-C is above 100 mg/dL, an adequate statin dose should achieve at least a 30% LDL-C lowering.
- Lifestyle goals include BMI 18.5 to 24.9 kg/m², waist circumference <35 inches (<89 cm) in women and <40 inches (<102 cm) in men, 30 to 60 minutes of moderate-intensity aerobic activity at least 5 and preferably 7 days per week, and an initial weight-loss goal of approximately 5% to 10% from baseline.
- Antiplatelet recommendations include aspirin 75–162 mg daily for all patients with coronary artery disease unless contraindicated; after ACS or PCI with stent placement, a P2Y12 receptor antagonist plus aspirin is indicated, with clopidogrel 75 mg daily, prasugrel 10 mg daily, or ticagrelor 90 mg twice daily for at least 12 months.
- Other recommendations include annual influenza vaccination for patients with cardiovascular disease, referral of eligible patients to comprehensive outpatient cardiovascular rehabilitation, metformin as effective first-line pharmacotherapy for type 2 diabetes (Class IIa, Level of Evidence A), and a target HbA1c ≤7% that may be considered.
Methods
- This is an AHA/ACCF guideline update that reviewed evidence from recent clinical trials and revised practice guidelines, using a process of partial adaptation of other guideline statements and reports plus supplemental literature review.
- Literature searches were limited to studies, reviews, and other evidence in human subjects published in English; topics included clinical trials, secondary prevention, atherosclerosis, and coronary/cerebral/peripheral artery disease, and the writing group also reviewed prior AHA, ACCF, and National Institutes of Health documents.
- Recommendations are expressed in ACCF/AHA format with Class of Recommendation and Level of Evidence.
Limitations
- The writing group acknowledges that ethnic minorities, women, and the elderly are underrepresented in many trials and urges physician and patient participation in trials to provide additional evidence for these groups.
- The paper states that no studies have directly tested treatment-to-target strategies; LDL-C and non-HDL-C targets are derived from achieved levels in randomized controlled trials and are considered Level of Evidence C.
- The writing group agreed to make no further changes in dyslipidemia recommendations pending the expected 2012 NHLBI ATP guidelines and made similar deferrals for hypertension pending the expected JNC guidelines; the text also makes evident that this is a guideline/consensus document rather than a primary trial, with many recommendations based on Level B or C evidence.
Model-written summary. Check it against the paper before relying on it.
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Cites
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Claims the paper makes
0 of 22 cited sources checked · 0 supported · 0 flagged
- Findingnone given
No studies have directly tested treatment to target strategies.
“Although no studies have directly tested treatment to target strategies”
Quote in the paperSubstantial claim - Findingcitation
Lipid reduction trials published between 2002 and 2006 included more than 50,000 patients.
“the lipid reduction trials published between 2002 and 2006 18,25,166 -168 included Ͼ50 000 patients”
Quote in the paperNot a substantial claim0 of 5 sources checked - Findingcitation
Aspirin dosing regimens ranging from 100 to 325 mg daily for 1 year appear efficacious for reducing saphenous vein graft closure after coronary artery bypass grafting.
“Dosing regimens ranging from 100 to 325 mg daily for 1 year appear to be efficacious.”
Quote in the paperSubstantial claim0 of 4 sources checked - Findingcitation
Many patients in whom therapies are indicated are not receiving them in actual clinical practice.
“multiple studies of the use of these recommended therapies in appropriate patients, although showing slow improvement, continue to support the discouraging conclusion that many patients in whom therapies are indicated are not receiving them in actual clinical practice.”
Quote in the paperSubstantial claim - Findingnone given
Treatment of depression has not been shown to improve cardiovascular disease outcomes.
“Treatment of depression has not been shown to improve cardiovascular disease outcomes but may be reasonable for its other clinical benefits.”
Quote in the paperSubstantial claim
- Findingnone given
If it is not possible to attain LDL-C <70 mg/dL because of a high baseline LDL-C, it generally is possible to achieve LDL-C reductions of >50% with either statins or LDL-C-lowering drug combinations.
“Furthermore, if it is not possible to attain LDL-C Ͻ70 mg/dL because of a high baseline LDL-C, it generally is possible to achieve LDL-C reductions of Ͼ50% with either statins or LDL-Clowering drug combinations.”
Quote in the paperSubstantial claim - Findingcitation
Use of warfarin in conjunction with aspirin and/or clopidogrel is associated with increased risk of bleeding.
“Use of warfarin in conjunction with aspirin and/or clopidogrel is associated with increased risk of bleeding and should be monitored closely.”
Quote in the paperSubstantial claim0 of 3 sources checked - Findingnone given
The combination of high-dose statin plus fibrate (especially gemfibrozil) can increase risk for severe myopathy.
“The combination of high-dose statin plus fibrate (especially gemfibrozil) can increase risk for severe myopathy.”
Quote in the paperNot a substantial claim - Premisecitation
Two additional trials demonstrated cardiovascular benefit for lipid lowering significantly below current cholesterol goal levels for those with chronic coronary heart disease.
“Subsequent to the 2004 update of ATP III, 2 additional trials 26,27 demonstrated cardiovascular benefit for lipid lowering significantly below current cholesterol goal levels for those with chronic coronary heart disease.”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisecitation
Carvedilol, metoprolol succinate, and bisoprolol have been shown to reduce mortality.
“(Use should be limited to carvedilol, metoprolol succinate, or bisoprolol, which have been shown to reduce mortality.)138,140,141”
Quote in the paperSubstantial claim0 of 3 sources checked - Interpretationnone given
The benefits of lipid-lowering therapy are in proportion to the reduction in LDL-C.
“The benefits of lipid-lowering therapy are in proportion to the reduction in LDL-C”
Quote in the paperSubstantial claim - Premisenone given
Additional studies have further confirmed the benefit of aldosterone antagonist therapy among patients with impaired left ventricular function.
“The results of additional studies have further confirmed the benefit of aldosterone antagonist therapy among patients with impaired left ventricular function.”
Quote in the paperSubstantial claim - Premisecitation
Individuals who have chronic disorders of the cardiovascular system are at increased risk for complications from influenza.
“According to the US Centers for Disease Control and Prevention, vaccination with inactivated influenza vaccine is recommended for individuals who have chronic disorders of the cardiovascular system because they are at increased risk for complications from influenza.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [147]
Not checked in the free run.
- Premisereasoning
Target LDL-C and non-HDL-C levels are derived from several randomized controlled trials where the LDL-C levels achieved for patients showing benefit are used to suggest targets.
“the target LDL-C and non-HDL-C levels are derived from several randomized controlled trials where the LDL-C levels achieved for patients showing benefit are used to suggest targets.”
Quote in the paperSubstantial claim - Interpretationreasoning
In patients with atherosclerotic vascular disease, comprehensive risk factor management reduces risk as assessed by improved survival, reduced recurrent events, need for revascularization procedures, and improved quality of life.
“Indeed, the growing body of evidence confirms that in patients with atherosclerotic vascular disease, comprehensive risk factor management reduces risk as assessed by a variety of outcomes, including improved survival, reduced recurrent events, the need for revascularization procedures, and improved quality of life.”
Quote in the paperSubstantial claim
- Classified as probably not a substantial claim. 3
- May combine two claims. 2
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenEthnic minorities, women, and the elderly are underrepresented in many trials.
“The committee acknowledges that ethnic minorities, women, and the elderly are underrepresented in many trials and urges physician and patient participation in trials that will provide additional evidence with regard to therapeutic strategies for these groups of patients.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Premisenone givenThe use of bile acid sequestrants is relatively contraindicated when triglycerides are ≥200 mg/dL and is contraindicated when triglycerides are ≥500 mg/dL.
“The use of bile acid sequestrants is relatively contraindicated when triglycerides are Ն200 mg/dL and is contraindicated when triglycerides are Ն500 mg/dL.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationComprehensive exercise-based outpatient cardiac rehabilitation is safe and beneficial for clinically stable outpatients with a history of heart failure.
“A comprehensive exercise-based outpatient cardiac rehabilitation program can be safe and beneficial for clinically stable outpatients with a history of heart failure.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites 159,159a-159c
Not checked in the free run.
Classified as probably not a substantial claim.
PremisecitationMetformin is an effective first-line pharmacotherapy for type 2 diabetes management (for prevention of cardiovascular complications) if not contraindicated.
“Metformin is an effective first-line pharmacotherapy and can be useful if not contraindicated.”
Quote in the paperSubstantial claim0 of 3 sources checked
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Aspirin use increases the risk of bleeding.
“Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear.”
From Effects of aspirin for primary prevention in persons with diabetes mellitus (2018) · cites this paper as [2]
The Antiplatelet agents/anticoagulants recommendations (page unavailable) state that warfarin used with aspirin and/or clopidogrel is associated with increased bleeding risk. The References also list a study of bleeding complications at different aspirin doses, but the guideline passage does not establish the unqualified claim that aspirin use alone increases bleeding risk. (LLM, conf=0.81)
Experimental — accuracy not yet measuredAspirin use reduces the risk of occlusive vascular events.
“Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear.”
From Effects of aspirin for primary prevention in persons with diabetes mellitus (2018) · cites this paper as [2]
The balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear.
“Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first cardiovascular events in patients with diabetes is unclear.”
From Effects of aspirin for primary prevention in persons with diabetes mellitus (2018) · cites this paper as [2]
The Antiplatelet agents/anticoagulants recommendations (page unavailable) address aspirin for patients with established coronary or other atherosclerotic disease, not prevention of a first cardiovascular event in patients with diabetes. Searches for the claimed uncertainty and for aspirin’s benefits and bleeding hazards in diabetic primary prevention found no passage in our copy that addresses that balance. (LLM, conf=0.72)
Experimental — accuracy not yet measuredThe old folklore that behavior cannot be changed has been dispelled by numerous randomized controlled trials of effective behavioral interventions.
“The old folklore that “behavior can’t be changed” has been dispelled by numerous randomized controlled trials of effective behavioral interventions.13–23”
From Better Population Health Through Behavior Change in Adults: A Call to Action (2013) · cites this paper as [17]
Cites
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271 · see citing works
Self-citationDetection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Grundy, S. M., Becker, D. M., Clark, L. T., Cooper, R., Denke, M. A., Howard, J. L., Hunninghake, D. B., Illingworth, D. R., Luepker, R. V., McBride, P. E., et al. (2002) · Civil War Book Review · Cited by 12,198 · see citing works
Self-citationGrundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.169404 · Cited by 11,961 · see citing works
Self-citationThe Physical Activity Guidelines for Americans
Piercy, K. L., Troiano, R. P., Ballard, R. M., Carlson, S. A., Fulton, J. E., Galuska, D. A., George, S. M., & Olson, R. D. (2018) · JAMA · doi:10.1001/jama.2018.14854 · Cited by 9,755 · see citing works
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,452 · see citing works
(2000) · New England Journal of Medicine · doi:10.1056/nejm200001203420301 · Cited by 8,663 · see citing works
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,479 · see citing works
Self-citationAntman, E. M., Anbe, D. T., Armstrong, P. W., Bates, E., Green, L. A., Hand, M. M., Hochman, J. S., Krumholz, H. M., Kushner, F. G., Lamas, G. A., et al. (2004) · Circulation · doi:10.1161/01.cir.0000134791.68010.fa · Cited by 8,345 · see citing works
Self-citation10-year follow-up of intensive glucose control in type 2 diabetes
Holman, R. R., Paul, S. K., Bethel, M. A., Matthews, D. R., & Neil, H. A. W. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0806470 · Cited by 7,751 · see citing works
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
Wallentin, L., Becker, R. C., Budaj, A., Cannon, C. P., Emanuelsson, H., Held, C., Horrow, J., Husted, S., James, S., Katus, H., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0904327 · Cited by 7,117 · see citing works
Collaboration, A. T. (2002) · BMJ · doi:10.1136/bmj.324.7329.71 · Cited by 6,943 · see citing works
Grundy, S. M., Cleeman, J. I., Merz, C. N. B., Brewer, H. B., Clark, L. T., Hunninghake, D. B., Pasternak, R. C., Smith, S. C., & Stone, N. J. (2004) · Circulation · doi:10.1161/01.cir.0000133317.49796.0e · Cited by 6,902 · see citing works
Self-citationPrasugrel versus clopidogrel in patients with acute coronary syndromes
Wiviott, S. D., Braunwald, E., McCabe, C. H., Montalescot, G., Ruzyllo, W., Gottlieb, S., Neumann, F.-J., Ardissino, D., De Servi, S., Murphy, S. A., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa0706482 · Cited by 6,790 · see citing works
Cholesterol Treatment Trialists' (CTT) Collaboration (2010) · The Lancet · doi:10.1016/s0140-6736(10)61350-5 · Cited by 6,550 · see citing works
(2007) · Circulation · doi:10.1161/circulationaha.107.185649 · Cited by 6,545 · see citing works
Self-citation(1996) · The Lancet · doi:10.1016/s0140-6736(96)09457-3 · Cited by 6,503 · see citing works
(2001) · New England Journal of Medicine · doi:10.1056/nejmoa010746 · Cited by 6,470 · see citing works
Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Adams, R. J., Berry, J. D., Brown, T. M., Carnethon, M. R., Dai, S., de Simone, G., Ford, E. S., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182009701 · Cited by 6,149 · see citing works
Self-citationA Clinical Trial of the Effects of Dietary Patterns on Blood Pressure
Appel, L. J., Moore, T. J., Obarzanek, E., Vollmer, W. M., Svetkey, L. P., Sacks, F. M., Bray, G. A., Vogt, T. M., Cutler, J. A., Windhauser, M. M., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704173361601 · Cited by 5,981 · see citing works
The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.23.2981 · Cited by 5,664 · see citing works
Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., Obarzanek, E., Conlin, P. R., Miller, E. R., Simons-Morton, D. G., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440101 · Cited by 5,638 · see citing works
Kernan, W. N., Ovbiagele, B., Black, H. R., Bravata, D. M., Chimowitz, M. I., Ezekowitz, M. D., Fang, M. C., Fisher, M., Furie, K. L., Heck, D. V., et al. (2014) · Stroke · doi:10.1161/str.0000000000000024 · Cited by 5,170 · see citing works
Pitt, B., Remme, W., Zannad, F., Neaton, J., Martinez, F., Roniker, B., Bittman, R., Hurley, S., Kleiman, J., & Gatlin, M. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030207 · Cited by 4,941 · see citing works
Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes
Cannon, C. P., Braunwald, E., McCabe, C. H., Rader, D. J., Rouleau, J. L., Belder, R., Joyal, S. V., Hill, K. A., Pfeffer, M. A., & Skene, A. M. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040583 · Cited by 4,938 · see citing works
Lloyd-Jones, D. M., Hong, Y., Labarthe, D., Mozaffarian, D., Appel, L. J., Van Horn, L., Greenlund, K., Daniels, S., Nichol, G., Tomaselli, G. F., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.192703 · Cited by 4,750 · see citing works
Self-citationThe Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure
Packer, M., Bristow, M. R., Cohn, J. N., Colucci, W. S., Fowler, M. B., Gilbert, E. M., & Shusterman, N. H. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605233342101 · Cited by 4,649 · see citing works
Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia
Frick, M. H., Elo, O., Haapa, K., Heinonen, O. P., Heinsalmi, P., Helo, P., Huttunen, J. K., Kaitaniemi, P., Koskinen, P., Manninen, V., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711123172001 · Cited by 3,881 · see citing works
Treating Tobacco Use and Dependence: 2008 Update
Panel, T. U. A. D. G. (2008) · PsycEXTRA Dataset · doi:10.1037/e566222009-001 · Cited by 3,864 · see citing works
Sever, P., Dahlöf, B., Poulter, N. R., Wedel, H., Beevers, G., Caulfield, M. J., Collins, R., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12948-0 · Cited by 3,756 · see citing works
Hirsch, A. T., Haskal, Z. J., Hertzer, N. R., Bakal, C. W., Creager, M. A., Halperin, J. L., Hiratzka, L. F., Murphy, W. R. C., Olin, J. W., Puschett, J. B., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.174526 · Cited by 3,708 · see citing works
Self-citationFish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
Kris-Etherton, P. M., Harris, W. S., & Appel, L. J. (2002) · Circulation · doi:10.1161/01.cir.0000038493.65177.94 · Cited by 3,707 · see citing works
Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults
Calle, E. E., Thun, M. J., Petrelli, J. M., Rodriguez, C., & Heath, C. W. (1999) · New England Journal of Medicine · doi:10.1056/nejm199910073411501 · Cited by 3,643 · see citing works
Treating tobacco use and dependence-Clinical practice guideline
Mc, F. (2000) · Medical Entomology and Zoology · Cited by 3,616 · see citing works
Telmisartan, ramipril, or both in patients at high risk for vascular events
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801317 · Cited by 3,502 · see citing works
Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease
LaRosa, J. C., Grundy, S. M., Waters, D. D., Shear, C., Barter, P., Fruchart, J.-C., Gotto, A. M., Greten, H., Kastelein, J. J. P., Shepherd, J., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050461 · Cited by 3,489 · see citing works
Self-citationRubins, H. B., Robins, S. J., Collins, D., Fye, C. L., Anderson, J. W., Elam, M. B., Faas, F. H., Linares, E., Schaefer, E. J., Schectman, G., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908053410604 · Cited by 3,439 · see citing works
Shepherd, J., Blauw, G. J., Murphy, M. B., Bollen, E. L., Buckley, B. M., Cobbe, S. M., Ford, I., Gaw, A., Hyland, M., Jukema, J. W., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11600-x · Cited by 3,378 · see citing works
2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
Levine, G. N., Bates, E., Blankenship, J. C., Bailey, S. R., Bittl, J. A., Cercek, B., Chambers, C. E., Ellis, S. G., Guyton, R. A., Hollenberg, S. M., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31823ba622 · Cited by 3,289 · see citing works
Eplerenone in patients with systolic heart failure and mild symptoms
Zannad, F., McMurray, J. J. V., Krum, H., van Veldhuisen, D. J., Swedberg, K., Shi, H., Vincent, J., Pocock, S. J., & Pitt, B. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1009492 · Cited by 3,111 · see citing works
Early and Sustained Dual Oral Antiplatelet Therapy Following Percutaneous Coronary Intervention
Steinhubl, S. R., Berger, P. B., Mann, J. T., Fry, E. T. A., DeLago, A. J., Wilmer, C. I., Topol, E. J., & for the CREDO Investigators (2002) · JAMA · doi:10.1001/jama.288.19.2411 · Cited by 3,071 · see citing works
Mehta, S. R., Yusuf, S., Peters, R. J. G., Bertrand, M. E., Lewis, B. S., Natarajan, M. K., Malmberg, K., Rupprecht, H.-J., Zhao, F., Chrolavicius, S., et al. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05701-4 · Cited by 2,937 · see citing works
Standards of medical care in diabetes—2011
American Diabetes Association (2011) · Diabetes Care · doi:10.2337/dc11-s011 · Cited by 2,880 · see citing works
Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events
Bhatt, D. L., Fox, K. A. A., Hacke, W., Berger, P. B., Black, H. R., Boden, W. E., Cacoub, P., Cohen, E. A., Creager, M. A., Easton, J. D., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa060989 · Cited by 2,819 · see citing works
Self-citationDennis, M. S. (1996) · The Lancet · Cited by 2,724 · see citing works
Mehta, S. R., Yusuf, S., & Peters, R. J. G. (2002) · ACC Current Journal Review · doi:10.1016/s1062-1458(02)00559-7 · Cited by 2,579 · see citing works
Cytochrome P-450 Polymorphisms and Response to Clopidogrel
Mega, J. L., Close, S. L., Wiviott, S. D., Shen, L., Hockett, R. D., Brandt, J. T., Walker, J. R., Antman, E. M., Macias, W. L., D, E. B. M., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0809171 · Cited by 2,496 · see citing works
Pfeffer, M. A., McMurray, J. J. V., Velazquez, E. J., Rouleau, J.-L., Køber, L., Maggioni, A. P., Solomon, S. D., Swedberg, K., Van de Werf, F., White, H., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa032292 · Cited by 2,471 · see citing works
Obesity and Cardiovascular Disease
Lavie, C. J., Milani, R. V., & Ventura, H. O. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.12.068 · Cited by 2,326 · see citing works
Taylor, R. S., Brown, A., Ebrahim, S., Jolliffe, J., Noorani, H., Rees, K., Skidmore, B., Stone, J. A., Thompson, D. R., & Oldridge, N. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.01.009 · Cited by 2,239 · see citing works
O'Connor (2009) · doi:10.1001/jama.2009.454 · Cited by 2,173 · see citing works
Mosca, L., Benjamin, E. J., Berra, K., Bezanson, J. L., Dolor, R. J., Lloyd-Jones, D. M., Newby, L. K., Piña, I. L., Roger, V. L., Shaw, L. J., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31820faaf8 · Cited by 2,143 · see citing works
Self-citationThompson, P. D., Buchner, D., Piña, I. L., Balady, G. J., Williams, M. A., Marcus, B. H., Berra, K., Blair, S. N., Costa, F., Franklin, B., et al. (2003) · Circulation · doi:10.1161/01.cir.0000075572.40158.77 · Cited by 2,132 · cited 1× · see citing works
“Lifestyle modifications including daily physical activity, weight management, blood pressure control, and lipid management are recommended for all patients with diabetes.(19,22-24,29,56,58,59,62,66,74,162) (Level of Evidence: B)”
BackgroundSelf-citationSmith, S. C., Allen, J. K., Blair, S. N., Bonow, R. O., Brass, L. M., Fonarow, G. C., Grundy, S. M., Hiratzka, L. F., Jones, D. W., Krumholz, H. M., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.174516 · Cited by 2,087 · see citing works
Self-citationRisk Factors for Stroke and Efficacy of Antithrombotic Therapy in Atrial Fibrillation
(1994) · Archives of Internal Medicine · doi:10.1001/archinte.1994.00420130036007 · Cited by 2,066 · see citing works
Clinical Practice Guideline: Otitis Media with Effusion (Update)
Rosenfeld, R. M., Shin, J. J., Schwartz, S. R., Coggins, R., Gagnon, L., Hackell, J. M., Hoelting, D., Hunter, L. L., Kummer, A. W., Payne, S. C., et al. (2016) · Otolaryngology–Head and Neck Surgery · doi:10.1177/0194599815623467 · Cited by 2,006 · see citing works
Brown, B. G., Zhao, X.-Q., Chait, A., Fisher, L. D., Cheung, M. C., Morse, J. S., Dowdy, A. A., Marino, E. K., Bolson, E. L., Alaupovic, P., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011090 · Cited by 1,979 · see citing works
Effect of Aerobic Exercise on Blood Pressure: A Meta-Analysis of Randomized, Controlled Trials
Whelton, S. P., Chin, A., Xin, X., & He, J. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-7-200204020-00006 · Cited by 1,970 · see citing works
Fiore, A. E., Uyeki, T. M., Broder, K. R., Finelli, L., Euler, G. L., Singleton, J. A., Iskander, J. K., Wortley, P. M., Shay, D. K., Bresee, J., et al. (2009) · PubMed · Cited by 1,964 · see citing works
Pitt, B., Poole-Wilson, P. A., Segal, R., Martínez, F. A., Dickstein, K., Camm, A. J., Konstam, M. A., Riegger, G. A. J., Klinger, G. H., Neaton, J. D., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02213-3 · Cited by 1,954 · see citing works
Pfeffer, M. A., Swedberg, K. B., Granger, C. B., Held, P., McMurray, J. J. V., Michelson, E. L., Olofsson, B., Östergren, J., & Yusuf, S. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14282-1 · Cited by 1,885 · see citing works
The Health Consequences of Involuntary Exposure to Tobacco Smoke: A Report of the Surgeon General
(2006) · PsycEXTRA Dataset · doi:10.1037/e601432007-001 · Cited by 1,877 · see citing works
Poole-Wilson, P. A., Swedberg, K., Cleland, J. G., Di Lenarda, A., Hanrath, P., Komajda, M., Lubsen, J., Lutiger, B., Metra, M., Remme, W. J., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13800-7 · Cited by 1,872 · see citing works
Gibbons, R., Abrams, J., Chatterjee, K., Daley, J., Deedwania, P., Douglas, J. S., Ferguson, T., Fihn, S. D., Fraker, T., Gardin, J. M., et al. (2003) · Circulation · doi:10.1161/01.cir.0000047041.66447.29 · Cited by 1,830 · see citing works
Self-citationFifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin
Canner, P. L., Berge, K. G., Wenger, N. K., Stamler, J., Friedman, L., Prineas, R. J., & Friedewald, W. (1986) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(86)80293-5 · Cited by 1,824 · see citing works
Gibbons, R. J., Abrams, J., Chatterjee, K., Daley, J., DEEDWANIA, P. C., Douglas, J. S., Ferguson, T. B., Fihn, S. D., Fraker, T. D., Gardin, J. M., et al. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02848-6 · Cited by 1,688 · see citing works
Self-citationbeta Blockade after myocardial infarction: systematic review and meta regression analysis
Freemantle, N., Cleland, J., Young, P., Mason, J., & Harrison, J. (1999) · BMJ · doi:10.1136/bmj.318.7200.1730 · Cited by 1,509 · see citing works
Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack
Furie, K. L., Kasner, S. E., Adams, R. J., Albers, G. W., Bush, R. L., Fagan, S. C., Halperin, J. L., Johnston, S. C., Katzan, I. L., Kernan, W. N., et al. (2010) · Stroke · doi:10.1161/str.0b013e3181f7d043 · Cited by 1,492 · see citing works
Self-citationRay, K. K., Seshasai, S. R. K., Wijesuriya, S., Sivakumaran, R., Nethercott, S., Preiss, D., Erqou, S., & Sattar, N. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60697-8 · Cited by 1,383 · see citing works
ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction
Antman, E. M., Anbe, D. T., Armstrong, P. W., Bates, E., Green, L. A., Hand, M. M., Hochman, J. S., Krumholz, H. M., Kushner, F. G., Lamas, G. A., et al. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.07.014 · Cited by 1,312 · see citing works
Self-citationThe Effects of a Smoking Cessation Intervention on 14.5-Year Mortality: A Randomized Clinical Trial
Anthonisen, N. R., Skeans, M. A., Wise, R. A., Manfreda, J., Kanner, R. E., Connett, J. E., & for the Lung Health Study Research Group* (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-4-200502150-00005 · Cited by 1,237 · see citing works
Williams, M. A., Haskell, W. L., Ades, P. A., Amsterdam, E. A., Bittner, V., Franklin, B. A., Gulanick, M., Laing, S. T., & Stewart, K. J. (2007) · Circulation · doi:10.1161/circulationaha.107.185214 · Cited by 1,211 · see citing works
Self-citationIntensive glucose control and macrovascular outcomes in type 2 diabetes
Turnbull, F. M., Abraira, C., Anderson, R. J., Byington, R. P., Chalmers, J. P., Duckworth, W. C., Evans, G. W., Gerstein, H. C., Holman, R. R., Moritz, T. E., et al. (2009) · Diabetologia · doi:10.1007/s00125-009-1470-0 · Cited by 1,189 · see citing works
A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke
Mohr, J. P., Thompson, J. L. P., Lazar, R. M., Levin, B., Sacco, R. L., Furie, K. L., Kistler, J. P., Albers, G. W., Pettigrew, L. C., Adams, H. P., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011258 · Cited by 1,168 · see citing works
Self-citationThe way I see it: House officers need formal career development
Connor, A. (2002) · BMJ · doi:10.1136/bmj.324.7336.s71 · Cited by 1,146 · see citing works
Angiotensin-converting-enzyme inhibition in stable coronary artery disease
(2004) · New England Journal of Medicine · doi:10.1056/nejmoa042739 · Cited by 1,123 · see citing works
Balady (2007) · doi:10.1161/circulationaha.106.180945 · Cited by 1,118 · see citing works
Belardinelli, R., Georgiou, D., Cianci, G., & Purcaro, A. (1999) · Circulation · doi:10.1161/01.cir.99.9.1173 · Cited by 1,099 · see citing works
Cardiac Rehabilitation and Secondary Prevention of Coronary Heart Disease
Leon, A. S., Franklin, B. A., Costa, F., Balady, G. J., Berra, K. A., Stewart, K. J., Thompson, P. D., Williams, M. A., & Lauer, M. S. (2005) · Circulation · doi:10.1161/01.cir.0000151788.08740.5c · Cited by 1,066 · see citing works
Self-citationMontalescot, G., Wiviott, S. D., D, E. B. M., Murphy, S. A., Gibson, C. M., McCabe, C. H., & Antman, E. M. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60441-4 · Cited by 1,061 · see citing works
Kearon, C., Gent, M., Hirsh, J., Weitz, J. I., Kovacs, M. J., Anderson, D. R., Turpie, A. G. G., Green, D., Ginsberg, J. S., Wells, P. S., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903253401201 · Cited by 1,057 · see citing works
Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis
Dattilo, A., & Kris-Etherton, P. (1992) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/56.2.320 · Cited by 1,055 · see citing works
Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH)
Piepoli, M. F., Davos, C. H., Francis, D. P., & Coats, A. J. S. (2004) · BMJ · doi:10.1136/bmj.37938.645220.ee · Cited by 994 · see citing works
Meta-analysis: secondary prevention programs for patients with coronary artery disease
Clark, A. M., Hartling, L., Vandermeer, B., & McAlister, F. A. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-143-9-200511010-00010 · Cited by 979 · see citing works
Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke
Sacco, R. L., Diener, H.-C., Yusuf, S., Cotton, D., Ôunpuu, S., Lawton, W. A., Palesch, Y., Martin, R. H., Albers, G. W., Bath, P., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0805002 · Cited by 961 · see citing works
Self-citation(2011) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03793.x · Cited by 958 · see citing works
Klein, S., Burke, L. E., Bray, G. A., Blair, S., Allison, D. B., Pi-Sunyer, X., Hong, Y., & Eckel, R. H. (2004) · Circulation · doi:10.1161/01.cir.0000145546.97738.1e · Cited by 934 · see citing works
Rooke, T. W., Hirsch, A. T., Misra, S., Sidawy, A. N., Beckman, J. A., Findeiss, L., Golzarian, J., Gornik, H. L., Halperin, J. L., Jaff, M. R., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.023 · Cited by 925 · see citing works
Skyler, J. S., Bergenstal, R., Bonow, R. O., Buse, J., Deedwania, P., Gale, E. A. M., Howard, B. V., Kirkman, M. S., Kosiborod, M., Reaven, P., et al. (2009) · Diabetes Care · doi:10.2337/dc08-9026 · Cited by 881 · see citing works
Self-citationSurvival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study
Currie, C. J., Peters, J. R., Tynan, A., Evans, M., Heine, R. J., Bracco, O. L., Zagar, T., & Poole, C. D. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61969-3 · Cited by 874 · see citing works
Exercise for intermittent claudication
Lane, R., Harwood, A. E., Watson, L. C., & Leng, G. C. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000990.pub4 · Cited by 864 · see citing works
Warfarin, Aspirin, or Both after Myocardial Infarction
Hurlen, M., Abdelnoor, M., Smith, P., Erikssen, J., & Arnesen, H. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020496 · Cited by 846 · see citing works
Prognostic Value of a Treadmill Exercise Score in Outpatients with Suspected Coronary Artery Disease
Mark, D. B., Shaw, L. K., Harrell, F. E., Hlatky, M. A., Lee, K. L., Bengtson, J. R., McCants, C. B., Califf, R. M., & Pryor, D. B. (1991) · New England Journal of Medicine · doi:10.1056/nejm199109193251204 · Cited by 837 · see citing works
Bucher, H. C., Hengstler, P., Schindler, C., & Meier, G. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(01)01114-7 · Cited by 823 · see citing works
Bhatt, D. L., Flather, M. D., Hacke, W., Berger, P. B., Black, H. R., Boden, W. E., Cacoub, P., Cohen, E. A., Creager, M. A., Easton, J. D., et al. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.03.025 · Cited by 805 · see citing works
Self-citationBlood Pressure Lowering Treatment Trialists’ Collaboration (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.12.1410 · Cited by 786 · see citing works
Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy
Cannon, C. P., Steinberg, B. A., Murphy, S. A., Mega, J. L., & Braunwald, E. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.04.070 · Cited by 770 · see citing works
"Choking game" awareness and participation among 8th graders - Oregon, 2008.
Ramowski, S. K., Nystrom, R. J., Chaumeton, N. R., Rosenberg, K., & Gilchrist, J. (2010) · MMWR Morbidity and Mortality Weekly Report · Cited by 753 · see citing works
Hambrecht, R., Walther, C., Möbius-Winkler, S., Gielen, S., Linke, A., Conradi, K., Erbs, S., Kluge, R., Kendziorra, K., Sabri, O., et al. (2004) · Circulation · doi:10.1161/01.cir.0000121360.31954.1f · Cited by 752 · see citing works
Patrono, C., Baigent, C., Hirsh, J., & Roth, G. J. (2008) · CHEST Journal · doi:10.1378/chest.08-0672 · Cited by 749 · see citing works
Kunz, R., Friedrich, C., Wolbers, M., & Mann, J. F. E. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-1-200801010-00190 · Cited by 713 · see citing works
Gruberg, L., Weissman, N. J., Waksman, R., Fuchs, S., Deible, R., Pinnow, E. E., Ahmed, L. M., Kent, K. M., Pichard, A. D., Suddath, W. O., et al. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(01)01802-2 · Cited by 696 · see citing works
Aspirin and Mortality from Coronary Bypass Surgery
Mangano, D. T. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020798 · Cited by 674 · see citing works
Exercise Treadmill Score for Predicting Prognosis in Coronary Artery Disease
Mark, D. B., Hlatky, M. A., HARRELL, F. E., LEE, K. L., Califf, R. M., & PRYOR, D. B. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-106-6-793 · Cited by 666 · see citing works
Prediction of long-term prognosis in 12 169 men referred for cardiac rehabilitation
Kavanagh, T., Mertens, D. J., Hamm, L. F., Beyene, J., Kennedy, J., Corey, P., & Shephard, R. J. (2002) · Circulation · doi:10.1161/01.cir.0000024413.15949.ed · Cited by 648 · see citing works
Home-based versus centre-based cardiac rehabilitation
Taylor, R. S., Dalal, H., Jolly, K., Moxham, T., & Zawada, A. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007130.pub2 · Cited by 623 · see citing works
Ärnlöv, J., Ingelsson, E., Sundström, J., & Lind, L. (2009) · Circulation · doi:10.1161/circulationaha.109.887521 · Cited by 612 · see citing works
Yu-Poth, S., Zhao, G., Etherton, T., Naglak, M., Jonnalagadda, S., & Kris-Etherton, P. M. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.4.632 · Cited by 584 · see citing works
Screening for Depression in Adults: U.S. Preventive Services Task Force Recommendation Statement
U.S. Preventive Services Task Force* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-11-200912010-00006 · Cited by 581 · see citing works
A Comparison of Aspirin with Placebo in Patients Treated with Warfarin after Heart-Valve Replacement
Turpie, A. G. G., Gent, M., Laupacis, A., Latour, Y., Gunstensen, J., Basile, F., Klimek, M., & Hirsh, J. (1993) · New England Journal of Medicine · doi:10.1056/nejm199308193290802 · Cited by 546 · see citing works
Hammill, B. G., Curtis, L. H., Schulman, K. A., & Whellan, D. J. (2009) · Circulation · doi:10.1161/circulationaha.109.876383 · Cited by 536 · see citing works
Sever, P., Dahl??f, B., Poulter, N. R., Wedel, H., Beevers, G., Caulfield, M. J., Collins, R., Kjeldsen, S. E., Kristinsson, A., McInnes, G. T., et al. (2004) · Drugs · doi:10.2165/00003495-200464002-00005 · Cited by 524 · see citing works
Effect of Dipyridamole and Aspirin on Late Vein-Graft Patency after Coronary Bypass Operations
Chesebro, J. H., Fuster, V., Elveback, L. R., Clements, I. P., Smith, H. C., Holmes, D. R., Bardsley, W. T., Pluth, J. R., Wallace, R. B., Puga, F. J., et al. (1984) · New England Journal of Medicine · doi:10.1056/nejm198401263100401 · Cited by 516 · see citing works
Adams, R. J., Albers, G. W., Alberts, M. J., Benavente, O., Furie, K. L., Goldstein, L. B., Gorelick, P. B., Halperin, J. L., Harbaugh, R. E., Johnston, S. C., et al. (2008) · Stroke · doi:10.1161/strokeaha.107.189063 · Cited by 478 · see citing works
Self-citationDepression Screening and Patient Outcomes in Cardiovascular Care: A Systematic Review
Thombs, B. D., de Jonge, P., Coyne, J. C., Whooley, M. A., Frasure-Smith, N., Mitchell, A. J., Zuidersma, M., Eze-Nliam, C., Lima, B. B., Smith, C. G., et al. (2008) · JAMA · doi:10.1001/jama.2008.667 · Cited by 472 · see citing works
McDermott, M. M., Ades, P., Guralnik, J. M., Dyer, A., Ferrucci, L., Liu, K., Nelson, M., Lloyd-Jones, D., Van Horn, L., Garside, D., et al. (2009) · JAMA · doi:10.1001/jama.2008.962 · Cited by 449 · see citing works
Self-citationOral Anticoagulant and Antiplatelet Therapy and Peripheral Arterial Disease
(2007) · New England Journal of Medicine · doi:10.1056/nejmoa065959 · Cited by 442 · see citing works
Appel, L. J., Frohlich, E. D., Hall, J. E., Pearson, T. A., Sacco, R. L., Seals, D. R., Sacks, F. M., Smith, S. C., Vafiadis, D. K., & Horn, L. V. (2011) · Circulation · doi:10.1161/cir.0b013e31820d0793 · Cited by 391 · see citing works
Self-citationPeak oxygen intake and cardiac mortality in women referred for cardiac rehabilitation
Kavanagh, T., Mertens, D. J., Hamm, L. F., Beyene, J., Kennedy, J., Corey, P., & Shephard, R. J. (2003) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.07.028 · Cited by 380 · see citing works
Robinson, J. G., Wang, S., Smith, B. J., & Jacobson, T. A. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.024 · Cited by 368 · see citing works
Exercise Training for Type 2 Diabetes Mellitus
Marwick, T. H., Hordern, M., Miller, T. D., Chyun, D. A., Bertoni, A. G., Blumenthal, R. S., Philippides, G. J., & Rocchini, A. P. (2009) · Circulation · doi:10.1161/circulationaha.109.192521 · Cited by 368 · see citing works
Waist Circumference and All-Cause Mortality in a Large US Cohort
Jacobs, E. J. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.201 · Cited by 359 · see citing works
Systematic review: glucose control and cardiovascular disease in type 2 diabetes
Kelly, T. N., Bazzano, L. A., Fonseca, V. A., Thethi, T. K., Reynolds, K., & He, J. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-6-200909150-00137 · Cited by 358 · see citing works
Aspirin for the Prevention of Cardiovascular Events in Patients With Peripheral Artery Disease
Berger, J. S., Krantz, M. J., Kittelson, J. M., & Hiatt, W. R. (2009) · JAMA · doi:10.1001/jama.2009.623 · Cited by 357 · see citing works
Matchar, D. B., McCrory, D. C., Orlando, L. A., Patel, M. R., Patel, U. D., Patwardhan, M. B., Powers, B. J., Samsa, G. P., & Gray, R. N. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-1-200801010-00189 · Cited by 346 · see citing works
Skyler, J. S., Bergenstal, R. M., Bonow, R. O., Buse, J. B., DEEDWANIA, P. C., Gale, E. A., Howard, B. V., Kirkman, M. S., Kosiborod, M., Reaven, P. D., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.191305 · Cited by 345 · see citing works
Self-citationRollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Houck, P. R., Counihan, P. J., Kapoor, W. N., Schulberg, H. C., & Reynolds, C. F. (2009) · JAMA · doi:10.1001/jama.2009.1670 · Cited by 343 · see citing works
Serebruany, V. L., Steinhubl, S. R., Berger, P. B., Malinin, A. I., Baggish, J. S., Bhatt, D. L., & Topol, E. J. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.01.049 · Cited by 343 · see citing works
Rooke, T. W., Hirsch, A. T., Misra, S., Sidawy, A. N., Beckman, J. A., Findeiss, L., Golzarian, J., Gornik, H. L., Halperin, J. L., Jaff, M. R., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31822e80c3 · Cited by 335 · see citing works
Thomas, R. J., King, M. L., Lui, K., Oldridge, N., Piña, I. L., Spertus, J. A., Bonow, R. O., Estes, N. A. M., Goff, D. C., Grady, K. L., et al. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.04.033 · Cited by 323 · see citing works
Self-citationIMPROVED AORTOCORONARY BYPASS PATENCY BY LOW-DOSE ASPIRIN (100 mg DAILY)
Lorenz, R. L., Weber, M., Kotzur, J., Theisen, K., Schacky, C. V., Meister, W., Reichardt, B., & Weber, P. C. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92446-2 · Cited by 320 · see citing works
Oral Anticoagulant Therapy in Patients With Coronary Artery Disease: A Meta-analysis
Anand, S. S. (1999) · JAMA · doi:10.1001/jama.282.21.2058 · Cited by 311 · see citing works
Insulin Resistance and Cardiovascular Events With Low HDL Cholesterol
Robins, S. J., Bloomfield, H. E., Faas, F. H., Schaefer, E. J., Elam, M. B., Anderson, J. W., Collins, D. E., & on behalf of the VA-HIT Study Group (2003) · Diabetes Care · doi:10.2337/diacare.26.5.1513 · Cited by 308 · see citing works
Cardiovascular Outcomes in Trials of Oral Diabetes Medications: A Systematic Review
Selvin, E., Bolen, S., Yeh, H.-C., Wiley, C., Wilson, L. M., Marinopoulos, S. S., Feldman, L., Vassy, J., Wilson, R., Bass, E. B., et al. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.19.2070 · Cited by 300 · see citing works
Ginsberg, H. N., Kris‐Etherton, P. M., Dennis, B., Elmer, P. J., Ershow, A. G., LeFevre, M. L., Pearson, T. A., Roheim, P. S., Ramakrishnan, R., Reed, R. G., et al. (1998) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.18.3.441 · Cited by 294 · see citing works
Gurfinkel, E. (2003) · European Heart Journal · doi:10.1016/j.ehj.2003.10.018 · Cited by 268 · see citing works
Ciszewski, A., Bilińska, Z. T., Brydak, L. B., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehm581 · Cited by 266 · see citing works
Exercise for intermittent claudication
Watson, L. C., Ellis, B., & Leng, G. C. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000990.pub2 · Cited by 251 · see citing works
The Primary and Secondary Prevention of Coronary Artery Disease
Becker, R. C., Meade, T. W., Berger, P. B., Ezekowitz, M. D., O’Connor, C. M., Vorchheimer, D. A., Guyatt, G. H., Mark, D. B., & Harrington, R. A. (2008) · CHEST Journal · doi:10.1378/chest.08-0685 · Cited by 249 · see citing works
Fiore, L. D., Ezekowitz, M. D., Brophy, M. T., Lu, D., Sacco, J., & Peduzzi, P. (2002) · Circulation · doi:10.1161/hc0502.103329 · Cited by 224 · see citing works
Algra, A. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70685-8 · Cited by 222 · see citing works
(pebc, P. I. E.-B. C., (cco, C. C. O., Bolderston, A., Lloyd, N. S., Wong, R. K. S., Holden, L., Robb-blenderman, L., & Base, E. (2008) · Springer eBooks · doi:10.1007/978-1-4020-5614-7_417 · Cited by 209 · see citing works
Murphy, S., Cannon, C., Wiviott, S., McCabe, C., & Braunwald, E. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.10.005 · Cited by 202 · see citing works
Critical Leg Ischaemia Prevention Study (CLIPS) Group (2007) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2006.01763.x · Cited by 202 · see citing works
Prognostic significance of peak exercise capacity in patients with coronary artery disease
Vanhees, L., Fagard, R., Thijs, L., Staessen, J. A., & Amery, A. A. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90420-0 · Cited by 202 · see citing works
Hirsch, A., Haskal, Z., Hertzer, N., Bakal, C., Creager, M., Halperin, J., Hiratzka, L., Murphy, W. R. C., Olin, J., Puschett, J., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.173994 · Cited by 200 · see citing works
Self-citationPassino, C., Severino, S., Poletti, R., Piepoli, M. F., Mammini, C., Clerico, A., Gabutti, A., Nassi, G., & Emdin, M. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.12.050 · Cited by 195 · see citing works
Training Physicians in Counseling about Smoking Cessation
Cummings, S. R., Coates, T. J., Richard, R. J., Hansen, B., Zahnd, E. G., VanderMartin, R., Duncan, C. L., Gerbert, B., Martin, A., & Stein, M. J. (1989) · Annals of Internal Medicine · doi:10.7326/0003-4819-110-8-640 · Cited by 195 · see citing works
Steinhubl, S. R., Bhatt, D. L., Brennan, D. M., Montalescot, G., Hankey, G. J., Eikelboom, J. W., Berger, P. B., Topol, E. J., & on behalf of the CHARISMA Investigators (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-150-6-200903170-00006 · Cited by 179 · see citing works
Domanski, M. J., Krause-Steinrauf, H., Massie, B. M., Deedwania, P., Follmann, D., Kovar, D., Murray, D., Oren, R., Rosenberg, Y., Young, J., et al. (2003) · Journal of Cardiac Failure · doi:10.1054/s1071-9164(03)00133-7 · Cited by 176 · see citing works
Oral anticoagulants in patients with coronary artery disease
Anand, S. S., & Yusuf, S. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02776-6 · Cited by 174 · see citing works
Home-based versus centre-based cardiac rehabilitation
Taylor, R. S., Dalal, H. M., Jolly, K. B., Zawada, A., Dean, S. G., Cowie, A., & Norton, R. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007130.pub3 · Cited by 169 · see citing works
Schaefer, E. J., Lamon‐Fava, S., Ausman, L., Ordovás, J. M., Clevidence, B., Judd, J., Goldin, B., Woods, M. N., Gorbach, S. L., & Lichtenstein, A. H. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/65.3.823 · Cited by 167 · see citing works
Mok, C. K., Boey, J. Y., Wang, R., Chan, T. K., Cheung, K. L., Lee, P. K., Chow, J. S. F., Ng, R. P., & Tse, T.-F. (1985) · Circulation · doi:10.1161/01.cir.72.5.1059 · Cited by 156 · see citing works
Obesity, Behavioral Lifestyle Factors, and Risk of Acute Coronary Events
Jensen, M. K., Chiuve, S. E., Rimm, E. B., Dethlefsen, C., Tjønneland, A. M., Joensen, A. M., & Overvad, K. (2008) · Circulation · doi:10.1161/circulationaha.107.759951 · Cited by 152 · see citing works
LaRosa, J. C., Grundy, S. M., Kastelein, J. J. P., Kostis, J. B., & Greten, H. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.03.102 · Cited by 148 · see citing works
Self-citationThomas, R. J., King, M. L., Lui, K., Oldridge, N., Piña, I. L., & Spertus, J. A. (2007) · Circulation · doi:10.1161/circulationaha.107.185734 · Cited by 147 · see citing works
Self-citationThiazolidinedione Drugs and Cardiovascular Risks
Kaul, S., Bolger, A. F., Herrington, D. M., Giugliano, R. P., & Eckel, R. H. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.02.014 · Cited by 143 · see citing works
Walther, C., Möbius-Winkler, S., Linke, A., Bruegel, M., Thiery, J., Schuler, G., & Halbrecht, R. (2008) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3282f29aa6 · Cited by 135 · see citing works
Optimizing Statin Treatment for Primary Prevention of Coronary Artery Disease
Hayward, R. A., Krumholz, H. M., Zulman, D. M., Timbie, J. W., & Vijan, S. S. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-152-2-201001190-00004 · Cited by 131 · see citing works
Gurfinkel, E. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)95374-7 · Cited by 130 · see citing works
Clark, A. M., Haykowsky, M. J., Kryworuchko, J., Maclure, T., Scott, J. M., DesMeules, M., Luo, W. P., Liang, Y., & McAlister, F. A. (2010) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e32833090ef · Cited by 127 · see citing works
Campeau, L., Hunninghake, D., Knatterud, G., White, C., Domanski, M., Forman, S., Forrester, J., Geller, N., Gobel, F., Herd, J., et al. (1999) · Circulation · doi:10.1161/01.cir.99.25.3241 · Cited by 123 · see citing works
Myocardial Infarction and Risk of Suicide
Larsen, K. K., Agerbo, E., Christensen, B., Søndergaard, J., & Vestergaard, M. (2010) · Circulation · doi:10.1161/circulationaha.110.956136 · Cited by 122 · see citing works
Schaefer, E., Lichtenstein, A., Lamon-Fava, S., Contois, J., Li, Z.-L., Rasmussen, H., Mcnamara, J., & Ordovás, J. (1995) · Arteriosclerosis, Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.8.1079 · Cited by 121 · see citing works
Thiazolidinedione Drugs and Cardiovascular Risks
Kaul, S., Bolger, A. F., Herrington, D. M., Giugliano, R. P., & Eckel, R. H. (2010) · Circulation · doi:10.1161/cir.0b013e3181d34114 · Cited by 117 · see citing works
Influenza Vaccination as Secondary Prevention for Cardiovascular Disease
Davis, M. M., Taubert, K. A., Benin, A. L., Brown, D. W., Mensah, G. A., Baddour, L. M., Dunbar, S. B., & Krumholz, H. M. (2006) · Circulation · doi:10.1161/circulationaha.106.178242 · Cited by 113 · see citing works
Self-citationBrar, S. S., Kim, J., Brar, S. K., Zadegan, R., Ree, M. H., Liu, I.-L. A., Mansukhani, P. W., Aharonian, V. J., Hyett, R., & Shen, A. Y. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.01.063 · Cited by 112 · see citing works
The effect of antiplatelet therapy on saphenous vein coronary artery bypass graft patency.
Sharma, G. V., Khuri, S. F., Josa, M., Folland, E. D., & Parisi, A. F. (1983) · PubMed · Cited by 110 · see citing works
Training physicians about smoking cessation
Cummings, S. R., Richard, R. J., Duncan, C. L., Hansen, B., Martin, R. V., Gerbert, B., & Coates, T. J. (1989) · Journal of General Internal Medicine · doi:10.1007/bf02599545 · Cited by 107 · see citing works
Routine Screening for Depression in Patients With Coronary Heart Disease
Ziegelstein, R. C., Thombs, B. D., Coyne, J. C., & de Jonge, P. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.01.082 · Cited by 91 · see citing works
Adult tobacco survey - 19 States, 2003-2007.
McClave, A. K., Whitney, N., Thorne, S. L., et al. (2010) · PubMed · Cited by 89 · see citing works
KMok, C., JBoey, RWang, KChan, T., LCheung, K., Klee, P., JChow, PNg, R., & FTse, T. (1985) · Circulation · Cited by 68 · see citing works
Effect on Cessation Counseling of Documenting Smoking Status as a Routine Vital Sign: An ACORN Study
Rothemich, S. F., Woolf, S. H., Johnson, R. E., Burgett, A. E., Flores, S. K., Marsland, D. W., & Ahluwalia, J. S. (2008) · The Annals of Family Medicine · doi:10.1370/afm.750 · Cited by 53 · see citing works
de Peuter, O. R., Lussana, F., Peters, R. J. G., Buller, H. R., & Kamphuisen, P. W. (2009) · PubMed · Cited by 50 · see citing works
Duncan, C. L., Stein, M. J., & Cummings, S. R. (1991) · American Journal of Public Health · doi:10.2105/ajph.81.7.899 · Cited by 48 · see citing works
Zhao, X., Brown, B., Hillger, L., Sacco, D., Bisson, B., Fisher, L., & Albers, J. (1993) · Circulation · doi:10.1161/01.cir.88.6.2744 · Cited by 38 · see citing works
Documenting smoking Status: Trial of three strategies.
Rosser, W., McDowell, I., & Newell, C. (1992) · PubMed · Cited by 14 · see citing works
Beta blockers for preventing stroke recurrence
Lima, L. G. D., Soares, B. G., Saconato, H., et al. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007890 · Cited by 2 · see citing works
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Research works printed but not linked: 3
- Wenger NK, Froelicher ES, Ades PA, Berra K, Blumenthal JA, Certo CME, Dattilo AM, Davis D, DeBusk RF, Drozda JP, Fletcher BJ, Franklin BA, Gaston H, Greenland P, McBride PE, McGregor CG, Oldridge NB, Piscatella JC, Rogers FJ. Cardiac Rehabilitation: Clinical Practice Guideline 17. Washington DC: US Department of Health Human Services; 1995. AHCPR publication No. 96–0672.
- 10.1056/NEJMoa040583 · DOI · Paper page
- 10.1161/CIRCULATIONAHA.106.174526 · DOI · Paper page
Cited by
Sorted by citations
James, S. L., Abate, D., Abate, K. H., Abay, S. M., Abbafati, C., Abbasi, N., Abbastabar, H., Abd-Allah, F., Abdela, J., Abdelalim, A., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)32279-7 · Cited by 13,867 · see citing works
Vos, T., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., Abdulkader, R. S., Abdulle, A. M., Abebo, T. A., Abera, S. F., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32154-2 · Cited by 13,220 · see citing works
2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.019 · Cited by 12,536 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000065 · Cited by 7,391 · see citing works
Self-citation2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk
Goff, D. C., Lloyd-Jones, D. M., Bennett, G., Coady, S., D’Agostino, R. B., Gibbons, R., Greenland, P., Lackland, D. T., Levy, D., O’Donnell, C. J., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.11.005 · Cited by 4,945 · see citing works
Self-citationWhelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Hypertension · doi:10.1161/hyp.0000000000000066 · Cited by 4,347 · see citing works
Self-citationGoff, D. C., Lloyd-Jones, D. M., Bennett, G., Coady, S., D’Agostino, R. B., Gibbons, R., Greenland, P., Lackland, D. T., Levy, D., O’Donnell, C. J., et al. (2014) · Circulation · doi:10.1161/01.cir.0000437741.48606.98 · Cited by 3,697 · see citing works
Self-citation2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes
Amsterdam, E. A., Wenger, N. K., Brindis, R. G., Casey, D. E., Ganiats, T. G., Holmes, D. R., Jaffe, A. S., Jneid, H., Kelly, R. F., Kontos, M. C., et al. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2014.09.017 · Cited by 3,595 · see citing works
Self-citationYancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829e8807 · Cited by 3,304 · see citing works
Heidenreich, P. A., Bozkurt, B., Aguilar, D., Allen, L. A., Byun, J. J., Colvin, M. M., Deswal, A., Drazner, M. H., Dunlay, S. M., Evers, L. R., et al. (2022) · Circulation · doi:10.1161/cir.0000000000001063 · Cited by 4,922 · see citing works
January, C. T., Wann, L. S., Alpert, J. S., Calkins, H., Cigarroa, J. E., Cleveland, J. C., Conti, J. B., Ellinor, P. T., Ezekowitz, M. D., Field, M. E., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000040 · Cited by 2,056 · see citing works
Self-citation2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease
Gerhard-Herman, M. D., Gornik, H. L., Barrett, C., Barshes, N. R., Corriere, M. A., Drachman, D. E., Fleisher, L. A., Fowkes, F. G. R., Hamburg, N. M., Kinlay, S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.11.007 · Cited by 1,941 · see citing works
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
Arnett, D. K., Blumenthal, R. S., Albert, M. A., Buroker, A. B., Goldberger, Z. D., Hahn, E. J., Himmelfarb, C. D., Khera, A., Lloyd-Jones, D., McEvoy, J. W., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.03.010 · Cited by 1,896 · see citing works
Self-citationExercise-Based Cardiac Rehabilitation for Coronary Heart Disease
Anderson, L., Oldridge, N., Thompson, D. R., Zwisler, A.-D., Rees, K., Martin, N., & Taylor, R. S. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.10.044 · Cited by 1,910 · see citing works
Exercise-based cardiac rehabilitation for coronary heart disease
Heran, B. S., Chen, J. M., Ebrahim, S., Moxham, T., Oldridge, N., Rees, K., Thompson, D. R., & Taylor, R. S. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001800.pub2 · Cited by 1,844 · see citing works
Stout, K. K., Daniels, C. J., Aboulhosn, J. A., Bozkurt, B., Broberg, C. S., Colman, J. M., Crumb, S. R., Dearani, J. A., Fuller, S., Gurvitz, M., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000603 · Cited by 1,602 · see citing works
Virani, S. S., Newby, L. K., Arnold, S. V., Bittner, V., Brewer, L. C., Demeter, S. H., Dixon, D. L., Fearon, W. F., Hess, B., Johnson, H. M., et al. (2023) · Circulation · doi:10.1161/cir.0000000000001168 · Cited by 1,598 · see citing works
Self-citationBillinger, S. A., Arena, R., Bernhardt, J., Eng, J. J., Franklin, B. A., Johnson, C. M., MacKay-Lyons, M., Macko, R. F., Mead, G. E., Roth, E. J., et al. (2014) · Stroke · doi:10.1161/str.0000000000000022 · Cited by 1,529 · see citing works
Self-citationAcute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association
Mehta, L. S., Beckie, T. M., DeVon, H. A., Grines, C. L., Krumholz, H. M., Johnson, M. N., Lindley, K. J., Vaccarino, V., Wang, T. Y., Watson, K. E., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000351 · Cited by 1,244 · see citing works
Lichtman, J. H., Froelicher, E. S., Blumenthal, J. A., Carney, R. M., Doering, L. V., Frasure-Smith, N., Freedland, K. E., Jaffe, A. S., Leifheit-Limson, E. C., Sheps, D. S., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000019 · Cited by 1,208 · see citing works
Effects of aspirin for primary prevention in persons with diabetes mellitus
The ASCEND Study Collaborative Group (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1804988 · Cited by 1,189 · see citing works
Whelton, P. K., Carey, R. M., Aronow, W. S., Casey, D. E., Collins, K. J., Dennison Himmelfarb, C., DePalma, S. M., Gidding, S., Jamerson, K. A., Jones, D. W., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000596 · Cited by 1,127 · see citing works
Self-citationMartin, S. S., Blaha, M. J., Elshazly, M. B., Toth, P. P., Kwiterovich, P. O., Blumenthal, R. S., & Jones, S. R. (2013) · JAMA · doi:10.1001/jama.2013.280532 · Cited by 883 · see citing works
Fihn, S. D., Gardin, J. M., Abrams, J., Berra, K., Blankenship, J. C., Dallas, A. P., Douglas, P. S., Foody, J. M., Gerber, T. C., Hinderliter, A. L., et al. (2012) · Circulation · doi:10.1161/cir.0b013e318277d6a0 · Cited by 845 · see citing works
Self-citationLin, X., Zhang, X., Guo, J., Roberts, C. K., McKenzie, S., Wu, W., Liu, S., & Song, Y. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.115.002014 · Cited by 758 · see citing works
Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
The ASCEND Study Collaborative Group (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1804989 · Cited by 698 · see citing works
β-Blocker Use and Clinical Outcomes in Stable Outpatients With and Without Coronary Artery Disease
Bangalore, S., Steg, G., Deedwania, P., Crowley, K., Eagle, K. A., Goto, S., Ohman, E. M., Cannon, C. P., Smith, S. C., Zeymer, U., et al. (2012) · JAMA · doi:10.1001/jama.2012.12559 · Cited by 436 · see citing works
Self-citationFranklin, B. A., Thompson, P. D., Al-Zaiti, S. S., Albert, C. M., Hivert, M.-F., Levine, B. D., Lobelo, F., Madan, K., Sharrief, A. Z., Eijsvogels, T. M. H., et al. (2020) · Circulation · doi:10.1161/cir.0000000000000749 · Cited by 410 · see citing works
Self-citationAl-Khatib, S. M., Stevenson, W. G., Ackerman, M. J., Bryant, W. J., Callans, D. J., Curtis, A. B., Deal, B. J., Dickfeld, T., Field, M. E., Fonarow, G. C., et al. (2018) · Circulation · doi:10.1161/cir.0000000000000548 · Cited by 412 · see citing works
Vaccarino, V., Badimon, L., Bremner, J. D., Cenko, E., Cubedo, J., Dorobantu, M., Duncker, D. J., Koller, A., Manfrini, O., Milicic, D., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehy913 · Cited by 404 · see citing works
Forman, D. E., Arena, R., Boxer, R., Dolansky, M. A., Eng, J. J., Fleg, J. L., Haykowsky, M., Jahangir, A., Kaminsky, L. A., Kitzman, D. W., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000483 · Cited by 319 · see citing works
Serban, M.-C., Colantonio, L. D., Manthripragada, A. D., Monda, K. L., Bittner, V. A., Banach, M., Chen, L., Huang, L., Dent, R., Kent, S. T., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.12.036 · Cited by 318 · see citing works
Clinical Outcomes with β-Blockers for Myocardial Infarction: A Meta-analysis of Randomized Trials
Bangalore, S., Makani, H., Radford, M., Thakur, K., Toklu, B., Katz, S. D., DiNicolantonio, J. J., Devereaux, P. J., Alexander, K. P., Wetterslev, J., et al. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.05.032 · Cited by 315 · see citing works
Pet Ownership and Cardiovascular Risk: A Scientific Statement From the American Heart Association
Levine, G. N., Allen, K., Braun, L. T., Christian, H. E., Friedmann, E., Taubert, K. A., Thomas, S. A., Wells, D. L., & Lange, R. A. (2013) · Circulation · doi:10.1161/cir.0b013e31829201e1 · Cited by 299 · see citing works
The mobile revolution—using smartphone apps to prevent cardiovascular disease
Neubeck, L., Lowres, N., Benjamin, E. J., Freedman, S. B., Coorey, G., & Redfern, J. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.34 · Cited by 232 · see citing works
Self-citationEndothelial dysfunction and coronary artery disease: assessment, prognosis, and treatment
Matsuzawa, Y., & Lerman, A. (2014) · Coronary Artery Disease · doi:10.1097/mca.0000000000000178 · Cited by 249 · see citing works
Better Population Health Through Behavior Change in Adults: A Call to Action
Spring, B., Ockene, J. K., Gidding, S. S., Mozaffarian, D., Moore, S., Rosal, M. C., Brown, M. D., Vafiadis, D. K., Cohen, D. L., Burke, L. E., et al. (2013) · Circulation · doi:10.1161/01.cir.0000435173.25936.e1 · Cited by 195 · see citing works
Self-citationThe Current State of Niacin in Cardiovascular Disease Prevention
Lavigne, P. M., & Karas, R. H. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.10.030 · Cited by 185 · see citing works
Beatty, A. L., Schiller, N. B., & Whooley, M. A. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2012.2198 · Cited by 174 · see citing works
Novel Wireless Devices for Cardiac Monitoring
Walsh, J. A., Topol, E. J., & Steinhubl, S. R. (2014) · Circulation · doi:10.1161/circulationaha.114.009024 · Cited by 175 · see citing works
Hollings, M., Mavros, Y., Freeston, J., & Fiatarone Singh, M. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487317713329 · Cited by 148 · see citing works
Living alone and cardiovascular risk in outpatients at risk of or with atherothrombosis
Steg, P. G. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2012.2782 · Cited by 133 · see citing works
Li, Y., Jiang, L., Jia, Z., Xin, W., Yang, S., Yang, Q., & Wang, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098611 · Cited by 124 · see citing works
Vadiveloo, M., Lichtenstein, A. H., Anderson, C., Aspry, K., Foraker, R., Griggs, S., Hayman, L. L., Johnston, E., Stone, N. J., Thorndike, A. N., et al. (2020) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/hcq.0000000000000094 · Cited by 112 · see citing works
Neuman, M. D., Goldstein, J. N., Cirullo, M. A., & Schwartz, J. S. (2014) · JAMA · doi:10.1001/jama.2014.4949 · Cited by 89 · see citing works
Armstrong, M. J., Sigal, R. J., Arena, R., Hauer, T. L., Austford, L. D., Aggarwal, S., Stone, J. A., & Martin, B.-J. (2015) · Diabetologia · doi:10.1007/s00125-015-3491-1 · Cited by 60 · see citing works
Physical activity and structured exercise for patients with stable ischemic heart disease
Boden, W. E., Franklin, B. A., & Wenger, N. K. (2013) · JAMA · doi:10.1001/jama.2012.128367 · Cited by 57 · see citing works
Self-citationShang, W., Zhang, Y., Wang, G., & Han, D. (2021) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.14247 · Cited by 50 · see citing works
Patients with Diabetes in Cardiac Rehabilitation: Attendance and Exercise Capacity
ARMSTRONG, M. J., MARTIN, B.-J., ARENA, R., HAUER, T. L., AUSTFORD, L. D., STONE, J. A., AGGARWAL, S., & SIGAL, R. J. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000189 · Cited by 41 · see citing works
Barrat, E., Zaïr, Y., Sirvent, P., Chauveau, P., Maudet, C., Housez, B., Derbord, E., Lescuyer, J.-F., Bard, J.-M., Cazaubiel, M., et al. (2013) · European Journal of Nutrition · doi:10.1007/s00394-012-0486-2 · Cited by 31 · see citing works
Patel, M. R., Calhoon, J. H., Dehmer, G. J., Grantham, J. A., Maddox, T. M., Maron, D. J., & Smith, P. K. (2018) · Journal of Nuclear Cardiology · doi:10.1007/s12350-018-1292-x · Cited by 11 · see citing works
- Authors
- Smith, S. C., Benjamin, E. J., Bonow, R. O., Braun, L. T., Creager, M. A., Franklin, B. A., Gibbons, R. J., Grundy, S. M., Hiratzka, L. F., Jones, D. W., Lloyd-Jones, D. M., Minissian, M., Mosca, L., Peterson, E. D., Sacco, R. L., Spertus, J., Stein, J. H., & Taubert, K. A.
- ORCID
- Venue
- Circulation
- Published
- 2011-11-29
- Volume
- 124
- Issue
- 22
- Pages
- 2458-2473
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2144663588
- Semantic Scholar
- d0122e404230e9e36a5a2c690ed5bb6094b9ff52
- Cited by
- 1,759
- References
- 195
- Citations by year
- 2026: 35 · 2025: 55 · 2024: 68 · 2023: 78 · 2022: 111 · 2021: 107 · 2020: 116 · 2019: 129 · 2018: 143 · 2017: 166 · 2016: 143 · 2015: 157 · 2014: 161 · 2013: 168 · 2012: 109
- FWCI
- 99.20
- Type
- journal article
- Language
- en
- Update notices
- correction (2015-04-14)
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Funders
- World Heart Federation
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Antiplatelet Therapy and Cardiovascular Diseases
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Keywords
- secondary prevention, cardiovascular risk reduction, coronary artery disease, atherosclerosis, guideline revision, lipid-lowering therapy, antithrombotic therapy, statins, aspirin
- MeSH terms
- American Heart Association, Coronary Artery Disease, Humans, Societies, Medical, United States, Risk Reduction Behavior
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-10.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-10.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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